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1. 发明专利

JP2003065905A Method and apparatus for sampling sample 有权
标题翻译：采样方法和装置
公开(公告)号：JP2003065905A
公开(公告)日：2003-03-05
申请号：JP2001253379
申请日：2001-08-23
申请人： Hitachi Ltd , Hitachi Sci Syst Ltd , National Institute Of Advanced Industrial & Technology , 株式会社日立サイエンスシステムズ , 株式会社日立製作所 , 独立行政法人産業技術総合研究所
发明人： UKIANA MOTOHIDE , FUJII KAZUHIRO , MORITA KAZUHIRO , ISAGOZAWA SHIGETO , KOIKE HIDEMI , TANIGAWA TAMIO , KOYANAI NORIO
IPC分类号： G01N1/00 , B25J7/00 , G01N1/28
摘要： PROBLEM TO BE SOLVED: To accurately perform sampling work of a sample piece performed after the sample piece is formed by focusing ion beam in the atmosphere at a low cost by a simple method, to realize the high magnification observation of TEM and to also enable the additional processing of the sample piece.
SOLUTION: After the fine sample piece is formed by irradiating a sample substrate 38 with focusing ion beam, the sample substrate 38 is fed to the region under an optical microscope 1 in the atmosphere and a micromanipulator 10 having a plurality of finger pieces at least one of which can perform fine three- degree-of-freedom operation is used under the optical microscope 1 to extract the sample piece from the sample substrate 38 to fix the same to a grid for transmission electron microscope observation.
COPYRIGHT: (C)2003,JPO
摘要翻译：要解决的问题：为了通过简单的方法以低成本将离子束聚焦在大气中而形成样品片之后进行的样品的取样工作，为了实现TEM的高倍率观察，附加处理样品。解决方案：在通过用聚焦离子束照射样品基板38形成细样品之后，将样品基板38送入大气中的光学显微镜1下的区域，并且具有多个手指片的显微操纵器10至少一个在光学显微镜1下使用可以进行精细的三自由度的操作，从样品基板38提取样品片，将其固定到用于透射电子显微镜观察的栅格。

2. 发明专利

JP2003062773A Micromanipulator 有权
标题翻译：微机
公开(公告)号：JP2003062773A
公开(公告)日：2003-03-05
申请号：JP2001253389
申请日：2001-08-23
申请人： Hitachi Ltd , Hitachi Sci Syst Ltd , National Institute Of Advanced Industrial & Technology , 株式会社日立サイエンスシステムズ , 株式会社日立製作所 , 独立行政法人産業技術総合研究所
发明人： MORITA KAZUHIRO , UKIANA MOTOHIDE , FUJII KAZUHIRO , ISAGOZAWA SHIGETO , KOIKE HIDEMI , TANIGAWA TAMIO
IPC分类号： G02B21/32 , B25J7/00 , B25J17/02
CPC分类号： B25J17/0266 , B25J7/00 , B25J9/0015 , Y10T29/53 , Y10T74/20335 , Y10T74/20341
摘要： PROBLEM TO BE SOLVED: To provide a three-freedom micromanipulator capable of carrying out easy and precise positioning, wherein a link mechanism of the micromanipulator having translational three-freedom as its main action is formed by a structure in which a solid plate is bent and stamped. SOLUTION: A base member 2 and an end effector 3 are connected by a three-link mechanism 6 which are formed by bending and stamping a flexible plate. A plate-type arm part 6' has a width in the direction around the shaft of the end effector. Hinge parts 6b and 6f which form a rotating kinematic pair R are formed at both ends of the longitudinal direction of respective arm parts 6'. Hinge parts 6d which form the rotating kinematic pair R are also formed in a middle part. Parallelogram links 6c which form a translation kinematic pair P is formed between one end and middle part of the longitudinal direction of the arm part 6'.
摘要翻译：要解决的问题：提供一种能够进行容易且精确定位的三自由度显微操纵器，其中具有作为其主要作用的平移三自由度的显微操纵器的连杆机构由固体板弯曲的结构形成，盖章。解决方案：通过弯曲和冲压柔性板形成的三连杆机构6连接底座件2和端部执行器3。板状臂部6'具有围绕端部执行器的轴的方向的宽度。形成旋转运动对R的铰链部6b，6f形成在各臂部6'的长度方向的两端。形成旋转运动对R的铰链部6d也形成在中间部。在臂部6'的长度方向的一端部和中间部之间形成有形成平移四边形运动对P的平行四边形连杆6c。

