专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20130121918A1 Nano-Hybrid Delivery System for Sequential Utilization of Passive and Active Targeting 有权
标题翻译：用于顺序利用被动和主动定位的纳米混合交付系统
公开(公告)号：US20130121918A1
公开(公告)日：2013-05-16
申请号：US13642868
申请日：2011-04-20
申请人： Seungpyo Hong , Ying Liu
发明人： Seungpyo Hong , Ying Liu
IPC分类号： A61K9/127 , A61K9/14
CPC分类号： A61K9/127 , A61K9/1273 , A61K9/14 , A61K9/146 , A61K9/5153
摘要： The present invention features nanohybrid drug delivery composition which combines both passive and active targeting for the prevention and treatment of disease. The composition is shell-encapsulated multivalent polymeric scaffold with a therapeutic agent and targeting agent attached thereto.
摘要翻译：本发明的特征在于纳米杂交药物递送组合物，其组合用于预防和治疗疾病的被动和主动靶向。该组合物是具有与其连接的治疗剂和靶向剂的壳包封的多价聚合物支架。

2. 发明授权

US09212258B2 Amphiphilic dendron-coils, micelles thereof and uses 有权
标题翻译：两亲性树突状线圈，胶束和用途
公开(公告)号：US09212258B2
公开(公告)日：2015-12-15
申请号：US14001115
申请日：2012-02-22
申请人： Seungpyo Hong , Jin Woo Bae
发明人： Seungpyo Hong , Jin Woo Bae
IPC分类号： C08G63/91 , A61K9/50 , C12Q1/02 , A61K9/107 , A61K47/44 , C08G63/66 , G01N33/574 , A61K31/352 , A61K31/405 , C08G81/00 , C08G83/00
CPC分类号： A61K9/1075 , A61K9/5031 , A61K31/352 , A61K31/405 , A61K47/10 , A61K47/34 , A61K47/44 , C08G63/66 , C08G63/912 , C08G81/00 , C08G83/003 , C08G83/004 , C08G83/008 , C12Q1/02 , G01N33/574
摘要： The invention generally relates to the fields of drug delivery and cell capture. In particular, the invention relates to amphiphilic dendron-coils, micelles thereof and their use for drug delivery vehicles and/or cell capture.
摘要翻译：本发明一般涉及药物递送和细胞捕获的领域。特别地，本发明涉及两亲性树突状线圈，其胶束及其用于药物递送载体和/或细胞捕获的用途。

3. 发明授权

US08986988B2 Cell rolling separation 有权
标题翻译：电解槽分离
公开(公告)号：US08986988B2
公开(公告)日：2015-03-24
申请号：US12680249
申请日：2008-09-29
申请人： Rohit Nandkumar Karnik , Seungpyo Hong , Ying Mei , Daniel Griffith Anderson , Jeffrey Michael Karp , Robert S. Langer , Suman Bose
发明人： Rohit Nandkumar Karnik , Seungpyo Hong , Ying Mei , Daniel Griffith Anderson , Jeffrey Michael Karp , Robert S. Langer , Suman Bose
IPC分类号： C12N5/07 , C12N5/00 , C12N5/0735 , C12N5/078 , C12M1/00
CPC分类号： C12N5/0068 , B01L3/502715 , B01L3/502761 , B01L2200/0647 , B01L2300/0877 , B01L2300/16 , C12M23/16 , C12M47/02 , C12N5/0062 , C12N2501/58 , C12N2501/585 , C12N2533/50 , C12N2533/52 , C12N2535/10
摘要： The present invention provides systems for cell separation based on cell rolling on surfaces along edges of regions coated with cell adhesion molecules. A variety of designs of coated regions and edges are disclosed.
摘要翻译：本发明提供了基于在细胞粘附分子包被的区域的边缘上的表面上的细胞滚动的细胞分离系统。公开了涂覆区域和边缘的各种设计。

4. 发明授权

US08493636B2 Motion tracking method using scanning device 有权
标题翻译：运动跟踪方法采用扫描装置
公开(公告)号：US08493636B2
公开(公告)日：2013-07-23
申请号：US13123084
申请日：2008-11-21
申请人： Jinwook Kim , Seungpyo Hong , Heedong Ko
发明人： Jinwook Kim , Seungpyo Hong , Heedong Ko
IPC分类号： H04N1/04
CPC分类号： G01S17/66
摘要： The motion tracking method disclosed herein suggests a method for precisely tracking the motion of a scanning device by correcting the surrounding information distortedly recognized due to the time differences between pieces of information regarding the surroundings of the device over one scanning cycle. The method, as a motion tracking method of a scanning device collecting the surrounding information corresponding to a plurality of the points of the surroundings, includes collecting the surrounding information, obtaining the displacement data of the scanning device using the surrounding information, updating the velocity of the scanning device using the displacement data of the scanning device, correcting the surrounding information using the updated velocity of the scanning device, and determining location and position information of the scanning device using the corrected surrounding information. According to the method herein, the motion of the scanning device may be more precisely tracked because the surrounding information is corrected based on the velocity of the scanning device.
摘要翻译：本文公开的运动跟踪方法提出了一种通过校正由于在一个扫描周期上与设备的周围环境相关的信息之间的时间差异而失真识别的周围信息来精确跟踪扫描设备的运动的方法。作为收集与周围的多个点对应的周围信息的扫描装置的运动跟踪方法，包括收集周围信息，使用周围信息获取扫描装置的位移数据，更新速度所述扫描装置使用所述扫描装置的位移数据，使用所述扫描装置的更新速度来校正所述周围信息，以及使用所述校正的周围信息来确定所述扫描装置的位置和位置信息。根据本文的方法，可以更精确地跟踪扫描装置的运动，因为基于扫描装置的速度来校正周围的信息。

