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    • 2. 发明公开
    • 흑인삼꽃봉오리 추출물을 유효성분으로 함유하는 아토피질환 치료 및 예방용 조성물
    • 一种包含黑芍药干粉花粉治疗和预防原发性疾病的组合物
    • KR1020130088283A
    • 2013-08-08
    • KR1020120009423
    • 2012-01-31
    • 대전대학교 산학협력단주식회사 씨오투바이오
    • 송규용이재일김동희최학주
    • A61K36/258A61P17/00
    • A61K36/258A23L33/105A23V2002/00A23V2200/318A23V2250/2124
    • PURPOSE: A composition containing a flower bud extract of black Panax ginseng is provided to reduce the secretion of atopic dermatitis-inducing factors in cells treated with a mite extract, thereby preventing and treating atopic dermatitis. CONSTITUTION: A pharmaceutical composition for preventing and treating atopic dermatitis contains a flower bud extract of black Panax ginseng as an active ingredient. A method for preparing the flower bud extract of black Panax ginseng comprises the steps of: washing and drying flower buds of 4-7 year old Panax ginseng at 25-65°C for 12-36 hours; steaming the dried flower buds under the pressure of 0.05-0.45 MPa at 95-155°C for 3-9 hours; and drying the steamed flower buds at 40-80°C for 8-16 hours to have a moisture content of 14% or less. The extract is a crude extract (BGFE) or a butanol-soluble extract of black Panax ginseng flower buds. A health food for preventing and treating atopic dermatitis contains the extract as an active ingredient.
    • 目的:提供一种含黑色人参的花蕾提取物的组合物,以减少用螨提取物处理的细胞中特应性皮炎诱导因子的分泌,从而预防和治疗特应性皮炎。 构成:用于预防和治疗特应性皮炎的药物组合物含有黑色人参的花芽提取物作为活性成分。 一种黑人参人参花蕾提取物的制备方法,包括以下步骤:将4-7岁老年人参的花蕾在25-65℃下洗涤干燥12-36小时; 在0.05-0.45MPa的压力下在95-155℃下烘干干燥的花芽3-9小时; 并将蒸花在40-80℃下干燥8-16小时,使其含水量为14%以下。 提取物是黑色人参花蕾的粗提物(BGFE)或丁醇可溶性提取物。 用于预防和治疗特应性皮炎的保健食品含有提取物作为活性成分。
    • 5. 发明公开
    • ISRK 복합생약 추출물을 포함하는 당뇨병 및 당뇨합병증 예방 및 치료를 위한 조성물
    • 包含ISRK组合提取物的组合物,用于预防和治疗糖尿病和糖尿病并发症
    • KR1020130090941A
    • 2013-08-16
    • KR1020120012076
    • 2012-02-07
    • 대전대학교 산학협력단이해균
    • 이해균송규용김동희최학주
    • A61K36/81A61K36/899A61K36/30A61P3/10
    • A61K36/00A23V2200/328A61K36/28A61K36/286A61K36/30A61K36/605A61K36/899A61K36/8998A61K2236/33Y10S514/866
    • PURPOSE: A composition containing an extract of ISRK crude drug complex for preventing and treating diabetes and diabetes complication is provided to obtain a pharmaceutical composition and a health food for preventing and treating diabetes and diabetes complication without insulin resistance. CONSTITUTION: A pharmaceutical composition for preventing and treating diabetes and diabetes complication contains 0.001-50 wt% of an extract of crude drug complex as an active ingredient. The crude drug complex includes Helianthus tuberosus, Circium japonicum, malt, Lithospermum erythrorhizon, bamboo leaves, Cortex mori radicis, Grifola umbellate, Poria