3. 发明专利

JP2004090136A Micro hand 有权
公开(公告)号：JP2004090136A
公开(公告)日：2004-03-25
申请号：JP2002253453
申请日：2002-08-30
申请人： Hitachi High-Technologies Corp , Hitachi Sci Syst Ltd , National Institute Of Advanced Industrial & Technology , 株式会社日立サイエンスシステムズ , 株式会社日立ハイテクノロジーズ , 独立行政法人産業技術総合研究所
发明人： UKIANA MOTOHIDE , FUJII KAZUHIRO , MORITA KAZUHIRO , ISAGOZAWA SHIGETO , KOIKE HIDEMI , TANIGAWA TAMIO
IPC分类号： G02B21/32 , B25J7/00 , B25J11/00 , B81B7/02
摘要： PROBLEM TO BE SOLVED: To provide a micro hand, small-sized, costing low, and exhibiting a high-accuracy function.
SOLUTION: This micro hand includes end effectors 3, 14 having finger pieces 4, 5. The effector 3 is disposed to penetrate inside the effector 14. At least one of the effectors 3, 14 is connected to a base 2 through three link mechanisms 6, 7. The central parts (the top part) of the link mechanisms 6, 7 are connected to the lower surfaces of the corresponding end effectors, and expanded in three ways from the centers of the end effectors 6, 7 with the midway to the tip extending along the outer surface of the base 2. In the base 2, a plate-like arm 8 forming a part of each link mechanism 6, 7 is expanded from the upper surface of the base toward the link mechanisms 6, 7, and the midway to the tip is extended along the outer surface of the base. The plate-like arm 8 is connected to the link mechanisms 6, 7, and integrally formed. A piezoelectric element 90 for operating the link mechanisms is disposed in the base 2.
COPYRIGHT: (C)2004,JPO

4. 发明专利

JP2008021657A Micromanipulator 有权
标题翻译：显微操纵器
公开(公告)号：JP2008021657A
公开(公告)日：2008-01-31
申请号：JP2007220067
申请日：2007-08-27
申请人： Hitachi High-Tech Science Systems Corp , Hitachi Ltd , National Institute Of Advanced Industrial & Technology , 株式会社日立ハイテクサイエンスシステムズ , 株式会社日立製作所 , 独立行政法人産業技術総合研究所
发明人： UKIANA MOTOHIDE , MORITA KAZUHIRO , FUJII KAZUHIRO , TANIGUCHI YOSHIFUMI , KOYANAI NORIO , TANIGAWA TAMIO
IPC分类号： H01J37/20 , B25J7/00 , B25J11/00
摘要： PROBLEM TO BE SOLVED: To perform fine manipulations to a biological sample under electronic rays in vacuum of an electron microscope.
SOLUTION: The manipulator 10 capable of minute rotation, displacement, and opening action holding a minute sample is provided in a vacuum sample chamber 2 of an electron microscope. The manipulator 10 is a translation 3 degree-of freedom type. It is provided with a positioning adjustment mechanism 5 positioning the manipulator 10 to an optical axis, a needle point matching mechanism 12 operating a minute needle point of the manipulator in the sample chamber to be matched from outside monitoring with an electron microscope monitor, and a lead wire pulling hole 95 pulling out a lead wire for power supply and electric signal detection from the sample chamber outside with airtightness retained. The positioning adjustment mechanism, the operation part of the needle point matching mechanism and the lead wire pulling hole are intensively fitted on a flange 71, the flange is attached on an attaching hole 96 of a wall part of the sample chamber by airtight sealing.
COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：在电子显微镜的真空中在电子射线下对生物样品进行精细的操作。解决方案：在电子显微镜的真空样品室2中设置能够保持微小样品的微小旋转，位移和开启动作的操纵器10。操纵器10是翻译3自由度类型。设置有将操纵器10定位在光轴上的定位调节机构5，利用电子显微镜监视器对从样本室中的操纵器的微小针尖进行操作以与外部监视匹配的针点匹配机构12，以及引线拉出孔95从外部的样品室拉出用于供电的电线和电信号检测，保持气密性。定位调节机构，针尖匹配机构的操作部和引线牵引孔集中装配在凸缘71上，通过气密密封将凸缘安装在样品室的壁部的安装孔96上。版权所有（C）2008，JPO＆INPIT