5. 发明申请

US20120077246A1 Methods and Devices for Capturing Circulating Tumor Cells 审中-公开
标题翻译：捕获循环肿瘤细胞的方法和装置
公开(公告)号：US20120077246A1
公开(公告)日：2012-03-29
申请号：US13265916
申请日：2010-04-23
申请人： Seungpyo Hong , David Eddington , Ja Hye Myung , Cari Launiere
发明人： Seungpyo Hong , David Eddington , Ja Hye Myung , Cari Launiere
IPC分类号： C12N11/00 , B01L3/00
CPC分类号： G01N33/574
摘要： A method of capturing a Circulating Tumor Cell (CTC) from a sample includes introducing a sample into a microfluidic device having a cell capture surface and a flow modification surface under conditions that allow a CTC to bind to a cell rolling-inducing agent and a capturing agent disposed on the cell capture surface. The flow modification surface induces a rotational flow within the sample as it flows through the microfluidic device.
摘要翻译：从样品捕获循环肿瘤细胞（CTC）的方法包括将样品引入到具有细胞捕获表面和流动修饰表面的微流体装置中，该条件允许CTC结合细胞转导诱导剂和捕获药剂置于细胞捕获表面上。流动修饰表面在样品流过微流体装置时会引起样品内的旋转流动。

6. 发明申请

US20180164562A1 CONFOCAL MICROSCOPY SYSTEM WITH VARI-FOCUS OPTICAL ELEMENT 审中-公开
公开(公告)号：US20180164562A1
公开(公告)日：2018-06-14
申请号：US15333188
申请日：2016-10-25
申请人： JINA BYEON , KI BOK KIM , SEUNGPYO HONG , GYOUNG IL CHO , JIN YOUNG SOHN , CHEONG SOO SEO
发明人： JINA BYEON , KI BOK KIM , SEUNGPYO HONG , GYOUNG IL CHO , JIN YOUNG SOHN , CHEONG SOO SEO
IPC分类号： G02B21/00 , G02B21/02 , G02B21/06
CPC分类号： G02B21/006 , G02B21/0032 , G02B21/0048 , G02B21/008 , G02B21/025 , G02B21/06
摘要： The present invention utilizes aperture array element and vari-focus optical element in confocal microscopy system. With the aperture array element lateral scanning property can be obtained and with vari-focus optical element axial scanning property can be obtained. Especially Micromirror Array Lens is used as a vari-focus optical element, fast and extended depth of focus scan range can be obtained. Thus the present invention of confocal microscopy with the vari-focus optical element increases scan speed of confocal microscopy system. The confocal microscopy system of the present invention comprises an illumination source, an aperture array element, a vari-focus optical element, an objective lens element, a photosensitive optical sensor device. With these elements, confocal microscopy is performed to get three dimensional images. Three dimensional with the confocal microscopy of the present invention can be obtained three dimensional images: two dimensional lateral images can be obtained with aperture array element scanning laterally with multiple aperture to increase scanning speed and the depth information of each pixel in two dimensional image can be determined by the vari-focus optical element. Thus three dimensional images can be reconstructed by the two dimensional imaged obtained from lateral scan and depth information from the axial scan. The present invention of the confocal microscopy system improves slow speed of the confocal system with considerable amount by use of fast varying vari-focus optical element and fast scanning aperture array element.

7. 发明申请

US20140147056A1 DEPTH IMAGE NOISE REMOVAL APPARATUS AND METHOD BASED ON CAMERA POSE 有权
标题翻译：深度图像噪声去除装置和基于摄像机的方法
公开(公告)号：US20140147056A1
公开(公告)日：2014-05-29
申请号：US13746808
申请日：2013-01-22
申请人： Jinwook KIM , Seungpyo HONG
发明人： Jinwook KIM , Seungpyo HONG
IPC分类号： G06T5/00
CPC分类号： G06T5/002 , G06T5/50 , G06T2207/10028
摘要： Disclosed are a depth image noise removal apparatus based on a camera pose, which includes: a depth image obtaining unit for obtaining a plurality of depth images; a camera pose converting unit for converting camera poses of the plurality of depth images into a camera pose of a reference depth image; and a depth image filtering unit for filtering the reference depth image by using a weighted average of each pixel of the reference depth image, and a method using this apparatus.
摘要翻译：公开了一种基于相机姿态的深度图像噪声去除装置，其包括：深度图像获取单元，用于获得多个深度图像; 照相机姿态转换单元，用于将多个深度图像的摄像机姿态转换为参考深度图像的相机姿态; 以及深度图像滤波单元，其使用参考深度图像的每个像素的加权平均值来对参考深度图像进行滤波，以及使用该装置的方法。

