专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JPS6188888A Preparation of organic phosphoric acid ester derivative by enzymatic process 失效
标题翻译：通过酶法制备有机磷酸酯衍生物
公开(公告)号：JPS6188888A
公开(公告)日：1986-05-07
申请号：JP20993384
申请日：1984-10-08
申请人： Meito Sangyo Kk
发明人： KOKUSHO SUMITAKA , NAKAYAMA MINEO , TSUNODA AKIRA , KATO SHIGEAKI , MACHIDA HARUO , IWASAKI SHINJIRO
IPC分类号： C12P7/62 , C12P9/00 , C12P11/00 , C12P13/00 , C12P13/02 , C12P17/00 , C12P17/02 , C12P17/04 , C12P17/06 , C12P17/10 , C12P17/12 , C12P17/14 , C12P17/18
摘要： PURPOSE: To prepare a stable organic phosphoric acid ester derivative in high yield, at a low cost, by enzymatic method, by reacting a specific synthetic organic phosphoric acid ester with an alcoholic OH-containing compound acting as a receptor in the presence of a phospholipase DM.
CONSTITUTION: A synthetic organic phosphoric acid ester synthesizable easily is made to react with an alcoholic OH-containing compound acting as a recep tor, in the presence of a phospholipase DM. Organic phosphoric acid ester derivatives many of which are novel compounds and including known organic phosphoric acid ester derivatives which could, herebefore, be prepared only the disadvantageous synthetic method, can be prepared by this enzymatic process with little production of by-product, in high yield.
COPYRIGHT: (C)1986,JPO&Japio
摘要翻译：目的：为了通过酶法以低成本制备稳定的有机磷酸酯衍生物，通过使特定的合成有机磷酸酯与作为受体的含醇OH化合物在磷脂酶的存在下反应 DM。构成：在磷脂酶DM的存在下，容易合成的合成有机磷酸酯与作为受体的含醇的化合物反应。有机磷酸酯衍生物，其中许多是新型化合物，并且包括已知的有机磷酸酯衍生物，其可以仅制备不利的合成方法，可以通过这种酶法以少量的副产物高产率制备。

2. 发明专利

JPS5851889A HIGH-ACTIVITY LIPASE-PRODUCING BACTERIUM AND PRODUCTION OF LIPASE 失效
公开(公告)号：JPS5851889A
公开(公告)日：1983-03-26
申请号：JP14963481
申请日：1981-09-24
申请人： MEITO SANGYO KK
发明人： MACHIDA HARUO , KOKUSHIYOU SUMITAKA , AZUMA SUSUMU , NAKAYAMA MINEO , SHIMIZU NORIO , TSUNODA TERU
IPC分类号： C12N9/20 , C12N1/16 , C12R1/72
摘要： PURPOSE:A mutant that is derived from Candida cylindracea and does not assimilate xylose is used to produce high-activity and high-unit lipase. CONSTITUTION:Candida cylindracea (ATCC14830) is cultured and a mutagen such as N-methyl-N'-nitrosoguanidine, ultraviolet rays or X-rays are used to obtain a mutant that does not assimilate xylose and produces high-unit lipase (FERM 6137, 6134, 6135 or 6136). The mutant is cultured in a liquid medium containing carbon source, nitrogen source and minerals under aeration and lipase is collected from the culure mixture and purified.

3. 发明专利

JPS5344691A PREPARATION OF LLMENTHOL FROM MENTHOL RACEMATE 失效
公开(公告)号：JPS5344691A
公开(公告)日：1978-04-21
申请号：JP11793176
申请日：1976-10-02
申请人： TAKASAGO PERFUMERY CO LTD , MEITO SANGYO KK
发明人： NAKAYAMA MINEO , YAMAGUCHI YUUZOU , MACHIDA HARUO , IWASAKI SHINJIROU , KOMATSU AKIRA , SHINODA AKIRA
IPC分类号： C12P7/22 , C07C35/12 , C12P7/02 , C12P41/00 , C12R1/07 , C12R1/08 , C12R1/39 , C12R1/645 , C12R1/66 , C12R1/685 , C12R1/72 , C12R1/785 , C12R1/845 , C12R1/85 , C12R1/88
摘要： PURPOSE:To prepare highly pure l-menthol by acting esterase to a mixture of menthol racemate and a higher fatty acid, followed by the hydrolysis of the resulting ester containing l-menthylester as a main component.

