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1. 发明专利

JP2012078365A Polymer compound for medical material, and biochip substrate 有权
标题翻译：用于医用材料和生物基质的聚合物化合物
公开(公告)号：JP2012078365A
公开(公告)日：2012-04-19
申请号：JP2011269343
申请日：2011-12-08
申请人： Somalogic Inc , Sumitomo Bakelite Co Ltd , ソマロジック,インコーポレイテッドSomaLogic, Inc. , 住友ベークライト株式会社
发明人： MATSUMOTO MITSUTAKA , SHIBAHARA SUMIO , MATSUMOTO TAKAYUKI , YOKOYAMA KANEHISA , FUNAOKA SOHEI , MASUDA DAISUKE , MICHAEL PATRICK COLEMAN , DOMINIQUE ZIECH
IPC分类号： G01N33/543
CPC分类号： C08J7/047 , C08F220/28 , C08F220/30 , C08F220/36 , C08F220/38 , C08F2220/286 , C08F2220/306 , C08J2365/00 , C08J2443/00 , G01N33/54393 , Y10T428/31504 , Y10T428/31938
摘要： PROBLEM TO BE SOLVED: To provide a biochip substrate having high detection accuracy by suppressing nonspecific adsorption and bonding of detection object substances when detecting and analyzing a protein, nucleic acid, and the like.SOLUTION: A physiological active substance is immobilized on a surface of a solid phase substrate in the biochip substrate. The biochip substrate includes a layer containing a polymer compound obtained by copolymerizing an ethylene based unsaturated polymerizable monomer having one ethylenic double bond and an alkylene glycol residue on a substrate surface, an ethylene based unsaturated polymerizable monomer having one ethylenic double bond and a functional group for immobilizing the physiological active substance, and an ethylene based unsaturated polymerizable monomer having one ethylenic double bond and a cross-linkable functional group.
摘要翻译：待解决的问题：通过在检测和分析蛋白质，核酸等时抑制检测对象物质的非特异性吸附和结合，提供具有高检测精度的生物芯片基板。解决方案：将生理活性物质固定在生物芯片衬底中的固相衬底的表面上。生物芯片基板包括含有通过在基材表面上共聚具有一个烯属双键的亚乙基不饱和可聚合单体和亚烷基二醇残基获得的聚合物化合物的层，具有一个烯属双键的乙烯基不饱和可聚合单体和用于固定生理活性物质和具有一个烯属双键和可交联官能团的乙烯基不饱和可聚合单体。版权所有（C）2012，JPO＆INPIT

2. 发明专利

JP2006258458A High molecular compound for medical material, and substrate for biochip using high molecular compound 审中-公开
标题翻译：用于医用材料的高分子化合物和使用高分子化合物的生物基质
公开(公告)号：JP2006258458A
公开(公告)日：2006-09-28
申请号：JP2005072862
申请日：2005-03-15
申请人： Somalogic Inc , Sumitomo Bakelite Co Ltd , ソマロジック,インコーポレイテッドSomaLogic, Inc. , 住友ベークライト株式会社
发明人： MATSUMOTO MITSUTAKA , SHIBAHARA SUMIO , MATSUMOTO TAKAYUKI , YOKOYAMA KANEHISA , FUNAOKA SOUHEI , MASUDA DAISUKE , COLEMAN MICHAEL PATRICK , ZICHI DOMINIC
IPC分类号： G01N33/545 , G01N33/53 , G01N33/543 , G01N33/547 , G01N37/00
CPC分类号： C08J7/047 , C08F220/28 , C08F220/30 , C08F220/36 , C08F220/38 , C08F2220/286 , C08F2220/306 , C08J2365/00 , C08J2443/00 , G01N33/54393 , Y10T428/31504 , Y10T428/31938
摘要： PROBLEM TO BE SOLVED: To provide a substrate for a biochip having high detection accuracy, capable of suppressing nonspecific adsorption/binding of a detection object material, when used for detection and analysis of a protein, a nucleic acid or the like. SOLUTION: This substrate for a biochip for immobilizing a physiologically active substance onto the surface of a solid phase substrate has on the substrate surface a layer including a high molecular compound acquired by copolymerizing an ethylene-based unsaturated polymeric monomer having an alkylene glycol residue, an ethylene-based unsaturated polymeric monomer having a functional group for immobilizing the physiologically active substance and an ethylene-based unsaturated polymeric monomer having a bridgeable functional group. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：待解决的问题：为了提供具有高检测精度的生物芯片用基板，能够抑制检测对象物质的非特异性吸附/结合，当用于检测和分析蛋白质，核酸等时。解决方案：用于将生理活性物质固定在固相基材表面上的生物芯片用基材在基材表面上具有包含通过使具有亚烷基二醇的乙烯类不饱和聚合单体共聚获得的高分子化合物的层残基，具有用于固定生理活性物质的官能团的乙烯类不饱和聚合单体和具有可桥接官能团的乙烯类不饱和聚合单体。版权所有（C）2006，JPO＆NCIPI

