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1. 发明公开

KR1020060037035A 참꽃창포 추출물을 함유하는 피부 미백용 화장료 无效
标题翻译：含有IRIS ENSATA VAR的皮肤白化提取物的化妆品组合物。 SPONTANEA
公开(公告)号：KR1020060037035A
公开(公告)日：2006-05-03
申请号：KR1020040086143
申请日：2004-10-27
申请人： 주식회사 아모레퍼시픽그룹
发明人： 이소현 , 김한성 , 최현정 , 이정아 , 이병곤 , 장이섭
IPC分类号： A61K8/97 , A61Q19/02
摘要： 본 발명은 피부 미백용 화장료에 관한 것으로서, 본 발명에 따른 피부 미백용 화장료는 참꽃창포 추출물을 유효성분으로 함유하는 것을 특징으로 한다. 본 발명에 의한 참꽃창포 추출물을 함유하는 화장료는 피부에 대한 부작용이 없어 안전하게 사용될 수 있을 뿐만 아니라 멜라닌 생성을 억제하여 색소 침착을 저해하는 효과가 뛰어나므로 이를 유효성분으로 함유하는 화장료는 기미나 주근깨 개선 및 피부미백에 효과적으로 사용될 수 있다.
참꽃창포, 미백, 화장료, 색소침착 저해, 주근깨 개선

2. 发明授权

KR100543122B1 유자 추출물을 함유하는 피부 외용제 조성물 有权
标题翻译：用于外用于含有柚子水果提取物的皮肤的组合物
公开(公告)号：KR100543122B1
公开(公告)日：2006-01-20
申请号：KR1020020077791
申请日：2002-12-09
申请人： 주식회사 아모레퍼시픽그룹
发明人： 김지현 , 강승현 , 안수미 , 이종찬 , 이병곤
IPC分类号： A61K36/14 , A61P17/00 , A61P17/02
摘要： 본 발명은 유자(
Citrus junos ) 추출물을 함유하는 피부 외용제 조성물에 관한 것으로, 더욱 상세하게는 유자 추출물, 특히 발효 유자 추출물을 함유함으로써 지방세포의 피하 지방 분해 효과, 셀룰라이트의 제거 효과 및 탄력 증진 효과가 뛰어난 피부 외용제 조성물에 관한 것이다.
유자추출물*발효*지방세포*지방분해*중성지방*유리지방산*글리세롤*셀룰라이트

3. 发明公开

KR1020040092538A 녹차 성분을 함유하는 피부 외용제 조성물 有权
标题翻译：组合物外用于含有CAMENIA SINENSIS的活性成分的皮肤，以分解脂肪和去除细胞因子
公开(公告)号：KR1020040092538A
公开(公告)日：2004-11-04
申请号：KR1020030026015
申请日：2003-04-24
申请人： 주식회사 아모레퍼시픽그룹
发明人： 김지현 , 안수미 , 이종찬 , 김영경 , 이병곤
IPC分类号： A61K31/353 , A61P3/04
CPC分类号： A61K8/44 , A61K8/498 , A61K8/97 , A61K2800/72 , A61Q19/06
摘要： PURPOSE: Provided is a composition for external application to skin containing active ingredients of Camellia sinensis. The composition decomposes fat and suppresses obesity excellently by decomposing subcutaneous fat and removing cellulase. CONSTITUTION: The composition for the decomposition of fat in a cell is characterized by containing, based on the total weight of the composition, 0.0001-20 wt.% of at least one selected from the group consisting of theanine and catechin as an active ingredient. Therefore, the composition facilitates the decomposition of neutral fat in a cell. The theanine and catechin are extracted from Camellia sinensis.
摘要翻译：目的：提供外用皮肤含有山茶花活性成分的组合物。该组合物分解脂肪，通过分解皮下脂肪和去除纤维素酶，优异地抑制肥胖。构成：细胞中脂肪分解的组合物的特征在于，以组合物的总重量计含有0.0001-20重量％的选自茶氨酸和儿茶素作为活性成分的至少一种。因此，该组合物促进细胞中中性脂肪的分解。茶氨酸和儿茶素从山茶提取物。