5. 发明专利

JP2007118131A Thin plate hinge positioning device by shape memory alloy 审中-公开
标题翻译：薄板铰链定位装置通过形状记忆合金
公开(公告)号：JP2007118131A
公开(公告)日：2007-05-17
申请号：JP2005313814
申请日：2005-10-28
申请人： National Institute Of Advanced Industrial & Technology , 独立行政法人産業技術総合研究所
发明人： TANIGAWA TAMIO
IPC分类号： B25J7/00 , B81B3/00
摘要： PROBLEM TO BE SOLVED: To provide a small highly accurate positioning device of a wide operation range without using a piezoelectric element as a driving means of a link mechanism for driving an operation part that moves minutely.
SOLUTION: A passive joint member 1 is provided with a plurality of arms to form a hinge by cutting and bending by using a thin plate made of a shape memory alloy to maintain superelasticity since the alloy has a transformation temperature or more when used. A driving joint member 2 is provided with a plurality of arms formed by the thin plate made of a shape memory alloy. The shape memory alloy forming the passive joint member 1 is formed by a material to transform at a lower temperature than the transformation temperature of the shape memory alloy forming the driving joint member 2. The plurality of arms of the driving joint member 2 are provided with heating means. By heating an arbitrary heating means of the arm, the operation part is positioned via the passive joint member 1 by transformation of the shape memory alloy. At the time, the passive joint member 1 is easily and largely deformed by superelasticity and is returned to its original state.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种宽范围的操作范围的小型高精度定位装置，而不使用压电元件作为用于驱动微小移动的操作部件的连杆机构的驱动装置。解决方案：被动接头构件1设置有多个臂，以通过使用由形状记忆合金制成的薄板进行切割和弯曲来形成铰链，以保持超弹性，因为当使用合金时具有相变温度或更高的合金。驱动接头构件2设置有由形状记忆合金制成的薄板形成的多个臂。形成被动接头构件1的形状记忆合金由形成驱动接合构件2的形状记忆合金的相变温度以下的温度变形的材料形成。驱动接合构件2的多个臂设置有加热方式。通过加热臂的任意加热装置，通过形状记忆合金的转变，通过被动接头构件1定位操作部。此时，被动接合构件1由于超弹性容易且大幅度地变形，并返回到其原始状态。版权所有（C）2007，JPO＆INPIT

