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1. 发明专利

JP2015048940A 活栓駆動装置およびそれを用いた薬剤製造装置审中-公开
标题翻译：停止COCK驱动装置和使用该装置的药物生产装置
公开(公告)号：JP2015048940A
公开(公告)日：2015-03-16
申请号：JP2013183507
申请日：2013-09-04
申请人：株式会社日立製作所 , Hitachi Ltd
发明人： FURUKAWA AKIHIRO , SUGAYA MASAKAZU , HARADA KUNIO , KUNO NORITO , MURATA HISASHI
IPC分类号： F16K31/524
CPC分类号： F15B15/06 , F16H25/12 , F16K31/528
摘要：【課題】活栓の流路の自動切り替え、および回転角度の位置を検出する。【解決手段】外周面にループ状の溝102が形成され、正逆方向に回転自在な円筒カム101と、それぞれ溝102に配置され、直線往復運動可能な2つの駆動ピン103,104と、円筒カム101に接続され、流路を切り替える三方活栓403aと、2つの駆動ピン103,104を円筒カム101の延在方向に沿った方向に直線往復運動させて、円筒カム101をその回転の中心Cに対して正または逆方向に回転させることで三方活栓403aの上記流路を切り替える制御部110と、を有している。【選択図】図1
摘要翻译：要解决的问题：自动切换停止旋塞的流路并检测旋转角度的位置。解决方案：止动销驱动装置包括：圆柱形凸轮101，其外周上具有环状凹槽102 形成并能够在正反方向旋转; 两个驱动销103,104分别布置在槽102中并且可以向前和向后线性地移动; 连接到圆筒形凸轮101并切换流动通道的三通止动螺栓403a; 以及控制部110，用于通过使两个驱动销103,104在沿着圆柱形凸轮101的延伸方向的方向上向前和向后线性地移动并将圆柱形凸轮101旋转到三通止动销403a的流动通道在正常或反向的旋转中心C。

2. 发明专利

JP2015052383A 運動方向変換機構およびそれを用いたアクチュエータ、薬剤製造装置审中-公开
标题翻译：运动方向转换机构，以及使用其的执行器和药物制造设备
公开(公告)号：JP2015052383A
公开(公告)日：2015-03-19
申请号：JP2013186757
申请日：2013-09-09
申请人：株式会社日立製作所 , Hitachi Ltd
发明人： HARADA KUNIO , FURUKAWA AKIHIRO , SUGAYA MASAKAZU , KUNO NORITO , MURATA HISASHI
IPC分类号： F16H25/12 , A61J3/00 , F15B15/06
CPC分类号： F16K11/0853 , F16H25/12 , Y10T74/18312 , Y10T137/86871
摘要：【課題】活栓を用いた流路の切り替えにおけるカムの回転方向の選択が可能であり、確実に90度毎に回転・停止を行う。【解決手段】三方活栓201が接続されるカム206の溝212に沿って直進運動するピン214と、回転運動を行うカム206と、ピン214をカム206の延在方向に沿って直進運動させ、かつカム206をその回転の中心軸211に対して回転させることで三方活栓201の流路を切り替える制御部とを有し、溝212を形成する第1、第2、第3および第4の溝は繋がった形状であり、第1の傾斜角度と第3の傾斜角度は傾斜の向きが中心軸211に対して逆であり、かつ第2の傾斜角度と第4の傾斜角度は傾斜の向きが中心軸211に対して逆であるアクチュエータ。【選択図】図3
摘要翻译：要解决的问题：提供一种移动方向转换机构，其允许在使用停止旋塞切换通道时选择凸轮的旋转方向，并且可以每90°可靠地执行旋转/停止。解决方案：致动器包括：销 214，其沿着三通止动旋塞201连接到的凸轮206的凹槽212进行直线运动; 执行旋转运动的凸轮206; 并且使销214沿着凸轮206的延伸方向直线运动的控制部分使凸轮206围绕旋转的中心轴211旋转，从而切换三通止动凸轮201的通道形成凹槽212的第一，第二，第三和第四凹槽具有彼此接合的形状，第一倾斜角度和第三倾斜角度的倾斜方向相对于中心轴211反向，并且倾斜第二倾斜角度和第四倾斜角度的方向相对于中心轴211反向。

