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1. 发明授权

US12011592B2 Adaptive trigger for a microcurrent stimulation device 有权
公开(公告)号：US12011592B2
公开(公告)日：2024-06-18
申请号：US16664085
申请日：2019-10-25
申请人： TIVIC HEALTH SYSTEMS INC.
发明人： John Claude , Christopher A. Wiklof
IPC分类号： A61N1/08 , A61B5/053 , A61N1/02 , A61N1/04 , A61N1/20 , A61N1/36 , A61B5/00 , A61B18/14 , A61N1/32
CPC分类号： A61N1/36031 , A61B5/053 , A61N1/02 , A61N1/025 , A61N1/04 , A61N1/0428 , A61N1/0456 , A61N1/0472 , A61N1/08 , A61N1/205 , A61N1/36 , A61N1/3601 , A61N1/36014 , A61N1/36021 , A61N1/36034 , A61B5/6814 , A61B5/7225 , A61B18/14 , A61N2001/083 , A61N1/326 , A61N1/3603
摘要： A microcurrent treatment device includes an adaptive trigger circuit configured to dynamically determine a triggering threshold for applying a therapeutic microcurrent via a treatment electrode to a nerve node on a person's face for treatment of a sinus condition.

2. 发明授权

US11957893B2 Minimally invasive implantable neurostimulation system 有权
公开(公告)号：US11957893B2
公开(公告)日：2024-04-16
申请号：US16947944
申请日：2020-08-25
申请人： Medtronic, Inc.
发明人： Brad C. Tischendorf , John E. Kast , Thomas P. Miltich , Gordon O. Munns , Randy S. Roles , Craig L. Schmidt , Joseph J. Viavattine , Christian S. Nielsen , Prabhakar A. Tamirisa , Anthony M. Chasensky , Markus W. Reiterer , Chris J. Paidosh , Reginald D. Robinson , Bernard Q. Li , Erik R. Scott , Phillip C. Falkner , Xuan K. Wei , Eric H. Bonde , David A. Dinsmoor , Duane L. Bourget , Forrest C M Pape , Gabriela C. Molnar , Joel A. Anderson , Michael J. Ebert , Richard T. Stone , Shawn C. Kelley , Stephen J. Roddy , Timothy J. Denison , Todd V. Smith
IPC分类号： A61N1/02 , A61B17/00 , A61N1/05 , A61N1/36 , A61N1/372 , A61N1/375 , A61N1/378
CPC分类号： A61N1/02 , A61B17/00234 , A61N1/05 , A61N1/0551 , A61N1/36007 , A61N1/3605 , A61N1/36057 , A61N1/36067 , A61N1/36071 , A61N1/36139 , A61N1/37205 , A61N1/37223 , A61N1/37235 , A61N1/37247 , A61N1/3727 , A61N1/3754 , A61N1/3756 , A61N1/3787 , A61N1/36021 , A61N1/36053 , A61N1/37211 , A61N1/37518 , F04C2270/0421
摘要： A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

3. 发明申请

US20180333569A1 A DEVICE AND MEANS OF ASSESSING NEUROMUSCULAR JUNCTION STATUS WITH HIGHER FIDELITY 审中-公开
公开(公告)号：US20180333569A1
公开(公告)日：2018-11-22
申请号：US15529928
申请日：2015-11-25
申请人： SafeOp Surgical, Inc.
发明人： Robert Snow , Richard O'Brien
IPC分类号： A61N1/02 , G16H20/40
CPC分类号： A61N1/02 , A61B5/04001 , A61B5/0488 , A61B5/4821 , A61B5/4839 , A61B2505/05 , G16H20/40
摘要： Devices and methods for stimulation and recording of muscle responses for determining degree of neuromuscular blockade, particularly relevant to elicitation of such responses in those under the influence of anesthesia. A system for estimating the degree of neuromuscular blockade includes at least one stimulating electrode, at least one recording electrode, a pulse generator for providing stimulation to a nerve through the stimulating electrode, and a computing device configured to: apply stimuli to the nerve according to a stimulation protocol, wherein the stimulation protocol provides a plurality of stimulation sequences that vary in frequency of pulses in the stimulation sequence, frequency of the stimulation sequences, number of pulses in the stimulation sequence, or all of the above; measure, by the recording electrode, electrical responses of a muscle; and estimate the degree of neuromuscular blockade based on changes in the electrical responses of the muscle during a stimulation sequence.

