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1. 发明专利

JP4185859B2 Automated analyzer 有权
公开(公告)号：JP4185859B2
公开(公告)日：2008-11-26
申请号：JP2003421781
申请日：2003-12-19
申请人：株式会社日立ハイテクサイエンスシステムズ , 株式会社日立ハイテクノロジーズ
发明人：哲也磯部 , 正治西田 , 克明高橋
IPC分类号： G01N35/02 , B01L7/02 , G01N21/03 , G01N21/15 , G01N21/25 , G01N21/47 , G01N35/00
CPC分类号： G01N21/4738 , B01L7/02 , B01L2200/0684 , G01N21/0332 , G01N35/025 , G01N2035/00396

2. 发明专利

JP4077649B2 Solution concentration apparatus 有权
公开(公告)号：JP4077649B2
公开(公告)日：2008-04-16
申请号：JP2002110386
申请日：2002-04-12
申请人：ユースエンジニアリング株式会社
发明人：亨安田 , 敏彦戸田 , 俊朗近藤
IPC分类号： G01N1/10 , G01N1/28 , B01L7/02 , B01L9/06 , G01N1/36 , G01N33/00
摘要： PROBLEM TO BE SOLVED: To effectively heat a solution thereby reducing a concentration time and improving ease of working in a gas blow type concentrator which concentrates the solution by blowing gas to vaporize solvent. SOLUTION: Heating fixtures which are made of a material with good thermal conductivity and have an inner structure fitting sample tubes 1a, 1b, cover around at least the side of the sample tubes over a wide area, when the sample tubes 1a, 1b are set in a holder 2 having a heating means, and thereby effectively heating the solution and increasing the vaporization speed. COPYRIGHT: (C)2004,JPO

3. 发明专利

JP2005127608A Constant-temperature liquid tank 有权
标题翻译：恒温液体罐
公开(公告)号：JP2005127608A
公开(公告)日：2005-05-19
申请号：JP2003363223
申请日：2003-10-23
申请人： Smc Corp , Smc株式会社
发明人： MINOURA ATSUSHI
IPC分类号： F25D11/00 , B01L7/00 , B01L7/02 , F25B21/02 , F25B21/04 , F25D13/00
CPC分类号： B01L7/02 , B01L2300/1822 , B01L2300/185 , B01L2400/0475 , F25B2321/0251
摘要： PROBLEM TO BE SOLVED: To provide a constant-temperature liquid tank capable of easily performing the heat exchange between a heat source and the liquid, efficiently keeping a constant-temperature of the liquid, and easily and quickly adjusting the temperature even when a dipped article of which the temperature is to be controlled, exists in the tank, with respect to the constant-temperature liquid tank using a thermo module.
SOLUTION: This constant-temperature liquid tank 1A wherein the temperature of the liquid in the tank is adjusted by a heat supply device 9 comprising the thermo module 31 adjusting the temperature by Pertier effect, comprises an outer tank 3 for storing the liquid, an inner tank 5 mounted inside of the outer tank through a clearance 17, having a through hole 21 on its side wall 19 for allowing the liquid to flow therein from the outer tank and having a hole 25 on a center of a bottom part 23, and a stirring machine 7 for guiding the liquid flowing from the hole of the bottom part of the inner tank through between side walls of the inner and outer tanks, to an upper part by a rotary blade 11 mounted on the center of the bottom part between the outer tank and the inner tank. The thermo module 31 is mounted on an outer face of the side wall 15 of the outer tank to control the liquid flowing between the inner and outer tanks to a set temperature.
COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：为了提供能够容易地进行热源与液体之间的热交换的恒温液体罐，有效地保持液体的恒定温度，并且即使当相对于使用热模块的恒温液体罐，存储有要控制温度的浸渍制品。解决方案：这种恒温液罐1A，其中通过包括通过Pertier效应调节温度的热模块31的供热装置9调节罐中的液体的温度，包括用于储存液体的外罐3 ，通过间隙17安装在外罐内部的内罐5，其在其侧壁19上具有通孔21，用于允许液体从外罐流入其中并且在底部23的中心具有孔25 以及搅拌机7，其用于将从内罐的底部的孔流过的液体通过内罐和外罐的侧壁引导到上部，该旋转刀11安装在底部的中心在外箱和内箱之间。热模块31安装在外罐的侧壁15的外表面上，以将在内罐和外罐之间流动的液体控制到设定温度。版权所有（C）2005，JPO＆NCIPI

