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1. 发明专利

JP2012250994A Detergent composition 审中-公开
标题翻译：洗涤剂组合物
公开(公告)号：JP2012250994A
公开(公告)日：2012-12-20
申请号：JP2012200568
申请日：2012-09-12
申请人： Kao Corp , 花王株式会社
发明人： SOGA HAJIME , MATSUI TOSHIHIKO , SAKAI ATSUSHI
IPC分类号： A61K8/34 , A61K8/03 , A61K8/19 , A61K8/35 , A61K8/37 , A61K8/42 , A61K8/44 , A61K8/46 , A61K8/49 , A61K8/60 , A61K8/891 , A61K8/92 , A61Q5/02 , A61Q19/10 , C11D1/14 , C11D1/29 , C11D1/52 , C11D1/90 , C11D3/20 , C11D3/37 , C11D3/50 , C11D7/20
摘要： PROBLEM TO BE SOLVED: To provide a detergent composition having excellent stability of a crystalline refrigerant such as menthol etc., at low temperature, excellent segregational stability of optionally added highly polymerized silicone etc., in preservation at high temperature, and having beautiful pearl luster.SOLUTION: The detergent composition contains following ingredients (a)-(d), and does not include a clay mineral with swelling power of 55 mL/2g or more and a clay mineral with swelling power of less than 55 mL/2g. The (a) is 2-40 mass% of at least one surfactant selected from the group composed of a polyoxyethylene alkyl ether sulfate, an alkyl sulfate, a fatty acid alkanolamide and a fatty acid amide propyl betaine, the (b) is 0.1-3 mass% of ethanol, (c) is 0.05-2 mass% of at least one refrigerant selected from the group composed of menthol, menthone, camphor, borneol, cineole menthone, methyl salicylate, menthyl malonate, glycosyl monomenthyl-O-acetate, 3-1-menthoxypropane-1,2-diol, 1-menthyl-3-hydroxybutyrate, spearmint oil, peppermint oil, mint oil, and eucalyptus oil, (d) is 0.1-10 mass% of at least one pearling agent selected from the group composed of an ethylene glycol monofatty acid ester, an ethylene glycol difatty acid ester, an ethylene glycol monoalkyl ether, and an ethylene glycol dialkyl ether.
摘要翻译：要解决的问题：提供一种在低温下，结晶制冷剂如薄荷醇等具有优异稳定性的洗涤剂组合物，任选添加的高分子聚合的硅氧烷等的优异的分散稳定性，在高温保存时具有优异的分离稳定性，并具有美丽的珍珠光泽。洗涤剂组合物含有以下成分（a） - （d），不包括溶胀力为55mL / 2g以上的粘土矿物和具有小于55mL / 2g的溶胀力的粘土矿物。（a）为2-40质量％的选自由聚氧乙烯烷基醚硫酸盐，烷基硫酸盐，脂肪酸烷醇酰胺和脂肪酸酰胺丙基甜菜碱组成的组中的至少一种表面活性剂，（b）为0.1〜 3质量％的乙醇，（c）为0.05〜2质量％的选自由薄荷醇，薄荷酮，樟脑，冰片，桉树脑薄荷酮，水杨酸甲酯，丙烯酸薄荷酯，糖基单薄荷醇O-乙酸酯， 3-1-薄荷氧基丙-1,2-二醇，1-薄荷基-3-羟基丁酸酯，薄荷油，薄荷油，薄荷油和桉树油，（d）为0.1-10质量％的至少一种选自由乙二醇单脂酸酯，乙二醇二癸酸酯，乙二醇单烷基醚和乙二醇二烷基醚组成的组。版权所有（C）2013，JPO＆INPIT

2. 发明专利

JP2004267095A Bedsore model animal 审中-公开
标题翻译： BEDSORE模型动物
公开(公告)号：JP2004267095A
公开(公告)日：2004-09-30
申请号：JP2003062033
申请日：2003-03-07
申请人： Kao Corp , 花王株式会社
发明人： SOGA HAJIME , OUCHI ATSUSHI , MORIWAKI SHIGERU
IPC分类号： A01K67/027
摘要： PROBLEM TO BE SOLVED: To easily provide an experimental model animal capable of reproducing a bedsore-like skin necrotic condition.
SOLUTION: A method for creating a bedsore model animal comprises picking up the skin of an experimental mammal, nipping the skin in between two hard and flat plates, fixing both sides thereof with clips and then carrying out a press treatment under a pressure of 0.015-15 MPa for 3-24 h.
COPYRIGHT: (C)2004,JPO&NCIPI
摘要翻译：要解决的问题：为了容易地提供能够再现褥疮样皮肤坏死状况的实验模型动物。解决方案：用于产生褥疮模型动物的方法包括拾取实验哺乳动物的皮肤，将皮肤夹在两个硬和平板之间，用夹子固定两侧，然后在压力下进行压力处理 0.015-15MPa 3-24小时。版权所有（C）2004，JPO＆NCIPI

