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1. 发明专利

JP2012154886A Electrode for electrochemical measurement and electrochemical analyzer 有权
标题翻译：电化学测量电极和电化学分析仪
公开(公告)号：JP2012154886A
公开(公告)日：2012-08-16
申请号：JP2011016434
申请日：2011-01-28
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： KANEMOTO MASARU , AKABOSHI HARUO , YOSHIDA HIROSHI , IMAI KENTA , SAKAZUME TAKU
IPC分类号： G01N27/30 , G01N27/28 , G01N27/416
摘要： PROBLEM TO BE SOLVED: To realize an electrochemical analyzer having a working electrode less varied in an electrode surface state.SOLUTION: A working electrode 2, a counter electrode 3 and a reference electrode 4 are disposed in an electrolytic cell 1. The working electrode has a layered structure of a valve metal and platinum, a cross-sectional crystal structure along a thickness direction in a platinum portion is formed in the shape of layers on an electrode surface, and each layer of the platinum portion has a thickness of 5 micrometers or less. The electrodes 2, 3 and 4 are connected to potential applying means 5 and measuring means 6 through lead wires 7. A solution dispensing mechanism 11 introduces a measurement solution including a target chemical component from a measurement solution vessel 8 into a solution introducing tube 13 and introduces a buffer solution from a buffer vessel 9 into the solution introducing tube 13. The measurement solution and the buffer solution thus introduced are injected by a solution injecting mechanism 12 into the electrolytic cell 1 for electrochemical measurement of the target component.
摘要翻译：要解决的问题：实现电极表面状态的工作电极变化不大的电化学分析装置。解决方案：工作电极2，对电极3和参比电极4设置在电解池1中。工作电极具有阀金属和铂的层状结构，沿厚度的横截面晶体结构铂部分的方向形成为电极表面上的层的形状，并且铂层的每一层的厚度为5微米或更小。电极2,3和4通过引线7连接到电位施加装置5和测量装置6.溶液分配机构11将包括目标化学成分的测量溶液从测量溶液容器8引入溶液导入管13和将缓冲溶液从缓冲容器9引入到溶液导入管13中。将由此引入的测定溶液和缓冲溶液通过溶液注入机构12注入到用于目标成分的电化学测定的电解池1中。版权所有（C）2012，JPO＆INPIT

2. 发明专利

JP2008012858A Imprinting device and imprinting method 有权
标题翻译：印刷装置和印刷方法
公开(公告)号：JP2008012858A
公开(公告)日：2008-01-24
申请号：JP2006188369
申请日：2006-07-07
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： KUWABARA KOSUKE , ANDO TAKUJI , OGINO MASAHIKO , TADA YASUHIKO , YOSHIDA HIROSHI
IPC分类号： B29C59/02 , B82B3/00 , G11B5/84 , H01L21/027
CPC分类号： G03F7/0002 , B82Y10/00 , B82Y40/00 , G11B5/855 , H01L21/76817
摘要： PROBLEM TO BE SOLVED: To provide an imprinting device which can precisely transfer a pattern by preventing air bubbles from remaining between a stamper and an object to be transferred. SOLUTION: This imprinting device A1 is used for transferring the shape of the surface of the stamper 2 by bringing the object to be transferred 1 and the stamper 2 in contact with each other. The device A1 is equipped with a retaining means which retains the object to be transferred 1 and the stamper 2 apart from each other as specified, a pressure reducing means which reduces the internal pressure of a chamber holding the object to be transferred 1 and the stamper 2, and a position-adjusting means which adjusts the relative positions of the object to be transferred 1 and the stamper 2. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种能够通过防止气泡保持在压模和被转印物体之间来精确地传递图案的压印装置。解决方案：该压印装置A1用于通过使待传送物体1和压模2彼此接触来转印压模2的表面的形状。装置A1具有保持装置，该保持装置将待传送物体1和压模2按照规定彼此分开;减压装置，其减小保持待传送物体1的腔室和压模的内部压力调整被搬运物体1和压模2的相对位置的位置调整装置。（C）2008，JPO＆INPIT