8. 发明申请

US20140037747A1 AMPHIPHILIC DENDRON-COILS, MICELLES THEREOF AND USES 有权
标题翻译： AMPHIPHILIC DENDRON-COILS，MICELLES THEREOF AND USES
公开(公告)号：US20140037747A1
公开(公告)日：2014-02-06
申请号：US14001115
申请日：2012-02-22
申请人： Seungpyo Hong , Jin Woo Bae
发明人： Seungpyo Hong , Jin Woo Bae
IPC分类号： C08G63/91 , A61K9/50 , C12Q1/02
CPC分类号： A61K9/1075 , A61K9/5031 , A61K31/352 , A61K31/405 , A61K47/10 , A61K47/34 , A61K47/44 , C08G63/66 , C08G63/912 , C08G81/00 , C08G83/003 , C08G83/004 , C08G83/008 , C12Q1/02 , G01N33/574
摘要： The invention generally relates to the fields of drug delivery and cell capture. In particular, the invention relates to amphiphilic dendron-coils, micelles thereof and their use for drug delivery vehicles and/or cell capture.
摘要翻译：本发明一般涉及药物递送和细胞捕获的领域。特别地，本发明涉及两亲性树突状线圈，其胶束及其用于药物递送载体和/或细胞捕获的用途。

9. 发明申请

US20110194158A1 MOTION TRACKING METHOD USING SCANNING DEVICE 有权
标题翻译：使用扫描设备的运动跟踪方法
公开(公告)号：US20110194158A1
公开(公告)日：2011-08-11
申请号：US13123084
申请日：2008-11-21
申请人： Jinwook Kim , Seungpyo Hong , Heedong Ko
发明人： Jinwook Kim , Seungpyo Hong , Heedong Ko
IPC分类号： H04N1/04
CPC分类号： G01S17/66
摘要： The motion tracking method disclosed herein suggests a method for precisely tracking the motion of a scanning device by correcting the surrounding information distortedly recognized due to the time differences between pieces of information regarding the surroundings of the device over one scanning cycle. The method, as a motion tracking method of a scanning device collecting the surrounding information corresponding to a plurality of the points of the surroundings, includes collecting the surrounding information, obtaining the displacement data of the scanning device using the surrounding information, updating the velocity of the scanning device using the displacement data of the scanning device, correcting the surrounding information using the updated velocity of the scanning device, and determining location and position information of the scanning device using the corrected surrounding information. According to the method herein, the motion of the scanning device may be more precisely tracked because the surrounding information is corrected based on the velocity of the scanning device.
摘要翻译：本文公开的运动跟踪方法提出了一种通过校正由于在一个扫描周期上与设备的周围环境相关的信息之间的时间差异而失真识别的周围信息来精确跟踪扫描设备的运动的方法。作为收集与周围的多个点对应的周围信息的扫描装置的运动跟踪方法，包括收集周围信息，使用周围信息获取扫描装置的位移数据，更新速度所述扫描装置使用所述扫描装置的位移数据，使用所述扫描装置的更新速度来校正所述周围信息，以及使用所述校正的周围信息来确定所述扫描装置的位置和位置信息。根据本文的方法，可以更精确地跟踪扫描装置的运动，因为基于扫描装置的速度来校正周围的信息。

10. 发明申请

US20190175754A1 METHODS FOR TREATING SUBJECTS SUFFERING FROM ACUTE MYELOID LEUKEMIA WITH FLT3 LIGAND-TARGETED MIR-150 NANOPARTICLES 审中-公开
公开(公告)号：US20190175754A1
公开(公告)日：2019-06-13
申请号：US16310104
申请日：2017-06-14
申请人： Jianjun CHEN , Seungpyo HONG , Xi JIANG , Zejuan LI
发明人： Jianjun CHEN , Seungpyo HONG , Xi JIANG , Zejuan LI
IPC分类号： A61K47/69 , A61P35/02 , A61K31/551 , C12N15/113 , A61K31/7105
摘要： A nanoparticle delivery system designed for sustained delivery of microRNA-150 (miR-150) to FLT3-overexpressing acute myeloid leukemia (AML) cells, the delivery system comprising poly(amidoamine) (PAMAM) dendrimers complexed with miR-150, wherein at least one dendrimer is surface-functionalized with a ligand specific for FLT3 receptor, and methods for treating AML characterized by FLT3-overexpression are provided.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式