3. 发明专利

JP2008263394A Remote control monitoring system 审中-公开
标题翻译：远程控制监控系统
公开(公告)号：JP2008263394A
公开(公告)日：2008-10-30
申请号：JP2007104387
申请日：2007-04-12
申请人： Hitachi Ltd , 株式会社日立製作所
发明人： KUNO NORITO
IPC分类号： H04N5/232 , H04N5/225
摘要： PROBLEM TO BE SOLVED: To provide a remote control monitoring system capable of easily and accurately providing an instruction by an operation instruction method including three-dimensional information.
SOLUTION: An operation setting part 2 displays image data of a subject 15 which is output from a subject operation part 1 on a first display part 21, and an adjustment condition setting means 24 executes condition setting, analyzes an observation area condition and an adjustment condition from an image picked up by an operation setting image pickup part 22 and determines the observation area condition and the adjustment condition. Two-dimensional image data are displayed on a second display part 17 on the basis of the observation area condition and the adjustment condition, an irradiation position and an angle of a light irradiating light source 13 are set and light irradiation is performed on a position and at an angle corresponding to the observation area condition and the adjustment condition of the subject to instruct operation contents from a remote place.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种能够通过包括三维信息的操作指令方法容易且准确地提供指令的遥控监视系统。解决方案：操作设置部分2显示在第一显示部分21上从主体操作部分1输出的对象15的图像数据，并且调整条件设置装置24执行条件设置，分析观察区域条件和从由操作设置图像拾取部分22拾取的图像的调整条件，并确定观察区域条件和调整条件。基于观察区域条件和调整条件，设置照射位置和照射光源13的角度，将二维图像数据显示在第二显示部分17上，并且对位置进行光照射，并且以对应于观察区域条件和对象的调整条件的角度指示来自远程地方的操作内容。版权所有（C）2009，JPO＆INPIT

4. 发明专利

JP2006153785A Solution stirring device and analyzing system 审中-公开
标题翻译：解决方案搅拌装置和分析系统
公开(公告)号：JP2006153785A
公开(公告)日：2006-06-15
申请号：JP2004347986
申请日：2004-12-01
申请人： Hitachi Ltd , 株式会社日立製作所
发明人： KUNO NORITO , ISHIBASHI MASAYOSHI
IPC分类号： G01N35/02 , C12M1/02 , C12M1/40 , G01N33/53 , G01N33/566 , G01N37/00
CPC分类号： B01F11/0045 , B01F13/0059 , B01L3/502 , B01L3/5027 , B01L2300/0636 , B01L2300/0822 , B01L2400/0481
摘要： PROBLEM TO BE SOLVED: To provide an analyzing apparatus and detecting system having a stirring method that do not require a complex device mechanism, attain homogeneous stirring and mixing of reaction liquid in the whole region on a slide glass substrate, and have high reaction efficiency.
SOLUTION: A lid member having a recessed part for forming a space for holding the substrate and reaction liquid is constituted by a deformable material, the lid member is deformed by acting a force from the outside of the lid member, and the reaction liquid is stirred in the space by moving the reaction liquid fed into the reaction space due to the deformation in the space. The signal intensity is increased by improvement of the reaction efficiency by the stirring. Any position of the lid member can be deformed, so that homogeneous stirring in the whole region of the reaction space can be attained.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：解决问题的方案为了提供一种不需要复杂的装置机构的搅拌方法的分析装置和检测系统，在载玻片基板上的整个区域中均匀地搅拌和混合反应液，并且具有高的反应效率。解决方案：具有用于形成用于保持基板和反应液的空间的凹部的盖构件由可变形材料构成，盖构件通过从盖构件的外部施加力而变形，并且反应液体在空间中被搅动，由于空间中的变形而使进入反应空间的反应液移动。通过搅拌提高反应效率来提高信号强度。盖构件的任何位置都可以变形，从而能够在反应空间的整个区域中均匀地搅拌。版权所有（C）2006，JPO＆NCIPI

