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1. 发明专利

JPH0579682B2 失效
公开(公告)号：JPH0579682B2
公开(公告)日：1993-11-04
申请号：JP12729384
申请日：1984-06-22
申请人： TOKUYAMA SODA KK
发明人： ITO JUNICHI , HAYASHI TETSUO , SHIGETOMI YOSHUKI , MITANI KATSUO , ASAEDA EITARO
IPC分类号： C08F4/00 , C08F4/60 , C08F4/64 , C08F4/642 , C08F10/00

4. 发明专利

JPH0328446B2 失效
公开(公告)号：JPH0328446B2
公开(公告)日：1991-04-19
申请号：JP16753982
申请日：1982-09-28
申请人： TOKUYAMA SODA KK
发明人： MITANI KATSUO , KIMURA SHINICHI
IPC分类号： C08F14/00 , C08F2/00 , C08F2/04 , C08F2/06 , C08F2/34 , C08F14/02 , C08F14/06 , C08F214/06 , C08F293/00 , C08F297/00 , C08F297/06

7. 发明专利

JPH0215566B2 失效
公开(公告)号：JPH0215566B2
公开(公告)日：1990-04-12
申请号：JP2838885
申请日：1985-02-18
申请人： TOKUYAMA SODA KK
发明人： MITANI KATSUO , EDA YOSHITO , KIMURA SHINICHI , MAEHARA TAKASHI
IPC分类号： C08F8/00 , A61K38/00 , A61K39/00 , A61K47/00 , A61K47/32 , A61K47/48 , A61K49/00 , A61M1/36 , C07K16/00 , C07K17/08 , C08F8/14 , C08F8/32 , C08F8/34 , G01N33/545

9. 发明专利

JPS6329249A LATEX REAGENT 失效
公开(公告)号：JPS6329249A
公开(公告)日：1988-02-06
申请号：JP17187586
申请日：1986-07-23
申请人： TOKUYAMA SODA KK
发明人： KIMURA SHINICHI , MITANI KATSUO , EDA YOSHITO
IPC分类号： G01N33/545
摘要： PURPOSE:To obtain a reagent having excellent preservable stability by forming a latex reagent constituted by sensitizing an immune material to latex particles in such a manner said reagent has the average particle size of a prescribed range and that the ratio between the average particle size thereof and the average particle size of the latex particles attain the value of a specified range. CONSTITUTION:The average particle size of the latex particles to be used is not particularly limited and the latex particles having the average particle size ranging 0.05-0.38, more preferably 0.07-0.3mu are particularly adequate; further, the reproducibility is better with the particles having the smaller dispersion value of the particle sizes. The latex reagent is obtd. by sensitizing the immune active material with the latex particles. This reagent is required to have the average particle size D ranging; for example, 0.1-0.5mum. The ratio D/d of the average D of the particle of the reagent to the average particle size (d) of the latex particles is required to be in; for example, 1.3-3.0 range. The reagent has the high preservable stability but hardly detects the antigen of a low concn. if D/d is

10. 发明专利

JPS61189300A PRODUCTION OF HYDROPHILIC POLYMER PARTICLE 失效
公开(公告)号：JPS61189300A
公开(公告)日：1986-08-22
申请号：JP2838885
申请日：1985-02-18
申请人： TOKUYAMA SODA KK
发明人： MITANI KATSUO , EDA YOSHITO , KIMURA SHINICHI , MAEHARA TAKASHI
IPC分类号： C08F8/00 , A61K38/00 , A61K39/00 , A61K47/00 , A61K47/32 , A61K47/48 , A61K49/00 , A61M1/36 , C07K16/00 , C07K17/08 , C08F8/14 , C08F8/32 , C08F8/34 , G01N33/545
摘要： PURPOSE:To obtain the titled particle having excellent dispersion stability in aqueous medium, capable of immobilizing enzymes, proteins, immunoactive substances, etc., and suitable as a diagnostic reagent, by reacting a polymer particle having epoxy group at the surface with an organic compound having a specific group. CONSTITUTION:(A) A polymer particle having epoxy group on the surface [e.g. glycidyl (meth)acrylate (co)polymer] is made to react with (B) an organic compound having preferably plural functional groups reactive with epoxy group (preferably amino group, mercapto group, etc.) and hydroxyl groups in the molecule (e.g. 3-mercapto-1,2-propanediol) to obtain the objective particle. The average particle diameter of the polymer particle used as a raw material is preferably 0.05-10mu.

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