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1. 发明专利

JP2014151137A Deodorant and uses of the same 审中-公开
标题翻译：除臭剂及其用途
公开(公告)号：JP2014151137A
公开(公告)日：2014-08-25
申请号：JP2013026150
申请日：2013-02-14
申请人： Ichimaru Pharcos Co Ltd , 一丸ファルコス株式会社 , Jnc Corp , Jnc株式会社
发明人： FUJITA SACHIKO , TSUBOI MAKOTO
IPC分类号： A61L9/01 , A61K8/64 , A61Q15/00 , A61Q17/00 , A61Q19/10 , C11D3/37
摘要： PROBLEM TO BE SOLVED: To provide an inexpensive and extremely safe deodorant capable of specifically and significantly abating or eliminating body odors, above all unpleasant odors attributed to 2-nonenal known to contribute to aging-related odors; and a body detergent and a detergent or softener used for laundering shoes, garments, or beddings each including the deodorant.SOLUTION: The provided deodorant targeting 2-nonenal, namely a substance known to contribute mainly to ageing-related odors, includes ε-polylysine or salt thereof as an effective component; uses of the same based on applications thereof mainly to bodies, garments, beddings, and furniture and uses of the same for detergents or softeners used for laundering shoes, garments, or beddings are also proposed.
摘要翻译：要解决的问题：提供一种廉价且极其安全的除臭剂，能够特异性和显着地减轻或消除身体气味，首先是归因于已知有助于老化相关气味的2-壬烯醛的令人不愉快的气味; 以及用于洗涤鞋子，衣物或各种包含除臭剂的床上用品的洗涤剂和洗涤剂或柔软剂。解决方案：所提供的针对2-壬烯醛的除臭剂即已知主要对老化有关的气味有贡献的物质包括 - 聚赖氨酸或其盐作为有效成分; 还提出了基于其应用的用途，主要涉及身体，衣服，床上用品和家具，以及其用于洗涤鞋，衣服或床上用品的洗涤剂或软化剂的用途。

2. 发明专利

JP2013241382A Fibroblast migration promoter 审中-公开
标题翻译： FIBROBLAST MIGRATION PROMOTER
公开(公告)号：JP2013241382A
公开(公告)日：2013-12-05
申请号：JP2012117083
申请日：2012-05-23
申请人： Ichimaru Pharcos Co Ltd , 一丸ファルコス株式会社 , Univ Of Miyazaki , 国立大学法人宮崎大学
发明人： TSUBOI MAKOTO , YAMAGUCHI MASATOSHI , MADHYASTHA HARISHKUMAR , SAMEJIMA HIROSHI
IPC分类号： A61K36/75 , A61K8/97 , A61P17/02 , A61P43/00 , A61Q19/00
摘要： PROBLEM TO BE SOLVED: To provide a fibroblast migration promoter which is useful for novel and quick healing of a wound, or an external preparation composition or a pharmaceutical composition for healing a wound.SOLUTION: This invention relates to: a fibroblast migration promoter containing a natural and safe plant: Citrus Tamurana form Orange Hyuganatu extract as an active ingredient; or an external preparation composition or a pharmaceutical composition containing the fibroblast migration promoter. The fibroblast migration promoter preferably contains a fraction having a molecular weight of 2,000-200,000 obtained by gel filtration chromatography from the Citrus Tamurana form Orange Hyuganatu extract as an active ingredient.
摘要翻译：要解决的问题：提供可用于伤口的新颖和快速愈合的成纤维细胞迁移促进剂，或用于治愈伤口的外用制剂组合物或药物组合物。解决方案：本发明涉及：含有天然和安全的植物：柑橘类Tamurana形式橙色Hyuganatu提取物作为活性成分; 或外用制剂组合物或含有成纤维细胞迁移促进剂的药物组合物。成纤维细胞迁移促进剂优选含有通过凝胶过滤色谱法从柑橘属植物橙色Hyuganatu提取物中获得的分子量为2,000-200,000的级分作为活性成分。

