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1. 发明申请

US20060173490A1 Filter system and method 审中-公开
标题翻译：过滤系统和方法
公开(公告)号：US20060173490A1
公开(公告)日：2006-08-03
申请号：US11049019
申请日：2005-02-01
申请人： Daniel Lafontaine , Mark Jenson , William Drasler
发明人： Daniel Lafontaine , Mark Jenson , William Drasler
IPC分类号： A61M29/00
CPC分类号： A61F2/2418 , A61F2/01 , A61F2/013 , A61F2/2433 , A61F2/958 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2210/0019 , A61F2220/005 , A61F2220/0066 , A61F2230/0006 , A61F2230/0069 , A61F2230/008
摘要： A filter system, comprising an elongate filter body defining a lumen and having a proximal end and a distal end. A valve can be provided defining a lumen and having a reversibly sealable opening for unidirectional flow of a fluid through the lumen. The valve can be adjoined proximal the distal end of the elongate filter body, wherein the elongate filter body filters the unidirectional flow of the fluid passing through the lumen of the valve and the lumen of the elongate filter body.
摘要翻译：一种过滤系统，包括限定内腔并具有近端和远端的细长过滤体。可以提供限定内腔的阀，并且具有可逆地密封的开口，用于流体通过内腔的单向流动。瓣膜可以在细长过滤体的远端附近邻接，其中细长的过滤器主体过滤通过阀的内腔和细长过滤体的内腔的单向流动。

2. 发明申请

US20060173475A1 Vascular catheter, system, and method 有权
标题翻译：血管导管，系统和方法
公开(公告)号：US20060173475A1
公开(公告)日：2006-08-03
申请号：US11049000
申请日：2005-02-01
申请人： Daniel Lafontaine , Mark Jenson , William Drasler
发明人： Daniel Lafontaine , Mark Jenson , William Drasler
IPC分类号： A61B17/22
CPC分类号： A61B17/32075 , A61B90/39 , A61B2017/00243 , A61B2017/22097 , A61F2/958
摘要： A catheter including an elongate body, a first cutting head and a second cutting head both having a blade, where the blades moves relative each other to provide a shearing action for cardiac tissue. The catheter can further include a stent positioned over an inflatable balloon, where the inflatable balloon can deploy the expandable stent over sheared cardiac tissue. The catheter can further be included in a system having a sheath, where at least a part of the catheter resides in the lumen of the sheath. The sheath further includes a cardiac valve and an expandable filter. The sheath can move relative the cardiac valve and the expandable filter to deploy the cardiac valve and at least a portion of the expandable filter proximal the inflatable balloon and the expandable stent.
摘要翻译：一种导管，其包括细长体，第一切割头和具有叶片的第二切割头，其中所述刀片相对于彼此移动以提供用于心脏组织的剪切动作。导管还可以包括定位在可膨胀气球上的支架，其中可充气球囊可以在可剪切的心脏组织上展开可扩张支架。导管可以进一步包括在具有护套的系统中，其中导管的至少一部分位于鞘的内腔中。护套还包括心脏瓣膜和可膨胀过滤器。护套可以相对于心脏瓣膜和可膨胀过滤器移动，以将心脏瓣膜部署，并且可扩张过滤器的至少一部分靠近可充气球囊和可扩张支架。

3. 发明申请

US20060047338A1 Cardiac valve, system, and method 有权
公开(公告)号：US20060047338A1
公开(公告)日：2006-03-02
申请号：US10933088
申请日：2004-09-02
申请人： Mark Jenson , William Drasler , Daniel Lafontaine
发明人： Mark Jenson , William Drasler , Daniel Lafontaine
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2230/008
摘要： A cardiac valve with a support frame having a first end member and a second end member opposing the first end member in a substantially fixed distance relationship, and a cover extending over the support frame to allow for unidirectional flow of a liquid through the valve.

4. 发明申请

US20050288695A1 Apparatus and method for treating occluded vasculature 有权
标题翻译：用于治疗闭塞性脉管系统的装置和方法
公开(公告)号：US20050288695A1
公开(公告)日：2005-12-29
申请号：US10877340
申请日：2004-06-24
申请人： Mark Jenson , William Drasler , Daniel Lafontaine
发明人： Mark Jenson , William Drasler , Daniel Lafontaine
IPC分类号： A61B17/00 , A61B17/22
CPC分类号： A61B17/3207 , A61B2017/00398 , A61B2017/22044 , A61B2017/22077
摘要： Occluded vasculature such as occluded arterial vasculature can be recanalized using a device that is configured to penetrate an occlusion, while limiting a distance that said penetration structure can extend in order to limit inadvertent vascular damage. The device can include an elongate sheath and a stylet disposed within the elongate sheath. The elongate sheath and the stylet can include, in combination, an engagement section that is configured to limit relative axial movement between the elongate sheath and the stylet.
摘要翻译：封闭的脉管系统如闭塞的动脉脉管系统可以使用被配置为穿透闭塞的装置再次通气，同时限制所述穿透结构可以延伸的距离，以限制无意的血管损伤。该装置可以包括细长护套和设置在细长护套内的探针。细长护套和探针可以组合地包括被配置为限制细长护套和探针之间的相对轴向运动的接合部分。