6. 发明专利

JP2004181538A Method for forming minute structure and device used for the same 有权
公开(公告)号：JP2004181538A
公开(公告)日：2004-07-02
申请号：JP2002347894
申请日：2002-11-29
申请人： National Institute Of Advanced Industrial & Technology , 独立行政法人産業技術総合研究所
发明人： TANIGAWA TAMIO , MATSUURA HIROSHI , FURUKAWA SUKEMITSU , UDA TAKESHI
IPC分类号： B81C99/00 , G01Q60/24 , G01Q60/50 , G01Q60/52 , G01Q70/00 , G01Q80/00 , B81C5/00 , G01N13/22
摘要： PROBLEM TO BE SOLVED: To provide a method for forming and stabilizing a minute structure of a selectable material in an intended position of a selectably processed surface, and also provide a device used for the same. SOLUTION: A means for forming the minute structure comprises mounting a material 3 for forming a meniscus on a processed surface of a substrate for forming the minute structure; installing a sharpened probe 4 opposed to the material 3 for forming the meniscus; installing an electromagnetic field applying means 8 to induce mutual electromagnetic operation between the processed surface and material 3 for forming the meniscus and the sharpened probe; and installing a curing means to cure the meniscus formed between the processed surface and the sharpened probe, in the device for forming a minute object by inducing a liquid meniscus of the selectable material on the processed surface. COPYRIGHT: (C)2004,JPO&NCIPI

7. 发明专利

JP2009142251A Cutting device of cell flowing through minute fluidic path of micro fluidic chip, micro fluidic chip and cell cutting method 有权
标题翻译：通过微流化芯片，微流化芯片和细胞切割方法的微小流路的细胞流动的切割装置
公开(公告)号：JP2009142251A
公开(公告)日：2009-07-02
申请号：JP2007326073
申请日：2007-12-18
申请人： National Agriculture & Food Research Organization , National Institute Of Advanced Industrial & Technology , 独立行政法人産業技術総合研究所 , 独立行政法人農業・食品産業技術総合研究機構
发明人： ICHIKAWA AKIHIKO , TANIGAWA TAMIO , OBA KOTARO , TAKAHASHI SEIYA
IPC分类号： C12M1/00 , G01N35/10 , G01N37/00
CPC分类号： C12M47/06
摘要： PROBLEM TO BE SOLVED: To enable surely cutting cells by utilizing merit of micro fluidic chips to make cell restoration easy. SOLUTION: When a drawn cell monitored with a cell image-acquiring means is drawn with a cell-drawing means to a cell-drawing micro fluidic path so that a branch part cell-holding state is formed, in which state a part of the cell is positioned at the cell-drawing micro fluidic path side and the other part of the cell remains in the micro fluidic path side, the cell is cut at the opening part of the branch part by flowing a cutting fluid through the micro fluidic path. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：通过利用微流体芯片的优点，确保切割细胞，使细胞恢复容易。解决方案：当用细胞图像获取装置监视的绘制细胞用细胞拉伸装置绘制到细胞绘制微流体路径，从而形成分支部分细胞保持状态，其中部分的细胞位于细胞提取微流体路径侧，细胞的另一部分保留在微流体路径侧，通过使切割流体流过微流体，在分支部分的开口部分处切割细胞路径。版权所有（C）2009，JPO＆INPIT

8. 发明专利

JP2004325089A Capture device and capture method for minute object 有权
公开(公告)号：JP2004325089A
公开(公告)日：2004-11-18
申请号：JP2003116362
申请日：2003-04-21
申请人： High Energy Accelerator Research Organization , National Institute Of Advanced Industrial & Technology , 独立行政法人産業技術総合研究所 , 高エネルギー加速器研究機構長
发明人： WAKATSUKI SOICHI , HIRAKI MASAHIKO , NAGAI MINORU , TANIGAWA TAMIO
IPC分类号： G01N1/04 , B01L99/00 , B25J7/00 , G01N15/00 , G01N15/14 , G01N35/00
CPC分类号： G01N35/0099 , G01N15/1463 , G01N2015/0096 , G02B21/32 , Y10T436/25375
摘要： PROBLEM TO BE SOLVED: To realize a capture device and a capture method, capable of easily, certainly and efficiently executing a loop charging of a minute object such as a protein crystal. SOLUTION: In this capture device, the crystal 1 inside a droplet 2 placed in a prescribed position on a base 3 is grasped by a grasp mechanism 4, the crystal 1 grasped by the grasp mechanism 4 is captured by a capture mechanism 5, and the captured crystal 1 is separated from the droplet 2. COPYRIGHT: (C)2005,JPO&NCIPI