4. 发明授权

US09931107B2 Minimally invasive implantable neurostimulation system 有权
公开(公告)号：US09931107B2
公开(公告)日：2018-04-03
申请号：US14098621
申请日：2013-12-06
申请人： Medtronic, Inc.
发明人： Brad C. Tischendorf , Eric H. Bonde , Phillip C. Falkner , John E. Kast , Randy S. Roles , Erik R. Scott , Todd V. Smith , Xuan K. Wei , Anthony M. Chasensky , Michael J. Ebert , Shawn C. Kelley , Gabriela C. Molnar , Richard T. Stone
IPC分类号： A61N1/05 , A61B17/00 , A61N1/36 , A61N1/372 , A61N1/378 , A61N1/02 , A61N1/375
CPC分类号： A61B17/00234 , A61N1/02 , A61N1/05 , A61N1/0551 , A61N1/36 , A61N1/36007 , A61N1/36021 , A61N1/3605 , A61N1/36053 , A61N1/36057 , A61N1/36067 , A61N1/36071 , A61N1/36139 , A61N1/37205 , A61N1/37211 , A61N1/37223 , A61N1/37235 , A61N1/37247 , A61N1/37252 , A61N1/3727 , A61N1/375 , A61N1/3754 , A61N1/3756 , A61N1/3787 , F04C2270/0421
摘要： A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

5. 发明申请

US20160035967A1 IMPLANTABLE WIRELESS ACCOUSTIC STIMULATORS WITH HIGH ENERGY CONVERSION EFFICIENCIES 有权
公开(公告)号：US20160035967A1
公开(公告)日：2016-02-04
申请号：US14883925
申请日：2015-10-15
申请人： EBR Systems, Inc.
发明人： David F. Moore , Paul Mohr , N. Parker Willis , Axel F. Brisken
IPC分类号： H01L41/25 , A61N1/378
CPC分类号： A61N1/3787 , A61B2560/0214 , A61N1/02 , A61N1/05 , A61N1/362 , A61N1/37205 , A61N1/3756 , A61N1/3758 , H01L41/113 , H01L41/25 , H02N2/181 , H02N2/186 , H02N2/188 , Y10T29/42
摘要： Receiver-stimulator with folded or rolled up assembly of piezoelectric components, causing the receiver-stimulator to operate with a high degree of isotropy are disclosed. The receiver-stimulator comprises piezoelectric components, rectifier circuitry, and at least two stimulation electrodes. Isotropy allows the receiver-stimulator to be implanted with less concern regarding the orientation relative the transmitted acoustic field from an acoustic energy source.

