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1. 发明专利

JP2006273760A RORα PROMOTING EXPRESSION INDUCEMENT OF BMAL1 审中-公开
标题翻译： RALalpha促进BMAL1的表达诱导
公开(公告)号：JP2006273760A
公开(公告)日：2006-10-12
申请号：JP2005096459
申请日：2005-03-29
申请人： Sony Corp , ソニー株式会社
发明人： YAMAMOTO TAKUO , MAMINE TAKAYOSHI , TAKUMI TORU , AKASHI MAKOTO
IPC分类号： C07K14/47 , A61K31/7088 , A61K31/7105 , A61K39/395 , A61K45/00 , A61K48/00 , A61P25/00 , A61P25/20 , A61P35/00 , C12M1/00 , C12N15/09 , C12Q1/02 , G01N33/15 , G01N33/50 , G01N33/53 , G01N33/566
CPC分类号： A61K31/7105 , A61K31/7088 , C07K14/4702 , C07K14/70567 , G01N33/743 , G01N2333/70567 , G01N2500/00
摘要： PROBLEM TO BE SOLVED: To elucidate unexplained parts of controlling mechanism of circadian rhythm.
SOLUTION: Promotion of expression inducement of Bmal1(brain-muscle ARNT-like protein 1) by RORα (retinoic acid receptor-related orphan receptor alpha) and promotion of expression inducement of Bmal1 in low oxygen state are newly found out. Existence of control mechanism of circadian rhythm that promotion of expression of RORα by the low oxygen state or the like promotes expression inducement of Bmal1 and the promotion of expression inducement of Bmal1 promotes bonding of Bmal1 with CLOCK and promotes expression inducement of Per gene or Cry gene, is much suggested thereby. So, application thereof as a jet lag conditioner or an anticancer agent is possible.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：阐明昼夜节律控制机制的不明原因。解决方案：新发现通过RORα（视黄酸受体相关孤儿受体α）促进Bmal1（脑 - 肌肉ARNT样蛋白1）的表达诱导和促进低氧状态下Bmal1的表达诱导。存在昼夜节律的控制机制，促进低氧状态等的RORα表达促进Bmal1的表达诱导，促进Bmal1的表达诱导促进Bmal1与CLOCK的结合，促进Per基因或Cry基因的表达诱导，因此被大量的建议。因此，作为喷射滞后调理剂或抗癌剂的应用是可能的。版权所有（C）2007，JPO＆INPIT

2. 发明专利

JP2005114371A Detection part for hybridization and other interaction, dna chip equipped therewith, and another substrate for bioassay 有权
标题翻译：用于杂交和其他相互作用的检测部分，其中提供的DNA芯片以及用于生物多样性的其他基材
公开(公告)号：JP2005114371A
公开(公告)日：2005-04-28
申请号：JP2003344861
申请日：2003-10-02
申请人： Sony Corp , Sony Internatl Europ Gmbh , ソニーインターナショナル (ヨーロッパ) ゲゼルシャフトミットベシュレンクテルハフツング , ソニー株式会社
发明人： SEGAWA YUJI , MAMINE TAKAYOSHI , HARNACK OLIVER
IPC分类号： G01N33/53 , B03C5/02 , C12M1/00 , C12M1/34 , C12N15/09 , G01N27/00 , G01N27/327 , G01N27/416 , G01N27/447 , G01N33/543 , G01N37/00
CPC分类号： B03C5/026
摘要： PROBLEM TO BE SOLVED: To freely perform the high-order structural adjustment, movement and fixation of a substance, the removal of an unnecessary substance or the like by providing two pairs of counter electrodes in a reaction region and applying a predetermined electric field thereto. SOLUTION: The substrate for bioassay has a detection part 1a for the interaction between substances for constituting a pair of first counter electrodes E 11 and E 12 opposedly arranged so as to put a reaction region 2 therebetween for providing an interaction place between substances and a pair of second counter electrodes E 21 and E 22 opposedly arranged in the axial direction Y crossing the opposed axis X of a pair of the first counter electrodes E 11 and E 12 and provided with both electrodes E 21 and E 22 or one electrode E 21 (E 22 ). COPYRIGHT: (C)2005,JPO&NCIPI
摘要翻译：要解决的问题：通过在反应区域中设置两对对电极来自由地执行物质的高阶结构调整，移动和固定，去除不需要的物质等，并施加预定的电领域。解决方案：用于生物测定的基板具有检测部1a，用于构成一对第一对置电极E 11 和E 12 的物质之间的相互作用，在其间设置反应区域2，以提供物质之间的相互作用位置和在轴向方向Y上相对布置的一对第二对向电极E SB SB 21和/ 一对第一对置电极E 11 和E 12 的X轴，并具有两个电极E 21 和E / SB>或一个电极E 21（E 22 ）。版权所有（C）2005，JPO＆NCIPI