5. 发明专利

JP2003315337A Circulation type biochemical reaction apparatus 审中-公开
标题翻译：循环型生化反应装置
公开(公告)号：JP2003315337A
公开(公告)日：2003-11-06
申请号：JP2002220604
申请日：2002-07-30
申请人： Hitachi Ltd , 株式会社日立製作所
发明人： KUNO NORITO , UCHIDA NORITAKA
IPC分类号： G01N33/53 , C12M1/00 , G01N33/566 , G01N35/08 , G01N37/00
CPC分类号： B01L2400/086
摘要： PROBLEM TO BE SOLVED: To provide a circulation type biochemical reaction apparatus capable of generating a hybridization reaction efficiently and uniformly. SOLUTION: A plate member 5 where a passage 6 for circulating a sample solution, an inflow port 7, an outflow port 8 and a projection 9 for straightening are formed, and a plate member 7 where a recessed part 3 for holding a probe substrate 1 is formed are bonded in piles to form an aggregate, and the aggregate is arranged in a tilted state against a horizontal plane so that the inflow port 7 is positioned on the lower side of the outflow port 8. The sample solution is fed from the inflow port 7, injected into the passage, and circulated. Thus, the signal intensity is enhanced, and a reaction time is shortened by improvement of the reaction efficiency by circulation. In addition, since the reaction proceeds uniformly, quantitativeness of the signal intensity is improved. COPYRIGHT: (C)2004,JPO
摘要翻译：要解决的问题：提供能够有效且均匀地产生杂交反应的循环型生化反应装置。＆lt; P＆gt;解决方案：一个板构件5，其中形成有用于循环样品溶液的通道6，流入口7，流出口8和用于矫直的突出部9;板构件7，其中用于保持探针基板1被形成为堆叠以形成聚集体，并且聚集体相对于水平面以倾斜状态布置，使得流入口7位于流出端口8的下侧。样品溶液被供给从流入口7注入通道并循环。因此，信号强度提高，并且通过循环提高反应效率来缩短反应时间。此外，由于反应均匀地进行，信号强度的定量提高。版权所有（C）2004，JPO

6. 发明专利

JP2009300349A Avidins bonding carrier, manufacturing method therefor and method for use 有权
标题翻译： AVIDINS BONDING CARRIER，制造方法及其使用方法
公开(公告)号：JP2009300349A
公开(公告)日：2009-12-24
申请号：JP2008157469
申请日：2008-06-17
申请人： Hitachi Ltd , 株式会社日立製作所
发明人： OZAWA OSAMU , TADA HIROKO , KUNO NORITO
IPC分类号： G01N33/53 , G01N33/543 , G01N33/547
摘要： PROBLEM TO BE SOLVED: To attain a superior stability by reducing nonspecific adsorption of foreign substances such as proteins and the like.
SOLUTION: A biotin compound and a nonionic/hydrophilic compound are bonded respectively with a surface functional group existing on a carrier surface, and then avidins are bonded with the biotin compound being bonded with the carrier surface. The nonionic/hydrophilic compound preferably has a chemical structure having a functional group bondable with the surface functional group and polyethylene oxide. In addition, the polyethylene oxide is preferably composed of four or more cycle number of ethylene oxide.
COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：通过减少诸如蛋白质等异物的非特异性吸附来获得优异的稳定性。解决方案：生物素化合物和非离子/亲水化合物分别与存在于载体表面上的表面官能团键合，然后将avidins与与载体表面结合的生物素化合物结合。非离子/亲水性化合物优选具有具有与表面官能团和聚环氧乙烷键合的官能团的化学结构。此外，聚环氧乙烷优选由四个以上环氧乙烷的循环数构成。版权所有（C）2010，JPO＆INPIT

7. 发明专利

JP2006006224A Method for managing cell and tissue culture and system therefor 有权
标题翻译：用于管理细胞和组织培养及其系统的方法
公开(公告)号：JP2006006224A
公开(公告)日：2006-01-12
申请号：JP2004188895
申请日：2004-06-25
申请人： Hitachi Ltd , 株式会社日立製作所
发明人： KUNO NORITO
IPC分类号： C12N15/09 , C12M3/00 , C12N5/07 , C12N5/071 , C12Q1/68 , G01N33/48 , G06F19/00 , G06F19/28
CPC分类号： C12M99/00
摘要： PROBLEM TO BE SOLVED: To provide a cell and tissue culture method and a system therefor that can detect the mistakes, picking up wrong cells or wrong tissues in the working course of the culture process and prevents the cultured cells or tissues of other than the donor from being used with mistake. SOLUTION: As cell or tissue information that is unseparable from the cell and tissue themselves, individual recognition of the cell donors, in other words, the cell or tissue information that can recognize the origin of the cultured cell groups or the tissue groups, the gene information held in the cell group or tissue group is utilized to compare and collate the gene information before the cultivation with that after the cultivation. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供一种能够检测错误的细胞和组织培养方法及其系统，在培养过程的工作过程中拾取错误的细胞或错误的组织，并防止其他培养的细胞或组织比捐赠者被误用。解决方案：作为与细胞和组织本身不可分离的细胞或组织信息，细胞供体的个体识别，换句话说，可以识别培养的细胞群或组织组的起源的细胞或组织信息使用保持在细胞组或组织组中的基因信息来比较和整理培养前的基因信息与培养后的基因信息。版权所有（C）2006，JPO＆NCIPI