3. 发明专利

JP2009229343A Immunochromatography measuring device 有权
标题翻译：免疫色谱测量装置
公开(公告)号：JP2009229343A
公开(公告)日：2009-10-08
申请号：JP2008077096
申请日：2008-03-25
申请人： Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社
发明人： MASUDA DAISUKE , FUKUSHIMA MASAO , ARAI SUSUMU
IPC分类号： G01N33/543
摘要： PROBLEM TO BE SOLVED: To provide an immunochromatography measuring instrument having no point at issue such as the lowering of detection sensitivity or the like.
SOLUTION: The immunochromatography measuring instrument contains a conjugate pad for holding a first substance which specifically reacts with an analyte and labelled with a labelling substance and an immunochromatography developing membrane and has a structure (a) wherein a developing liquid containing the analyte is directly introduced into the conjugate pad, a structure (b) wherein the conjugate pad and the immunochromatography developing membrane are separated from each other, and a structure (c) wherein a port is arranged so as to hold the developing liquid containing the analyte between the conjugate pad and the immunochromatography developing membrane.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供没有问题的免疫色谱测量仪器，例如降低检测灵敏度等。解决方案：免疫层析测量仪器包含用于保持与分析物特异性反应并用标记物质和免疫层析显影膜标记的第一物质的缀合物垫，并且具有（a）其中含有分析物的显影液体为直接引入到所述缀合物垫中的结构（b），其中所述缀合物垫和所述免疫色谱显影膜彼此分离，以及结构（c），其中端口被布置成将含有分析物的显影液保持在共轭垫和免疫层析显影膜。版权所有（C）2010，JPO＆INPIT

4. 发明专利

JP2006258630A Substrate for biochip, and manufacturing method of biochip 审中-公开
标题翻译：生物基质和生物化学品的制造方法
公开(公告)号：JP2006258630A
公开(公告)日：2006-09-28
申请号：JP2005076946
申请日：2005-03-17
申请人： Kazuhiko Ishihara , Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社 , 一彦石原
发明人： ISHIHARA KAZUHIKO , FUNAOKA SOUHEI , MASUDA DAISUKE , YOKOYAMA KANEHISA
IPC分类号： G01N33/53 , G01N33/543 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To manufacture a substrate for a biochip having high detection accuracy, capable of suppressing nonspecific adsorption or bonding of a detection object material without coating an adsorption prevention agent, when used for detection and analysis of a protein, a nucleic acid or the like.
SOLUTION: This manufacturing method of the substrate for the biochip wherein physiologically active substance capturing molecules are immobilized, which is used for detecting the physiologically active substance, includes a process for forming a layer including a polymer material having a phosphorylcholine group and an active ester group on the substrate surface, and a process for performing humidification processing of the layer including the polymer material.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：为了制造具有高检测精度的生物芯片用基板，能够抑制检测对象材料的非特异性吸附或接合而不涂覆吸附防止剂，当用于蛋白质的检测和分析时，核酸等。解决方案：用于检测生理活性物质的生物活性物质捕获分子固定化的生物芯片用基板的制造方法包括形成含有具有磷酸胆碱基的聚合物材料层和在基材表面上的活性酯基，以及对包含聚合物材料的层进行加湿处理的方法。版权所有（C）2006，JPO＆NCIPI