4. 发明专利

JPH0656856A PHOSPHOLIPID DERIVATIVE 失效
公开(公告)号：JPH0656856A
公开(公告)日：1994-03-01
申请号：JP11388593
申请日：1993-04-16
申请人： MEITO SANGYO KK
发明人： KOKUSHO SUMITAKA , NAKAYAMA MINEO , TSUNODA AKIRA , KATO SHIGEAKI , MACHIDA HARUO , IWASAKI SHINJIRO
IPC分类号： A61K47/24 , B01F17/14 , B01J13/02 , C07F9/10 , C07F9/655 , C12N9/16 , C12P17/04 , C12P17/06 , C12R1/01 , C12R1/03
摘要： PURPOSE:To provide the phospholipid derivative useful as a base material for formation of a liposome, an emulsifier, a bioactive substance and its carrier, etc. CONSTITUTION:A compound of formula I [A is formula II (R1 and R2 are each a 7 to 21C fatty acid residue), etc.; A' is OH or O; C is formula III, etc.]. In addition, the compound of formula I can be obtained by reacting a phospholipid of formula IV [B is (CH2)2N (CH3)3, (CH2)2NH, etc.] with ascorbic acid or kojic acid in the presence of phospholipase D exhibiting a catalytic effect on a transfer reaction between a phospholipid and a heterocyclic alcohol.

5. 发明专利

JPS6188886A Preparation of phospholipid long-chain alcohol derivative by enzymatic process 失效
标题翻译：通过酶法制备磷脂长链醇衍生物
公开(公告)号：JPS6188886A
公开(公告)日：1986-05-07
申请号：JP20993184
申请日：1984-10-08
申请人： Meito Sangyo Kk
发明人： KOKUSHO SUMITAKA , NAKAYAMA MINEO , TSUNODA AKIRA , KATO SHIGEAKI , MACHIDA HARUO , IWASAKI SHINJIRO
IPC分类号： C07F9/10 , A61K9/127 , C12P7/02 , C12P7/40 , C12P7/62 , C12P9/00 , C12P13/00 , C12P13/02
CPC分类号： A61K9/1271
摘要： PURPOSE: To obtain the titled phospholipid alcohol derivative such as phospholipid polyethylene glycol derivative, in high yield, by reacting a phospholipid with an alcohol in the presence of a phospholipase DM at specific temperature and pH.
CONSTITUTION: A phospholipid of formula I {A is group of formula II or formu la III [R
1 and R
2 or -O-COR
11 or -O-R
12 (R
11 and R
12 are 1W21C aliphatic hydro carbon residue)]; A' is oxide anion or OH; B is -(CH
2 )
2 N
+ (CH
3 )
3 , -(CH
2 )
2 NH
2 , etc.} is made to react with an alcohol compound at 60W70°C and about 7pH in the presence of a phospholipase DM. The alcoholic compound is a primary alcohol having ≥27C aliphatic or aromatic hydrocarbon residue (which may have substituent group such as halogen or an ether bond, etc. in the molecule) or a secondary alcohol compound having ≥11C alkyl residue which may be substituted with halogen, amino, etc.
COPYRIGHT: (C)1986,JPO&Japio
摘要翻译：目的：通过在磷脂酶DM的存在下，在特定温度和pH下使磷脂与醇反应，以高产率获得标题磷脂醇衍生物如磷脂聚乙二醇衍生物。构型：式I的磷脂（A是式II或式IIIIII的基团[R1和R2或-O-COR11或-O-R12（R11和R12是1-21C脂肪族氢碳残基）]; A'是氧化物阴离子或OH; 在磷脂酶DM存在下，B为 - （CH 2）2 N +（CH 3）3， - （CH 2）2 NH 2等）与醇化合物在60-70℃和约7pH反应。醇化合物是具有> = 27C脂族或芳族烃残基（其分子中可具有取代基如卤素或醚键等）的伯醇或具有> = 11C烷基残基的仲醇化合物，其可以是被卤素，氨基等取代

6. 发明专利

JPH0588114B2 失效
公开(公告)号：JPH0588114B2
公开(公告)日：1993-12-21
申请号：JP20993084
申请日：1984-10-08
申请人： MEITO SANGYO KK
发明人： KOKUSHO SUMITAKA , NAKAYAMA MINEO , TSUNODA AKIRA , KATO SHIGEAKI , MACHIDA HARUO , IWASAKI SHINJIRO
IPC分类号： C12P17/00 , C12N9/16 , C12P17/02 , C12P17/04 , C12P17/06 , C12P17/10 , C12P17/12 , C12P17/14 , C12P17/18 , C12P19/02 , C12P19/30 , C12P19/32 , C12R1/01 , C12R1/03

7. 发明专利

JPS61149098A PRODUCTION OF FATTY ACID FROM ALKALI OIL CAKE 失效
公开(公告)号：JPS61149098A
公开(公告)日：1986-07-07
申请号：JP27207784
申请日：1984-12-25
申请人： MEITO SANGYO KK
发明人： KOKUSHO SUMITAKA , NAKAYAMA MINEO , IWASAKI SHINJIRO
IPC分类号： C11B13/02 , C11C1/02 , C12P7/64
摘要： PURPOSE:To obtain high-quality fatty acids effectively for energy saving and pollution policy, by treating alkali oil cake with lipase to give decomposed oil cake, adding an acid to the cake to liberate fatty acids and heat-treating them with an emulsion breaking agent. CONSTITUTION:1pt.vol. alkali oil cake of fat and oil purification process of rice bran oil, beaf tallow, etc., is blended with =95% of the mixture is decomposed at 30-50 deg.C for

