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1. 发明授权

KR101167628B1 흑삼을 함유하는 치매 예방 또는 치료 및 인지기능 개선 조성물 失效
标题翻译：包含黑金刚治疗或预防感染并改善认知功能的组合物
公开(公告)号：KR101167628B1
公开(公告)日：2012-07-23
申请号：KR1020110051428
申请日：2011-05-30
申请人： 주식회사 씨오투바이오 , 서원대학교산학협력단
发明人： 이재일 , 이상화 , 이미라 , 성창근
IPC分类号： A61K36/258 , A61K36/232 , A61K36/65 , A61P25/28
摘要： PURPOSE: A composition containing black ginseng for preventing and treating dementia is provided to highly suppress cetylcholinesterase and butyrylcholinesterase. CONSTITUTION: A pharmaceutical composition for preventing or treating dementia contains crude drug extract of black ginseng, Angelica gigas Nakai, Paeoniae lactiflora var. trichocarpa BUNGE., Astragalus membranaceus, Rehmannia glutinosa, Cnidii Rhizoma, and Glycyrrhizae Radix. The extract is prepared by dipping 4-6 year old black ginseng in 40-100% of grape juice at 0-20°C for 12-48 hours, steaming the grape juice-dipped white ginseng at 110-130°C for 10-60 minutes, drying, and repeating steaming and drying 2-5 times. A health functional food for treating dementia contains the crude drug extract.
摘要翻译：目的：提供一种含有人参用于预防和治疗痴呆症的组合物，以高度抑制十六烷基胆碱酯酶和丁酰胆碱酯酶。构成：用于预防或治疗痴呆症的药物组合物含有人参的生药提取物，当归，中华芍药，黄芪，黄芪，地黄，枸杞和甘草。该提取物通过在0-20℃下将4-6岁黑参浸入40-100％的葡萄汁中12-48小时，将葡萄汁浸渍的白参在110-130℃下蒸10分钟， 60分钟，干燥，重复蒸煮2-5次。用于治疗痴呆的保健功能食品含有生药提取物。

2. 发明公开

KR1020140022618A 흑인삼엽 추출물을 함유하는 아토피 질환 치료 또는 예방용 조성물 无效
标题翻译：一种包含黑皮诺金叶用于治疗和预防原发性疾病的组合物
公开(公告)号：KR1020140022618A
公开(公告)日：2014-02-25
申请号：KR1020120088933
申请日：2012-08-14
申请人： 서원대학교산학협력단 , 주식회사 씨오투바이오
发明人： 송진욱 , 이상화 , 이재일 , 송규용
IPC分类号： A61K36/258 , A61P17/00
CPC分类号： A61K36/258 , A23L33/105 , A23V2002/00 , A23V2200/318 , A23V2250/2124
摘要： The present invention relates to a composition comprising a black Panax ginseng leaf extract for preventing, treating, or alleviating an atopic disease. The black Panax ginseng leaf extract of the present invention has an outstanding effect of reducing secretion of atopy inducers such as MCP-1, IL-6, and IL-8 in THP-1 cells. Thus, the black Panax ginseng leaf extract can be used as a drug effective for preventing or treating the atopic disease, a dietary supplement effective for relieving atopic skin, food additives, or cosmetics.
摘要翻译：本发明涉及包含用于预防，治疗或缓解特应性疾病的黑色人参叶提取物的组合物。本发明的黑色人参叶提取物具有减少THP-1细胞中特应性诱导剂如MCP-1，IL-6和IL-8分泌的突出效果。因此，黑色人参叶提取物可用作有效预防或治疗特应性疾病的药物，有助于缓解特应性皮肤，食品添加剂或化妆品的膳食补充剂。

3. 发明授权

KR101374351B1 흑인삼꽃봉오리 추출물을 유효성분으로 함유하는 아토피질환 치료 및 예방용 조성물 有权
标题翻译：一种组合物，其包含用于治疗和预防特应性疾病的黑人参的干燥花芽粉末
公开(公告)号：KR101374351B1
公开(公告)日：2014-03-19
申请号：KR1020120009423
申请日：2012-01-31
申请人： 대전대학교 산학협력단 , 주식회사 씨오투바이오
发明人： 송규용 , 이재일 , 김동희 , 최학주
IPC分类号： A61K36/258 , A61P17/00
摘要： 본 발명은 흑인삼꽃봉오리 추출물을 유효성분으로 함유하는 아토피 질환의 예방 및 치료를 위한 조성물에 관한 것으로, 본 발명의 흑인삼꽃봉오리 추출물은 THP-1 세포에서의 MCP-1, IL-6, IL-8 등의 아토피 유발 인자의 분비를 감소시키는 효능을 나타내므로 아토피질환 치료에 유용한 의약품 및 건강기능식품, 또는 식품첨가물로 이용될 수 있다.