3. 发明专利

JP2013129633A Composition for oral cavity 有权
标题翻译：口腔用组合物
公开(公告)号：JP2013129633A
公开(公告)日：2013-07-04
申请号：JP2011280670
申请日：2011-12-22
申请人： Ichimaru Pharcos Co Ltd , 一丸ファルコス株式会社
发明人： TANAKA KIYOTAKA
IPC分类号： A61K8/97 , A61K36/18 , A61K36/28 , A61K38/00 , A61P1/02 , A61P31/04 , A61P31/10 , A61Q11/00
摘要： PROBLEM TO BE SOLVED: To provide a novel depressant for periodontal disease bacteria, a novel candida depressant, and a novel composition for an oral cavity useful for prevention of oral cavity diseases in the aging society.SOLUTION: It is found that extracts of specific plants (Azadirachta indica extract, Cynara scolymus extract, and Sapindus Trifoliatus extract) or proteoglycan have excellent periodontal disease bacteria depressant effects. The extracts of Azadirachta indica, Cynara scolymus, and Sapindus Trifoliatus also have depressant effects to candida. Thus, the novel depressant for periodontal disease bacteria, the novel candida depressant, and the novel composition for an oral cavity are provided.
摘要翻译：要解决的问题：为牙周病细菌，新颖的念珠菌抑制剂以及用于预防老年社会口腔疾病的口腔新型组合物提供新型抑制剂。解决方案：发现特定植物提取物（Azadirachta indica提取物，Cynara scolymus提取物和Sapindus Trifoliatus提取物）或蛋白多糖具有优异的牙周病细菌抑制作用。 Azadirachta indica，Cynara scolymus和Sapindus Trifoliatus的提取物也对念珠菌具有抑制作用。因此，提供了用于牙周病的新型抑制剂，新颖的念珠菌抑制剂和口腔用新型组合物。

4. 发明专利

JP2012219092A Kinesin inhibitor 有权
标题翻译：金氏抑制剂
公开(公告)号：JP2012219092A
公开(公告)日：2012-11-12
申请号：JP2011090254
申请日：2011-04-14
申请人： Ichimaru Pharcos Co Ltd , 一丸ファルコス株式会社
发明人： TANAKA KIYOTAKA
IPC分类号： A61K8/97 , A23L1/30 , A61K36/53 , A61P17/00 , A61Q19/02
摘要： PROBLEM TO BE SOLVED: To provide a new and useful kinesin inhibitor; and to provide a composition which is useful for easing, preventing or improving various pigmentation symptoms such as a skin blemish and a freckle.SOLUTION: The kinesin inhibitor includes, as an active ingredient, a wild thyme extract. A pigmentation inhibitor is based on kinesin-inhibiting action. In addition, various compositions (medicinal drug compositions, food compositions and cosmetic compositions) contain the kinesin inhibitor.
摘要翻译：要解决的问题：提供一种新的有用的驱动蛋白抑制剂; 并提供可用于缓解，预防或改善各种色素沉着症状如皮肤瑕疵和雀斑的组合物。解决方案：驱动蛋白抑制剂包括作为活性成分的野生百里香提取物。色素沉着抑制剂是基于驱动蛋白抑制作用的。此外，各种组合物（医药组合物，食品组合物和化妆品组合物）含有驱动蛋白抑制剂。版权所有（C）2013，JPO＆INPIT

5. 发明专利

JP2012051908A Trypsin inhibitor 审中-公开
标题翻译： TRYPSIN抑制剂
公开(公告)号：JP2012051908A
公开(公告)日：2012-03-15
申请号：JP2011220649
申请日：2011-10-05
申请人： Ichimaru Pharcos Co Ltd , 一丸ファルコス株式会社
发明人： FURUKAWA MASAYO , TANAKA KIYOTAKA , ARUNASIRI IDDAMALGODA
IPC分类号： A61K36/53 , A61K8/97 , A61P1/18 , A61P7/02 , A61P17/00 , A61P43/00 , A61Q19/00
摘要： PROBLEM TO BE SOLVED: To provide a novel trypsin inhibitor containing a specific plant extract.SOLUTION: The trypsin inhibitor contains a dead nettle extract. The nettle extract is obtained by extracting a properly cut or pulverized flower, stem or leaf of Lamium album L. by use of a solvent. The trypsin inhibitor has a superior trypsin inhibiting effect and is useful for effectively preventing or improving pancreatic inflammation and clot formation, and dermal inflammation or diaper rash around excretory organs, or the like.
摘要翻译：要解决的问题：提供含有特定植物提取物的新型胰蛋白酶抑制剂。
解决方案：胰蛋白酶抑制剂含有死荨麻提取物。荨麻提取物通过使用溶剂萃取适当切割或粉碎的Lamium album L.的花，茎或叶来获得。胰蛋白酶抑制剂具有优异的胰蛋白酶抑制作用，可用于有效预防或改善胰腺炎症和血块形成，以及排泄器周围的真皮炎症或尿布疹等。版权所有（C）2012，JPO＆INPIT