9. 发明专利

JP2009055816A Microfluidic chip apparatus, microfluidic chip and tube for feeding fluid used for this as well as method for introducing and deriving sample 有权
标题翻译：微流控芯片设备，微流控芯片和用于进料流体的导管用于引入和衍生样品的方法
公开(公告)号：JP2009055816A
公开(公告)日：2009-03-19
申请号：JP2007224761
申请日：2007-08-30
申请人： National Institute Of Advanced Industrial & Technology , 独立行政法人産業技術総合研究所
发明人： TANIGAWA TAMIO , ICHIKAWA AKIHIKO
IPC分类号： C12M1/00 , B81B1/00 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To make injection of a sample, for example, a culture solution, cells or the like into a flow path formed in a microfluidic chip and also to improve the success rate of injection. SOLUTION: A hole for a tube connecter is formed in the oblique direction with respect to the flow path, and a first tube is arranged in the obliquely formed hole for the tube connector. A second tube which is finer than the first tube is arranged in the first tube so that it may be protruded form the end of the first tube on the side of the flow path for forming a fluid feed-in tube. COPYRIGHT: (C)2009,JPO&INPIT

10. 发明专利

JP2008306871A Angled facet accumulation drive 审中-公开
标题翻译： ANGLED FACET积累驱动
公开(公告)号：JP2008306871A
公开(公告)日：2008-12-18
申请号：JP2007153056
申请日：2007-06-08
申请人： National Institute Of Advanced Industrial & Technology , 独立行政法人産業技術総合研究所
发明人： TANIGAWA TAMIO , TOMOKUNI NOBUYASU , TOMIZAWA TETSUO , OHARA KENICHI , ICHIKAWA AKIHIKO , OBA KOTARO
IPC分类号： H02N2/00 , B25J11/00
摘要： PROBLEM TO BE SOLVED: To materialize a flat-surface integrated drive mechanism which is formed in a sheet form by integrating a plurality of multi-flexibility drive mechanisms largely and is capable of facilitating manufacture only by press processing. SOLUTION: The flat surface integrated drive mechanism 1 is provided with the plurality of multi-flexibility drive mechanisms 3 on a substrate 2. The substrate 2 is formed by punching a flexible metal plate, and is formed of hexagonal meshes in which a plurality of hexagonal frames 4 are continuously formed. The plurality of corner parts 5 of each hexagonal mesh are formed by three mesh frames 6, 7, 8 which are mutually crossed and have extensions 9, 10, 11. The multi-flexibility drive mechanism 3 includes a multi-flexibility drive member and a drive device. The multi-flexibility drive member has a central portion 15, and three legs 16, 17, 18 which extend in a radial direction from the central portion 15 and of which one edge is fixed at the extensions 9, 10, 11 respectively. The drive device enables the multi-flexibility drive mechanism 3 to move at three levels of flexibility by diving so that the three extensions 9, 10, 11 may be bent from the base edge portion on the corner portions 5, respectively. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：通过大量整合多个多柔性驱动机构来实现以片状形成的平面一体式驱动机构，并且能够仅通过冲压加工便于制造。解决方案：平面一体化驱动机构1在基板2上设置有多个多柔性驱动机构3.基板2通过冲压柔性金属板而形成，并且由六边形网格形成，其中连续地形成多个六边形框架4。每个六边形网格的多个拐角部分5由相互交叉并具有延伸部9,10,11的三个网眼框架6,7,8形成。多柔性驱动机构3包括多柔性驱动构件和驱动装置。多柔性驱动构件具有中心部分15和从中心部分15沿径向方向延伸的三个支腿16,17,18，并且其中一个边缘分别固定在延伸部9,10,11处。驱动装置使得多柔性驱动机构3能够通过潜水以三个灵活性水平移动，使得三个延伸部9,10,11可以分别从拐角部分5上的基部边缘部分弯曲。版权所有（C）2009，JPO＆INPIT

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