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1. 发明专利

JPS644803B2 失效
公开(公告)号：JPS644803B2
公开(公告)日：1989-01-26
申请号：JP18633580
申请日：1980-12-30
申请人： KURARAY CO
发明人： AKASU HIROYUKI , MIGAKI TAKAO , KAWAI SHUJI
IPC分类号： B01D63/02

2. 发明专利

JPH0614966B2 失效
公开(公告)号：JPH0614966B2
公开(公告)日：1994-03-02
申请号：JP26375388
申请日：1988-10-18
申请人： KURARAY CO
发明人： MIMURA RISHICHI , AKASU HIROYUKI , MIGAKI TAKAO , YAMAUCHI TAKASHI , KUSACHI MICHIO
IPC分类号： B01D63/02 , A61M1/18

3. 发明专利

JPH02109572A HOLLOW YARN TYPE FLUID TREATING DEVICE 失效
公开(公告)号：JPH02109572A
公开(公告)日：1990-04-23
申请号：JP26375388
申请日：1988-10-18
申请人： KURARAY CO
发明人： MIMURA RISHICHI , AKASU HIROYUKI , MIGAKI TAKAO , YAMAUCHI TAKASHI , KUSACHI MICHIO
IPC分类号： B01D63/02 , A61M1/18
摘要： PURPOSE:To prevent channeling and to decrease a pressure drop by segmenting the inside of a housing to a blood inlet or outlet chamber and a gas exchange chamber by a partition wall and forming blood flow passages regulated by warp and hollow yarn between the hollow yarn sheets crimped by two sheets of perforated plates in the exchange chamber. CONSTITUTION:The inside of the square cylindrical housing 1 is segmented to the blood inlet chamber A and the gas exchange chamber B by the partition wall 2. The laminate of the hollow yarn sheets formed like a screen is housed between two sheets of the perforated plates 3 and 3' of the gas exchange chamber B. Both ends of the plates 3, 3' and the hollow yarn 4 are liquidtightly supported by the upper and lower resin partition walls 5, 5' closing both ends of the housing 1. A blood inlet 10 communicating with the blood inlet chamber A and a blood outlet 11 communicating with the gas exchange chamber B are provided to the side wall 5. The blood chamber A and the exchange chamber B are communicated by an aperture 6 in the lower part of the partition wall 2. The top and bottom ends of the housing 1 respectively have a gas inlet 12 and gas outlet 3 communicating with the inside space of the hollow yarn 4. The channeling is prevented in this way and the gas exchange capacity per unit area is improved.

4. 发明专利

JPH0299067A HOLLOW FIBER TYPE FLUID TREATMENT APPARATUS 失效
公开(公告)号：JPH0299067A
公开(公告)日：1990-04-11
申请号：JP25465188
申请日：1988-10-07
申请人： KURARAY CO
发明人： MIMURA RISHICHI , AKASU HIROYUKI , MIGAKI TAKAO , YAMAUCHI TAKASHI , KUSACHI MICHIO
IPC分类号： A61M1/14 , A61M1/18
摘要： PURPOSE:To prevent channeling and to reduce pressure loss by winding a hollow fiber sheet formed into a reed screen shape around porous inner cylinder and receiving the same in a porous outer cylinder. CONSTITUTION:The blood introduced into a porous inner cylinder 3 from a blood inlet 11 flows in a gas exchange chamber from the openings bored in the porous inner cylinder 3 to flow in the outer peripheral direction thereof and flows out from the blood outlet 12 provided to the upper side wall of a cylindrical housing 1. The gas introduced into hollow fibers from a gas inlet 10 flows toward the lower part of the cylindrical housing 1. In this external perfusion type artificial lung, a reed screen like hollow fiber sheet is wound around the porous inner cylinder 3 and received in an outer cylinder 4. In this case, one hollow fiber sheet formed into a reed screen shape from hollow yarns arranged in parallel or bundles 41 each composed of a plurality of hollow fibers by longitudinal yarns 40 may be continuously wound around the porous inner cylinder 3 or two reed screen like hollow fiber sheets may be wound around the porous inner cylinder 3 in such a state that the hollow fibers of the upper and lower sheets are superposed so as to have an angle alternately.