6. 发明专利

JP2010209012A Ph-responsive liposome 有权
标题翻译： PH响应脂肪
公开(公告)号：JP2010209012A
公开(公告)日：2010-09-24
申请号：JP2009058063
申请日：2009-03-11
申请人： Bionanosheeter Co Ltd , Ichimaru Pharcos Co Ltd , 一丸ファルコス株式会社 , 株式会社バイオナノシータ
发明人： TAKEOKA SHINJI , OBATA YOSUKE , NAKAGAWA SATOSHI , OTSUBO SHINYA , KAWASAKI YUJI
IPC分类号： A61K9/127 , A61K47/12 , A61K47/18 , A61K47/28 , A61K47/34 , A61K47/42
CPC分类号： A61K9/1271
摘要： PROBLEM TO BE SOLVED: To provide a pH-responsive liposome holding an objective substance under an acidic pH environment and releasing the objective substance under a basic pH environment. SOLUTION: The pH-responsive liposome is provided by containing a cationic amphiphatic molecule and at least one of an anionic amphiphatic molecule and ampholytic amphiphatic molecule as constituting lipids, and on dispersing it in an aqueous medium, having a positive zeta potential under an acidic environment of COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供在酸性pH环境下保持目标物质的pH响应性脂质体，并在碱性pH环境下释放目标物质。解决方案：通过含有阳离子两亲分子和阴离子两亲性分子和两性两性两性分子中的至少一个作为构成脂质，并将其分散在水性介质中，具有下面的正ζ电位来提供pH响应型脂质体分散体的pH值为6.5的酸性环境，并且在分散体的≥pH8.5的碱性环境下也具有负ζ电位。版权所有（C）2010，JPO＆INPIT

7. 发明专利

JP2010195696A PREPARATION FOR ACTIVATING Akt-mTOR-p70S6K OF MUSCLE STRENGTHENING SYSTEM AND METHOD THEREOF 审中-公开
标题翻译：用于激活肌肉强化系统的Akt-mTOR-p70S6K的制备及其方法
公开(公告)号：JP2010195696A
公开(公告)日：2010-09-09
申请号：JP2009040149
申请日：2009-02-24
申请人： Ichimaru Pharcos Co Ltd , 一丸ファルコス株式会社
发明人： TSUBOI MAKOTO , TANAKA TOMOKA , ITO KENICHI
IPC分类号： A61K36/18 , A61K36/42 , A61K36/70 , A61K36/73 , A61P21/06 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a method of activating Akt-mTOR-p70S6K signaling in muscles to strengthen muscles and prevent muscular atrophy. SOLUTION: The method of activating the muscle strengthening reaction of Akt-mTOR-p70S6K comprises internally or externally applying a preparation having at least one extract selected from an extract of Boesenbergia pandurata, an extract of Alpinia katsumadai, an extract of Catalpa ovata G. Don., an extract of Polygonum bistorta, an extract of Rubus chingii, an extract of Salix alba L., and an extract of Trichosanthes kirilowii as an active ingredient to a human body. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供在肌肉中激活Akt-mTOR-p70S6K信号传导的方法以加强肌肉并防止肌肉萎缩。解决方案：激活Akt-mTOR-p70S6K的肌肉强化反应的方法包括内部或外部施用具有至少一种提取物的制剂，所述提取物选自以下的提取物：Boesenbergia pandurata，Alpinia katsumadai的提取物，Catalpa ovata的提取物茯苓，枸杞提取物，芦荟提取物，柳枝稷提取物，茯苓提取物作为人体的活性成分。版权所有（C）2010，JPO＆INPIT

