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1. 发明专利

JPH0694731A MONITORING DEVICE FOR EVAPORATION OF SPECIMEN FOR AUTOMATIC CHEMICAL ANALYZER 失效
公开(公告)号：JPH0694731A
公开(公告)日：1994-04-08
申请号：JP24301992
申请日：1992-09-11
申请人： HITACHI LTD , HITACHI INSTRUMENTS ENG
发明人： YOKOSE TAIZO , OTAKI TOMOMASA , USUI SHINOBU
IPC分类号： G01N35/02 , G01N35/10 , G01N35/06
摘要： PURPOSE:To improve reliability of analysis result by measuring sample amount before starting analysis and at the time of starting, monitoring sample evapora tion and correcting an evaporation amount. CONSTITUTION:A sampling arm 6 of a sample probe 5 integral with a liquid surface sensor mounted at the arm 6 falls according to a pulse signal to a pulse counting motor 8 for vertically driving the am, and the probe 5 senses a liquid surface. After sensing, the arm 6 rises under the control of a microcomputer. In this case, the microcomputer calculates a height from a bottom of a sample cup 1 to the liquid surface, converts it into a liquid amount and obtains a sample amount V1 in a cup 1 before starting the analysis. Similarly, a sample amount V1 at the time of starting the analysis is obtained. After a predetermined amount of the sample is gathered and reagent is added after the liquid surface is sensed, absorbance is measured. In this case, the amount V1 is compared with the amount V2 by an evaporation amount calculator 13 before starting the analysis and at the time of starting, the evaporation amount is calculated as to the sample decided as V1>V2, corrected as prescribed, and an analysis result is obtained.

2. 发明专利

JPH0560769A METHOD FOR SAMPLING MINUTE AMOUNT OF SPECIMEN FOR AUTOMATIC ANALYZER 失效
公开(公告)号：JPH0560769A
公开(公告)日：1993-03-12
申请号：JP22394691
申请日：1991-09-04
申请人： HITACHI LTD , HITACHI INSTRUMENTS ENG
发明人： YOKOSE TAIZO , USUI SHINOBU , OTAKI TOMOMASA
IPC分类号： G01N1/00 , G01N21/31 , G01N31/20 , G01N31/22 , G01N35/10
摘要： PURPOSE:To sample a minute amount of specimen efficiently and highly accurately by detecting the level of a sample-shortage detecting region with a sample probe, which also serves the role of a liquid-level sensor, and controlling the depth of the tip of the probe and the driving of a syringe. CONSTITUTION:A sampling arm 5 is driven 6. A sampling probe 4, which also serves the roles of a liquid level sensor and a sampling nozzle, is brought into contact with the liquid surface of a specimen in a sample cup 10b, and the specimen is sampled. When the amount of the specimen is as minute as about, e.g. 20-30mul, the tip of the probe 4 is inserted down to the bottom of the cup 10b. Therefore, there is no dummy amount of the specimen, which is caused by the difference between the heights of both tips of the sensor and the nozzles, at all. The tip of the probe 4 is inserted beneath the liquid surface by the amount of the level after the tip of the probe 4 comes into contact with the liquid surface based on the level information in a sample-shortage detecting region from the bottom of the cup 10b. Therefore, the specimen is not attached. When the total amount of the specimen becomes lower than the maximum amount of the apparatus, the driving of a specimen sampling syringe 1 is controlled, and the sucking of air is prevented. Therefore, the sampling accuracy can be maintained.