3. 发明专利

JP2012017298A Method of using hair cosmetic, and the hair cosmetic 审中-公开
标题翻译：使用头发化妆品的方法和头发化妆品
公开(公告)号：JP2012017298A
公开(公告)日：2012-01-26
申请号：JP2010156197
申请日：2010-07-08
申请人： Kao Corp , 花王株式会社
发明人： SOGA HAJIME
IPC分类号： A61K8/92 , A61Q5/12
摘要： PROBLEM TO BE SOLVED: To provide a method of using a hair cosmetic capable of giving a voluminous feel by making hair stand up at a stroke.SOLUTION: The method of using the hair cosmetic consists of (i) a process that applies the hair cosmetic on a scalp, and (ii) a process that contacts the hair cosmetic with the hair while spreading the cosmetic zigzag over the scalp.
摘要翻译：要解决的问题：提供一种通过使头发中立起来能够产生大量感觉的头发化妆品的使用方法。使用毛发化妆品的方法包括：（i）将头发化妆品应用于头皮上的方法，和（ii）将头发化妆品与头发接触的过程同时将化妆品之字形涂抹在头皮上。版权所有（C）2012，JPO＆INPIT

4. 发明专利

JP2011131093A Device to improve flesh color around eye 有权
标题翻译：改善眼睛周围颜色的装置
公开(公告)号：JP2011131093A
公开(公告)日：2011-07-07
申请号：JP2011083037
申请日：2011-04-04
申请人： Kao Corp , 花王株式会社
发明人： TONE HIROSHI , AIZAWA HIROYUKI , ODA HIDESHI , FUJINAMI SUSUMU , SOGA HAJIME , FUKUDA YUKO
IPC分类号： A61F7/00 , A61H33/12 , A61H35/00
摘要： PROBLEM TO BE SOLVED: To provide a device which can reduce shade, somberness, swelling or the like generated around an eye.
SOLUTION: The device 1 to improve the flesh color around the eye applies the heat accompanied by steam which is generated by utilizing the oxidation reaction of an oxidizable metal to the periphery of the eye. The device 1 has a steam generating section 6 having an area of 1,500-4,000 mm
2 which can transfer the heat accompanied by the steam. The steam generating section 6 has the width from the medial angle of the eye to the outside of 20 mm from the lateral angle of the eye of the user, and has a shape to cover the upper eyelid and the lower eyelid of the closed eye. Also, it has a steam generating capacity to keep the average skin temperature of a contact section at 38°C or higher and lower than 45°C for 8-15 minutes in the condition that the device 1 comes in contact with the periphery of the eye of the user.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供一种可以减轻眼睛周围产生的阴影，阴影，肿胀等的装置。解决方案：用于改善眼睛周围的肉色的装置1将通过利用可氧化金属的氧化反应产生的蒸汽伴随的热量施加到眼睛周围。装置1具有蒸汽发生部分6，该蒸汽发生部分6具有1,500-4,000mm 2 的面积，其可以传递伴随蒸汽的热量。蒸汽发生部分6具有从使用者的眼睛的横向角度开始的从眼睛的中间角到外侧的宽度20mm的宽度，并且具有覆盖闭眼的上眼睑和下眼睑的形状。另外，具有将发生接触部的平均皮肤温度保持在38℃以上且低于45℃8〜15分钟的蒸汽发生能力，在装置1与眼睛的用户。版权所有（C）2011，JPO＆INPIT

