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    • 8. 发明专利
    • Preparation for external use and method for producing the same
    • 用于外部使用的制备及其生产方法
    • JP2007314483A
    • 2007-12-06
    • JP2006148002
    • 2006-05-29
    • Amino Up Chemical Co LtdIchimaru Pharcos Co Ltd一丸ファルコス株式会社株式会社アミノアップ化学
    • TSUBOI TAKAYUKIKAWASAKI YUJIWAKAMEI KOJI
    • A61K8/49A61K8/34A61K8/97A61Q19/00
    • PROBLEM TO BE SOLVED: To provide a preparation for external use obtained by elevating the stability and content of a sulfur-containing proanthocyanidine oligomer which has almost not been examined conventionally, or a method for producing the same. SOLUTION: This preparation for external use obtained by elevating the stability and content of the sulfur-containing proanthocyanidine oligomer is provided by blending a polyhydric alcohol in the preparation for external use containing the sulfur-containing proanthocyanidine oligomer for showing that the sulfur-containing proanthocyanidine oligomer which is an active ingredient, shows a good stability for a long period in the preparation, and also improving the solubility of the sulfur-containing proanthocyanidine oligomer by blending the polyhydric alcohol to increase the content of the sulfur-containing proanthocyanidine oligomer in the preparation, and the method for producing the same is also provided. COPYRIGHT: (C)2008,JPO&INPIT
    • 要解决的问题:提供通过提高几乎未经常规检查的含硫原花色素寡聚物的稳定性和含量而获得的外部用途制剂或其制备方法。 解决方案:通过提高含硫原花色素低聚物的稳定性和含量而获得的这种外用制剂是通过在含有含硫原花色素低聚物的外用制剂中混合多元醇来提供的, 含有原花青素低聚物作为活性成分,在制备中长时间显示出良好的稳定性,并且还通过混合多元醇来提高含硫原花青素低聚物的溶解度,从而提高含硫原花色素低聚物的含量 还提供了制备方法及其制备方法。 版权所有(C)2008,JPO&INPIT