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1. 发明专利

JP2011147720A Bag for liquid and method of manufacturing the same 有权
标题翻译：用于液体的袋及其制造方法
公开(公告)号：JP2011147720A
公开(公告)日：2011-08-04
申请号：JP2010013253
申请日：2010-01-25
申请人： Mitsui Chemicals Inc , Otsuka Pharmaceut Factory Inc , 三井化学株式会社 , 株式会社大塚製薬工場
发明人： HITOMI MITSUO , SHIBA EIJI , MIHIRA KEITA , SUMIYOSHI NOBUAKI , DENPO TAKAYUKI , MORI HITOSHI , SHOJI HIDEO
IPC分类号： A61J1/10 , B65D30/10 , B65D33/38
摘要： PROBLEM TO BE SOLVED: To provide a bag for a liquid, restraining variation in the capacity of a head space after the liquid is injected by applying a point seal where a flexible film is locally stuck, and further simply changing the position of the point seal according to the capacity of the bag, and provide a method of manufacturing the same. SOLUTION: In the medical liquid bag 1, the point seal 18 where a pair of flexible films 5 are locally stuck is applied at a predetermined position along the longitudinal direction of a pair of vertical seals 7 on the inside of a storing chamber 2 spaced with a fixed clearance 19 from the inner edge 9 of each vertical seal 7 to thereby restrain the storing chamber 2 from being swollen when the medical liquid is stored in the storing chamber 2. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：为了提供液体袋，通过施加局部粘贴柔性膜的点密封来限制液体注入之后的顶部空间的容量的变化，并且进一步简单地改变位置根据袋的容量进行点密封，并提供其制造方法。解决方案：在药液袋1中，将一对柔性膜5局部粘贴的点密封18沿着一对垂直密封件7的长度方向的预定位置施加在储存室 2与每个垂直密封件7的内边缘9间隔开固定的间隙19，从而当医用液体储存在储存室2中时，可以抑制储存室2膨胀。（C）2011，JPO＆INPIT

2. 发明专利

JP2008132318A Manufacturing method of dissolved oxygen reducing liquid agent 有权
标题翻译：溶解氧氧化还原液的制造方法
公开(公告)号：JP2008132318A
公开(公告)日：2008-06-12
申请号：JP2007276807
申请日：2007-10-24
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： SUMIYOSHI NOBUAKI , TATEISHI ISAMU , MORI HITOSHI , MORIMOTO YASUSHI
IPC分类号： A61J1/10 , A61J1/00 , A61J3/00
摘要： PROBLEM TO BE SOLVED: To provide a manufacturing method of a liquid agent reduced in the amount of dissolved oxygen, hardly deteriorated by oxidation and excellent in stability with an elapse of time. SOLUTION: The dissolved oxygen reducing liquid agent is housed in a chemical liquid container comprising a plastic of which the oxygen permeability under the condition of a temperature of 25°C and humidity RH of 60% within 12 hr after steam or hot-water sterilization treatment is 200 cm 3 /m 2 *24h*atm or above and the oxygen permeability under the condition of a temperature of 25°C and humidity RH of 60% within 12 hr when the oxygen permeability is in a steady state, is 100 cm 3 /m 2 *24h*atm or below. After the container is hermetically sealed and subjected to steam or hot-water sterilization treatment, the chemical liquid container is preserved under an environment equipped with a deoxidation means until the oxygen permeability of the plastic reaches the steady state and the concentration of dissolved oxygen of the liquid agent is reduced to 2 ppm or below. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：为了提供减少溶解氧量的液体试剂的制造方法，几乎不会由于氧化而劣化，并且随着时间的流逝而具有优异的稳定性。溶解氧减压液体容纳在包含塑料的化学液体容器中，该容器在蒸汽或热蒸气之后的12小时内，在25℃的温度和湿度RH为60％的条件下具有氧气渗透性，水处理灭菌处理温度为25℃，湿度RH为60％的条件下的氧气渗透性为200cm 3 / SP 2 / 当氧气渗透率处于稳定状态时，在12小时内为100厘米/小时。在将容器密封并进行蒸汽或热水灭菌处理之后，将化学液容器在具有脱氧装置的环境下保存，直到塑料的透氧性达到稳定状态，并且溶解氧的浓度液剂降至2ppm以下。版权所有（C）2008，JPO＆INPIT