5. 发明专利

JP2011158406A Casing, casing kit, and specimen sampling kit 审中-公开
标题翻译：箱子，箱包和样品取样袋
公开(公告)号：JP2011158406A
公开(公告)日：2011-08-18
申请号：JP2010021706
申请日：2010-02-03
申请人： Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社
发明人： MASUDA DAISUKE , AKAMINE AKINORI , ARAI SUSUMU , FUKUSHIMA MASAO
IPC分类号： G01N1/00 , G01N1/28
摘要： PROBLEM TO BE SOLVED: To provide a casing which makes a specimen introduced from a specimen inlet speedily flow down toward the side of a determination window and to provide a casing kit and a specimen sampling kit. SOLUTION: The casing 2 constitutes the specimen sampling kit for analysis of a specimen liquid Q. The casing 2 includes a bottom body 3 and a lid body 4 fitted in the bottom body 3. The lid body 4 includes both of the specimen inlet 43 having a cylindrical cylinder part 46 into which the specimen is introduced and the determination window 44 for determining the presence or absence of an object to be analyzed in the specimen liquid Q. The cylinder part 46 includes: an inside protrusion part 463 protruding to the inside of the lid body 4; and a side-part opening part 464 is formed in circumferential part of the inside protrusion part 463. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供一种壳体，其使从样品入口引入的样本快速向下朝向确定窗口侧流动，并提供套管套件和样本采样套件。
解决方案：壳体2构成用于分析样品液体Q的样本取样组件。壳体2包括底部本体3和装配在底部本体3中的盖体4.盖体4包括两个样本入口43具有引入试样的圆柱形圆筒部分46和用于确定样品液体Q中待分析物体的存在或不存在的确定窗口44.圆筒部分46包括：突出到盖体4的内部; 并且侧部开口部464形成在内部突出部463的周向部分。版权所有（C）2011，JPO＆INPIT

6. 发明专利

JP2006250667A Substrate for biochip and biochip 有权
标题翻译：生物和生物学基础
公开(公告)号：JP2006250667A
公开(公告)日：2006-09-21
申请号：JP2005066609
申请日：2005-03-10
申请人： Kazuhiko Ishihara , Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社 , 一彦石原
发明人： ISHIHARA KAZUHIKO , FUNAOKA SOUHEI , MASUDA DAISUKE , YOKOYAMA KANEHISA
IPC分类号： G01N33/547 , C12M1/00 , G01N33/53 , G01N33/543 , G01N33/545 , G01N33/552 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a substrate for a biochip constituted so as to suppress the non-specific adsorption and bonding of a detection target substance when used in the detection and analysis of protein, nucleic acid or the like and high in detection precision.
SOLUTION: The substrate for the biochip is constituted so as to immobilize a physiologically active substance on the surface of a solid phase substrate and a layer containing a polymeric compound, which is obtained by copolymerizing a monomer having a phosphorylcholine group, a monomer having an active ester group and a monomer having a crosslinkable functional group, is provided on the surface of the substrate. By this constitution, the non-specific adsorption and bonding of the detection target substance are suppressed, the lowering of a signal due to the washing of a base material can be reduced and the substrate for the biochip high in detection precision can be obtained.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种用于生物芯片的基板，其构成为当用于检测和分析蛋白质，核酸等时检测目标物质的非特异性吸附和结合，检测精度。解决方案：生物芯片的基材构成为将生理活性物质固定在固相基材的表面和含有聚合物的层上，该层是通过使具有磷酰胆碱基团的单体，单体具有活性酯基和具有交联性官能团的单体。通过这种结构，可以抑制检测对象物质的非特异性吸附和接合，可以降低由于基材的洗涤引起的信号的下降，并且可以获得检测精度高的生物芯片用基板。版权所有（C）2006，JPO＆NCIPI