3. 发明专利

JP2005030783A BIOCHEMICAL REACTION APPARATUS, SUBSTRATE FOR BIOCHEMICAL REACTION, MANUFACTURING METHOD OF SUBSTRATE FOR HYBRIDIZATION AND HYBRIDIZATION METHOD 审中-公开
公开(公告)号：JP2005030783A
公开(公告)日：2005-02-03
申请号：JP2003193064
申请日：2003-07-07
申请人： SONY CORP
发明人： NAKAO ISAMU , MAMINE TAKAYOSHI , YAMAMOTO MASANOBU , TAKEDA MINORU , FURUKI MOTOHIRO
IPC分类号： G01N33/53 , C12M1/00 , C12Q1/68 , G01N33/543 , G01N33/553 , G01N33/566 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a biochemical reaction apparatus capable of performing a biochemical reaction by using a substrate, the substrate for the biochemical reaction such as a DNA (deoxyribonucleic acid) chip, a hybridization method of hybridizing a nucleotide chain, and a biochemical reaction apparatus capable of performing hybridization at a high speed relative to a substrate manufacturing method for the hybridization wherein the nucleotide chain for a probe is immobilized. SOLUTION: As for the substrate 1 for bioassay, the main surface similar to an optical disk such as a CD has an annular flat shape. The substrate 1 is driven rotatively around a center hole 2, and the substrate 1 has the surface 1a on which a plurality of wells 8 are formed, which are fields for a hybridization reaction between a probe DNA (a nucleotide chain for detection) and a sample DNA (a target nucleotide chain). A transparent electrode film 4 is formed on the lower layer of the wells 8 on the substrate 1. At the hybridization time, an external electrode 18 is brought close from the upper surface 1a side of the substrate 1, and an alternating-current power is applied between the transparent electrode film 4 and the external electrode 18, to thereby give an alternating-current field in the vertical direction to the substrate 1. COPYRIGHT: (C)2005,JPO&NCIPI

4. 发明专利

JP2001237411A OPTOELECTRIC INTEGRATED CIRCUIT DEVICE 失效
公开(公告)号：JP2001237411A
公开(公告)日：2001-08-31
申请号：JP2000048965
申请日：2000-02-21
申请人： SONY CORP
发明人： HAYASHI YUTAKA , MAMINE TAKAYOSHI
IPC分类号： H01L21/822 , G02B6/122 , H01L27/04 , H01L27/15 , H01L31/02 , H01S5/026
摘要： PROBLEM TO BE SOLVED: To provide an optoelectric integrated circuit device which can prevent the clock skew, even the level of integration is increased, and is capable of processing signals at high speeds. SOLUTION: An electronic element layer 4, provided with electronic elements D, an electronic wiring layer 2 provided with electronic wirings W, a light guide surface 3, a plurality of light-emitting elements L1 and so on and a plurality of photodetecting elements P1 and so on are disposed on the same substrate 1, the electronic elements D and the electronic wirings W constitute circuit blocks B1 and so on the light-emitting elements are connected to an output part, and the photodetecting elements are connected to an input part. The light emitting elements and the photodetecting elements are coupled on the same light guide surface, the photodetecting elements couple signal light pulses intensity-modulated by signals and clock light pulses intensity-modulated by a clock frequency with the same light guide surface, and the photodetecting elements receive the clock light pulse to control the clock frequency and phase of the circuit blocks.

5. 发明专利

JPH04340735A SEMICONDUCTOR INTEGRATED CIRCUIT DEVICE 失效
公开(公告)号：JPH04340735A
公开(公告)日：1992-11-27
申请号：JP11271191
申请日：1991-05-17
申请人： SONY CORP
发明人： MAMINE TAKAYOSHI , FUJIMAKI YOSHITSUGU
IPC分类号： H01L21/66
摘要： PURPOSE:To easily check electric continuity of a semiconductor integrated circuit device. CONSTITUTION:From above the peripheral part or the peripheral edge part of a package 3 of a semiconductor integrated circuit device 1, contact holes 4 are formed on the surfaces of inner leads 5 corresponding with the respective outer leads 2. From the upper surface of the semiconductor integrated circuit device 1, electric continuity of leads can be easily checked.