4. 发明专利

JP2003024063A Method for continuously amplifying dna and device for the same 审中-公开
标题翻译：连续放大DNA及其装置的方法
公开(公告)号：JP2003024063A
公开(公告)日：2003-01-28
申请号：JP2001212610
申请日：2001-07-12
申请人： Toshio Kawai , 敏夫川井
发明人： KAWAI TOSHIO
IPC分类号： C12N15/09 , B01L7/00 , B01L7/02 , C12M1/00
CPC分类号： B01L7/525 , B01L7/02 , B01L2300/185 , B01L2400/0487
摘要： PROBLEM TO BE SOLVED: To provide a method for continuously amplifying a DNA, capable of performing the amplification reaction in a large amount and effectively and continuously by performing the temperature-treatments of a reaction liquid containing a DNA fragment as a mold and reagent liquid by using thermal exchange liquid at different temperatures.
SOLUTION: The device for continuously amplifying the DNA has a reaction liquid vessel 1, a thermostat vessel 2 for degeneration, a thermostat vessel 3 for annealing, a thermostat vessel 4 for elongation, a circulating passage 6 circulating through each of the vessels 1, 2, 3, 4, and a pump 7 operating to supply and transfer the reaction liquid 5 in the circulating passage 6 in one direction. By transferring the reaction liquid 5 with the pump 7, the reaction liquid 5 is maintained at prescribed temperatures in each of the thermostat vessels 2, 3, 4. As compared with a batch method, since the amplification reaction can be performed under preferable conditions by improving heat exchange efficiency to make the reaction liquid 5 at prescribed temperature states uniformly and also rapidly, amplification efficiency can be widely improved. Since the amplification reaction is performed by transferring and supplying the reaction liquid 5 by circulation, it is possible to set the amplification amount of the DNA per on time as a large amount.
COPYRIGHT: (C)2003,JPO
摘要翻译：要解决的问题：提供一种连续扩增DNA的方法，其能够通过对含有作为模具的DNA片段和试剂液体的反应液进行温度处理，能够大量且有效且连续地进行扩增反应，在不同温度下使用热交换液体。解决方案：用于连续放大DNA的装置具有反应液容器1，用于退化的恒温器2，用于退火的恒温器3，用于伸长的恒温器4，循环通过每个容器1,2的循环通道6 ，3,4，以及在循环通道6中向一个方向供给和转移反应液5的泵7。通过将反应液5与泵7一起转移，在各恒温容器2,3,4中将反应液5维持在规定的温度。与间歇法相比，扩增反应可以在优选的条件下进行，提高热交换效率使得反应液5在规定的温度状态下均匀且快速地，扩大效率可以得到广泛的提高。由于通过循环转移和供给反应液5进行扩增反应，因此可以大量地设定DNA的扩增量。

5. 实用新型

JP3038839U 失效
公开(公告)号：JP3038839U
公开(公告)日：1997-06-30
申请号：JP1289096
申请日：1996-12-18
IPC分类号： B01L7/02

6. 发明专利

JPH0793875B2 失效
公开(公告)号：JPH0793875B2
公开(公告)日：1995-10-11
申请号：JP10790589
申请日：1989-04-28
IPC分类号： C12M3/00 , B01L7/02 , C12M1/00 , C12N5/02

7. 发明专利

JPH05503466A 失效
公开(公告)号：JPH05503466A
公开(公告)日：1993-06-10
申请号：JP50587191
申请日：1991-02-28
IPC分类号： B01L7/02 , B01L7/00 , B01L7/04 , C12M1/36 , G01N35/00 , G05D23/00 , G05D23/19 , H05B6/68 , H05B6/80

8. 发明专利

JPH04330272A INCUBATION APPARATUS 失效
公开(公告)号：JPH04330272A
公开(公告)日：1992-11-18
申请号：JP12526691
申请日：1991-04-26
申请人： SHIMADZU CORP
发明人： KITA JUNICHI , FUKUSHIMA SHIGERU , NISHIMURA NAOYUKI
IPC分类号： C12M1/38 , B01L7/02 , C12M1/00
摘要： PURPOSE:To obtain the subject apparatus effective for shortening the treating time of a sample and reducing electric power consumption and useful for gene amplification reaction, etc., by heating and cooling a reaction vessel in definite sequence using plural heating and cooling media controlled to different temperatures. CONSTITUTION:Plural media 2a, 2b, 2c for the heating or cooling of a reaction vessel are controlled to different temperatures. The media are made to independently contact with a reaction vessel 4 in definite sequence to enable the control of the reaction vessel 4 at different temperatures according to the heating and cooling sequence with the media 2a, 2b, 2c. Concretely, in the case of gene amplification reaction, the blocks 2a, 2b, 2c containing the media are controlled to 94 deg.C, 54 deg.C and 72 deg.C, respectively, and the reaction vessel 4 containing a sample is successively brought into contact with the blocks 2a, 2b, 2c to effect the thermal denaturation of the sample at 94 deg.C, the annealing of the primer at 54 deg.C and the synthesis of a DNA chain at 72 deg.C.

9. 发明专利

JPH0375209B2 失效
公开(公告)号：JPH0375209B2
公开(公告)日：1991-11-29
申请号：JP20102088
申请日：1988-08-10
IPC分类号： B01F7/16 , B01F9/10 , B01F9/22 , B01F11/00 , B01L7/02

10. 发明专利

JPH03504774A 失效
公开(公告)号：JPH03504774A
公开(公告)日：1991-10-17
申请号：JP50416289
申请日：1989-03-24
IPC分类号： B01L7/02 , B01L3/00 , B01L7/00 , G05D23/00 , G05D23/19 , G05D23/24

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