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1. 发明专利

JP2011196978A Measuring chip for surface plasmon resonance sensor 审中-公开
标题翻译：表面等离子体共振传感器的测量芯片
公开(公告)号：JP2011196978A
公开(公告)日：2011-10-06
申请号：JP2010067442
申请日：2010-03-24
申请人： Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社
发明人： MATSUMOTO TAKAYUKI
IPC分类号： G01N33/543 , G01N21/27 , G01N33/553
摘要： PROBLEM TO BE SOLVED: To accelerate fixation of a specimen to a measuring chip and to enhance detection sensitivity by obstructing non-specific adsorption, in the measurement of surface plasmon resonance.SOLUTION: The metal membrane formed on a substrate, the layer of a first fixing agent provided in order to fix a target molecule on the metal membrane which is constituted of a compound having the region bonded to a metal and a second fixing agent, and that of a second fixing agent which has a functional group bondable to a target and an alkylene glycol chain for obstructing non-specific adsorption, are formed to the measuring chip for the surface plasmon resonance sensor.
摘要翻译：要解决的问题：在测量表面等离子体共振中，加速样品固定在测量片上，并通过阻碍非特异性吸附来提高检测灵敏度。解决方案：金属膜形成在基片上，第一层为了将靶分子固定在由具有与金属键合的区域的化合物和第二固定剂构成的金属膜上而提供的固定剂，以及具有可与靶标连接的官能团的第二固定剂，形成用于阻止非特异性吸附的亚烷基二醇链，用于表面等离子体共振传感器的测量芯片。

2. 发明专利

JP2014210845A 糖鎖捕捉用粒子の製造に用いられるポリマー粒子および糖鎖捕捉用粒子审中-公开
标题翻译：用于生产糖链捕集颗粒的聚合物颗粒和糖链捕集颗粒
公开(公告)号：JP2014210845A
公开(公告)日：2014-11-13
申请号：JP2013086946
申请日：2013-04-17
申请人：住友ベークライト株式会社 , Sumitomo Bakelite Co Ltd
发明人： MATSUMOTO TAKAYUKI
IPC分类号： C08F220/04 , C08F8/30
CPC分类号： C08F8/30
摘要：【課題】糖鎖捕捉用粒子の製造に用いられるポリマー粒子であって、糖鎖捕捉用粒子を得るための反応ステップを少なくすることにより、糖鎖捕捉用粒子の製造方法を簡略化することができるポリマー粒子および糖鎖捕捉用粒子を提供する。【解決手段】糖鎖捕捉用粒子の製造に用いられるポリマー粒子であって、カルボキシル基を有する単量体と、架橋性単量体を重合して得られることを特徴とするポリマー粒子。また、前記ポリマー粒子は、カルボキシル基を有する単量体70mol%以上、99.99mol%以下と、架橋性単量体0.01mol%以上、30mol%以下を重合して得られるものであることが好ましい。【選択図】なし
摘要翻译：要解决的问题：提供用于制备糖链捕获颗粒的聚合物颗粒，其可以通过减少要进行的反应步骤的数量来简化制备糖链捕获颗粒的方法，以便获得糖链捕获颗粒，并提供糖链捕获颗粒。溶液：用于制备糖链捕获颗粒的聚合物颗粒通过聚合具有羧基的单体和可交联单体获得。聚合物粒子优选聚合70-99.99摩尔％的具有羧基的单体和0.01-30摩尔％的可交联单体。