7. 发明专利

JP2011209107A Specimen sampling tool 审中-公开
标题翻译：样品采样工具
公开(公告)号：JP2011209107A
公开(公告)日：2011-10-20
申请号：JP2010076951
申请日：2010-03-30
申请人： Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社
发明人： HOSONO KOHEI , ARAI SUSUMU , MASUDA DAISUKE
IPC分类号： G01N1/10 , G01N33/48
摘要： PROBLEM TO BE SOLVED: To provide a specimen sampling tool safely sampling a specimen if the specimen such as an infectious material is sampled.SOLUTION: The specimen sampling tool used for sampling a liquid material contained in the specimen, comprising: a specimen sampling rod; and a specimen sampling container plug separated from the specimen sampling rod, has a structure in which the specimen sampling rod is penetrated through the plug when the specimen is sampled, and keeps, the specimen sampling rod accommodated in the plug until the specimen is sampled. A pollution by fingers is prevented by holding the specimen sampling rod when the specimen sampling tool is used for sampling the specimen.
摘要翻译：要解决的问题：提供样品采样工具，如果感染材料样本被采样，安全采样样品。解决方案：样品采样工具用于对样品中包含的液体材料进行取样，包括：样品取样棒; 从样本采样棒分离出的标本取样容器塞具有采样时样品采样杆穿过插塞的结构，并将样品取样棒容纳在插塞中，直到样品被取样为止。当样本采样工具用于取样时，通过保持样本取样杆来防止手指污染。

8. 发明专利

JP2010038797A Container for specimen picking and inspection kit 审中-公开
标题翻译：样品检验和检验包装容器
公开(公告)号：JP2010038797A
公开(公告)日：2010-02-18
申请号：JP2008203616
申请日：2008-08-06
申请人： Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社
发明人： MASUDA DAISUKE , AKAMINE AKINORI , FUKUSHIMA MASAO , ARAI SUSUMU
IPC分类号： G01N1/00 , G01N33/48 , G01N33/543
摘要： PROBLEM TO BE SOLVED: To provide a container for specimen picking and an inspection kit being in no danger of specimen liquid leaking to the exterior in preparing the specimen liquid and used to appropriately introduce the specimen liquid in proper quantities into a detection kit.
SOLUTION: This container for specimen picking used to extract a specimen and introduce it into the inspection kit, comprises a container body and a lid part, and is equipped with opening parts at least in an upper end part and a lower end part, respectively, of the container body. This container has a structure in which the lid part is capable of sealing up the interior of the container body with a specimen picking tool closely put through the opening part in the upper end part while having a structure in which the opening part in the lower end part is sealed up.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：为了提供用于样本采集的容器和在准备样品液体时没有将样品液体泄漏到外部的危险的检查套件，并且用于将适当量的样品液体适当地引入检测试剂盒。解决方案：用于抽取样本并将其引入检查套件的样本采集容器包括容器体和盖部分，并且至少在上端部和下端部分配备有开口部分别为容器主体。该容器具有这样的结构，其中，盖部能够利用紧贴在上端部的开口部的试样拾取工具来密封容器主体的内部，同时具有下端的开口部的结构部分密封。版权所有（C）2010，JPO＆INPIT