3. 发明专利

JP2000105239A BIOCHEMICAL AUTOMATIC ANALYZER 失效
公开(公告)号：JP2000105239A
公开(公告)日：2000-04-11
申请号：JP27459598
申请日：1998-09-29
申请人： HITACHI LTD , HITACHI INSTRUMENTS ENG
发明人： OTAKI TOMOMASA , SAITO KIYOTAKA , YOKOSE TAIZO , IMAI KYOKO
IPC分类号： G01N33/52 , G01N21/27 , G01N35/00
摘要： PROBLEM TO BE SOLVED: To simply and surely detect abnormality, and to predict a life of a replacing component, by measuring an absorbance using a colored substance after absorbance measurement using pure water to determine that a data trouble exists in any side out of a photometric system and a dispensing system. SOLUTION: Washing for reaction vessels is started, a fixed amount of water are dispensed into one specified vessel and a plurality of reaction vessels, respectively, to measure absorbances, and measured results are determined as a check (1) and a check (2) respectively. The check (1) is compared with the check (2) to judge whether a cause exists in the reaction vessel or a light source based on an allowance value. Pure water is thereafter dispensed after a fixed amount of colored substance are dispenced from a sample probe into the plural reaction vessels (group A) after washing. The fixed amounts of the colored substance and pure water are delivered at the same time into another reaction vessels (group B) with no sample dispensed, using a reagent probe. Absorbance- measured values of the groups A, B are determined as checks (4), (5), and the checks (4), (5) are compared each other to judge whether a cause exists in deterioration of sampling precision or in a reagent pipetting mechanism.

4. 发明专利

JPH05180851A MICRO SPECIMEN SAMPLING METHOD FOR AUTOMATIC ANALYZER 失效
公开(公告)号：JPH05180851A
公开(公告)日：1993-07-23
申请号：JP31889591
申请日：1991-12-03
申请人： HITACHI LTD , HITACHI INSTRUMENTS ENG
发明人： OTAKI TOMOMASA , YOKOSE TAIZO , MIMAKI HIROSHI , SATO TAKESHI
IPC分类号： G01N35/10 , G01N35/00
摘要： PURPOSE:To allow efficient, effective sampling by avoiding test items which are impossible to measure due to shortage of specimens in a sample cup in analyzing multiple items of micro specimens at the same time and eliminating an operating time necessary for retesting. CONSTITUTION:A pulse counting motor 3 to drive up and down a syringe 1 to sample specimens and a plunger 2 which is mounted on the syringe 1, a sample probe 4 as a testee sampling nozzle which is furnished with a liquid level sensor and a sampling arm 5 to give up-and-down and rotational drive thereto are provided. In addition, pulse counting motors 6, 7 to rotate and drive up and down the sampling arm, a drive control circuit 8, a microcomputer 10 to control liquid amount conversion function 9a, a specimen amount automatically judging function 9b and a reduction rate judging function 9c, a sample cup information memory 11a, and a sampling priority memory 11b are also provided.

5. 发明专利

JPH07289286A METHOD FOR MEASURING ACTIVITY OF ENZYME IN AUTOMATIC CHEMICAL ANALYSIS DEVICE 失效
公开(公告)号：JPH07289286A
公开(公告)日：1995-11-07
申请号：JP9104294
申请日：1994-04-28
申请人： HITACHI LTD , HITACHI INSTRUMENTS ENG
发明人： OTAKI TOMOMASA , YOKOSE TAIZO , TSUJIKAWA ATSUKO
IPC分类号： G01N35/02 , C12Q1/00
摘要： PURPOSE:To eliminate the re-examination of a highly active specimen from a serious injury patient, the re-examination having been a problem on an enzyme with a conventional automatic chemical analysis device and by a conventional measuring method, and to shorten a time required for a clinical chemical examination. CONSTITUTION:This biochemical automatic analysis device comprises sample disks 2 having plural sample cups set therein, a sample probe 5 for sampling specimens, reaction containers used also as cuvettes, a spectroscope 9 for measuring the reduction (or increase) in absorbance, a reagent-injecting mechanism 32 for re-injecting a reagent into a reaction solution of reaction saturation state, and a central processing device 21 for performing the control of the whole device and the whole data-processing such as the calculation of the liquid volume correction coefficient of the reagent and the computation of the concentration (enzymatic activity).