6. 发明授权

US09173678B2 Transobturator lead implantation for pelvic floor stimulation 有权
标题翻译： Transobturator铅植入用于盆底刺激
公开(公告)号：US09173678B2
公开(公告)日：2015-11-03
申请号：US12819780
申请日：2010-06-21
申请人： Steven W. Siegel , Eric H. Bonde , Martin T. Gerber
发明人： Steven W. Siegel , Eric H. Bonde , Martin T. Gerber
IPC分类号： A61B17/00 , A61B17/34 , A61N1/02 , A61N1/05 , A61N1/36
CPC分类号： A61B17/3468 , A61B17/3415 , A61B17/3421 , A61B2017/00039 , A61B2017/00238 , A61B2017/00805 , A61N1/02 , A61N1/0551 , A61N1/0558 , A61N1/36007
摘要： The disclosure is directed to a method and tool for implanting a stimulation lead or other medical device adjacent a pudendal nerve. The tool includes a shaped needle that enters a patient and passes through an obturator foramen passage in a pelvis. A physician places a tip of the tool at the pudendal nerve and performs test stimulation to confirm an effective stimulation location. A shape memory cannula initially covering the needle remains at the pudendal nerve when the physician removes the tool. The cannula deforms to follow the curve of the pudendal nerve once the needle is removed, and a lead is inserted into the cannula and secured at the pudendal nerve placement site. This method may provide an easier and more consistent procedure for implanting the stimulation lead near the pudendal nerve.
摘要翻译：本公开涉及用于将刺激引线或其他医疗装置植入邻近的阴部神经的方法和工具。该工具包括成形的针，其进入患者并穿过骨盆中的闭孔通孔。医生将工具的尖端放置在阴部神经处，并执行测试刺激以确认有效的刺激位置。当医生取出工具时，最初覆盖针的形状记忆套管保留在阴部神经处。一旦取出针，套管就会变形成跟随阴部神经的曲线，并将导线插入插管并固定在阴部神经放置部位。该方法可以提供在阴部神经附近植入刺激引线更容易和更一致的过程。

7. 发明申请

US20150270025A1 CERAMIC BUSHING FOR AN IMPLANTABLE MEDICAL DEVICE 有权
标题翻译：一种可植入医疗器械的陶瓷衬套
公开(公告)号：US20150270025A1
公开(公告)日：2015-09-24
申请号：US14729560
申请日：2015-06-03
申请人： Heraeus Precious Metals GmbH & Co. KG
发明人： Heiko Specht , Jeremy Glynn
IPC分类号： H01B1/02 , H01R43/20 , A61N1/02 , H02G15/013 , H01B13/00
CPC分类号： H01B1/023 , A61N1/02 , A61N1/3754 , H01B1/02 , H01B13/00 , H01R43/02 , H02G15/013 , H04R2225/67 , Y10T29/49169 , Y10T29/49206
摘要： An electrical bushing for use in a housing of an implantable medical device is proposed. The electrical bushing includes at least one electrically insulating base body and at least one electrical conducting element. The conducting element establishes, through the base body, at least one electrically conductive connection between an internal space of the housing and an external space. The conducting element is hermetically sealed with respect to the base body, at least in part. The at least one conducting element includes at least one cermet. The cermet of the conducting element and the base body include one or more of the same ceramic compound.
摘要翻译：提出了用于可植入医疗装置的壳体中的电气套管。电气套管包括至少一个电绝缘基体和至少一个导电元件。导电元件通过基体设置在壳体的内部空间与外部空间之间的至少一个导电连接。导电元件至少部分地相对于基体气密地密封。至少一个导电元件包括至少一个金属陶瓷。导电元件和基体的金属陶瓷包括一种或多种相同的陶瓷化合物。