4. 发明公开

KR1020130088283A 흑인삼꽃봉오리 추출물을 유효성분으로 함유하는 아토피질환 치료 및 예방용 조성물 有权
标题翻译：一种包含黑芍药干粉花粉治疗和预防原发性疾病的组合物
公开(公告)号：KR1020130088283A
公开(公告)日：2013-08-08
申请号：KR1020120009423
申请日：2012-01-31
申请人： 대전대학교 산학협력단 , 주식회사 씨오투바이오
发明人： 송규용 , 이재일 , 김동희 , 최학주
IPC分类号： A61K36/258 , A61P17/00
CPC分类号： A61K36/258 , A23L33/105 , A23V2002/00 , A23V2200/318 , A23V2250/2124
摘要： PURPOSE: A composition containing a flower bud extract of black Panax ginseng is provided to reduce the secretion of atopic dermatitis-inducing factors in cells treated with a mite extract, thereby preventing and treating atopic dermatitis. CONSTITUTION: A pharmaceutical composition for preventing and treating atopic dermatitis contains a flower bud extract of black Panax ginseng as an active ingredient. A method for preparing the flower bud extract of black Panax ginseng comprises the steps of: washing and drying flower buds of 4-7 year old Panax ginseng at 25-65°C for 12-36 hours; steaming the dried flower buds under the pressure of 0.05-0.45 MPa at 95-155°C for 3-9 hours; and drying the steamed flower buds at 40-80°C for 8-16 hours to have a moisture content of 14% or less. The extract is a crude extract (BGFE) or a butanol-soluble extract of black Panax ginseng flower buds. A health food for preventing and treating atopic dermatitis contains the extract as an active ingredient.
摘要翻译：目的：提供一种含黑色人参的花蕾提取物的组合物，以减少用螨提取物处理的细胞中特应性皮炎诱导因子的分泌，从而预防和治疗特应性皮炎。构成：用于预防和治疗特应性皮炎的药物组合物含有黑色人参的花芽提取物作为活性成分。一种黑人参人参花蕾提取物的制备方法，包括以下步骤：将4-7岁老年人参的花蕾在25-65℃下洗涤干燥12-36小时; 在0.05-0.45MPa的压力下在95-155℃下烘干干燥的花芽3-9小时; 并将蒸花在40-80℃下干燥8-16小时，使其含水量为14％以下。提取物是黑色人参花蕾的粗提物（BGFE）或丁醇可溶性提取物。用于预防和治疗特应性皮炎的保健食品含有提取物作为活性成分。

5. 发明公开

KR1020090027515A 해충 기피 활성을 갖는 한방 추출물 및 그 제조방법 无效
标题翻译：用于肠内营养液的方剂医药提取物及其制造方法
公开(公告)号：KR1020090027515A
公开(公告)日：2009-03-17
申请号：KR1020070092787
申请日：2007-09-12
申请人： 주식회사 씨오투바이오
发明人： 박성민 , 박지영 , 이재일
IPC分类号： A01N65/16 , A01N65/08
CPC分类号： A01N65/16 , A01N65/08 , A23B7/14 , C09K17/32
摘要： A manufacturing method of extract having killing insects is provided to use environment-friendly natural material and to solve problem due to remain agricultural medicines. A manufacturing method of extract having killing insects comprises steps of: injecting extraction solvent to Rhododendron brachycarpum and Paulownia coreana into a weight ratio of 1: 10~200; extracting extracts in which solvent is put and filtering it; reducing pressure and concentrating the extracted extracts; and mixing the concentrated and decompressed extracts to constant rate.
摘要翻译：提供具有杀昆虫的提取物的制造方法，使用环境友好的天然材料，并解决由于保留农药而引起的问题。具有杀昆虫的提取物的制造方法包括以下步骤：将提取溶剂注入杜鹃花brachycarpum和Paulownia coreana重量比为1：10〜200; 提取其中溶剂的提取物并过滤; 降低压力并浓缩提取的提取物; 并将浓缩和减压提取物混合至恒定速率。

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