4. 发明授权

KR100444102B1 백자인 추출물 함유 발모촉진용 화장료 조성물 有权
标题翻译： 백자인추출물함유발모촉진용화장료조성물
公开(公告)号：KR100444102B1
公开(公告)日：2004-08-11
申请号：KR1020010082716
申请日：2001-12-21
申请人： 주식회사 아모레퍼시픽그룹
发明人： 박원석 , 이창훈 , 손의동 , 남개원 , 김수현 , 이병곤
IPC分类号： A61K8/97 , A61Q7/00
摘要： PURPOSE: A cosmetic composition containing a Thujae Semen extract which includes a large amount of active material capable of effectively inhibiting alopecia-inducing 5alpha-reductase by converting testosterone to dihydrotestosterone is provided. Therefore, the composition can be effectively used as a cosmetic for promoting hair growth and treating alopecia. CONSTITUTION: A cosmetic composition contains 0.0001 to 5% by weight of a Thujae Semen extract as an active ingredient, based on the dried weight of the composition. Thujae Semen is extracted in a organic solvent selected from C1-4 anhydrous or hydrous lower alcohol, hexane, ethylacetate or ethylether in an extractor with a cooling condenser at 50 to 10deg.C for 1 to 10hr and then distilled under reduced pressure in a distillation apparatus with a cooling condenser. For an example, 1.0% by weight of a Thujae Semen extract is mixed with 55.0% by weight of ethanol, 5.0% by weight of castor oil, 3.0% by weight of glycerine, 0.1% by weight of piroctone olamine, a suitable amount of a fragrance, pigment and the balance of water to produce a hair tonic preparation.
摘要翻译：目的：提供了含有大量活性物质的Thujae精子提取物的化妆品组合物，所述活性物质能够通过将睾酮转化为二氢睾酮而有效抑制引起脱发的5α-还原酶。因此，该组合物可以有效地用作促进毛发生长和治疗脱发的化妆品。组成：基于组合物的干重，化妆品组合物含有0.0001至5重量％的Thujae精子提取物作为活性成分。 Thujae精液在选自C1-4无水或含水低级醇，己烷，乙酸乙酯或乙醚的有机溶剂中，在带有冷却冷凝器的萃取器中在50至10℃下萃取1至10小时，然后在减压下蒸馏带有冷凝器的设备。例如，将1.0重量％的Thujae精子提取物与55.0重量％的乙醇，5.0重量％的蓖麻油，3.0重量％的甘油，0.1重量％的吡罗克酮乙醇胺，适量的香料，颜料和余量的水以产生生发剂。

5. 发明授权

KR100407640B1 신규한 디페닐 아미드 유도체, 그의 제조방법 및 이를포함하는 약학 및 화장료 조성물 失效
标题翻译： 신규한디페닐아미드유도체，그의제조방법및이를포함하는약학및화장료조성물
公开(公告)号：KR100407640B1
公开(公告)日：2003-12-01
申请号：KR1020000078490
申请日：2000-12-19
申请人： 김선여 , 최상윤 , 석경호 , 김상희 , 김호철 , 주식회사 아모레퍼시픽그룹
发明人： 김선여 , 김상희 , 최상윤 , 김호철 , 석경호 , 황재성 , 이병곤
IPC分类号： C07C233/88
摘要： PURPOSE: Provided are novel diphenyl amide derivatives which have tyrosinase inhibiting and lightening effects, a production method thereof, and a pharmaceutical and cosmetic composition containing the same. CONSTITUTION: The diphenyl amide derivatives have a chemical structure represented by the formula I, in which R1 to R5 are independently hydrogen, halogen, C1-4 alkyl, C3-6 cycloalkyl or C1-4 alkoxy, R6 to R10 are independently hydrogen or C1-4 alkoxy, and R11 is hydrogen, C1-4 alkyl, C3-6 cycloalkyl or C1-4 alkoxy. The diphenyl amide derivatives are prepared by reacting a compound of formula II with triphenylphosphine in the presence of trihaloacetonitrile to obtain a compound of formula III, and reacting the compound of formula III with a compound of formula IV in a polar solvent using tertiary amine as a catalyst. In the formulae III and IV, x is a halogen atom and R1 to R11 are the same as defined above.
摘要翻译：目的：提供具有酪氨酸酶抑制和增亮作用的新型二苯基酰胺衍生物及其生产方法，以及含有其的药物和化妆品组合物。构成：二苯基酰胺衍生物具有由式I表示的化学结构，其中R1至R5独立地为氢，卤素，C1-4烷基，C3-6环烷基或C1-4烷氧基，R6至R10独立地为氢或C1 -4烷氧基，并且R 11是氢，C 1-4烷基，C 3-6环烷基或C 1-4烷氧基。二苯基酰胺衍生物通过使式II化合物与三苯基膦在三卤乙腈存在下反应得到式III化合物，并使式III化合物与式IV化合物在极性溶剂中反应，使用叔胺作为催化剂。在式III和IV中，x是卤素原子，并且R1至R11与以上定义的相同。

