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1. 发明申请

US20060129216A1 Stimulation of cell growth at implant surfaces 有权
标题翻译：刺激植入物表面的细胞生长
公开(公告)号：US20060129216A1
公开(公告)日：2006-06-15
申请号：US11011263
申请日：2004-12-14
申请人： Roger Hastings , William Drasler , Mark Jenson
发明人： Roger Hastings , William Drasler , Mark Jenson
IPC分类号： A61N1/02
CPC分类号： A61F2/86 , A61B5/0215 , A61B5/042 , A61B5/076 , A61B5/445 , A61B2560/0219 , A61B2562/02 , A61B2562/0247 , A61F2/06 , A61F2/91 , A61L27/34 , A61L27/50 , A61N1/02 , A61N1/326 , A61N1/362 , A61N1/375
摘要： The present invention is directed to medical devices that contain at least one tissue contacting surface that is configured to undergo a variation in surface charge in response to a time-dependent signal. Such a variation in surface charge is provided, for example, to enhance or inhibit cellular growth adjacent to, on, or within the at least one tissue contacting surface.
摘要翻译：本发明涉及包含至少一个组织接触表面的医疗装置，该组织接触表面被配置为响应于时间依赖性信号而经历表面电荷的变化。提供这种表面电荷的变化，例如，以增强或抑制邻近于，在或在至少一个组织接触表面附近的细胞生长。

2. 发明授权

US07789893B2 Method and apparatus for promoting hemostasis of a blood vessel puncture 有权
标题翻译：促进血管穿刺止血的方法和装置
公开(公告)号：US07789893B2
公开(公告)日：2010-09-07
申请号：US11531143
申请日：2006-09-12
申请人： William Drasler , Mark Jenson , Jason P. Hill
发明人： William Drasler , Mark Jenson , Jason P. Hill
IPC分类号： A61D1/00
CPC分类号： A61B17/0057 , A61B2017/00641
摘要： An apparatus for promoting hemostasis of a puncture formed in a blood vessel accessible through an incision tract and methods of use thereof. The apparatus includes distal and proximal balloons each having a contracted position and an expanded position, the proximal balloon spaced by a predetermined initial distance from the distal balloon. The apparatus further includes at least one catheter coupling the distal and proximal balloons to a source of pressurized fluid to selectively actuate the distal and proximal balloons between the contracted and expanded positions.
摘要翻译：一种用于促进形成在可通过切口引导的血管中形成的穿刺止血的装置及其使用方法。该装置包括远端和近端气球，其各自具有收缩位置和扩张位置，近侧气球与远端球囊隔开预定的初始距离。该装置还包括至少一个导管，其将远端和近端气囊联接到加压流体源，以选择性地致动收缩和扩张位置之间的远端和近端气囊。

3. 发明申请

US20080065150A1 Method and Apparatus for Promoting Hemostasis of a Blood Vessel Puncture 有权
标题翻译：促进血管穿刺止血的方法和装置
公开(公告)号：US20080065150A1
公开(公告)日：2008-03-13
申请号：US11531143
申请日：2006-09-12
申请人： William Drasler , Mark Jenson , Jason P. Hill
发明人： William Drasler , Mark Jenson , Jason P. Hill
IPC分类号： A61B17/03
CPC分类号： A61B17/0057 , A61B2017/00641
摘要： An apparatus for promoting hemostasis of a puncture formed in a blood vessel accessible through an incision tract. The apparatus includes a distal balloon having a contacted position, in which a profile of the distal balloon is sized for insertion through the blood vessel puncture, an expanded position, in which the distal balloon profile prevents passage through the blood vessel puncture. The apparatus also includes a proximal balloon spaced by a predetermined initial distance from the distal balloon and having a contracted position, in which a profile of the proximal balloon is sized for insertion through the incision tract, and an expanded position, in which the proximal balloon profile blocks passage through the blood vessel puncture. The apparatus further includes at least one catheter coupling the distal and proximal balloons to a source of pressurized fluid to selectively actuate the distal and proximal balloons between the contracted and expanded positions. And, the apparatus includes at least one rigid positioner associated with the at least one catheter to facilitate movement of the distal and proximal balloons proximally through the incision tract. The catheter has a flexible wall portion extending proximally of the distal and proximal balloons to facilitate everting of the distal and proximal balloons as the catheter is proximally withdrawn from the incision tract.
摘要翻译：一种用于促进形成在通过切口可通过的血管中形成的穿刺止血的装置。该装置包括具有接触位置的远端球囊，其中远端球囊的轮廓的尺寸设置成插入通过血管穿刺，扩张位置，其中远侧球囊形状防止通过血管穿刺。该装置还包括与远端球囊隔开预定的初始距离并且具有收缩位置的近端球囊，其中近端球囊的轮廓的尺寸被设计成用于插入通过切开管道，以及扩张位置，其中近端球囊轮廓块通过血管穿刺。该装置还包括至少一个导管，其将远端和近端气囊联接到加压流体源，以选择性地致动收缩和扩张位置之间的远端和近端气囊。并且，该装置包括与至少一个导管相关联的至少一个刚性定位器，以便于远端和近端球囊向近侧移动通过切口。导管具有在远端和近端气囊的近侧延伸的柔性壁部分，以便当导管从切开道向近端退出时便于远端和近端气囊的远端。