3. 发明专利

JP2014163773A Nucleic acid analysis cartridge, method for manufacturing the same, and nucleic acid analyzer 有权
标题翻译：核酸分析盒，其制备方法和核酸分析仪
公开(公告)号：JP2014163773A
公开(公告)日：2014-09-08
申请号：JP2013034418
申请日：2013-02-25
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： AIDA KOHEI , YOSHIDA HIROSHI , NARAHARA MASATOSHI , SUGIMURA TEISHO , KIMURA RYUSUKE , NAKAZAWA TARO , YAMAZAKI MOTOHIRO
IPC分类号： G01N35/08 , G01N37/00
摘要： PROBLEM TO BE SOLVED: To provide a low-cost cartridge body which reduces mixture of contaminant and a membrane, and to provide a bonding process between the low-cost cartridge body and the membrane while suppressing a reduction in liquid feed accuracy and nucleic acid loss in liquid feed in a nucleic acid analysis cartridge.SOLUTION: In a nucleic acid analysis cartridge with a plurality of built-in reagents, reagent solution can be fed by non-contact liquid feed in a device using air pressure; as for bonding between a cartridge body and a membrane, direct bonding by deposition is performed; and materials with excellent deposition compatibility, high heat resistance, high chemical resistance, low water absorption, and low vapor transmission are selected for the materials of the cartridge and the membrane. Since bonding by deposition does not require introduction of different kinds of materials and formation of a polar functional group in the bonding, there is no fear of corrosion and nucleic acid adsorption by the reagent solution at a bonded part of the cartridge, and the bonding is at lower cost than that of other direct bonding processes.
摘要翻译：要解决的问题：提供一种降低污染物和膜的混合物的低成本筒体，并且在抑制液体进料精度和核酸损失降低的同时在低成本筒体与膜之间提供粘合工艺在核酸分析盒中的液体进料中。解决方案：在具有多个内置试剂的核酸分析盒中，可以通过使用空气压力的装置中的非接触液体进料来供给试剂溶液; 对于盒体和膜之间的结合，进行通过沉积的直接接合; 对于盒和膜的材料，选择具有优异的沉积相容性，高耐热性，高耐化学性，低吸水性和低蒸汽透过性的材料。由于通过沉积的粘合不需要引入不同种类的材料并在结合中形成极性官能团，所以不必担心在盒的接合部分处的试剂溶液的腐蚀和核酸吸附，并且粘合是成本低于其他直接粘合工艺。

4. 发明专利

JP2010243223A Nucleic acid analyzing device and nucleic acid analyzer 有权
标题翻译：核酸分析装置和核酸分析仪
公开(公告)号：JP2010243223A
公开(公告)日：2010-10-28
申请号：JP2009089671
申请日：2009-04-02
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： OBARA TAKAYUKI , SAITO TOSHIRO , NARAHARA MASATOSHI , ITABASHI NAOSHI , FUJITA TAKESHI , YOSHIDA HIROSHI
IPC分类号： G01N21/64 , C12M1/00
CPC分类号： G01N21/648
摘要： PROBLEM TO BE SOLVED: To detect the fluorescence, which is emitted from fluorescent dye by irradiation with exciting light with a wavelength of about 500 nm, with high precision in a nucleic acid analyzing device.
SOLUTION: In the nucleic acid analyzing device having a metal body producing localized surface plasmon by light irradiation, the material of the metal body consists of metal selected from any of ruthenium, iridium, palladium and rhodium or an alloy of the metals. These metals efficiently produce localized surface plasmon with respect to light with a wavelength of about 500 nm. Further, as the metals have extremely low ionization tendency and are very chemically stable, they can be used in a reaction solution for a long time. The present invention enables fluorescent measurement of nucleic acid stably and with high efficiency using light with the wavelength of about 500 nm.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：通过在核酸分析装置中以高精度照射波长约500nm的激发光来检测从荧光染料发出的荧光。解决方案：在具有通过光照射产生局部表面等离子体的金属体的核酸分析装置中，金属体的材料由选自钌，铱，钯和铑中的任何一种的金属或金属的合金组成。相对于约500nm波长的光，这些金属有效地产生局部表面等离子体激元。此外，由于金属具有极低的电离倾向并且非常化学稳定，所以它们可长时间地用于反应溶液中。本发明能够使用波长为约500nm的光稳定且高效地进行核酸的荧光测定。版权所有（C）2011，JPO＆INPIT