6. 发明授权

KR100406125B1 토릴린을 함유하는 피부 외용제 조성물 失效
标题翻译： 토릴린을함유하하는피부외용제조성토
公开(公告)号：KR100406125B1
公开(公告)日：2003-11-14
申请号：KR1020010064002
申请日：2001-10-17
申请人： 주식회사 아모레퍼시픽그룹
发明人： 이창훈 , 박원석 , 손의동 , 남개원 , 김수현 , 이병곤
IPC分类号： A61K8/37 , A61Q7/00
摘要： PURPOSE: Provided is a composition of a dermatological agent containing torilin which is extracted from Torilis japonica (Houtt.) DC. having an excellent inhibition effect on 5α-reductase and a promotion effect on hair growth. Therefore it has depletion-preventing effect and hair growing effect. CONSTITUTION: The composition of a dermatological agent contains 0.0001 to 5% by weight of torilin represented by the formula(1). Torilis japonica (Houtt.) DC. is extracted by heating at 50 to 100deg.C for 1 to 10hr with 3 to 5 times of an organic solvent such as lower alcohol, ethylacetate, hexane or diethylether, or soaking in the above solvent at 0 to 40deg.C for 1 to 30 days. The extract is thoroughly dried with a vacuum drier.
摘要翻译：用途：提供一种含有从Torilis japonica（Houtt。）DC提取的含有torilin的皮肤病药剂的组合物。对5α-还原酶具有优异的抑制作用和对毛发生长的促进作用。因此它具有防止枯萎的作用和生发效果。组成：皮肤病学试剂的组成包含0.0001至5重量％的由式（1）表示的torilin。 Torilis japonica（Houtt。）DC。在有机溶剂如低级醇，乙酸乙酯，己烷或乙醚中加热3〜5次，在50〜100℃下加热1〜10小时，或者在0〜40℃下在上述溶剂中浸泡1〜30 天。提取物用真空干燥器彻底干燥。

7. 发明授权

KR100367992B1 올리고키토산의제조방법 有权
公开(公告)号：KR100367992B1
公开(公告)日：2003-05-16
申请号：KR1019980022394
申请日：1998-06-15
申请人： 주식회사 아모레퍼시픽그룹
发明人： 권순상 , 장이섭 , 이병곤 , 김완기 , 최종근 , 안수선 , 김진한
IPC分类号： C08B37/08
摘要： PURPOSE: The oligo chitosan having disaccharide-decasaccharide was manufactured with high purity and yield by using cellulase. CONSTITUTION: The chitosan obtained from chitin which was extracted from crab was dissolve in dilute aqueous hydrochloric acid and hydrolyzed by adding enzyme. The hydrolyzed reaction solution was heated to 80-100°C to inactivate the enzyme, and powdered to give oligo chitosan which had 5-10 degree of polymerization.
摘要翻译：目的：通过使用纤维素酶制造具有高纯度和产量的具有二糖 - 十糖的低聚壳聚糖。构成：将从蟹中提取的几丁质得到的壳聚糖溶解于稀盐酸水溶液中，加入酶进行水解。将水解的反应溶液加热到80-100℃以使酶失活，并粉化，得到聚合度为5-10度的寡聚脱乙酰壳多糖。

8. 发明授权

KR100368126B1 피지 분비 억제용 조성물 有权
标题翻译： 피지분비억제용조성피
公开(公告)号：KR100368126B1
公开(公告)日：2003-01-24
申请号：KR1020000058768
申请日：2000-10-06
申请人： 주식회사 아모레퍼시픽그룹
发明人： 손의동 , 박원석 , 남개원 , 이병곤
IPC分类号： A61K36/23 , A61K36/14 , A61P17/10
摘要： PURPOSE: A composition for inhibiting sebum secretion is provided, thereby treating diseases associated with sebum including the pimple, the enlargement of hair holes, depilation and dermatitis. CONSTITUTION: The composition for inhibiting sebum secretion contains at least one extract selected from the extracts of Torilis Fructus, Thujae semen and Mantidis Ootheca in an amount of 0.001 to 10 wt.% to the total weight of the composition, in which the extracts of Torilis Fructus, Thujae semen and Mantidis Ootheca are prepared by crushing the Torilis Fructus, Thujae semen and Mantidis Ootheca; adding organic solvent such as ethanol or methanol into the crushed mixture; and heating the mixture to 50 to 100 deg.C for 1 to 10 hours or dipping fresh Torilis Fructus, Thujae semen and Mantidis Ootheca in the organic solvent at 0 to 40 deg.C for 1 to 30 days.
摘要翻译：目的：提供一种用于抑制皮脂分泌的组合物，由此治疗与皮脂有关的疾病，包括疙瘩，毛孔扩大，脱毛和皮炎。组成：用于抑制皮脂分泌的组合物含有至少一种选自Torilis Fructus，Thujae semen和Mantidis Ootheca的提取物的提取物，其量为组合物总重量的0.001-10％重量，其中Torilis提取物 Fructus，Thujae semen和Mantidis Ootheca是通过粉碎Torilis Fructus，Thujae semen和Mantidis Ootheca来制备的; 将有机溶剂如乙醇或甲醇加入粉碎的混合物中; 并将混合物加热至50至100℃1至10小时，或在0至40℃下将新鲜Torilis Fructus，Thujae semen和Mantidis Ootheca浸入有机溶剂中1至30天。