cocos, corn silk, Citrus unshiu peels, Hovenia dulcis THUNB, Hovenia dulcis, Lycium chinense, Ulmus macrocarpa, jujube, Longanae Arillus, Astragalus membranaceus BUNGE, Atractylodes japonica, Cornus fruit, Glycyrrhizae radix, Angelica gigas, Paeoniae Radix, Rehmanniae radix Cnidii rhizoma, Eucommia ulmoides, and Acanthopanacis cortex. The extract is prepared using a polar solvent selected among water, C1-C4 alcohols, and a mixture thereof. [Reference numerals] (AA) 18th August; (BB) 25th August; (CC) 1st September; (DD) 8th September; (EE) 15th September; (FF) 22th September; (GG) 29th September
    • 目的:提供含有用于预防和治疗糖尿病和糖尿病并发症的ISRK生药复合物提取物的组合物,以获得用于预防和治疗糖尿病并且没有胰岛素抵抗的糖尿病并发症的保健食品。 构成:用于预防和治疗糖尿病和糖尿病并发症的药物组合物含有作为活性成分的生药物复合物提取物的0.001-50重量%。 生药复合物包括向日葵,日葵,麦芽,紫草,竹叶,茯苓,茯苓,玉米丝,柑橘,枸杞,枸杞,枸杞,枸杞,枣, ,龙眼,illus,黄芪,黄芪,枸杞,甘草,当归,芍药,地黄,杜仲和刺五加皮质。 提取物使用选自水,C1-C4醇及其混合物的极性溶剂制备。 (附图)(AA)8月18日; (BB)8月25日; (CC)9月1日; (DD)9月8日; (EE)9月15日; (FF)9月22日; (GG)9月29日
    • 6. 发明公开
    • 흑삼 추출물을 유효성분으로 함유하는 아토피질환 치료 및 예방용 조성물
    • 包含红姜提取物治疗和预防原发性疾病的组合物
    • KR1020130080644A
    • 2013-07-15
    • KR1020120001554
    • 2012-01-05
    • 대전대학교 산학협력단
    • 송규용김동희최학주
    • A61K36/258A61P17/00
    • PURPOSE: A composition containing a black ginseng extract is provided to be effectively used as a composition for preventing and treating an atopic disease since the composition does not have a side effect on a body nor a toxicity and have an atopy inducer excretion reducing effect. CONSTITUTION: A pharmaceutical composition for preventing and treating an atopic disease contains a black ginseng extract as an active ingredient. The black ginseng is obtained through one cycle of the following steps of: a first step of washing Korean ginseng roots of 4 to 6 years old in an ultrasonic cleanser for 10 minutes for 3 times and drying the ginseng roots at a temperature of 35 to 45°C for 22 to 26 hours; a second step of steaming the dried Korean ginseng roots in a steamer at a temperature of 85 to 105°C for 4 to 6 hours, except a pre-heating time; a third step of drying the Korean ginseng roots at a temperature of 55 to 65°C for 10 to 14 hours; a fourth step of steaming the Korean ginseng roots at pressure of 0.1 to 0.20 MPa at a temperature of 110 to 120°C for 5 to 7 hours; and a fifth step of drying the Korean ginseng roots in a dryer for 10 to 14 hours to obtain black ginseng roots.
    • 目的:提供含有黑参提取物的组合物作为预防和治疗特应性疾病的组合物,因为该组合物对身体不具有副作用或毒性,并具有特应性诱导剂排泄减少作用。 构成:用于预防和治疗特应性疾病的药物组合物含有黑参提取物作为活性成分。 通过以下步骤的一个循环获得黑参:第一步是在超声清洗剂中洗涤4至6岁的韩参人参10分钟3次,并在35至45℃的温度下干燥人参根 ℃22〜26小时; 除了预热时间之外,将干燥的韩国人参根蒸在蒸发器中,在85至105℃的温度下蒸煮4至6小时; 第三步,在55〜65℃的温度下干燥韩国人参根10〜14小时; 在110〜120℃的温度下,在0.1〜0.20MPa的压力下蒸煮韩参人参根5〜7小时的第4步骤; 第五步,在干燥机中干燥10〜14小时的韩国人参根,获得黑参根。