8. 发明专利

JP2004236553A Micro carrier and cell culture apparatus using the same and cell culture method 审中-公开
公开(公告)号：JP2004236553A
公开(公告)日：2004-08-26
申请号：JP2003028074
申请日：2003-02-05
申请人： Hitachi Ltd , Hitachi Medical Corp , 株式会社日立メディコ , 株式会社日立製作所
发明人： OZAWA OSAMU , KUNO NORITO , UCHIDA NORITAKA
IPC分类号： C12M3/00 , C12N5/07 , C12N5/071 , C12N5/06
摘要： PROBLEM TO BE SOLVED: To provide a micro carrier which is used as a carrier for culturing anchorage-dependent cells and from which the cells can easily, massively, high efficiently and selectively be recovered. SOLUTION: The micro carrier 1 used as a carrier for culturing the anchorage-dependent cells is characterized in that at least one part of the surface of a particulate support 2 containing a magnetic material is coated with a temperature-sensitive resin 3. COPYRIGHT: (C)2004,JPO&NCIPI

9. 发明专利

JP2004229619A Culturing apparatus 有权
公开(公告)号：JP2004229619A
公开(公告)日：2004-08-19
申请号：JP2003025358
申请日：2003-02-03
申请人： Hitachi Ltd , Hitachi Medical Corp , 株式会社日立メディコ , 株式会社日立製作所
发明人： OZAWA OSAMU , NOMURA YASUSHI , SUZUKI TSUTOMU , OGINO SATOSHI , KOIKE KOICHI , ANDO YOSHINORI , KUNO NORITO , UCHIDA NORITAKA
IPC分类号： C12M1/00 , C12M1/12 , C12M1/34 , C12M1/36 , C12M3/00 , C12N5/06 , C12Q1/04 , G01N33/48 , G01N33/50
CPC分类号： G01N33/5002 , C12M37/00 , C12M41/14 , C12M41/36 , C12M41/46 , C12Q1/04
摘要： PROBLEM TO BE SOLVED: To provide a culturing apparatus for adhesion dependent cells capable of preventing the failure of culture caused by contamination. SOLUTION: This culturing apparatus is equipped with a mechanism for automatically detecting microorganisms in a culturing container, a mechanism for automatically eliminating the detected microorganisms and a mechanism automatically preventing recontamination. Thereby, it is possible to achieve a high level sterilization, prevent the failure of the culture by the contamination, and also prevent cells for transplanting and a tissue product from infection by pathogenic microorganisms. COPYRIGHT: (C)2004,JPO&NCIPI

10. 发明专利

JP2006325532A CELL CULTURE VESSEL, METHOD FOR PRODUCING THE SAME AND CULTURED CELL 审中-公开
公开(公告)号：JP2006325532A
公开(公告)日：2006-12-07
申请号：JP2005156551
申请日：2005-05-30
申请人： HITACHI LTD
发明人： KUWABARA KOSUKE , MIYAUCHI AKIHIRO , KUNO NORITO
IPC分类号： C12M3/00 , C12N5/06
摘要： PROBLEM TO BE SOLVED: To provide a cell culture vessel that has a simple structure, prevents damages of cells in release, promotes transportation of nutrients and discharge of waste matter and increases improvement effect on culture efficiency by the structure. SOLUTION: The cell cull vessel is equipped with a culture surface having a plurality of projections with corresponding diameters smaller than cells to be cultured in the culture vessel and side walls of the culture surface enclosing the culture surface in which a distance between an arbitrary position on a borderline between the side wall of the culture surface and the culture surface and the nearest projection is smaller than the diameters of cells to be cultured. The projections of the cell culture vessel more efficiently provide effects on cultured cells. COPYRIGHT: (C)2007,JPO&INPIT

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