3. 发明专利

JP2005349033A Drainage bag for peritoneal dialysis 有权
标题翻译：排水袋用于腹膜透析
公开(公告)号：JP2005349033A
公开(公告)日：2005-12-22
申请号：JP2004174613
申请日：2004-06-11
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： MORI HITOSHI , TATEISHI ISAMU , KOBAYASHI MASARU
IPC分类号： A61J1/14 , A61M1/28
摘要： PROBLEM TO BE SOLVED: To provide a drainage bag for peritoneal dialysis, wherein the turbidity of drainage is correctly determined without depending on parameters such as a drainage capacity and existence of air bubbles or a space. SOLUTION: The drainage bag 10 for peritoneal dialysis comprises a flexible storage part 11 made of a transparent or translucent resin film 11a and a mouth members 12a, 12b. The storage part 11 includes: a large storage chamber 13 arranged at the upstream side of a drainage flowing direction x; a small storage chamber 14 with the smaller drainage capacity compared with the large storage chamber 13; and a flow limiting means (weir part 15) which is arranged between both the storage chambers and limits the amount of the drainage which flows into the small storage chamber 14. Thus, the swelling of the small storage chamber 14 is limited to be not more than a prescribed degree. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种用于腹膜透析的排水袋，其中排水的浊度被正确地确定，而不依赖于诸如排水能力和存在气泡或空间的参数。解决方案：用于腹膜透析的引流袋10包括由透明或半透明树脂膜11a和口部件12a，12b制成的柔性储存部分11。储存部11包括：设置在排水流动方向x的上游侧的大型收纳室13; 与大储存室13相比，具有较小排水能力的小储存室14; 以及设置在两个储藏室之间的限流装置（堰部15），限制了流入小储存室14的排水量。因此，小储存室14的膨胀被限制为不更多比规定的程度。版权所有（C）2006，JPO＆NCIPI

4. 发明专利

JP2010046190A Connecting nozzle, spout, and medicament container 审中-公开
标题翻译：连接喷嘴，喷头和药物容器
公开(公告)号：JP2010046190A
公开(公告)日：2010-03-04
申请号：JP2008211613
申请日：2008-08-20
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： INOUE FUJIO , MORI HITOSHI , FUJIMURA TAKASHI
IPC分类号： A61J1/10 , B65D33/38 , B65D47/36 , B65D51/22 , F16L41/08
摘要： PROBLEM TO BE SOLVED: To provide a connecting nozzle which suppresses falling-out of a tube without using a separate tool and regardless of the type of the tube and suppresses misuse of the kept medicament, and a spout and a medicament container equipped with it. SOLUTION: In the connecting nozzle 6, a cylindrical nozzle 28 is provided which has a nozzle penetrating hole 32 penetrating from one end to the other end and is inserted into an inner cavity of the tube. At least one bulging part 33 bulging radially outward is formed on the side surface of the nozzle 28. Since a plurality of cuts 36 cut in the nozzle 28 in the axial direction are formed on the bulging part 33, the diameter of the bulging part 33 is reduced by external force. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种连接喷嘴，其不使用单独的工具来抑制管的脱落，并且不管管的类型如何，并且抑制保持药物的误用，以及配备有喷嘴和药物容器用它。解决方案：在连接喷嘴6中，设置有一个圆柱形喷嘴28，其具有从一端穿透到另一端的喷嘴穿透孔32，并插入到管的内腔中。在喷嘴28的侧面形成有至少一个在径向上向外凸出的凸出部分33.由于在凸起部分33上形成有在喷嘴28上沿轴向方向切割的多个切口36，凸起部分33的直径被外力减少。版权所有（C）2010，JPO＆INPIT

