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    • 2. 发明公开
    • 두피 보호용 산화형 염모제 조성물
    • 用于保护标准品的氧化染发组合物
    • KR1020140117096A
    • 2014-10-07
    • KR1020130032052
    • 2013-03-26
    • 주식회사 서울화장품주식회사 세바바이오텍서원대학교산학협력단강원대학교산학협력단
    • 이현용임혜원김학수이정구장민김지선최운용최우석최철순
    • A61K8/34A61K8/19A61K8/97A61Q5/00
    • A61K8/36A61K8/342A61K8/37A61K8/97A61K2800/72A61K2800/82A61Q5/10A61Q17/04
    • The present invention relates to an oxidized hair dye composition comprising an oxidized hair dye, a sunscreen, and at least one selected among natural substances, a calendula extract, a Ulmus macrocarpa extract, a Scutellaria baicalensis extract. More specifically, since the hair dye composition of the present invention contains a sunscreen in addition to the existing oxidized hair dye, the composition effectively prevents an oxidized dye polymer formed on the cortex of the hair from degrading by ultraviolet rays, hence delaying the decolorization of the dyed hair; thereby expecting the effects of maintaining the color of the dyed hair for a long time. Additionally, the hair dye composition is mixed with the natural substances including calendula, Ulmus macrocarpa, and Scutellaria baicalensis, thereby preventing allergic contact dermatitis caused by irritative substances contained in the hair dye. Therefore, the oxidized hair dye manufactured by a method of the present invention can be used by a person having hypersensitive skin without side effects.
    • 本发明涉及包含氧化染发剂,防晒剂和选自天然物质,金盏花提取物,榆树提取物,黄芩提取物中的至少一种的氧化染发组合物。 更具体地说,由于除了现有的氧化染发剂以外,本发明的染发剂组合物还含有防晒剂,因此有效地防止了形成在毛发皮质上的氧化染料聚合物因紫外线而降解,因此延迟了脱色 染发 从而期望长时间保持染发的颜色的效果。 另外,将染发剂组合物与包括金盏花,榆木,黄芩的天然物质混合,从而防止由染发剂中含有的刺激物质引起的过敏性接触性皮炎。 因此,通过本发明的方法制造的氧化染发剂可以由具有过敏皮肤的人使用而没有副作用。
    • 3. 发明公开
    • 감압 재순환 고속 증숙 공정장치를 이용한 인삼의 저분자 진세노사이드 함량 증진 방법
    • 通过分解回收高速蒸馏过程装置提高金山低分子金属皂苷含量的制备
    • KR1020140098503A
    • 2014-08-08
    • KR1020130011257
    • 2013-01-31
    • 주식회사 세바바이오텍서원대학교산학협력단강원대학교산학협력단
    • 이현용최운용서용창김지선이춘근최우석임혜원
    • A23L19/00A47J27/00
    • The present invention relates to a decompression-recirculation high-speed steaming device and a method for producing ginseng having an increased low-molecular ginsenosides content and, more specifically, to a method for producing the ginseng in which the content of the low-molecular ginsenosides such as Rh2, Rg2, Rg3, and CK is increased by inputting ginseng into the device of the present invention and steaming the inputted ginseng under a decompression condition. When steaming ginseng by using the decompression-recirculation high-speed steaming device of the present invention, an effect of rapidly producing red ginseng by effectively increasing the low-molecular ginsenosides (Rh2, Rg2, Rg3, and CK) contained in ginseng can be obtained and an effect of having a little content of benzopyrene that is a carcinogen by not going through a repetitive steaming step for a long time as in the past. Furthermore, when steaming ginseng by using the device of the present invention, a value of the ginseng can be increased by applying the method to cheap ginseng as a huge morphologic change of ginseng is not generated. Therefore, the decompression-recirculation high-speed steaming device and method for producing ginseng having the increased low-molecular ginsenosides content of the present invention can be usefully applied in not only medicine and medical supplies but also functional food and cosmetics.