8. 发明专利

JP2010083838A Adiponectin production promoter 审中-公开
标题翻译： ADIPONECTIN生产促销商
公开(公告)号：JP2010083838A
公开(公告)日：2010-04-15
申请号：JP2008257104
申请日：2008-10-02
申请人： Gifu Prefecture , Gifu Prefecture Kenkyu Kaihatsu Zaidan , Ichimaru Pharcos Co Ltd , Munekazu Iinuma , 一丸ファルコス株式会社 , 岐阜県 , 財団法人岐阜県研究開発財団 , 宗和飯沼
发明人： TSUBOI MAKOTO , OGUCHI KENJI , AKAO YUKIHIRO , IINUMA MUNEKAZU , MATSUMOTO KENJI , YOKOYAMA SHINICHIRO
IPC分类号： A61K36/18 , A23L1/30 , A23L2/52 , A61K8/97 , A61P3/00 , A61P3/04 , A61P3/10 , A61P9/10 , A61P43/00 , A61Q19/00
摘要： PROBLEM TO BE SOLVED: To provide a highly safe and economical adiponectin production promoter which is stable even in prescription, and easily ingestible. SOLUTION: Prophylaxis of various diseases caused by hyposecretion of adiponectin, e.g. arteriosclerosis, obesity, diabetes, hypertension, or lipid metabolic disorder, or prophylaxis or amelioration of metabolic syndrome is carried out by using a persimmon or an extract therefrom as the adiponectin production promoter. Persimmon pericarp is cited as a preferred extraction site. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供高度安全和经济的脂联素生产促进剂，即使在处方中也是稳定的，并且容易摄取。解决方案：预防由脂联素分泌不足引起的各种疾病，例如动脉硬化，肥胖症，糖尿病，高血压或脂代谢紊乱，或代谢综合征的预防或改善是通过使用柿子或其提取物作为脂联素生产促进剂进行的。柿果皮被引用为优选的提取位点。版权所有（C）2010，JPO＆INPIT

9. 发明专利

JP2008088185A Immunostimulant derived from silk protein hydrolysate 审中-公开
标题翻译：从SILK蛋白水解产物衍生的免疫球蛋白
公开(公告)号：JP2008088185A
公开(公告)日：2008-04-17
申请号：JP2007308112
申请日：2007-11-29
申请人： Gifu Prefecture , Ichimaru Pharcos Co Ltd , 一丸ファルコス株式会社 , 岐阜県
发明人： ANDO YOSHITAKA , WATANABE YUTAKA
IPC分类号： A61K38/00 , A23K1/16 , A23L1/30 , A61K8/64 , A61K8/98 , A61K35/64 , A61P9/10 , A61P31/04 , A61P35/00 , A61P37/00 , A61P37/04 , A61P37/08 , A61P39/06 , A61P43/00 , A61Q5/02 , A61Q5/12 , A61Q19/00 , A61Q19/08 , A61Q19/10
摘要： PROBLEM TO BE SOLVED: To provide an immunostimulant excellent in immunostimulating action, antioxidative effect and anticancer promotion action, and useful for maintenance of beautification and health. SOLUTION: The immunostimulant contains as an effective ingredient, a peptide obtained by hydrolyzing silk protein and having the molecular weight of 300-5,000. The immunostimulant is suitably applied to food and drink, cosmetics and pharmaceutical products. COPYRIGHT: (C)2008,JPO&INPIT

10. 发明专利

JP2007314483A Preparation for external use and method for producing the same 审中-公开
标题翻译：用于外部使用的制备及其生产方法
公开(公告)号：JP2007314483A
公开(公告)日：2007-12-06
申请号：JP2006148002
申请日：2006-05-29
申请人： Amino Up Chemical Co Ltd , Ichimaru Pharcos Co Ltd , 一丸ファルコス株式会社 , 株式会社アミノアップ化学
发明人： TSUBOI TAKAYUKI , KAWASAKI YUJI , WAKAMEI KOJI
IPC分类号： A61K8/49 , A61K8/34 , A61K8/97 , A61Q19/00
摘要： PROBLEM TO BE SOLVED: To provide a preparation for external use obtained by elevating the stability and content of a sulfur-containing proanthocyanidine oligomer which has almost not been examined conventionally, or a method for producing the same. SOLUTION: This preparation for external use obtained by elevating the stability and content of the sulfur-containing proanthocyanidine oligomer is provided by blending a polyhydric alcohol in the preparation for external use containing the sulfur-containing proanthocyanidine oligomer for showing that the sulfur-containing proanthocyanidine oligomer which is an active ingredient, shows a good stability for a long period in the preparation, and also improving the solubility of the sulfur-containing proanthocyanidine oligomer by blending the polyhydric alcohol to increase the content of the sulfur-containing proanthocyanidine oligomer in the preparation, and the method for producing the same is also provided. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供通过提高几乎未经常规检查的含硫原花色素寡聚物的稳定性和含量而获得的外部用途制剂或其制备方法。解决方案：通过提高含硫原花色素低聚物的稳定性和含量而获得的这种外用制剂是通过在含有含硫原花色素低聚物的外用制剂中混合多元醇来提供的，含有原花青素低聚物作为活性成分，在制备中长时间显示出良好的稳定性，并且还通过混合多元醇来提高含硫原花青素低聚物的溶解度，从而提高含硫原花色素低聚物的含量还提供了制备方法及其制备方法。版权所有（C）2008，JPO＆INPIT

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