8. 发明授权

US08886317B2 MRI operation modes for implantable medical devices 有权
标题翻译：可植入医疗器械的MRI操作模式
公开(公告)号：US08886317B2
公开(公告)日：2014-11-11
申请号：US14027812
申请日：2013-09-16
申请人： Cardiac Pacemakers, Inc.
发明人： Daniel J. Cooke , Jeffrey A. Von Arx
IPC分类号： A61N1/37 , A61N1/39 , A61N1/368 , A61N1/02
CPC分类号： A61N1/3718 , A61N1/02 , A61N1/36092 , A61N1/3688 , A61N1/3931 , A61N1/3962 , Y10S128/901
摘要： One embodiment of the present invention relates to an implantable medical device (“IMD”) that can be programmed from one operational mode to another operational mode when in the presence of electro-magnetic interference (“EMI”). In accordance with this particular embodiment, the IMD includes a communication interface for receiving communication signals from an external device, such as a command to switch the IMD from a first operation mode to a second operation mode. The IMD further includes a processor in electrical communication with the communication interface, which is operable to switch or reprogram the IMD from the first operation mode to the second operation mode upon receiving a command to do so. In addition, the IMD includes a timer operable to measure a time period from when the processor switches the IMD to the second operation mode. In accordance with this aspect of the invention, the processor is in electrical communication with the timer, and is further operable to switch the IMD from the second operation mode back to the first operation mode when the measured time period reaches a predetermined time period.
摘要翻译：本发明的一个实施例涉及当存在电磁干扰（“EMI”）时可从一个操作模式编程到另一个操作模式的可植入医疗装置（“IMD”）。根据该特定实施例，IMD包括用于从外部设备接收通信信号的通信接口，诸如将IMD从第一操作模式切换到第二操作模式的命令。 IMD还包括与通信接口电通信的处理器，其可操作以在接收到这样做的命令时将IMD从第一操作模式切换或重新编程到第二操作模式。另外，IMD包括一个定时器，可操作以测量从处理器将IMD切换到第二操作模式的时间段。根据本发明的这个方面，处理器与定时器电通信，并且当测量的时间段达到预定的时间周期时，进一步可操作地将IMD从第二操作模式切换回第一操作模式。

9. 发明授权

US08588926B2 Implantable wireless accoustic stimulators with high energy conversion efficiencies 有权
公开(公告)号：US08588926B2
公开(公告)日：2013-11-19
申请号：US13734680
申请日：2013-01-04
申请人： David F. Moore , Paul Mohr , N. Parker Willis , Axel F. Brisken
发明人： David F. Moore , Paul Mohr , N. Parker Willis , Axel F. Brisken
IPC分类号： A61N1/375
CPC分类号： A61N1/3787 , A61B2560/0214 , A61N1/02 , A61N1/05 , A61N1/362 , A61N1/37205 , A61N1/3756 , A61N1/3758 , H01L41/113 , H01L41/25 , H02N2/181 , H02N2/186 , H02N2/188 , Y10T29/42
摘要： Receiver-stimulator with folded or rolled up assembly of piezoelectric components, causing the receiver-stimulator to operate with a high degree of isotropy are disclosed. The receiver-stimulator comprises piezoelectric components, rectifier circuitry, and at least two stimulation electrodes. Isotropy allows the receiver-stimulator to be implanted with less concern regarding the orientation relative the transmitted acoustic field from an acoustic energy source.

10. 发明申请

US20120193117A1 CERAMIC BUSHING FOR AN IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：一种可植入医疗器械的陶瓷衬套
公开(公告)号：US20120193117A1
公开(公告)日：2012-08-02
申请号：US13361322
申请日：2012-01-30
申请人： Heiko Specht , Jeremy Glynn
发明人： Heiko Specht , Jeremy Glynn
IPC分类号： H05K5/06 , H01R43/20
CPC分类号： H01B1/023 , A61N1/02 , A61N1/3754 , H01B1/02 , H01B13/00 , H01R43/02 , H02G15/013 , H04R2225/67 , Y10T29/49169 , Y10T29/49206
摘要： An electrical bushing for use in a housing of an implantable medical device is proposed. The electrical bushing includes at least one electrically insulating base body and at least one electrical conducting element. The conducting element establishes, through the base body, at least one electrically conductive connection between an internal space of the housing and an external space. The conducting element is hermetically sealed with respect to the base body, at least in part. The at least one conducting element includes at least one cermet. The electrical bushing further includes at least one metallic frame element, which fixes the base body in at least one housing opening of the housing.
摘要翻译：提出了用于可植入医疗装置的壳体中的电气套管。电气套管包括至少一个电绝缘基体和至少一个导电元件。导电元件通过基体设置在壳体的内部空间与外部空间之间的至少一个导电连接。导电元件至少部分地相对于基体气密地密封。至少一个导电元件包括至少一个金属陶瓷。电气衬套还包括至少一个金属框架元件，其将基体固定在壳体的至少一个壳体开口中。

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