5. 发明专利

JP2009035520A Detergent composition 审中-公开
标题翻译：洗涤剂组合物
公开(公告)号：JP2009035520A
公开(公告)日：2009-02-19
申请号：JP2007202722
申请日：2007-08-03
申请人： Kao Corp , 花王株式会社
发明人： SOGA HAJIME , MATSUI TOSHIHIKO , SAKAI ATSUSHI
IPC分类号： A61K8/33 , A61K8/34 , A61K8/35 , A61K8/37 , A61K8/42 , A61K8/44 , A61K8/46 , A61K8/60 , A61K8/73 , A61K8/891 , A61K8/92 , A61K8/97 , A61Q5/02 , C11D1/02 , C11D1/66 , C11D1/88 , C11D3/20 , C11D3/37 , C11D3/50
摘要： PROBLEM TO BE SOLVED: To obtain a detergent composition that has excellent stability of a crystalline refreshment such as menthol etc., at a low temperature, excellent separation stability of highly polymerized silicone, etc., added if necessary, even in preservation at a high temperature and a beautiful pearl gloss.
SOLUTION: The detergent composition comprises (a) 2-40 mass% of an anionic, nonionic or amphoteric surfactant, (b) 0.1-3 mass% of ethanol, (c) a refreshment selected from menthol etc., and (d) 0.1-10 mass% of a pearlizing agent selected from an ethylene glycol difatty acid ester etc.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：待解决的问题：为了获得在低温下具有优异的结晶更新稳定性的洗涤剂组合物，如果需要，加入高分子聚硅氧烷等的优异的分离稳定性，即使在保存在高温和美丽的珍珠光泽。洗涤剂组合物包含（a）2-40质量％的阴离子，非离子或两性表面活性剂，（b）0.1-3质量％的乙醇，（c）选自薄荷醇等的茶点和（ d）0.1-10质量％的选自乙二醇二脂肪酸酯等的珠光剂。（C）2009，JPO＆INPIT

6. 发明专利

JP2004271319A Method for preventing decubitus or screening therapeutic product 审中-公开
公开(公告)号：JP2004271319A
公开(公告)日：2004-09-30
申请号：JP2003061744
申请日：2003-03-07
申请人： Kao Corp , 花王株式会社
发明人： SOGA HAJIME , OUCHI ATSUSHI , MORIWAKI SHIGERU
IPC分类号： G01N33/50 , A61K31/155 , A61K31/198 , A61K31/355 , A61K31/375 , A61P17/02 , A61P43/00 , G01N33/15
摘要： PROBLEM TO BE SOLVED: To establish and provide a new evaluation system for preventing decubitus and screening a therapeutic product outside a living body.
SOLUTION: A method for preventing the decubitus or screening the therapeutic product applies a weight load treatment for developing dermonecrotic like the decubitus to a skin of an experimental mammal, collects a skin structure from a treated part just after a release of the treatment, incubates the skin structure in an environment of a tested compound and measures a change of respiration activity of the skin structure from 0 to 3 days after incubation.
COPYRIGHT: (C)2004,JPO&NCIPI

7. 发明专利

JP2006036673A Blood vessel-strengthening agent 审中-公开
标题翻译：血管增强剂
公开(公告)号：JP2006036673A
公开(公告)日：2006-02-09
申请号：JP2004217647
申请日：2004-07-26
申请人： Kao Corp , 花王株式会社
发明人： SOGA HAJIME , YOSHIZUKA NAONOBU , FUKUDA YUKO , MORI SHINOBU
IPC分类号： A61K36/00 , A61K36/02 , A61K36/18 , A61K36/28 , A61K36/42 , A61K36/53 , A61K36/75 , A61K36/896 , A61K36/899 , A61P7/04 , A61P9/00 , A61P9/14 , A61P17/00 , A61P17/16 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide a blood vessel-strengthening agent having excellent blood vessel-strengthening action and useful as a medicine or a cosmetic. SOLUTION: The blood vessel-strengthening agent comprises a plant selected from rosemary, sage, Geranium thunbergii Siebold et Zuccarini (Geraniaceae), Coix lacryma-jobi L. var., Equisetum arvense L, Citrus aurantium Linne or Citrus aurantium Linne var. daidai Makino, Fucus Vesiculosis, Arctium lappa Linne (Compositae), Houttuynia cordata Thunberg (Saururaceae), Zanthoxylum piperitum De Candolla or a plant of the same genus, Ophiopogon japonica or a plant of the same genus, Ginkgo biloba Linne (Ginkgoaceae), Zizyphus jujuba MILL. var. inermis (BUNGE) REHD. and Luffa cylindrica M. Reomen (Cucurbitaceae) or Luffa cylindrica (Cucurbitaceae), or its extract as an active ingredient. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供具有优异的血管强化作用的血管强化剂，并且可用作药物或化妆品。解决方案：血管强化剂包括选自迷迭香，鼠尾草，天竺葵（Siebold）和茜草（Geraniaceae），ix藜（Coix lacryma-jobi L. var。），白，，（Equisetum arvense L），枸杞（Citrus aurantium Linne）。 d ai Mak，，hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus hus 朱朱山变种。真皮（BUNGE）REHD。和Luffa cylindrica M. Reomen（葫芦科）或Luffa cylindrica（葫芦科），或其提取物作为活性成分。版权所有（C）2006，JPO＆NCIPI