8. 发明专利

JPH0571236B2 失效
公开(公告)号：JPH0571236B2
公开(公告)日：1993-10-06
申请号：JP20993384
申请日：1984-10-08
申请人： MEITO SANGYO KK
发明人： KOKUSHO SUMITAKA , NAKAYAMA MINEO , TSUNODA AKIRA , KATO SHIGEAKI , MACHIDA HARUO , IWASAKI SHINJIRO
IPC分类号： C12P7/62 , C12P9/00 , C12P11/00 , C12P13/00 , C12P13/02 , C12P17/00 , C12P17/02 , C12P17/04 , C12P17/06 , C12P17/10 , C12P17/12 , C12P17/14 , C12P17/18

9. 发明专利

JPS6188890A Preparation of phospholipid heterocyclic compound derivative by enzymatic process 失效
标题翻译：通过酶学方法制备衍生的磷脂杂环化合物
公开(公告)号：JPS6188890A
公开(公告)日：1986-05-07
申请号：JP20992984
申请日：1984-10-08
申请人： Meito Sangyo Kk
发明人： KOKUSHO SUMITAKA , NAKAYAMA MINEO , TSUNODA AKIRA , KATO SHIGEAKI , MACHIDA HARUO , IWASAKI SHINJIRO
IPC分类号： C12P17/00 , C12N9/16 , C12P17/02 , C12P17/04 , C12P17/06 , C12P17/10 , C12P17/12 , C12P17/14 , C12P17/18 , C12P19/02 , C12P19/30 , C12P19/32 , C12R1/01 , C12R1/03
CPC分类号： Y02P20/52
摘要： PURPOSE: To produce the titled novel derivative which could not hitherto be produced, by reacting a specific phospholipid with a heterocyclic compound having a specific alcoholic OH group in the presence of a phospholipase DM.
CONSTITUTION: A phospholipid of formula I {A is group of formula II or formu la III [R
1 and R
2 are -O-COR
11 or -O-R
12 (R
11 is 7W21C aliphatic hydrocarbongroup); R
12 is 1W21C aliphatic hydrocarbon group)]; A' is oxide anion or OH; B is -(CH
2 )
2 N
+ (CH
3 )
3 ), -(CH
2 )
2 NH
2 , etc.}is made to react with a heterocyclic compound having an aloholic OH group in the presence of a phospholipase DM. The above OH group is (i) a reside of a heterocyclic primary alcohol compound having chain side group bonded to a primary alcoholic OH and having a heterocyclic group such as furan ring, (ii) a heterocyclic secondary alcohol compound residue having a heterocyclic group such as piperidine ring, or (iii) a (deoxy)pentose residue having pyridine ring, etc. as a substituent group.
COPYRIGHT: (C)1986,JPO&Japio
摘要翻译：目的：在磷脂酶DM的存在下，通过使具体的磷脂与具有特定的醇OH基团的杂环化合物反应，生产迄今无法生产的标题新型衍生物。构型：式I的磷脂（A是式II或式IIIIII的基团[R1和R2是-O-COR11或-O-R12（R11是7-21C脂族烃族基））。 R12为1-21C脂族烃基）]; A'是氧化物阴离子或OH; 在磷脂酶DM的存在下，B是 - （CH 2）2 N +（CH 3）3）， - （CH 2）2 NH 2等与具有天然OH基团的杂环化合物反应。上述OH基是（i）具有键侧基的杂环伯醇化合物与主要醇OH键合并具有杂环基的呋喃环，（ii）具有杂环基的杂环仲醇化合物残基如作为哌啶环，或（iii）具有吡啶环的（脱氧）戊糖残基等作为取代基。

10. 发明专利

JPH0588113B2 失效
公开(公告)号：JPH0588113B2
公开(公告)日：1993-12-21
申请号：JP20992984
申请日：1984-10-08
申请人： MEITO SANGYO KK
发明人： KOKUSHO SUMITAKA , NAKAYAMA MINEO , TSUNODA AKIRA , KATO SHIGEAKI , MACHIDA HARUO , IWASAKI SHINJIRO
IPC分类号： C12P17/00 , C12N9/16 , C12P17/02 , C12P17/04 , C12P17/06 , C12P17/10 , C12P17/12 , C12P17/14 , C12P17/18 , C12P19/02 , C12P19/30 , C12P19/32 , C12R1/01 , C12R1/03

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式