5. 发明专利

JP2005335134A Multilayer film, its manufacturing method and container using multilayer film 有权
标题翻译：多层膜，其制造方法和使用多层膜的容器
公开(公告)号：JP2005335134A
公开(公告)日：2005-12-08
申请号：JP2004155061
申请日：2004-05-25
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： TATEISHI ISAMU , KONISHI KENJI , MORI HITOSHI
IPC分类号： B65D30/02 , A61J1/10 , B32B9/00 , B32B27/32 , B65D65/40
摘要： PROBLEM TO BE SOLVED: To provide a multilayer film with high barrier properties, its manufacturing method and a container using this multilayer film. SOLUTION: The multilayer film has a base film 16 laminated on the vapor deposition surface 12 of a transparent barrier film 11 with a vapor-deposited inorganic matter through a double layer film 13 consisting of an adhesive layer 14 with 3 to 20 μm thickness and a shock-absorbing layer 15 with not less than 10 μm thickness. The shock-absorbing layer 15 of the double layer film 13 is a layer arranged facing the base film 16 and using a polyethylene with 0.890 to 0.920 g/cm 3 density. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供具有高阻隔性的多层膜，其制造方法和使用该多层膜的容器。解决方案：多层膜具有通过双层膜13层压在具有气相沉积无机物的透明阻挡膜11的蒸镀面12上的基膜16，双层膜13由具有3〜20μm的粘合层14 厚度不小于10μm的冲击吸收层15。双层膜13的减震层15是与基膜16相对配置的层，使用0.890〜0.920g / cm 3的密度的聚乙烯。版权所有（C）2006，JPO＆NCIPI

6. 发明专利

JP2011212505A Housing body for medical liquid container and process for producing the same 有权
标题翻译：医用液体容器的容器及其制造方法
公开(公告)号：JP2011212505A
公开(公告)日：2011-10-27
申请号：JP2011172243
申请日：2011-08-05
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： TATEISHI ISAMU , MORI HITOSHI , MORIMOTO YASUSHI
IPC分类号： A61J1/10
CPC分类号： B32B27/32 , A61J1/10 , A61M2207/00 , Y10T428/1352 , Y10T428/1379 , Y10T428/1383
摘要： PROBLEM TO BE SOLVED: To provide a housing body for a medical liquid container which can highly suppress degradation of a medical liquid, growth of bacteria or the like associated with oxygen permeation while maintaining properties required for a plastic medical liquid container.SOLUTION: A medical liquid is packed and sealed in a plastic medical liquid container whose oxygen permeability (25°C, 60% RH) within 12 hours after treated by steam sterilization or hot water sterilization is 200 cm/m.24h.atm or higher and oxygen permeability (25°C, 60% RH) in a steady state is 100 cm/m.24h.atm or lower, and the plastic medical liquid container is treated by steam sterilization or hot water sterilization, and then housed and sealed in an outer bag having oxygen barrier property together with a deoxygenating agent.
摘要翻译：要解决的问题：提供一种用于医疗液体容器的壳体，其能够高度抑制药液的劣化，与氧渗透相关的细菌等的生长，同时保持塑料医用液体容器所需的性能。解决方案：医疗将液体包装并密封在通过蒸汽灭菌或热水灭菌处理后的12小时内的透氧度（25℃，60％RH）为200cm / m·24h·atm以上且透氧性的塑料医疗用液体容器（ 25℃，60％RH）为100cm / m·24h·atm以下，塑料医用液体容器通过蒸汽灭菌或热水灭菌处理，然后收容并密封在具有氧气阻隔性与脱氧剂一起。