8. 发明专利

JP2006034157A Method for screening capillary stabilizer 审中-公开
标题翻译：筛选毛细管稳定剂的方法
公开(公告)号：JP2006034157A
公开(公告)日：2006-02-09
申请号：JP2004217648
申请日：2004-07-26
申请人： Kao Corp , 花王株式会社
发明人： SOGA HAJIME , MORI SHINOBU , FUKUDA YUKO , YOSHIZUKA NAONOBU
IPC分类号： C12Q1/02 , G01N33/15
摘要： PROBLEM TO BE SOLVED: To provide a method for readily and precisely screening a capillary stabilizer or the like in vitro.
SOLUTION: The method for screening a shrinkage inhibitor of a vascular endothelial cell or the capillary stabilizer comprises culturing a collagen gel seeded with the vascular endothelial cell, with a tested sample for a prescribed time, and measuring a gel area of the collagen gel to judge the gel shrinkage-inhibiting effects of the test sample.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种容易且精确地筛选毛细管稳定剂等的体外方法。解决方案：用于筛选血管内皮细胞或毛细管稳定剂的收缩抑制剂的方法包括用测试的样品培养接种血管内皮细胞的胶原凝胶一段规定的时间，并测量胶原蛋白的凝胶面积凝胶来测定试样的凝胶收缩抑制效果。版权所有（C）2006，JPO＆NCIPI

9. 发明专利

JP2006340928A DEVICE TO IMPROVE FLESH COLOR AROUND EYE 审中-公开
公开(公告)号：JP2006340928A
公开(公告)日：2006-12-21
申请号：JP2005170053
申请日：2005-06-09
申请人： KAO CORP
发明人： TONE HIROSHI , AIZAWA HIROYUKI , ODA HIDESHI , FUJINAMI SUSUMU , SOGA HAJIME , FUKUDA YUKO
IPC分类号： A61F7/00 , A61F7/08 , A61F9/04 , A61H33/12
摘要： PROBLEM TO BE SOLVED: To provide a device which can reduce a shade, the dimness, a swelling or the like generated around an eye. SOLUTION: The device 1 to improve the flesh color around the eye applies the heat accompanied by steam which is generated by utilizing the oxidation reaction of an oxidizable metal to the periphery of the eye. The device 1 has a steam generating section 6 having an area of 1,500-4,000 mm 2 which can transfer the heat accompanied by the steam. The steam generating section 6 has the width from the medial angle of the eye to the outside of 20 mm from the lateral angle of the eye and has a shape to cover the upper eyelid and the lower eyelid of the closed eye. Also, it has a steam generating capacity to keep the average skin temperature of a contacting section at 38°C or higher and lower than 45°C for 8-15 minutes in the condition that the device 1 comes in contact with the periphery of the eye of the user. COPYRIGHT: (C)2007,JPO&INPIT

10. 发明专利

JP2001031550A VERATRYL ETHER DERIVATIVE 失效
公开(公告)号：JP2001031550A
公开(公告)日：2001-02-06
申请号：JP20039699
申请日：1999-07-14
申请人： KAO CORP
发明人： OBA TAKASHI , SOGA HAJIME , YAMAMURO AKIRA , KITAHARA KO , KAIZU KAZUHIRO
IPC分类号： A61K8/00 , A61K8/30 , A61K8/39 , A61K31/00 , A61K31/09 , A61P9/00 , A61Q19/00 , A61K7/48 , A61K7/00
摘要： PROBLEM TO BE SOLVED: To obtain a blood circulation-promoting agent which exhibits a blood circulation-promoting action, gives a persistent warm-sensitive effect to skin, scarcely gives an unpleasant skin-irritating touch to a human body, and is useful for medicines or cosmetics, by including a specific veratryl ether derivative. SOLUTION: This blood circulation-promoting agent contains a veratryl ether derivative of the formula [R1 is a 1 to 18C alkyl or a 7 to 24C aralkyl; (m) is 0 to 2] as an active ingredient. The content of the compound of the formula is preferably 0.001 to 10 wt.%. One or more compounds among the compounds of the formula may be used for the blood circulation-promoting agent. One or more other compounds giving warm-sensitive touches or one or more plant extracts having blood circulation-promoting effects, such as the powder of red pepper, may together be used to further improve the heat-sensitive effect without strengthening a skin-irritating touch. The compound of the formula can be obtained by reacting veratryl alcohol with an alcohol in the presence of a strong acid as a dehydrating agent.

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