    • 本发明涉及一种减压 - 再循环高速蒸汽装置和一种生产具有增加的低分子人参皂甙含量的人参的方法,更具体地说,涉及一种生产人参的方法,其中低分子量人参皂苷的含量 通过将人参输入本发明的装置并在减压条件下蒸煮输入的人参,从而增加了Rh2,Rg2,Rg3和CK。 当通过使用本发明的减压 - 再循环高速蒸汽装置蒸人参时,可以获得通过有效增加人参中所含的低分子量人参皂甙(Rh2,Rg2,Rg3和CK)迅速生产红参的效果 并且通过与过去不经历长时间的重复蒸汽步骤,具有作为致癌物的苯并芘含量少的效果。 此外,当通过使用本发明的装置蒸制人参时,通过将该方法应用于廉价人参可以提高人参的价值,因为不会产生人参的巨大形态变化。 因此,本发明的具有增加的低分子量人参皂甙含量的人参的减压 - 再循环高速蒸汽装置和制造方法不仅可用于医药和医疗用品,还可用于功能性食品和化妆品。
    • 4. 发明公开
    • 커피 발효물 및 이의 추출물을 유효성분으로 포함하는 기능성 커피 음료 조성물 및 이의 제조방법
    • 功能性咖啡饮料组合物,包括咖啡发酵产品及其提取物及其生产方法
    • KR1020140027614A
    • 2014-03-07
    • KR1020120085913
    • 2012-08-06
    • 강원대학교산학협력단서원대학교산학협력단주식회사 세바바이오텍
    • 이현용최운용서용창송치호이춘근임혜원
    • A23F5/28A23F5/40
    • The present invention relates to a manufacturing method of a functional coffee drink composition including fermented coffee products (coffee beans or by-products) and an extract thereof, and, more specifically, to a manufacturing method of a functional coffee drink composition including fermented liquid and fermented coffee residual extract, and a functional coffee drink composition manufactured thereby, wherein the fermented liquid is obtained by fermenting unprocessed coffee beans or coffee by-products, which are mostly discarded without being consumed, by using lactobacillus, and the fermented coffee residual extract is obtained by extracting the dried fermented coffee residue besides the fermented liquid, with ethanol. As the manufacturing method of the present invention is able to enhance elution of chlorogenic acid in the coffee through a simple process, the composition of the present invention manufactured through the method contains a large quantity of chlorogenic acid having a lipoperoxide production suppressing effect, cholesterol biosynthesis inhibition effect, an anti-oxidation activity, an anti-inflammatory effect and an anti-cancer effect, enabling the composition to be used as a functional coffee drink composition. Further, the manufacturing method of the present invention utilizes coffee beans, of which the unit price is cheap, or discarded coffee by-products to create novel health materials having functionalities, to provide an eco-friendly effect through the recycling of waste. [Reference numerals] (AA) Free radical elimination rate (%); (BB) Concentration (쨉m); (CC) Hydrothermal extract of coffee beans (Comparative example); (DD) Hydrothermal extract of coffee by-product (Comparative example)
    • 本发明涉及一种包含发酵咖啡产品(咖啡豆或副产物)及其提取物的功能性咖啡饮料组合物的制造方法,更具体地,涉及包含发酵液体的功能性咖啡饮料组合物的制造方法, 发酵咖啡残余提取物和由此制造的功能性咖啡饮料组合物,其中,所述发酵液体通过使用乳杆菌发酵未处理大部分被废弃而未被消耗的未加工咖啡豆或咖啡副产物而获得,所述发酵咖啡残余提取物为 通过用乙醇萃取除了发酵液之外的干燥的发酵咖啡残渣获得。 由于本发明的制造方法能够通过简单的方法提高咖啡中的绿原酸的洗脱,所以通过该方法制造的本发明的组合物含有大量具有脂肪过氧化物产生抑制作用的绿原酸,胆固醇生物合成 抑制效果,抗氧化活性,抗炎作用和抗癌作用,使得该组合物可用作功能性咖啡饮料组合物。 此外,本发明的制造方法利用单价廉价的咖啡豆或者丢弃的咖啡副产品来制造具有功能的新型健康材料,通过废物的再循环来提供环保效果。 (标号)(AA)自由基消除率(%); (BB)浓度(쨉m); (CC)咖啡豆水热提取物(比较例); (DD)咖啡副产物水热提取物(比较例)
    • 7. 发明授权
    • 복합 균주를 이용한 산삼배양근 발효물의 제조방법 및 상기 발효물을 함유한 기능성 화장료 조성물