5. 发明专利

JP2008012859A Imprinting device and imprinting method 有权
标题翻译：印刷装置和印刷方法
公开(公告)号：JP2008012859A
公开(公告)日：2008-01-24
申请号：JP2006188383
申请日：2006-07-07
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： TADA YASUHIKO , OGINO MASAHIKO , YOSHIDA HIROSHI , ANDO TAKUJI , KUWABARA KOSUKE
IPC分类号： B29C59/02 , B81C99/00 , G11B5/84 , H01L21/027
CPC分类号： B29C59/022 , B29C37/0003 , B29C2059/023 , B29L2017/005 , B82Y10/00 , B82Y40/00 , G03F7/0002 , G11B5/855
摘要： PROBLEM TO BE SOLVED: To provide an imprinting device which releases a stamper and an object to be transferred from each other without deforming a transferred structure, and also to provide an imprinting method. SOLUTION: The imprinting device A1 is used for transferring a micro uneven pattern formed in the stamper 2 to the object 1 to be transferred through bringing the stamper 2 in contact with the object 1. In this device A1, the end part of at least, either the stamper 2 or the object 1 has a beveling part. A release means is provided which is used for releasing the stamper 2 and the object 1 in contacted with each other through holding the beveling part of at least, either the stamper 2 or the object 1. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译：要解决的问题：提供一种压印装置，其能够释放压模和要彼此转印的物体而不使转印结构变形，并且还提供压印方法。解决方案：压印装置A1用于通过使压模2与对象1接触来将形成在压模2中的微不平坦图案转印到要传送的对象1.在该装置A1中，至少压模2或对象1具有斜切部分。提供了一种释放装置，其用于通过保持压模2或物体1中的至少一个的倾斜部分来释放压模2和物体1彼此接触。版权所有（C）2008， JPO＆INPIT

6. 发明专利

JP2011033539A Biomolecule immobilized substrate and manufacturing method of the same 有权
标题翻译：生物分子固定基板及其制造方法
公开(公告)号：JP2011033539A
公开(公告)日：2011-02-17
申请号：JP2009181743
申请日：2009-08-04
申请人： Hitachi High-Technologies Corp , 株式会社日立ハイテクノロジーズ
发明人： TADA YASUHIKO , YOSHIDA HIROSHI , SAITO TOSHIRO , NARAHARA MASATOSHI , NAKAGAWA HIROAKI
IPC分类号： G01N33/543 , G01N33/53 , G01N33/547 , G01N33/552 , G01N33/553
CPC分类号： G01N33/54353 , A61K2039/625 , G01N33/543 , G01N33/54393
摘要： PROBLEM TO BE SOLVED: To provide a substrate selectively immobilizing biomolecules in a predetermined area the same. SOLUTION: The biomolecule immobilized substrate is equipped with: a substrate having at lease a first surface and a second surface, a hydrocarbon chain, a functional group selectively bindable to the first surface at one end of the hydrocarbon chain; first linker molecules bound to the first surface via the functional group, a reactive group bindable to a hydrocarbon chain of the first linker molecules; second linker molecules bound to the first linker molecules via binding of the reactive group and the hydrocarbon chain; and biomolecules bound via the second linker molecules. COPYRIGHT: (C)2011,JPO&INPIT

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