5. 发明申请

US20070150037A1 Leadless Cardiac Stimulation Systems 有权
标题翻译：无引导心脏刺激系统
公开(公告)号：US20070150037A1
公开(公告)日：2007-06-28
申请号：US11683577
申请日：2007-03-08
申请人： Roger Hastings , William Drasler , Daniel Lafontaine , Anupama Sadasiva , Scott Smith
发明人： Roger Hastings , William Drasler , Daniel Lafontaine , Anupama Sadasiva , Scott Smith
IPC分类号： A61N1/05
CPC分类号： A61N1/3756 , A61N1/0587 , A61N1/059 , A61N1/08 , A61N1/3627 , A61N1/365 , A61N1/37205 , A61N1/37217 , A61N1/37223 , A61N1/37229 , A61N1/37241 , A61N1/37288 , A61N1/375 , A61N1/3787
摘要： Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrodes that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Each of the electrodes contains a source of electrical energy for pacing the myocardium and is adapted to receive electromagnetic energy from a source outside the myocardium. The system also includes a source adapted for placement outside the myocardium and that uses locally measured electrocardiograms to synchronize pacing of the heart by sending electromagnetic commands to the electrodes to pace the myocardium surrounding the electrodes. Also disclosed is various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.
摘要翻译：提供了使用无引线电极来提供起搏治疗的各种构造的系统。在一个示例中，提供用于心脏心肌的多个部位的系统包括使用经皮，经腔，导管递送系统可植入位于心肌附近的位置的无线起搏电极。每个电极包含用于起搏心肌的电能源，并且适于从心肌外部的源接收电磁能。该系统还包括适于放置在心肌外部的源，并且使用局部测量的心电图来通过向电极发送电磁命令来同步心脏的起搏，以对电极周围的心肌进行加速。还公开了用于递送和植入电极组件的这种系统，无线电极组件和输送导管的各种配置。

6. 发明申请

US20070150038A1 Leadless Cardiac Stimulation Systems 有权
公开(公告)号：US20070150038A1
公开(公告)日：2007-06-28
申请号：US11683584
申请日：2007-03-08
申请人： Roger Hastings , William Drasler , Daniel Lafontaine , Anupama Sadasiva , Scott Smith
发明人： Roger Hastings , William Drasler , Daniel Lafontaine , Anupama Sadasiva , Scott Smith
IPC分类号： A61N1/05
CPC分类号： A61N1/3756 , A61N1/0587 , A61N1/059 , A61N1/08 , A61N1/3627 , A61N1/365 , A61N1/37205 , A61N1/37217 , A61N1/37223 , A61N1/37229 , A61N1/37241 , A61N1/37288 , A61N1/375 , A61N1/3787
摘要： Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrodes that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Each of the electrodes contains a source of electrical energy for pacing the myocardium and is adapted to receive electromagnetic energy from a source outside the myocardium. The system also includes a source adapted for placement outside the myocardium and that uses locally measured electrocardiograms to synchronize pacing of the heart by sending electromagnetic commands to the electrodes to pace the myocardium surrounding the electrodes. Also disclosed is various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.

7. 发明申请

US20070135883A1 Cardiac Stimulation system 审中-公开
标题翻译：心脏刺激系统
公开(公告)号：US20070135883A1
公开(公告)日：2007-06-14
申请号：US11549352
申请日：2006-10-13
申请人： William Drasler , Michael Pikus , Roger Hastings , Scott Smith , Martin Willard , Daniel Lafontaine , Douglas Saholt , Graig Kveen
发明人： William Drasler , Michael Pikus , Roger Hastings , Scott Smith , Martin Willard , Daniel Lafontaine , Douglas Saholt , Graig Kveen
IPC分类号： A61N1/05
CPC分类号： A61N1/059 , A61B5/0031 , A61B5/042 , A61B5/6848 , A61B5/6882 , A61N1/0573 , A61N1/3684 , A61N1/37205 , A61N1/3756
摘要： Some embodiments of pacing systems employ wireless electrode assemblies to provide pacing therapy. The wireless electrode assemblies may wirelessly receive energy via an inductive coupling so as to provide electrical stimulation to the surrounding heart tissue. In certain embodiments, the wireless electrode assembly may include one or more biased tines that shift from a first position to a second position to secure the wireless electrode assembly into the inner wall of the heart chamber.
摘要翻译：起搏系统的一些实施例采用无线电极组件来提供起搏治疗。无线电极组件可以通过电感耦合无线地接收能量，以便向周围的心脏组织提供电刺激。在某些实施例中，无线电极组件可以包括从第一位置移动到第二位置的一个或多个偏置尖齿，以将无线电极组件固定到心室的内壁。