9. 发明专利

JP2009229342A Immunochromatography measuring kit 审中-公开
标题翻译：免疫印迹测量工具包
公开(公告)号：JP2009229342A
公开(公告)日：2009-10-08
申请号：JP2008077095
申请日：2008-03-25
申请人： Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社
发明人： MASUDA DAISUKE , FUKUSHIMA MASAO , ARAI SUSUMU
IPC分类号： G01N33/543 , G01N33/569
摘要： PROBLEM TO BE SOLVED: To provide an immunochromatography measuring kit capable of accurately and properly introducing a developing liquid into a membrane carrier and having no leak dangerousness of the developing liquid to the outside.
SOLUTION: The immunochromatography measuring kit is equipped with at least an extraction container which stores an extraction liquid for extracting a specimen, the membrane carrier for subjecting the developing liquid having extracted the specimen to chromatographic development, and a casing for housing the membrane carrier. A judging window capable of observing the membrane carrier is provided to the upper part of the casing. A substance for capturing the specimen is held to the membrane carrier at the lower position of the judging window. Then, an opening part for attaching the extraction container is provided to the upper part of the casing and the opening part, and the extraction container can be attached so as to hold airtightness.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种能够将显影液准确且适当地引入膜载体并且对显影液没有泄漏危险性的免疫色谱测定试剂盒。解决方案：免疫色谱测定试剂盒至少装备有用于提取样品的提取液的提取容器，用于使提取了样品的显影液进行色谱显影的膜载体，以及容纳膜的壳体载体能够观察膜载体的判断窗口被提供到壳体的上部。用于捕获样本的物质被保持在判断窗口的下部位置处的膜载体上。然后，将安装提取容器的开口部分设置在壳体的上部和开口部分上，并且提取容器可以被安装成保持气密性。版权所有（C）2010，JPO＆INPIT

10. 发明专利

JP2006299045A Polymer compound for medical material and substrate for biochip using same 审中-公开
标题翻译：用于医用材料的聚合物化合物和使用其的生物化学基质
公开(公告)号：JP2006299045A
公开(公告)日：2006-11-02
申请号：JP2005121708
申请日：2005-04-19
申请人： Sumitomo Bakelite Co Ltd , 住友ベークライト株式会社
发明人： MATSUMOTO TAKAYUKI , SHIBAHARA SUMIO , MATSUMOTO MITSUTAKA , FUNAOKA SOUHEI , MASUDA DAISUKE
IPC分类号： C08F299/00 , C08F220/28 , C08F290/06 , C12M1/00 , C12N15/09 , G01N33/53 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a polymer compound for medical material which is excellent in immobilizing performance for a physiologically active substance, has least nonspecific adsorption to a protein, least dissolution and degradation in a cleaning process, and has chemical and physical stability, and is capable of appropriately coating on a surface of a plastic substrate, and a substrate for biochip having a high SN ratio using the polymer compound. SOLUTION: The polymer compound for medical material is obtained by copolymerizing on the surface of the substrate an ethylenic unsaturated polymerizable monomer having an alkylene glycol residual group, an ethylenic unsaturated polymerizable monomer having a functional group for immobilizing the physiologically active substance and an ethylenic unsaturated polymerizable monomer having a hydrophobic unit. A substrate for biochip is prepared by forming a layer including the polymer compound for medical material. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：待解决的问题：为了提供对生理活性物质的固定性能优异的医疗材料用高分子化合物，对蛋白质的非特异性吸附，在洗涤过程中的溶解和降解最少，具有化学和物理性质稳定性，并且能够适当地涂覆在塑料基板的表面上，以及使用高分子化合物具有高SN比的生物芯片用基板。解决方案：医用材料用高分子化合物通过在基材表面上共聚有具有亚烷基二醇残基的烯属不饱和可聚合单体，具有用于固定生理活性物质的官能团的烯属不饱和可聚合单体和具有疏水单元的烯属不饱和可聚合单体。通过形成包含用于医疗材料的高分子化合物的层来制备生物芯片用基材。版权所有（C）2007，JPO＆INPIT

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