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    • 4. 发明申请
    • APPARATUS AND METHOD FOR MULTI-MODAL IMAGING
    • 多模式成像的装置和方法
    • US20100220836A1
    • 2010-09-02
    • US12763231
    • 2010-04-20
    • Gilbert D. FekeWilliam E. McLaughlinDouglas L. Vizard
    • Gilbert D. FekeWilliam E. McLaughlinDouglas L. Vizard
    • G01N23/04H04N5/225G06K9/00
    • A61B6/4417A61B5/0035A61B5/0059A61B5/0071A61B6/00A61B6/5247A61B2562/17
    • An imaging system and method for imaging an immobilized object. The imaging system includes a support member adapted to receive the object in an immobilized state. The system also includes first means for imaging the immobilized object in a first imaging mode to capture a first image, and second means for imaging the immobilized object in a second imaging mode to capture a second image. The first imaging mode is selected from the group: x-ray mode and radio isotopic mode. The second imaging mode is selected from the group: bright-field mode and dark-field mode. The first and second means for imaging may be included in a capture system having a camera, a first mirror on a first side of the support member for reflecting light to capture the first and second images and a second mirror on a second, opposite side of the support member for reflecting light to capture a third image from an opposite side of the object. A movable phosphor screen is employed when the first image is captured and not employed when the second image is captured. The phosphor screen is adapted to be movable without moving the immobilized object and support member. The system can further include means for generating a third image comprised of the first and second images.
    • 一种用于对固定物体进行成像的成像系统和方法。 成像系统包括适于在固定状态下接收物体的支撑构件。 该系统还包括用于在第一成像模式下成像固定的物体以捕获第一图像的第一装置,以及用于在第二成像模式下成像固定的物体以捕获第二图像的第二装置。 第一种成像模式选自x射线模式和放射同位素模式。 第二种成像模式选自明场模式和暗场模式。 用于成像的第一和第二装置可以包括在具有照相机的捕获系统中,在支撑构件的第一侧上的第一反射镜用于反射光以捕获第一和第二图像,并且在第二反射镜的第二相对侧 用于反射光以从物体的相对侧捕获第三图像的支撑构件。 当捕获第一图像时采用可移动荧光屏,并且当捕获第二图像时不采用可移动荧光屏。 荧光屏适于可移动而不移动固定的物体和支撑构件。 该系统还可以包括用于生成由第一和第二图像组成的第三图像的装置。
    • 5. 发明申请
    • TUNABLE SPECTRAL FILTRATION DEVICE
    • 可调光谱过滤装置
    • US20100208348A1
    • 2010-08-19
    • US12709156
    • 2010-02-19
    • Gilbert D. FekeDouglas L. Vizard
    • Gilbert D. FekeDouglas L. Vizard
    • G02B5/28G02B5/22
    • A61B5/0059A61B6/00
    • A tunable spectral filtration device comprises at least one optical filter for intersecting a first path of converging or diverging light comprising an axis at a first angle of incidence and at least one device positioned to enable a second path of the converging or diverging light to pass through the at least one optical filter at a second angle of incidence. The optical filter comprises at least one coating and is tiltable over a plurality of angles with respect to the axis. The first angle of incidence is opposite in sign to the second angle of incidence, such that the positioning of the at least one optical filter and the at least one device substantially cancels angle-of-incidence dependent spectral broadening and/or polarization dependent spectral broadening of the converging or diverging light.