8. 发明申请

US20060212027A1 Treating internal body tissue 有权
标题翻译：治疗内部身体组织
公开(公告)号：US20060212027A1
公开(公告)日：2006-09-21
申请号：US11082677
申请日：2005-03-17
申请人： Nassir Marrouche , Daniel Lafontaine
发明人： Nassir Marrouche , Daniel Lafontaine
IPC分类号： A61B18/02 , A61B18/04
CPC分类号： A61B18/02 , A61B18/04 , A61B2017/00243 , A61B2017/22069 , A61B2018/0022 , A61B2018/0212
摘要： Some embodiments of the invention relate to a system for treating tissue internal to a body, such as heart tissue. For example, the system may be used to ablate tissue as a treatment for atrial fibrillation. In certain embodiments, the system is capable of causing scar tissue to form in ostial areas of the atrium rather than inside the pulmonary vein. In such embodiments, the system may include a tissue treatment member that is operable to form an annular area of ablated tissue along the outer portion of the ostium in an area known as the antrum.
摘要翻译：本发明的一些实施方案涉及用于治疗身体内部的组织例如心脏组织的系统。例如，该系统可用于消融组织作为心房颤动的治疗。在某些实施方案中，该系统能够在心房的口部区域中形成瘢痕组织，而不是在肺静脉内部。在这样的实施例中，系统可以包括组织处理构件，其可操作以沿着称为窦的区域沿着口的外部部分形成消融组织的环形区域。

9. 发明申请

US20050257796A1 Percutaneous myocardial revascularization 失效
标题翻译：经皮心肌血运重建
公开(公告)号：US20050257796A1
公开(公告)日：2005-11-24
申请号：US11191056
申请日：2005-07-28
申请人： Louis Ellis , Daniel Lafontaine , Roger Hastings , Lauri DeVore
发明人： Louis Ellis , Daniel Lafontaine , Roger Hastings , Lauri DeVore
IPC分类号： A61B19/00 , A61B6/00 , A61B17/00 , A61B17/22 , A61B17/32 , A61B17/34 , A61B18/00 , A61B18/02 , A61B18/12 , A61B18/14 , A61B18/18
CPC分类号： A61B17/3207 , A61B18/1492 , A61B90/39 , A61B2017/00247 , A61B2017/22077 , A61B2017/3488 , A61B2018/00273 , A61B2018/00291 , A61B2018/00392 , A61B2018/144 , A61B2090/395 , A61M2210/125
摘要： Devices and methods for creating a series of percutaneous myocardial revascularization (PMR) channels in the heart. One method includes forming a pattern of channels in the myocardium leading from healthy tissue to hibernating tissue. Suitable channel patterns include lines and arrays. One method includes anchoring a radiopaque marker to a position in the ventricle wall, then using fluoroscopy repeatedly to guide positioning of a cutting tip in the formation of multiple channels. Another method uses radiopaque material injected into each channel formed, as a marker. Yet another method utilizes an anchorable, rotatable cutting probe for channel formation about an anchor member, where the cutting probe can vary in radial distance from the anchor. Still another method utilizes a multiple wire radio frequency burning probe, for formation of multiple channels simultaneously. Still another method utilizes liquid nitrogen to cause localized tissue death.
摘要翻译：在心脏中创建一系列经皮心肌血运重建（PMR）通道的装置和方法。一种方法包括在从健康组织导向冬眠组织的心肌中形成通道图案。合适的渠道模式包括线和阵列。一种方法包括将不透射线标记物固定在心室壁中的位置，然后重复使用荧光透视来引导切割尖端在形成多个通道中的定位。另一种方法使用注射到形成的每个通道中的不透射线材料作为标记。另一种方法利用可锚定的，可旋转的切割探针，用于围绕锚定构件的通道形成，其中切割探针可以与锚固件的径向距离变化。另一种方法是利用多线射频燃烧探头，同时形成多个通道。另一种方法利用液氮引起局部组织死亡。

10. 发明授权

US08282599B2 Therapeutic catheter with displacement sensing transducer 有权
标题翻译：带位移传感器的治疗导管
公开(公告)号：US08282599B2
公开(公告)日：2012-10-09
申请号：US11941472
申请日：2007-11-16
申请人： Alan Eskuri , Daniel Lafontaine
发明人： Alan Eskuri , Daniel Lafontaine
IPC分类号： A61M25/095
CPC分类号： A61B5/00 , A61B5/061 , A61B5/6848 , A61B8/12 , A61B17/3478 , A61B18/24 , A61B2017/0003 , A61B2017/00247 , A61B2018/00392 , A61B2090/062 , A61B2090/0811 , A61M5/46 , A61M25/0084
摘要： A catheter device having a proboscis, such as a needle, and a transducer which detects the axial displacement of the proboscis in relation to the distal tip of the catheter. The transducer is positioned at a distal portion of the catheter and may comprise an induction coil or a potentiometer. Axial displacement of the proboscis changes the amount of inductance or resistance in the transducer. This change in inductance or resistance can be calibrated to the amount of axial displacement of the proboscis and provided as feedback to the user.
摘要翻译：具有诸如针的长鼻子的导管装置和检测长鼻相对于导管的远端的轴向位移的换能器。换能器定位在导管的远端部分，并且可以包括感应线圈或电位计。长鼻子的轴向位移会改变传感器的电感或电阻。电感或电阻的这种变化可以校准到长鼻子的轴向位移量，并作为反馈提供给用户。

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