6. 发明专利

JPS60229386A SEMICONDUCTOR DEVICE 失效
公开(公告)号：JPS60229386A
公开(公告)日：1985-11-14
申请号：JP8486884
申请日：1984-04-26
申请人： SONY CORP
发明人： MAMINE TAKAYOSHI , ODA TATSUJI , IMAI TOSHIHIRO
IPC分类号： H01L21/265 , H01S5/00 , H01S5/20
摘要： PURPOSE:To obtain a semiconductor laser diode having stable characteristics by forming a non-current region to a semiconductor by implanting at least one kind of ions of He, Be, Li and B. CONSTITUTION:An N type first clad layer 2, a P type or N type active layer 3, a P type clad layer 4 and a P type low resistivity cap layer 5 are shaped on an N type base body 1 through epitaxial growth in succession. A mask 7 is formed on the cap layer 5, and boron B is implanted in depth intruding to the thickness of one part of the second clad layer 4 from the upper section of the cap layer 5 to shape a non-current injecting region 21 having high resistance. The mask is removed, and electrodes 7, 8 are applied, thus obtaining a semiconductor laser diode having stable characteristics. He, Be, Li, etc. can be used besides B as implanting ions.

7. 发明专利

JPS5821434B2 失效
公开(公告)号：JPS5821434B2
公开(公告)日：1983-04-30
申请号：JP10971674
申请日：1974-09-24
申请人： SONY CORP
发明人： MATSUSHITA TAKESHI , MAMINE TAKAYOSHI
IPC分类号： H01L31/04

8. 发明专利

JPS5563869A SEMICONDUCTOR DEVICE 失效
公开(公告)号：JPS5563869A
公开(公告)日：1980-05-14
申请号：JP13803978
申请日：1978-11-09
申请人： SONY CORP
发明人： HAYASHI HISAO , MAMINE TAKAYOSHI , MATSUSHITA TAKESHI
IPC分类号： H01L29/80 , H01L21/337 , H01L29/167 , H01L29/74 , H01L29/808
摘要： PURPOSE:To raise the controllability and reproducibility of the lifetime of carriers and facilitate the control of temperature dependence, by providing iron, gold and/or platinum in a semiconductor layer to control the lifetime of carriers. CONSTITUTION:Iron ions are implanted at the rate of 1X10 cm into a GTO thyristor from its reverse side. The thyristor is then annealed at a temperature of 1000 deg.C under an atmosphere of nitrogen for 1 hour. A gold film is evaporated at a thickness of 600Angstrom on the reverse side and diffused at a temperature of 890 deg.C. The recovery time Trr of GCS with gold and iron diffused is almost constant independently of the diffusion time of the gold. The lifetime tau is affected by the gold in the main at low temperature but by the iron in the main at high temperature. Diffusing both iron and gold in a semiconductor device is preferable to flatten its forward voltage VF. Since plural kinds of killers are used, the control of the lifetime is facilitated.

9. 发明专利

JPS5416175A PRODUCTION OF SEMICONDUCTOR DEVICE 失效
公开(公告)号：JPS5416175A
公开(公告)日：1979-02-06
申请号：JP8135577
申请日：1977-07-07
申请人： SONY CORP
发明人： MATSUSHITA TAKESHI , MAMINE TAKAYOSHI , HAYASHI HISAO , NISHIYAMA KAZUO
IPC分类号： H01L21/322 , H01L21/265
摘要： PURPOSE:To reduce temperature dependency of life time by using iron as a life time killer for minority carriers, performing ion implantation to control concentration with good reproducibility and further controlling doping quantity and annealing temperature.

10. 发明专利

JP2010262667A Visualization method and visualization apparatus related to biological material information, and information storage medium 有权
标题翻译：与生物材料信息和信息存储介质相关的可视化方法和可视化装置
公开(公告)号：JP2010262667A
公开(公告)日：2010-11-18
申请号：JP2010153946
申请日：2010-07-06
申请人： Sony Corp , ソニー株式会社
发明人： YAMAMOTO TAKUO , MAMINE TAKAYOSHI , YAMADA TAKAYUKI
IPC分类号： G06F19/26
摘要： PROBLEM TO BE SOLVED: To facilitate understanding of interaction mechanisms and metabolic systems of biological materials. SOLUTION: In the method for visualizing information on biological materials such as genes or protein by automatically displaying the information on a computer display screen by use of a computer system, biological materials belonging to the same class and interaction relations among the biological materials are displayed on the same layer on the computer display screen. COPYRIGHT: (C)2011,JPO&INPIT

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