7. 发明专利

JP2008132319A Chemical liquid housing member reduced in amount of dissolved oxygen 有权
标题翻译：化学液体成员减少了溶解氧的量
公开(公告)号：JP2008132319A
公开(公告)日：2008-06-12
申请号：JP2007276808
申请日：2007-10-24
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： SUMIYOSHI NOBUAKI , TATEISHI ISAMU , MORI HITOSHI , MORIMOTO YASUSHI
IPC分类号： A61J1/10 , A61J1/00 , A61J1/05 , A61J3/00 , A61K9/08 , A61K31/07 , A61K31/122 , A61K31/197 , A61K31/198 , A61K31/355 , A61K31/375 , A61K31/401 , A61K31/405 , A61K31/4172 , A61K31/4188 , A61K31/4415 , A61K31/455 , A61K31/51 , A61K31/525 , A61K31/59 , A61K31/7004 , A61K31/714 , A61K33/24 , A61P3/02
摘要： PROBLEM TO BE SOLVED: To provide a chemical liquid housing member which keeps a low amount of dissolved oxygen in a chemical liquid, hardly causes a deterioration due to oxidation and excellent in stability with an elapse of time. SOLUTION: The chemical liquid is housed in a chemical liquid container 10 comprising a plastic of which the oxygen permeability under the condition of a temperature of 25°C and humidity RH of 60% within 12 hr after steam or hot-water sterilization treatment is 200 cm 3 /m 2 *24h*atm or above and the oxygen permeability under the condition of a temperature of 25°C and humidity RH of 60% within 12 hr when the oxygen permeability is in a steady state, is 100 cm 3 /m 2 *24h*atm or below. After the container is hermetically sealed and subjected to steam or hot-water sterilization treatment, the chemical liquid container is preserved under an environment having a deoxidation means until the oxygen permeability of the plastic reaches the steady state to adjust the concentration of dissolved oxygen of the chemical liquid to 2 ppm or below. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：为了提供一种在化学液体中保持少量溶解氧的化学液体容纳构件，几乎不会由于氧化而导致劣化，并且随着时间的流逝具有优异的稳定性。解决方案：将化学液体容纳在化学液体容器10中，该药液容器10包括在蒸汽或热水灭菌后12小时内在25℃的温度和60％的湿度RH的条件下的氧气渗透性的塑料处理温度为25℃，湿度RH为60％的条件下的氧透过度为12cm×2h / m 2 / 当氧气渗透率处于稳定状态时，为100cm 3 /小时* 24小时* atm以下。在将容器密封并进行蒸汽或热水灭菌处理之后，将化学液容器在具有脱氧装置的环境下保存，直到塑料的透氧性达到稳定状态，以调节溶解氧的浓度化学液体至2 ppm以下。版权所有（C）2008，JPO＆INPIT

8. 发明专利

JP2014076861A Bag for liquid medicine 有权
标题翻译：液体药包
公开(公告)号：JP2014076861A
公开(公告)日：2014-05-01
申请号：JP2013254414
申请日：2013-12-09
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： INOUE FUJIO , MORI HITOSHI , FUJIMURA TAKASHI
IPC分类号： B65D33/00 , A61J1/00 , A61J1/14 , B65D81/30
摘要： PROBLEM TO BE SOLVED: To provide an inexpensive bag for liquid medicine capable of easily grasping an amount of the liquid medicine without impairing light-shielding properties.SOLUTION: A bag 1 for liquid medicine comprises: a bag body 2 having light-shielding properties and flexibility and for housing medical liquid with fluidity; and a pouring member 3 for pouring the medical liquid from the bag body 2. A strip-like hologram film 24 is affixed to a substantially center of a bag surface 12 in a width direction so as to extend from an upper side (the other side) to a lower side (one side).
摘要翻译：要解决的问题：提供一种廉价的液体药物袋，其能够容易地掌握液体药物的量而不损害遮光性。解决方案：液体药物袋1包括：具有遮光性的袋体2和灵活性和流动性住院医用液体; 以及用于将药液从袋体2倾倒的倾倒部件3.将带状全息膜24沿宽度方向固定在袋表面12的大致中央，从上侧（另一侧）到下侧（一侧）。