5. 发明专利

JPS648977A HOLLOW YARN TYPE OXYGENATOR 失效
公开(公告)号：JPS648977A
公开(公告)日：1989-01-12
申请号：JP16614687
申请日：1987-07-01
申请人： KURARAY CO
发明人： YAMAUCHI TAKASHI , KUSACHI MICHIO , MIMURA RISHICHI , MIGAKI TAKAO , AKASU HIROYUKI
IPC分类号： A61M1/18 , A61M1/14
摘要： PURPOSE:To simplify the constitution of a circuit and to reduce a blood filling amount, by dividing a box-shaped housing into upper and lower parts by a partition wall and providing a heat exchange chamber and a gas exchange chamber above the partition wall and providing a blood storage tank under the partition wall. CONSTITUTION:The interior of a housing is divided into upper and lower parts by a partition wall 4, and a heat exchange chamber 1 and a gas exchange chamber 2 are formed above the partition wall 4 and a blood storage tank 3 is formed under the partition wall 4. The gas such as oxygen or air supplied from a gas inflow port 10 is made flowable through hollow yarns 6 and the blood supplied from a blood inlet port 14 is immediately introduced into the heat exchange chamber 1 and allowed to flow around fine tubes 5 through which a heat exchange medium flows to perform heat exchange and pref. introduced into the gas exchange chamber 2 through a perforated plate 18 and allowed to flow around the hollow yarns 6 through which the gas flows to perform gas exchange and subsequently introduced into the blood storage tank 3. A blood communication opening 23 for supplying the blood after gas exchange to the blood storage tank is provided at the upper part of the gas exchange chamber 2.

6. 发明专利

JPS60232204A COMPOSITE HOLLOW YARN SEPARATION MEMBRANE, PREPARATION AND USE THEREOF 失效
公开(公告)号：JPS60232204A
公开(公告)日：1985-11-18
申请号：JP8818984
申请日：1984-04-30
申请人： KURARAY CO
发明人： OOYABU SHIYUUZOU , KAWAI SHIYUUJI , OKAMOTO TAKEHIKO , MIGAKI TAKAO
IPC分类号： A61M1/18 , A61M1/16 , B01D69/08 , B01D71/68
摘要： PURPOSE:To provide a highly permeable composite hollow yarn separation membrane having an extremely thin selective separation layer, obtained by arranging a selective separation layer, an extremely microporous layer and a porous layer successively from the inner side of a hollow yarn. CONSTITUTION:A selective separation layer 1 with an average thickness of 0.01-2mum is formed to the inner surface of a composite hollow yarn separation membrane. The polyner constituting this selective separation layer 1 is formed so as not to be substantially penetrated into a microporous layer 2. When a polysiloxane system is used as the polymer, an oxygen enriched membrane or an artificial lung is pref. obtained. The extremely microporous layer is formed in a thickness of 0.08mum or less so as to be adjacent to the selective separation layer 1. Fluid permeability of said layer 2 requires 10 times that of the selective separation layer 1. A porous layer 3 with a thickness of 10-500mum is formed so as to be adjacent to the extremely fine porous layer 2. This layer has a spong structure provided with pores having a pore size of 0.1-1mum and the void ratio thereof is pref. 50% or more.