3. 发明专利

JP2006258458A High molecular compound for medical material, and substrate for biochip using high molecular compound 审中-公开
标题翻译：用于医用材料的高分子化合物和使用高分子化合物的生物基质
公开(公告)号：JP2006258458A
公开(公告)日：2006-09-28
申请号：JP2005072862
申请日：2005-03-15
申请人： Somalogic Inc , Sumitomo Bakelite Co Ltd , ソマロジック,インコーポレイテッドSomaLogic, Inc. , 住友ベークライト株式会社
发明人： MATSUMOTO MITSUTAKA , SHIBAHARA SUMIO , MATSUMOTO TAKAYUKI , YOKOYAMA KANEHISA , FUNAOKA SOUHEI , MASUDA DAISUKE , COLEMAN MICHAEL PATRICK , ZICHI DOMINIC
IPC分类号： G01N33/545 , G01N33/53 , G01N33/543 , G01N33/547 , G01N37/00
CPC分类号： C08J7/047 , C08F220/28 , C08F220/30 , C08F220/36 , C08F220/38 , C08F2220/286 , C08F2220/306 , C08J2365/00 , C08J2443/00 , G01N33/54393 , Y10T428/31504 , Y10T428/31938
摘要： PROBLEM TO BE SOLVED: To provide a substrate for a biochip having high detection accuracy, capable of suppressing nonspecific adsorption/binding of a detection object material, when used for detection and analysis of a protein, a nucleic acid or the like. SOLUTION: This substrate for a biochip for immobilizing a physiologically active substance onto the surface of a solid phase substrate has on the substrate surface a layer including a high molecular compound acquired by copolymerizing an ethylene-based unsaturated polymeric monomer having an alkylene glycol residue, an ethylene-based unsaturated polymeric monomer having a functional group for immobilizing the physiologically active substance and an ethylene-based unsaturated polymeric monomer having a bridgeable functional group. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：待解决的问题：为了提供具有高检测精度的生物芯片用基板，能够抑制检测对象物质的非特异性吸附/结合，当用于检测和分析蛋白质，核酸等时。解决方案：用于将生理活性物质固定在固相基材表面上的生物芯片用基材在基材表面上具有包含通过使具有亚烷基二醇的乙烯类不饱和聚合单体共聚获得的高分子化合物的层残基，具有用于固定生理活性物质的官能团的乙烯类不饱和聚合单体和具有可桥接官能团的乙烯类不饱和聚合单体。版权所有（C）2006，JPO＆NCIPI

4. 发明专利

JP2014105308A Method for manufacturing polymer particles including hydrazide groups/oxylamino groups 有权
标题翻译：制备包含氢化物组合物的聚合物颗粒的方法/ OXYLAMINO组
公开(公告)号：JP2014105308A
公开(公告)日：2014-06-09
申请号：JP2012261091
申请日：2012-11-29
申请人： Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社
发明人： MATSUMOTO TAKAYUKI
IPC分类号： C08F2/22 , C08F22/22 , C08F22/38
摘要： PROBLEM TO BE SOLVED: To provide a method for manufacturing polymer particles including hydrazide groups or oxylamino groups capable of improving the yield of polymer particles.SOLUTION: One embodiment provides a method for manufacturing polymer particles including hydrazide groups or oxylamino groups where (C) polymer particles are obtained by polymerizing, with (B) a crosslinking agent within a w/o-type emulsion, (A1) a carboxylic acid ester monomer including a polymerizable group or (A2) a monomer including a polymerizable group and a hydrazyl groups or oxylamino groups protected by a protective group [P].
摘要翻译：要解决的问题：提供一种制造具有能够提高聚合物颗粒的收率的酰肼基或氧基氨基的聚合物颗粒的方法。解决方案：一个实施方案提供了制备包含酰肼基或氧基氨基的聚合物颗粒的方法，其中（C）聚合物通过与（B）交联剂在aw / o型乳液中聚合，（A1）包含可聚合基团的羧酸酯单体或（A2）包含可聚合基团和腙基或氧基氨基的单体受保护组[P]保护。

5. 发明专利

JP2013167614A Method of producing sugar chain array 审中-公开
标题翻译：生产糖链阵列的方法
公开(公告)号：JP2013167614A
公开(公告)日：2013-08-29
申请号：JP2012032634
申请日：2012-02-17
申请人： Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社
发明人： MATSUMOTO TAKAYUKI
IPC分类号： G01N33/53 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a method of producing a sugar chain array whereby fluorescence dye including rhodamine, as a grid marker, is used as a grid marker, in which a contamination due to fluorescence dye can be removed.SOLUTION: A solution including an anionic surfactant is used for cleaning a sugar chain on a substrate, so that such a contamination caused by a bond between fluorescence dye and glycosaminoglycan can be effectively removed.
摘要翻译：要解决的问题：提供一种制备糖链阵列的方法，其中使用包含罗丹明作为网格标记的荧光染料作为栅格标记，其中可以除去由荧光染料引起的污染。解决方案：包括阴离子表面活性剂用于清洗基底上的糖链，从而可以有效地除去由荧光染料和糖胺聚糖之间的键所引起的污染。