    • 可调谐光谱过滤装置包括至少一个光学滤光器,用于与会聚或发散光的第一路径交叉,该第一路径包括第一入射角的轴线和至少一个装置,其定位成使得会聚或发散光的第二路径能够通过 所述至少一个滤光器处于第二入射角。 光学滤波器包括至少一个涂层并且可相对于轴线在多个角度上倾斜。 第一入射角与第二入射角相反,使得至少一个滤光器和至少一个器件的定位基本上抵消入射角依赖的光谱展宽和/或偏振相关光谱展宽 的会聚光或发散光。
    • 6. 发明授权
    • Method and apparatus for examining optic nerve head circulation
    • US5830147A
    • 1998-11-03
    • US866539
    • 1997-05-30
    • Gilbert T. FekeGilbert D. Feke
    • Gilbert T. FekeGilbert D. Feke
    • A61B3/12A61B5/02
    • A61B3/1233
    • A laser source attached to an ophthalmic observation instrument, such as a fundus camera, projects a spot, and a light collector is positioned in the image field of the instrument over the spot to collect return light scattered from a homogeneous tissue bed in the image field. The collected light is directed onto a photomultiplier and digitized at a sampling rate above several kHz to provide a continuous data stream which is fed to a process/control module that operates to automatically define a number n of sample intervals, select a subset of the sample intervals for analysis, transform the selected intervals, and evaluate the shape of the transformed sample intervals. The process/control module may be implemented on a simple computer, and include a user interface which indicates status of signal acquisition, selection and evaluation during a short, e.g., one-minute illumination interval. The ophthalmic instrument images tissue of the fundus, and the light collector is configured to collect light from a target region having a diameter under 0.5 mm, preferably under 0.2 mm, and as little as 0.02 mm which is selected by the operator by moving the light collector to a region of the image field which corresponds to the illumination spot, and is free of vessels. The control/analysis module also receives patient data via keyboard or network communication, and merges patient data with the acquired spectra to form medical records. Preferably, it also accesses or files records for the same patient in storage. A number of threshold, evaluation or diagnostic routines are implemented as macros to highlight or annotate the transformed measurement spectra and display the annotated data. The module is set to carry out signal acquisition for no more than a fixed number n of one-second intervals, and to terminate acquisition earlier if it has evaluated and positively approved a second, lesser fixed number m of well-formed signal traces. Audible prompts indicate acquisition of proper traces, and completion of analysis or fitting steps. A printer may print out spectra and derived data with user-entered annotations.
    • 7. 发明申请
    • APPARATUS AND METHOD FOR MULTI-MODAL IMAGING USING MULTIPLE X-RAY SOURCES
    • 使用多个X射线源进行多模式成像的装置和方法
    • US20120106702A1
    • 2012-05-03
    • US13305919
    • 2011-11-29
    • Gilbert D. Feke
    • Gilbert D. Feke
    • G01N23/04
    • A61B5/0059A61B6/00A61B6/4417A61B6/5235A61B6/5247
    • An imaging system for imaging at least a first and a second subject has a support stage to support the subjects. An imaging system has an ionizing radiation imaging section with at least a first ionizing radiation source for directing ionizing radiation within a first zone that includes the first subject and a second ionizing radiation source for directing ionizing radiation within a second zone that lies substantially outside the first zone and that includes the second subject. At least one imaging receiver forms an image of the subject within each zone. A camera system obtains at least one image of the at least first and second subjects. A computer is in signal communication with the imaging system and energizable to form a combined image from two or more images of the same subjects.
    • 用于对至少第一和第二对象进行成像的成像系统具有支持对象的支持阶段。 成像系统具有电离辐射成像部分,其具有至少第一电离辐射源,用于在包括第一受试者的第一区域内引导电离辐射,以及第二电离辐射源,用于将电离辐射引导到基本上位于第一 并包括第二个主题。 至少一个成像接收器在每个区域内形成对象的图像。 相机系统获得至少第一和第二主体的至少一个图像。 计算机与成像系统进行信号通信并且能够激活以形成来自相同被摄体的两个或多个图像的组合图像。
    • 9. 发明授权
    • Imaging enclosure apparatus and methods
    • 成像外壳设备和方法
    • US08724979B2
    • 2014-05-13
    • US13757892
    • 2013-02-04
    • Gilbert D. Feke
    • Gilbert D. Feke
    • G03B15/02
    • G03B15/06G01N21/6456
    • An imaging apparatus for imaging an object has an enclosure chassis that defines an enclosed imaging volume and that provides an imaging aperture to a camera apparatus that mounts against the chassis and that further provides at least a first lateral access opening for access to the object. A light-obstructing gasket is coupled to the enclosure chassis and has at least a first foldable lateral access leaf that folds to a first position against the first lateral access opening to block ambient light through the first lateral access opening and that folds away from the first lateral access opening to a second position to allow access to the object.
    • 用于对物体成像的成像装置具有限定封闭成像体积并且向相对于底架安装的相机装置提供成像孔的外壳底架,并且进一步提供用于接近物体的至少第一横向进入开口。 遮光垫圈联接到外壳底盘并且具有至少第一可折叠侧向进入叶片,其折叠到第一位置以抵靠第一横向进入开口,以阻挡通过第一横向进入开口的环境光,并且折叠远离第一 横向进入开口到第二位置以允许接近物体。