7. 发明专利

JPS5840111A PREPARATION OF COMPOSITE SEPARATION MEMBRANE 失效
公开(公告)号：JPS5840111A
公开(公告)日：1983-03-09
申请号：JP13728281
申请日：1981-08-31
申请人： KURARAY CO
发明人： OOYABU SHIYUUZOU , KAWAI SHIYUUJI , OKAMOTO TAKEHIKO , MIGAKI TAKAO
IPC分类号： C08J9/26 , B01D53/22 , B01D69/10 , B01D69/14 , D06M11/00 , D06M13/144 , D06M23/00 , D06M101/00 , D06M101/02 , D06M101/06 , D06M101/16 , D06M101/18 , D06M101/20 , D06M101/22 , D06M101/24 , D06M101/30
摘要： PURPOSE:To prepare a composite separation membrane having an extremely large permeation area per a unit volume, by a method wherein an ultra-thin membrane is homogenously prepared from high molecular components and at least one component in the resulting membrane substrate is removed from a surface opposed to the high molecular components. CONSTITUTION:In order to obtain a non-porous membrane substrate prepared by molding a uniform mixture consisting of a removing component and a non-removing component, a comman solvent having high compatibility with both of them is used. The non-porous surface of the substrate, that is, the surface opposed to a surface having highly selectively separation permeability to a specific substance is contacted with, for example, water to extract and remove polyethylene glycol or polyvinyl pyrrolidone. By this way, a hollow yarn composite separation membrane comprising a high molecular ultra-thin membrane formed on one surface of the porous hollow yarn substrate is obtained. The ratio of the total non-removing residual component and the total removing component is pref. 100:25-100:200. As the residual component, a wide-ranging high molecular substance such as PVA or aromatic polysulfone is used.

8. 发明专利

JPS57113808A MOUNTING METHOD OF HOLLOW FIBER 失效
公开(公告)号：JPS57113808A
公开(公告)日：1982-07-15
申请号：JP18633580
申请日：1980-12-30
申请人： KURARAY CO
发明人： AKASU HIROYUKI , MIGAKI TAKAO , KAWAI SHIYUUJI
IPC分类号： B01D63/02
摘要： PURPOSE:To decrease the generation rate of leakage in hollow fiber parts by waterproofing and covering both end parts of the hollow fibers to be fixed to a device beforehand prior to wetting. CONSTITUTION:For example, both ends of a hollow fiber bundle 1 are cut uniformly, and fiber opening parts are opened by quick setting type epoxy adhesive and are inserted into the casing 4 of a selective permeable device. Pots 9, 10 coated with release agents are mounted to the casing, after which urethane adhesive is supplied into the pots 9, 10 through inlets 7, 8 under effecting of centrifugal force. A projection 13 is provided to the pot 10 to avoid securing of end parts 12 to the casing 4. After setting of the adhesive, the pots 9, 10 are removed, and the bundle 1 of the end parts 11 adhered and fixed to the casing 4 and the end parts 12 which are simply covered is obtained. After immersing in warm water, it is lightly centrifugally dehydrated to remove excess water in the fiber parts, the water stuck in the casing and the water drops in the end parts 12, after which the pot 9 is mounted to the end part 12 side, and said end parts are adhered and fixed to the casing 4 in the same manner as mentioned above.

9. 发明专利

JPH054125B2 失效
公开(公告)号：JPH054125B2
公开(公告)日：1993-01-19
申请号：JP8818984
申请日：1984-04-30
申请人： KURARAY CO
发明人： OOYABU SHUZO , KAWAI SHUJI , OKAMOTO TAKEHIKO , MIGAKI TAKAO
IPC分类号： A61M1/18 , A61M1/16 , B01D69/08 , B01D71/68

10. 发明专利

JPH0335971B2 失效
公开(公告)号：JPH0335971B2
公开(公告)日：1991-05-30
申请号：JP3330483
申请日：1983-02-28
申请人： KURARAY CO
发明人： OOYABU SHUZO , KAWAI SHUJI , OKAMOTO TAKEHIKO , MIGAKI TAKAO
IPC分类号： D01F8/04 , B01D69/02 , B01D69/08 , B01D69/12 , B01D71/68 , B01D71/70 , D06M15/643 , D06M101/00 , D06M101/16 , D06M101/30

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