4. 发明申请

US20060293612A1 Apparatus and method for treating occluded vasculature 审中-公开
标题翻译：用于治疗闭塞性脉管系统的装置和方法
公开(公告)号：US20060293612A1
公开(公告)日：2006-12-28
申请号：US11354377
申请日：2006-02-15
申请人： Mark Jenson , William Drasler
发明人： Mark Jenson , William Drasler
IPC分类号： A61M25/00
CPC分类号： A61B17/3207 , A61B2017/00398 , A61B2017/22044 , A61B2017/22077 , A61B2017/22094 , A61M25/0084 , A61M25/0138 , A61M2025/0046 , A61M2025/0063 , A61M2025/1093
摘要： Occluded vasculature such as occluded arterial vasculature can be recanalized using a device that is configured to penetrate an occlusion, while limiting a distance that said penetration structure can extend in order to limit inadvertent vascular damage. The device can include an elongate shaft of a guidewire and a stylet disposed within a lumen of the elongate shaft such that the stylet is selectively actuatable within the elongate shaft.
摘要翻译：封闭的脉管系统如闭塞的动脉脉管系统可以使用被配置为穿透闭塞的装置再次通气，同时限制所述穿透结构可以延伸的距离，以限制无意的血管损伤。该装置可以包括导丝的细长轴和设置在细长轴的内腔中的探针，使得探针可以在细长轴内选择性地致动。

5. 发明申请

US20050288695A1 Apparatus and method for treating occluded vasculature 有权
标题翻译：用于治疗闭塞性脉管系统的装置和方法
公开(公告)号：US20050288695A1
公开(公告)日：2005-12-29
申请号：US10877340
申请日：2004-06-24
申请人： Mark Jenson , William Drasler , Daniel Lafontaine
发明人： Mark Jenson , William Drasler , Daniel Lafontaine
IPC分类号： A61B17/00 , A61B17/22
CPC分类号： A61B17/3207 , A61B2017/00398 , A61B2017/22044 , A61B2017/22077
摘要： Occluded vasculature such as occluded arterial vasculature can be recanalized using a device that is configured to penetrate an occlusion, while limiting a distance that said penetration structure can extend in order to limit inadvertent vascular damage. The device can include an elongate sheath and a stylet disposed within the elongate sheath. The elongate sheath and the stylet can include, in combination, an engagement section that is configured to limit relative axial movement between the elongate sheath and the stylet.
摘要翻译：封闭的脉管系统如闭塞的动脉脉管系统可以使用被配置为穿透闭塞的装置再次通气，同时限制所述穿透结构可以延伸的距离，以限制无意的血管损伤。该装置可以包括细长护套和设置在细长护套内的探针。细长护套和探针可以组合地包括被配置为限制细长护套和探针之间的相对轴向运动的接合部分。

6. 发明申请

US20050288618A1 Myocardial treatment apparatus and method 审中-公开
标题翻译：心肌治疗仪及方法
公开(公告)号：US20050288618A1
公开(公告)日：2005-12-29
申请号：US10877331
申请日：2004-06-24
申请人： Mark Jenson , William Drasler
发明人： Mark Jenson , William Drasler
IPC分类号： A61B17/00 , A61B17/32 , A61F2/02 , A61F2/06 , A61M39/00
CPC分类号： A61B17/320016 , A61B2017/00243 , A61F2/064 , A61F2/2493
摘要： Apparatus and methods for forming a conduit through an infarcted region where the conduit is in fluid communication with a supply of oxygenated blood and the venous vasculature and flowing oxygenated blood from the supply of oxygenated blood through the conduit and to the venous vasculature.
摘要翻译：用于通过梗塞区域形成导管的装置和方法，其中所述导管与氧合血液供应和所述静脉血管和来自氧合血液供应的流动的氧合血液通过导管和静脉血管流体连通。