6. 发明专利

JP2010126700A Polymeric compound for bioassay, and substrate for bioassay using the same 审中-公开
标题翻译：用于生物聚合的聚合物，以及使用它的生物体的底物
公开(公告)号：JP2010126700A
公开(公告)日：2010-06-10
申请号：JP2008305864
申请日：2008-12-01
申请人： Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社
发明人： MATSUMOTO TAKAYUKI , ENOKI HISAFUMI , OKUBO MASAYOSHI
IPC分类号： C08F297/00 , C09D133/14 , C09D143/02 , C09D153/00 , G01N33/543 , G01N33/545
摘要： PROBLEM TO BE SOLVED: To provide a polymeric compound for bioassays which is capable of controlling nonspecific adsorption or bonding of proteins without coating an adsorption inhibitor and a substrate for bioassays using the same.
SOLUTION: The polymeric compound for bioassays is a polymeric compound at least having a unit capable of controlling nonspecific adsorption of proteins and a unit with a hydrophobic group, and a block copolymer. Preferably, the main chain of the polymeric compound has a (meth)acryl skeleton.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于生物测定的聚合物，其能够控制蛋白质的非特异性吸附或结合，而不涂覆吸附抑制剂和使用其的生物测定的底物。解决方案：用于生物测定的聚合物化合物是至少具有能够控制蛋白质非特异性吸附的单元和具有疏水基团的单元的聚合物和嵌段共聚物。优选地，聚合物的主链具有（甲基）丙烯酸骨架。版权所有（C）2010，JPO＆INPIT

7. 发明专利

JP2008001794A Polymer compound for medical material and medical material using the same polymer compound 审中-公开
标题翻译：用于医用材料的聚合物化合物和使用该聚合物化合物的医用材料
公开(公告)号：JP2008001794A
公开(公告)日：2008-01-10
申请号：JP2006172424
申请日：2006-06-22
申请人： Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社
发明人： MATSUMOTO TAKAYUKI , FUKUNISHI MASAAKI , MATSUMOTO MITSUTAKA
IPC分类号： C08F290/06 , A61L31/00 , C09D133/04 , C09D143/04 , C09D155/00 , C09D157/10
摘要： PROBLEM TO BE SOLVED: To provide a polymer compound for medical materials excellent in fixing ability of a physiologically active substance, having little nonspecific absorption to proteins, scarcely causing dissolution and deterioration in a washing step and having chemical and physical stability. SOLUTION: The polymer compound for medical materials is a polymer containing recurring units derived from (a) an ethylenic unsaturated polymerizable monomer having an alkylene glycol residue and (b) an ethylenic unsaturated polymerizable monomer to which a functional group for fixing the physiologically active substance is bonded through an alkylene glycol residue, and chain length of the alkylene glycol residue of the ethylenic unsaturated polymerizable monomer (b) is longer than chain length of the alkylene glycol residue of the ethylenic unsaturated polymerizable monomer (a), and a reactive functional group is provided at at least one terminal of the copolymer. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种对蛋白质具有很少非特异性吸收的生理活性物质的定影能力优异的医疗材料用高分子化合物，几乎不引起溶解和洗涤步骤的劣化，并具有化学和物理稳定性。解决方案：用于医疗材料的高分子化合物是含有（a）具有亚烷基二醇残基的烯属不饱和可聚合单体和（b）用于固定生理学上的官能团的烯属不饱和可聚合单体的重复单元的聚合物活性物质通过亚烷基二醇残基键合，烯属不饱和可聚合单体（b）的亚烷基二醇残基的链长比烯属不饱和可聚合单体（a）的亚烷基二醇残基的链长长，官能团提供在共聚物的至少一个末端。版权所有（C）2008，JPO＆INPIT