9. 发明专利

JP2009248973A Multilayer film, medical fluid bags and method for manufacturing the same, and method for sterilization of medical fluid bags 有权
标题翻译：多层薄膜，医用流体袋及其制造方法以及医用流体袋的灭菌方法
公开(公告)号：JP2009248973A
公开(公告)日：2009-10-29
申请号：JP2008095324
申请日：2008-04-01
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： TATEISHI ISAMU , MORI HITOSHI
IPC分类号： B65D81/32 , A61J1/10 , B65D30/02 , B65D65/40
CPC分类号： A61J1/10 , A61J1/2093 , B32B7/02 , B32B27/08 , B32B27/32 , B32B2270/00 , B32B2307/306 , B32B2307/412 , B32B2307/50 , B32B2307/546 , B32B2307/72 , B32B2439/80
摘要： PROBLEM TO BE SOLVED: To provide a multilayered film which exhibits excellent heat resistance and can keep flexibility and transparency even after high-temperature sterilization and which prevents adhesion to a cutter when forming a peripheral seal area or cutting away unnecessary parts, and to provide medical fluid bags using the film, a method for manufacturing the same, and a method for sterilization of the medical fluid bags. SOLUTION: The multilayer film comprises the first layer (outer layer) 1 which is made of, e.g., a mixture comprising 55 to 85 wt.% of a linear polyethylene (PE-L) having a DSC melting point of 120 to 125°C and a density of 0.930 to 0.937g/cm 3 and 15 to 45 wt.% of a propylene homopolymer having a DSC melting point of 160 to 165°C and the second to fifth layers (inner layers) 2 to 5 which are each made of PE-L. The second and fourth layers 2 and 4 have DSC melting points of 120 to 125°C and densities of 0.910 to 0.920g/cm 3 , while the third layer 3 has a DSC melting point of 120 to 125°C and a density of 0.930 to 0.937g/cm 3 . Medical fluid bags can be made by using the multilayer film. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提供一种表现出优异的耐热性并且即使在高温灭菌后也能保持柔韧性和透明性的多层膜，并且当形成周边密封区域或切除不必要的部分时，其防止对切割器的粘合，并且提供使用该膜的药液袋，其制造方法以及医用流体袋的灭菌方法。解决方案：多层膜包括第一层（外层）1，其由例如包含55至85重量％的DSC熔点为120至200的线性聚乙烯（PE-L）的混合物制成 125℃，密度为0.930〜0.937g / cm 3，SP-熔点为160〜165℃，第二〜第五层的丙烯均聚物为15〜45重量％内层）2〜5，均由PE-L制成。第二层和第四层4具有120至125℃的DSC熔点和0.910至0.920g / cm 3的密度，而第三层3的DSC熔点为120至125℃ ℃，密度为0.930〜0.937g / cm 3。可以通过使用多层膜制造医用流体袋。版权所有（C）2010，JPO＆INPIT

10. 发明专利

JP2008132317A Dissolved oxygen-reducing liquid agent 有权
标题翻译：溶解氧化还原液体试剂
公开(公告)号：JP2008132317A
公开(公告)日：2008-06-12
申请号：JP2007276806
申请日：2007-10-24
申请人： Otsuka Pharmaceut Factory Inc , 株式会社大塚製薬工場
发明人： SUMIYOSHI NOBUAKI , TATEISHI ISAMU , MORI HITOSHI , MORIMOTO YASUSHI
IPC分类号： A61J1/10 , A61K9/08
摘要： PROBLEM TO BE SOLVED: To provide a dissolved oxygen reducing liquid agent for reducing the amount of dissolved oxygen, hardly deteriorated by oxidation and excellent in stability with the elapse of time. SOLUTION: The dissolved oxygen reducing liquid agent is housed in a chemical liquid container comprising a plastic of which the oxygen permeability under the condition of a temperature of 25°C and humidity RH of 60% within 12 hr after steam or hot water sterilization treatment is 200 cm 3 /m 2 *24h*atm or above and the oxygen permeability under the condition of a temperature of 25°C and humidity RH of 60% within 12 hr when the oxygen permeability is in a steady state, is 100 cm 3 /m 2 *24h*atm or below. After the container is hermetically sealed and subjected to steam or hot water sterilization treatment, the chemical liquid container is preserved under an environment equipped with a deoxidation means to adjust the concentration of dissolved oxygen of the liquid agent when the oxygen permeability of the plastic reaches the steady state becomes 2 ppm or below. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种溶解氧还原液剂，用于减少溶解氧的量，几乎不会因氧化而劣化，并且随着时间的推移稳定性优异。解决方案：将溶解的氧还原液剂容纳在包含塑料的药液容器中，该蒸汽或热水在12小时内在25℃的温度和湿度RH为60％的条件下具有氧气渗透性灭菌处理是在25℃的温度和湿度RH为60％的条件下的200cm 3 / SP 2 / SP 2 * / 24h * atm以上的氧气渗透性当氧气渗透率处于稳定状态时，为12小时，为100厘米3 /小时* 24小时*大气压以下。在将容器密封并进行蒸汽或热水杀菌处理之后，将化学液容器在具有脱氧装置的环境下保存，以在塑料的透氧性达到时调节液体剂的溶解氧浓度稳态变为2ppm以下。版权所有（C）2008，JPO＆INPIT

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