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1. 发明专利

JP2003289892A Process for producing culture of antrodia camphorata and product obtained thereby 有权
标题翻译：生产ANTRODIA CAMPHORATA文化及其产品的方法
公开(公告)号：JP2003289892A
公开(公告)日：2003-10-14
申请号：JP2002268194
申请日：2002-09-13
申请人： Korea Food Developing Res Inst , 食品工業発展研究所
发明人： WU MEI-CHIAO , HUANG REN-CHANG , LIN SHIE-JEA , WANG BOR-CHEH
IPC分类号： C12P1/02 , A61K36/06 , A61P35/00 , C12N1/14 , C12R1/645 , A61K35/70
摘要： PROBLEM TO BE SOLVED: To establish culture conditions suitable for the large scale production of a pharmacologically active filtrate from an Antrodia camphorata culture by optimizing an agitation speed and/or pH value during the culture. SOLUTION: A process for producing the Antrodia camphorata culture having an pharmacological activity, comprises: (a) inoculating a mycelial inoculum of an isolate of Antrodia camphorata into a medium suitable for the growth of the isolate to result in a first culture; (b) subjecting the first culture cultivated in the step (a) to a first stage of agitation which is set at a first predetermined rate and for a first period of time to allow further growth of the inoculated isolate, so as to obtain a second culture proliferation containing the mycelium; and (c) subjecting the second culture obtained in the step (b) to a second stage of agitation which is set at a second predetermined rate different from the first predetermined rate, so as to subject the isolate under physiological stress. COPYRIGHT: (C)2004,JPO
摘要翻译：要解决的问题：通过优化培养过程中的搅拌速度和/或pH值，建立适合于从樟芝（Antrodia camphorata）培养物大规模生产药理活性滤液的培养条件。解决方案：用于生产具有药理活性的樟芝的培养物的方法包括：（a）将樟脑的分离株的菌丝体接种物接种到适于分离物生长的培养基中以产生第一次培养; （b）将在步骤（a）中培养的第一培养物进行第一阶段的搅拌，所述第一阶段设定为第一预定速率并持续第一时间段以允许接种的分离物进一步生长，以获得第二阶段含有菌丝体的培养物增殖; 和（c）将步骤（b）中获得的第二培养物进行第二阶段的搅拌，所述第二阶段设定为与第一预定速率不同的第二预定速率，以便在生理压力下使分离物受到影响。版权所有（C）2004，JPO

2. 发明专利

JP2006288405A Process for producing a culture of antrodia camphorata and product obtained thereby 有权
标题翻译：生产阿托品的文化和产品获得的方法
公开(公告)号：JP2006288405A
公开(公告)日：2006-10-26
申请号：JP2006195298
申请日：2006-07-18
申请人： Korea Food Developing Res Inst , 食品工業発展研究所
发明人： WU MEI-CHIAO , HUANG REN-CHANG , LIN SHIE-JEA , WANG BOR-CHEH
IPC分类号： C12P1/02 , A61K36/06 , A61P35/00 , C12N1/14 , C12R1/645
摘要： PROBLEM TO BE SOLVED: To develop a cost-effective process on an artificial culturing of Antrodiac camphorata. SOLUTION: This process for producing the Antrodiac camphorata culture having pharmacologically activity comprises (a) inoculating a mycelium inoculum of an Antrodiac camphorata isolate into a liquid culture medium suitable for the proliferation of the isolate to obtain the first culture product, (b) supplying the first culture from the process (a) to the first step stirring treatment set to the first period and the first prescribed rate enabling the furthermore culturing of the inoculated isolate to obtain the second culture having the proliferated mycelia, and (c) supplying the second culture obtained from the process (b) to the second step stirring treatment set to the larger second prescribed rate than that of the first prescribed rate to subject the isolate to a treatment under a physiological stress. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：开发人造培养茜草花的成本效益过程。解决方案：该制备具有药理学活性的茜素类脯氨酸培养物的方法包括：（a）将抗茜素樟脑分离物的菌丝体接种物接种到适于分离物增殖的液体培养基中，得到第一培养产物（b ）将第一培养物从步骤（a）提供到第一阶段的第一步骤搅拌处理和第一规定速率，从而进一步培养接种的分离物以获得具有增殖菌丝体的第二培养物，和（c）将从步骤（b）至第二步骤搅拌处理得到的第二培养物设定为比第一规定速率更大的第二规定速率，以使分离物在生理胁迫下进行处理。版权所有（C）2007，JPO＆INPIT

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