8. 发明专利

JP2007326920A Polymeric compound for bioassay and base material for bioassay using the same 有权
标题翻译：用于生物传感器和基材的聚合物用于生物传感器
公开(公告)号：JP2007326920A
公开(公告)日：2007-12-20
申请号：JP2006157974
申请日：2006-06-07
申请人： Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社
发明人： MATSUMOTO TAKAYUKI , FUKUNISHI MASAAKI , KURAMOTO HIROMITSU , FUJIWARA KAZUHIKO , FUNAOKA SOUHEI
IPC分类号： C08F220/18 , C07K17/08 , C08F220/60 , C08F230/02 , C12M1/00 , G01N33/543 , G01N33/547 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a polymeric compound for bioassay which restrains the non-specific adsorption/linkage of detection objects without the coating of an adsorption inhibitor and which can immobilize sugar, sugar chain, glycopeptide, antibody and/or physiologically active substances having these, and to provide a base material using it.
SOLUTION: The polymeric compound for bioassay comprises at least a unit having a phosphorylcholine group, a unit having a hydrophobic group, and a unit having a primary amino group. Preferably the above primary amino group is an oxylamino group and/or a hydrazide group.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供用于生物测定的高分子化合物，其抑制检测对象的非特异性吸附/连接而不涂覆吸附抑制剂并且可以固定糖，糖链，糖肽，抗体和/或生理学上具有这些的活性物质，并提供使用它的基础材料。解决方案：用于生物测定的高分子化合物至少包含具有磷酸胆碱基团的单元，具有疏水基团的单元和具有伯氨基的单元。优选地，上述伯氨基是氧基氨基和/或酰肼基。版权所有（C）2008，JPO＆INPIT

9. 发明专利

JP2004292783A Transparent barrier film and substrates for display element using this 审中-公开
公开(公告)号：JP2004292783A
公开(公告)日：2004-10-21
申请号：JP2003195038
申请日：2003-07-10
申请人： Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社
发明人： MARUYAMA HIRONORI , EGUCHI TOSHIMASA , SUGIZAKI ATSUSHI , MATSUMOTO TAKAYUKI , MORIMOTO JUNPEI
IPC分类号： G02F1/1333 , C08J7/06
摘要： PROBLEM TO BE SOLVED: To provide a transparent film with oxygen barrier performance and water-vapor barrier performance both higher than those hitherto known, and with high acid resistance. SOLUTION: This transparent barrier film with water-vapor permeability of ≤0.1 g/m 2 /day and oxygen permeability of ≤0.1 cc/m 2 /day/atm is obtained by forming at least one layer of an acid resistant inorganic substance on a resin base material, where the inorganic substance layer preferably comprises, as the main component, an oxide or a nitride or an oxynitride or a halide containing at least one element from among W, Ta, Nb, Ti, Ce, B, Ni, Cr, Zr, Mo, Se, Sr and Y. COPYRIGHT: (C)2005,JPO&NCIPI

10. 发明专利

JP2014102194A High polymer and carrier having surface covered with high polymer 审中-公开
标题翻译：高聚合物和载体具有覆盖高分子聚合物的表面
公开(公告)号：JP2014102194A
公开(公告)日：2014-06-05
申请号：JP2012255308
申请日：2012-11-21
申请人： Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社
发明人： ABE HIROKI , MATSUMOTO TAKAYUKI
IPC分类号： G01N33/545
摘要： PROBLEM TO BE SOLVED: To provide a high polymer having excellent ability immobilizing a sugar chain, etc., high adhesion to a carrier, small non-specific absorption of protein, etc., and physical and chemical stability, and to provide a carrier having the high polymer immobilized on the surface and a composite carrier having a sugar chain, etc., immobilized with the high polymer.SOLUTION: A high polymer obtained by co-polymerizing an ethylene unsaturated polymeric monomer having a hydrophobic group and an ethylene unsaturated polymeric monomer having a functional group immobilizing a sugar chain, etc., or a high polymer obtained by co-polymerizing the monomers and an ethylene unsaturated polymeric monomer having a hydrophilic group has excellent ability immobilizing the sugar chain, etc., high adhesion to a carrier, small non-specific absorption of an object to be detected and physical and chemical stability such as hard dissolution in a cleaning process and the like. A carrier covered with the high polymer can be used for a biochip, etc..
摘要翻译：要解决的问题：提供一种具有优异的固定糖链等的能力的高分子，对载体的高粘合性，蛋白质的非特异性吸收性等，以及物理和化学稳定性，以及提供具有固定在表面上的高聚合物和具有固定有高聚物的糖链等的复合载体。溶液：通过将具有疏水基团的乙烯不饱和聚合单体和乙烯不饱和聚合单体共聚而获得的高分子具有固定糖链等的官能团或通过共聚单体和具有亲水基团的乙烯不饱和聚合单体获得的高分子聚合物具有优异的固定糖链等的能力，对载体的高附着力，要检测的物体的小的非特异性吸收以及诸如清洁过程中的硬溶解的物理和化学稳定性等。用聚合物覆盖的载体可用于生物芯片等。

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