    • 使用复合菌株的发酵野参人参根的方法和包含它们的化妆品组合物
    • KR101440469B1
    • 2014-09-17
    • KR1020120082318
    • 2012-07-27
    • 강원대학교산학협력단서원대학교산학협력단주식회사 세바바이오텍
    • 이현용최운용서용창송치호이춘근임혜원
    • A61K8/97A61K8/99A61Q19/02A61Q19/08
    • 본 발명은 복합 균주를 이용한 산삼배양근 발효물의 제조방법 및 상기 발효물을 함유한 기능성 화장료 조성물에 관한 것으로서, 보다 구체적으로 본 발명은 락토바실러스 에시도필러스(
      Lactobacillus acidophilus ), 비피도박테리아 롱검(
      Bifidobacterium Longum ) 및 락토바실러스 람노서스 HK-9(
      Lactobacillus rhamnosus HK-9)으로 이루어진 군 중에서 선택되는 하나 이상의 균주를 이용하여 발효시킨 산삼배양근의 발효 추출물을 유효성분으로 포함하고 상기 발효 추출물은 화장료 조성물 총 중량에 대하여 0.001~20 중량%로 포함된 화장료 조성물; 및 (a) 산삼배양근과 MRS 배양 배지를 1:10 중량비로 혼합하는 단계; (b) 락토바실러스 람노서스 HK-9(
      Lactobacillus rhamnosus HK-9)를 상기 배양 배지의 5 중량%의 농도로 접종하고 24시간 동안 배양하는 단계; (c) 락토바실러스 에시도필러스(
      Lactobacillus acidophilus )를 추가로 접종하고, 멸균된 MRS 배지를 250ml 첨가한 다음, 12시간 동안 배양 하는 단계; 및 (d) 멸균된 MRS 배지 250ml을 추가로 첨가한 후, 비피도박테리아 롱검(
      Bifidobacterium Longum ) 균주를 접종하고 24시간 동안 배양하면서 발효시키는 단계를 포함하는 산삼배양근의 발효물을 제조하는 방법에 관한 것으로서, 본 발명의 방법으로 제조된 산삼배양근의 발효물은 베타-글루코시다제 효소의 활성을 증진시켜 발효물 내에 Rg3, Rh2 및 Compound K 함량을 증진시킬 수 있어 피부미백 및 주름개선을 위한 화장품의 제조에 사용할 수 있는 효과가 있다.
    • 10. 发明公开
    • 진세노사이드 Rh2 및 진세노사이드 Rg3를 함유하는 기능성 화장료 조성물
    • 功能性化妆品组合物,包含GINSENOSIDES RH2和RG3
    • KR1020140013791A
    • 2014-02-05
    • KR1020120082283
    • 2012-07-27
    • 강원대학교산학협력단서원대학교산학협력단주식회사 세바바이오텍(주) 피엘코스메틱
    • 이현용최운용서용창송치호이춘근임혜원황보정아
    • A61K8/63A61Q19/00
    • A61K8/602A61K8/02A61K8/63A61Q19/00A61Q19/02A61Q19/08
    • The present invention relates to a functional cosmetic composition comprising low molecular ginsenosides Rh2 and Rg3 isolated from ginseng, red ginseng, and cultured wild ginseng roots and more specifically, to a functional cosmetic composition which includes the ginsenosides Rh2 and Rg3 with a mixing ratio of 2:8 to 4:6, and shows excellent effects such as relieving atopic dermatitis, acne, skin whitening, and anti-wrinkle when 1-5 wt% of the functional cosmetic composition is included based on the total weight of the ginsenosides Rh2 and Rg3 mixture as solid powder. The cosmetic composition according to the present invention shows better anti-wrinkle, skin whitening, relieving acne, and atopic dermatitis than when applying only the ginsenosides Rh2 and Rg3. In addition, the cosmetic composition of the present invention is a natural material and edible so that the composition including the same as an active ingredient is safe for long term use and has no toxicity and side effects. [Reference numerals] (AA) Cell proliferation effects (%); (BB) Concentration of ginsenoside Rh2 and Rg3
    • 本发明涉及一种功能性化妆品组合物,其包含从人参,红参和培养的人参根分离的低分子量人参皂甙Rh2和Rg3,更具体地,涉及包含人参皂甙Rh2和Rg3的功能性化妆品组合物,其混合比为2 :8〜4:6,基于人参皂苷Rh2和Rg3的总重量,当包含功能性化妆品组合物的1-5重量%时,显示出优异的效果,例如缓解特应性皮炎,痤疮,皮肤美白和抗皱纹 混合物为固体粉末。 与仅使用人参皂甙Rh2和Rg3相比,本发明的化妆品组合物显示出更好的抗皱,皮肤美白,缓解痤疮和特应性皮炎。 此外,本发明的化妆品组合物是天然材料,可食用,使得其作为活性成分的组合物对于长期使用是安全的,并且没有毒性和副作用。 (AA)细胞增殖效应(%) (BB)人参皂苷Rh2和Rg3的浓度