6. 发明专利

JPH07159416A AUTOMATIC CHEMICAL ANALYZER 失效
公开(公告)号：JPH07159416A
公开(公告)日：1995-06-23
申请号：JP30250993
申请日：1993-12-02
申请人： HITACHI LTD , HITACHI INSTRUMENTS ENG
发明人： YOKOSE TAIZO , TSUJIKAWA ATSUKO , OTAKI TOMOMASA , SHIRAISHI SO
IPC分类号： G01N35/04 , G01N35/10
摘要： PURPOSE:To provide a highly reliable automatic chemical analyzer which can avoid cross contamination of a reagent probe intrinsic to a reagent pipetting system without lowing function of the analyzer while eliminating the occurrence of undesired results of analysis. CONSTITUTION:This apparatus is made up of a sample disc 2 which allows the mounting of a plurality of sample cups 1 thereon, a sampling mechanism 4 to dispense a sample, reagent pipetting mechanisms 6a and 6b adapted to dispense a plurality of regents, a reaction disc 9 which holds reagent discs 7a and 7b and a plurality of reaction containers 8, an agitation mechanism 10, a reaction container washing mechanism 11, a multi-wavelength photometer 12 and a central processing unit to perform a control of a mechanism system as a whole and a data processing.

7. 发明专利

JP2001228158A AUTOMATIC ANALYZER AND AUTOMATIC ANALYZING METHOD 失效
公开(公告)号：JP2001228158A
公开(公告)日：2001-08-24
申请号：JP2000046776
申请日：2000-02-18
申请人： HITACHI LTD , HITACHI SCIENCE SYSTEMS LTD
发明人： KIKUCHI TAKAHIRO , MIMURA TOMONORI , HATTORI MITSUO , HAYASHI MASAMI , USUI SHINOBU , OTAKI TOMOMASA , SAITO NAOKO
IPC分类号： G01N35/02
摘要： PROBLEM TO BE SOLVED: To provide an automatic analyzer of a type in which a carrying rack having a sample placed thereon is carried and measurement is advaced, and which enables the repeated measurement of the same item from the same sample vessel to be performed many times. SOLUTION: In this device, a new function of evaluation mode is added, so that a sample rack number 303 and a position number 304 can be added to the input information of measurement request in addition to a sample number 302, and the same sample rack number and the same position number can be also inputted to perform the repeated measurement of the same item from the same sample vessel. The same sample ID number 401 can be inputted to the input information of measurement request, so that the repeated measurement of the same item from the same sample vessel can be performed. In the input of measurement request, a plurality of requests for the same measurement item can be requested to one sample. A basic performance measurement such as simultaneous reproducibility or the like is instructed on a screen for displaying a basic performance measurement item.

8. 发明专利

JP2002296284A AUTOMATIC ANALYZER 失效
公开(公告)号：JP2002296284A
公开(公告)日：2002-10-09
申请号：JP2001102783
申请日：2001-04-02
申请人： HITACHI LTD , HITACHI SCIENCE SYSTEMS LTD
发明人： OTAKI TOMOMASA , SAITO KIYOTAKA , KIKUCHI TAKAHIRO , HAYASHI MASAMI , MIMURA TOMONORI
IPC分类号： G01N35/00
摘要： PROBLEM TO BE SOLVED: To reduce a part cost in a consumable part of an automatic analyzer, and a burden, onto an operator, of a working volume other than routine work, and to allow the operator to be devoted entirely to inspection work. SOLUTION: Replacing timing of the comsumable part and a part name are determined by combining accumulated values of electrified times in the analyzer and measuring times therein, a date and hour in the last replacement of the part having a life provided by an interactive mode with the operator on an image plane, and information by visual confirmation of an analyzer condition such as a residual amount of a high tergent liquid, and the presence of clogging or the like in an ion-exchanged water nozzle for cell blank.

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