9. 发明公开

KR1020030004889A 자외선에 의한 피부세포 손상을 억제하는 프럭토스1,6-디포스페이트 및 그의 염을 함유한 화장료 조성물 有权
标题翻译：含有蔗糖1,6-二磷酸盐及其盐的化妆品组合物通过紫外线辐射抑制皮肤损伤
公开(公告)号：KR1020030004889A
公开(公告)日：2003-01-15
申请号：KR1020010040631
申请日：2001-07-07
申请人： 주식회사 아모레퍼시픽그룹
发明人： 노민수 , 김수현 , 안수미 , 이병곤 , 이수환
IPC分类号： A61K8/55 , A61Q17/00
摘要： PURPOSE: A cosmetic composition containing D-fructose 1,6-diphosphate and a salt thereof is provided which causes no skin irritation and inhibits skin damage caused by irritation such as UV ray. Therefore it can be used as a cosmetic material playing a role of endogenous antioxidant substances for improving self-reducing power of skin cells. CONSTITUTION: The cosmetic composition contains 0.0001 to 20 parts by weight of D-fructose 1,6-diphosphate and a salt thereof, based on the total weight of the composition and reduces the concentration of an inflammatory intermediate factor of prostaglandins by inhibition of activity of cyclooxygenase-2.
摘要翻译：目的：提供含有D-果糖1,6-二磷酸酯及其盐的化妆品组合物，其不引起皮肤刺激并抑制由紫外线引起的刺激引起的皮肤损伤。因此，它可以用作扮演内源性抗氧化物质作用的化妆品，以提高皮肤细胞的自我减少能力。构成：化妆品组合物含有0.0001-20重量份的D-果糖1,6-二磷酸及其盐，基于组合物的总重量，通过抑制前列腺素的活性降低前列腺素的炎症中间因子的浓度环氧合酶-2。

10. 发明公开

KR1020020049341A 신규한 페닐환 유도체, 그의 제조방법 및 이를 포함하는약학 조성물 및 화장료 조성물 失效
标题翻译：新型苯环衍生物，其生产方法，以及含有它们的药物和化妆品组合物
公开(公告)号：KR1020020049341A
公开(公告)日：2002-06-26
申请号：KR1020000078491
申请日：2000-12-19
申请人： 김선여 , 최상윤 , 석경호 , 김상희 , 김호철 , 주식회사 아모레퍼시픽그룹
发明人： 김선여 , 김상희 , 최상윤 , 김호철 , 석경호 , 황재성 , 이병곤
IPC分类号： C07C15/52
摘要： PURPOSE: Provided are novel phenyl ring derivatives which has tyrosinase inhibiting and lightening effects, a production method thereof, and pharmaceutical and cosmetic composition containing the same. CONSTITUTION: The phenyl ring derivatives have a chemical structure represented by the formula I, in which R1, R2 and R3 are independently hydrogen, halogen or C1-4 alkoxy, X is a carbon atom or nitrogen atom, M is (i) 2-pyridyl, 3-pyridyl or 4-pyridyl, substituted with R4, (ii) 2-puryl or 3-puryl, substituted with R4, (iii) a phenyl ring represented by the formula I-1, in which R4 is a hydrogen, halogen, hydroxy or C1-4 alkoxy group, R5, R6, R7, R8 and R9 are a hydrogen or C1-4 alkoxy group, provided that R1 to R9 may be substituted.
摘要翻译：目的：提供具有酪氨酸酶抑制和减轻作用的新型苯环衍生物及其制备方法，以及包含其的药物和化妆品组合物。构成：苯环衍生物具有由式I表示的化学结构，其中R 1，R 2和R 3独立地为氢，卤素或C 1-4烷氧基，X为碳原子或氮原子，M为（ⅰ）2- 被R4取代的吡啶基，3-吡啶基或4-吡啶基，（ⅱ）被R4取代的2-吡啶基或3-芴基，（ⅲ）由式I-1表示的苯环，其中R4是氢，卤素，羟基或C 1-4烷氧基，R 5，R 6，R 7，R 8和R 9是氢或C 1-4烷氧基，条件是R 1至R 9可以被取代。

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