7. 发明申请

US20090082827A1 HINGED ANCHORS FOR WIRELESS PACING ELECTRODES 审中-公开
标题翻译：无线电缆铰链锚杆
公开(公告)号：US20090082827A1
公开(公告)日：2009-03-26
申请号：US11861911
申请日：2007-09-26
申请人： Graig Kveen , Douglas Saholt , Joseph Thielen , Mark Jenson , William Drasler
发明人： Graig Kveen , Douglas Saholt , Joseph Thielen , Mark Jenson , William Drasler
IPC分类号： A61N1/362
CPC分类号： A61N1/375 , A61N1/0573 , A61N1/37205 , A61N1/3756
摘要： A hinged anchor for a medical device electrode is disclosed. In one embodiment, the hinged anchor has a hinged portion and an anchor portion. The hinged portion can have a first configuration forming a first angle and a second configuration forming a second angle. The second angle can be a sharper angle than the first angle, and the hinged portion can be predisposed to assume the second configuration. The hinged anchor can be disposed on a control module of a leadless microstimulator device.
摘要翻译：公开了一种用于医疗器械电极的铰接锚。在一个实施例中，铰接锚固件具有铰接部分和锚定部分。铰链部分可以具有形成第一角度的第一构造和形成第二角度的第二构造。第二角度可以是比第一角度更尖锐的角度，并且铰链部分可以被预先设置成呈现第二构造。铰链锚可以设置在无引线微型激励器装置的控制模块上。

8. 发明申请

US20070129788A1 Venous valve with sinus 审中-公开
标题翻译：静脉瓣与鼻窦
公开(公告)号：US20070129788A1
公开(公告)日：2007-06-07
申请号：US11652299
申请日：2007-01-11
申请人： William Drasler , Mark Jenson , Jason Hill , David Sogard , Patrick Haverkost , Susan Shoemaker
发明人： William Drasler , Mark Jenson , Jason Hill , David Sogard , Patrick Haverkost , Susan Shoemaker
IPC分类号： A61F2/06
CPC分类号： A61F2/2475 , A61F2/06 , A61F2/2412 , A61F2/2418 , A61F2/2436 , A61F2210/0014 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2230/0013 , A61F2250/0098 , Y10T29/49405
摘要： A venous valve-with a structural member and valve leaflets that provide a sinus.
摘要翻译：静脉瓣 - 具有结构构件和提供窦的瓣叶。

9. 发明申请

US20060173490A1 Filter system and method 审中-公开
标题翻译：过滤系统和方法
公开(公告)号：US20060173490A1
公开(公告)日：2006-08-03
申请号：US11049019
申请日：2005-02-01
申请人： Daniel Lafontaine , Mark Jenson , William Drasler
发明人： Daniel Lafontaine , Mark Jenson , William Drasler
IPC分类号： A61M29/00
CPC分类号： A61F2/2418 , A61F2/01 , A61F2/013 , A61F2/2433 , A61F2/958 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2210/0019 , A61F2220/005 , A61F2220/0066 , A61F2230/0006 , A61F2230/0069 , A61F2230/008
摘要： A filter system, comprising an elongate filter body defining a lumen and having a proximal end and a distal end. A valve can be provided defining a lumen and having a reversibly sealable opening for unidirectional flow of a fluid through the lumen. The valve can be adjoined proximal the distal end of the elongate filter body, wherein the elongate filter body filters the unidirectional flow of the fluid passing through the lumen of the valve and the lumen of the elongate filter body.
摘要翻译：一种过滤系统，包括限定内腔并具有近端和远端的细长过滤体。可以提供限定内腔的阀，并且具有可逆地密封的开口，用于流体通过内腔的单向流动。瓣膜可以在细长过滤体的远端附近邻接，其中细长的过滤器主体过滤通过阀的内腔和细长过滤体的内腔的单向流动。

10. 发明申请

US20060173475A1 Vascular catheter, system, and method 有权
标题翻译：血管导管，系统和方法
公开(公告)号：US20060173475A1
公开(公告)日：2006-08-03
申请号：US11049000
申请日：2005-02-01
申请人： Daniel Lafontaine , Mark Jenson , William Drasler
发明人： Daniel Lafontaine , Mark Jenson , William Drasler
IPC分类号： A61B17/22
CPC分类号： A61B17/32075 , A61B90/39 , A61B2017/00243 , A61B2017/22097 , A61F2/958
摘要： A catheter including an elongate body, a first cutting head and a second cutting head both having a blade, where the blades moves relative each other to provide a shearing action for cardiac tissue. The catheter can further include a stent positioned over an inflatable balloon, where the inflatable balloon can deploy the expandable stent over sheared cardiac tissue. The catheter can further be included in a system having a sheath, where at least a part of the catheter resides in the lumen of the sheath. The sheath further includes a cardiac valve and an expandable filter. The sheath can move relative the cardiac valve and the expandable filter to deploy the cardiac valve and at least a portion of the expandable filter proximal the inflatable balloon and the expandable stent.
摘要翻译：一种导管，其包括细长体，第一切割头和具有叶片的第二切割头，其中所述刀片相对于彼此移动以提供用于心脏组织的剪切动作。导管还可以包括定位在可膨胀气球上的支架，其中可充气球囊可以在可剪切的心脏组织上展开可扩张支架。导管可以进一步包括在具有护套的系统中，其中导管的至少一部分位于鞘的内腔中。护套还包括心脏瓣膜和可膨胀过滤器。护套可以相对于心脏瓣膜和可膨胀过滤器移动，以将心脏瓣膜部署，并且可扩张过滤器的至少一部分靠近可充气球囊和可扩张支架。

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