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1. 发明专利

JPH04632B2 失效
公开(公告)号：JPH04632B2
公开(公告)日：1992-01-08
申请号：JP11989082
申请日：1982-07-12
申请人： SEIKENKAI
发明人： HATA KOSEI , MARUOKA TOSHUKI
IPC分类号： A23C13/16 , A23C9/123 , A23L9/20 , A23L29/00 , A61K35/74 , A61K35/747 , A61P1/12 , C12N1/20 , C12R1/225
摘要： A novel Lactobacillus clearans, Lactobacillus sulfurica and Lactobacillus nitrosus:Which can decrease both Na 2 S.9H 2 0 and/or NH 3 when inoculated and cultured on:a medium comprising 5 g of meat extract, 5 g of peptone, 0.5 g of Na 2 S.9H 2 O, 5 g of glucose, 1 g of CaCO 3 , 0.5 ml of NH 3 (as 100% ammonia) and 1 liter of water (pH, neutral);which shows no growth acceleration action even when said bacteria is cultured on a medium comprising a Stephenson-Wetham medium (hereafter merely referred to as (S-W); KH 2 PO 4 1 g, MgSO 4 .7H 2 O 0.7 g, NaCl 1g, (NH 4 ) 2 HPO 4 4 g; FeSO 4 .7H 2 O 0.03 g, glucose 5 g) + vitamins (A: 900 IU, B 1 : 1 mg, B 2 : 1 mg, B 6 : 1 mg, B 12 : 5 gamma, nicotinamide: 1.6 mg, calcium pantothenate: 8 mg, C: 64 mg, D 2 : 120 IU) + casamino acid 1 g and 0.5 g of Na 2 S.9H 2 0 and/or 0.5 ml (100% conversion) of NH 3 are incorporated at the logarithmic growth phase; and;which has the following characteristics:gram-positive, rod, non-motile, catalase-negative, no reduction of nitrates, no decomposition of gelatin, no formation of indole or hydrogen sulfide, high ability of forming lactic acid from glucose and lactose, and growth being accelerated by the addition of acetic acid.

2. 发明专利

JPS51102356A 失效
公开(公告)号：JPS51102356A
公开(公告)日：1976-09-09
申请号：JP2776275
申请日：1975-03-05
申请人： SEIKENKAI
发明人： HATA KOSEI , HATA TADATSUGU , MARUOKA TOSHUKI
IPC分类号： C02F3/00 , A61L9/00 , A61L9/01 , A62D3/00 , A62D3/02 , C02F3/34 , C11D1/00

3. 发明专利

JPS6234731B2 失效
公开(公告)号：JPS6234731B2
公开(公告)日：1987-07-28
申请号：JP1922676
申请日：1976-02-23
申请人： SEIKENKAI
发明人： HATA KOSEI , HATA TADATSUGU , MARUOKA TOSHUKI
IPC分类号： C12N1/00 , A61K35/74 , A61K35/747 , A61P1/00 , A61P27/16 , A61P31/04
摘要： This invention comprising a single or plural strains of Lactobacillus having special characteristics that have been never known is a new type of pharmaceutical Lactobacillus preparation for the treatment of infectious diseases. Some of the characteristics of Lactobacillus used for the present invention as as follows. (a) They are able to grow in low nutrition. (b) The speed of multiplication is quick. (c) By odoriferous S-, N- & C-compound, is promoted the growth. The effects of the present invention are as follows. Unlike the antibiotics which serves only to kill the bacteria, the present preparation is characteristic in that (a) it is non-pathogenic; (b) it can produce antibiotics thereby killing bacteria; (c) it can survive in the growth competition with pathogenic or other bacteria; (d) it denatures the metabolites (including poisonous ones) of living bodies or convert them into constituents of its own cells; (e) it purifies an affected part; (f) it shows anti-inflammatory or anti-swelling activities; and finally (g), as said preparation is foreign to the living bodies and is non-pathogenic, it is at least digested after the inflammatory diseases disappear. Accordingly, the present invention can be used extensively to give better therapeutic effects, except where the physical structure does not permit to use it.

4. 发明专利

JPS5126280A KOBONO SEIZOHOHO 失效
公开(公告)号：JPS5126280A
公开(公告)日：1976-03-04
申请号：JP9685874
申请日：1974-08-22
申请人： SEIKENKAI
发明人： HATA KOSEI , HATA TADATSUGU
IPC分类号： C12N1/32 , C12R1/645 , C12R1/66

5. 发明专利

JPH0357745B2 失效
公开(公告)号：JPH0357745B2
公开(公告)日：1991-09-03
申请号：JP5262580
申请日：1980-04-21
申请人： SEIKENKAI
发明人： HATA KOSEI
IPC分类号： C02F3/34 , B01D17/00 , C12N1/20 , C12R1/38 , C12S1/00

6. 发明专利

JPS5154920A 失效
公开(公告)号：JPS5154920A
公开(公告)日：1976-05-14
申请号：JP12863574
申请日：1974-11-07
申请人： SEIKENKAI
发明人： HATA KOSEI , HATA TADATSUGU
IPC分类号： C12N1/00 , A61K35/74 , A61P13/02 , A61P15/00 , C12R1/01

7. 发明专利

JPS6236489B2 失效
公开(公告)号：JPS6236489B2
公开(公告)日：1987-08-07
申请号：JP450480
申请日：1980-01-21
申请人： SEIKENKAI
发明人： HATA KOSEI
IPC分类号： A61L9/01 , A01K1/00 , A01K13/00 , A23K10/12 , A23K10/18 , A23K20/00 , A61K8/00 , A61K8/23 , A61K8/36 , A61K8/40 , A61K8/44 , A61K8/46 , A61K8/99 , A61K35/74 , A61P43/00 , A61Q11/00 , A61Q15/00 , C02F11/00 , C12N1/20

8. 发明专利

JPS5173136A Funbenno datsushuhoho 失效
标题翻译： FUNBENNO DATSUSHUHOHO
公开(公告)号：JPS5173136A
公开(公告)日：1976-06-24
申请号：JP13477374
申请日：1974-11-20
申请人： Seikenkai
发明人： HATA KOSEI , HATA TADATSUGU
IPC分类号： C02F3/34 , A23K1/00 , A23K1/16 , A61L9/01 , C12N1/00 , C12N1/20

9. 发明专利

JPS511656A 失效
公开(公告)号：JPS511656A
公开(公告)日：1976-01-08
申请号：JP7442874
申请日：1974-06-29
申请人： SEIKENKAI
发明人： HATA KOSEI , HATA TADATSUGU
IPC分类号： A61K8/00 , A61K8/99 , A61Q11/00

10. 发明专利

JPS6018644B2 失效
公开(公告)号：JPS6018644B2
公开(公告)日：1985-05-11
申请号：JP12863574
申请日：1974-11-07
申请人： SEIKENKAI
发明人： HATA KOSEI , HATA TADATSUGU
IPC分类号： C12N1/00 , A61K35/74 , A61P13/02 , A61P15/00 , C12R1/01

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