会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 2. 发明专利
    • Mass spectrometer and mass spectrometry
    • 质谱仪和质谱仪
    • JP2009170238A
    • 2009-07-30
    • JP2008006372
    • 2008-01-16
    • Hitachi Ltd株式会社日立製作所
    • SUGIYAMA MASUYUKIHASHIMOTO YUICHIROHASEGAWA HIDEKITAKADA YASUAKI
    • H01J49/42G01N27/62H01J49/40
    • H01J49/0045
    • PROBLEM TO BE SOLVED: To solve the problem that a conventional MS/MS method cannot compatibly attain throughput and precursor ion mass resolution.
      SOLUTION: This mass spectrometer includes an ion trap for discharging ions in a specified mass range, a collision dissociation part for dissociating the ions discharged from the ion trap, and a mass spectrometric part for performing the mass spectrometry of the ions discharged form the collision dissociation part. It resonantly discharges the ions introduced and accumulated into the iron trap in a mass selective manner. It measures the precursor ions in the conditions that incident energy into the collision dissociation part is low, and acquires a set of the profile of the precursor ions at the mass axis of the ion trap part and the profile thereof at the mass spectrometric part. Then, it measures the precursor ions in the conditions that incident energy into the collision dissociation part is high, and replaces the profile at the mass axis of the mass spectrometric part with the profile of the precursor ions of the obtained two-dimensional mass spectrum at the mass axis of the iron trap part. In this method, m/z of each of the precursor ions and fragment ions can be determined with high mass resolution.
      COPYRIGHT: (C)2009,JPO&INPIT
    • 要解决的问题:为了解决常规MS / MS方法不能兼容地获得通过量和前体离子质量分辨率的问题。 解决方案:该质谱仪包括用于在特定质量范围内排出离子的离子阱,用于解离从离子阱排出的离子的碰撞解离部分和用于进行离子排出形式的质谱的质谱部分 碰撞解离部分。 它以质量选择的方式谐振地放出引入并累积到铁捕集器中的离子。 它在入射到碰撞解离部分的能量较低的条件下测量前体离子,并且在离子阱部分的质量轴和质谱部分的轮廓获取一组前体离子的轮廓。 然后,在入射到碰撞解离部分的能量高的条件下,测量前体离子,并将所得二维质谱的前体离子的轮廓替换在质谱部分的质心轴处的轮廓 铁陷阱部分的质量轴。 在该方法中,可以以高质量分辨率确定每个前体离子和碎片离子的m / z。 版权所有(C)2009,JPO&INPIT
    • 3. 发明专利
    • Analyzer
    • 分析仪
    • JP2009063389A
    • 2009-03-26
    • JP2007230903
    • 2007-09-06
    • Hitachi Ltd株式会社日立製作所
    • HASHIMOTO YUICHIROHASEGAWA HIDEKISUGIYAMA MASUYUKITAKADA YASUAKI
    • G01N27/62H01J49/10
    • H01J49/0036
    • PROBLEM TO BE SOLVED: To provide a method and means for performing accurate quantification by neither reducing measuring throughput nor adding a multicomponent standard compound.
      SOLUTION: In this analyzer having means for ionizing a mixture, which is obtained by adding a specific compound to a measuring sample, to mass-analyze the formed ions and quantifying the concentration of the measuring target compound contained in the measuring sample, a database which stores the signal intensity dependence to the concentration of a certain matrix component with respect to the measuring target compound and the added compound is provided and the concentration of the measuring target compound is corrected from the signal originating from the measuring target compound obtained by the mass analyzing means and the signal originating from the added compound. A multicomponent analyzer using mass analysis of low cost and high throughput as compared with a conventional technique can be realized.
      COPYRIGHT: (C)2009,JPO&INPIT
    • 要解决的问题:提供通过既不降低测量量也不添加多组分标准化合物来进行精确定量的方法和装置。 解决方案:在具有将通过向测量样品中加入特定化合物而获得的混合物离子化的装置中,对形成的离子进行质量分析并量化测量样品中包含的测量目标化合物的浓度的分析仪中, 存储与相对于测定对象化合物和添加的化合物相对于特定的基质成分的浓度的信号强度依赖性的数据库,根据来自测定对象化合物的信号,由测定对象化合物的信号 质量分析装置和来自添加的化合物的信号。 可以实现使用与常规技术相比低成本和高吞吐量的质量分析的多组分分析仪。 版权所有(C)2009,JPO&INPIT
    • 4. 发明专利
    • Ionic mobility analyzer and ionic mobility-separator/mass-spectroscopy composite apparatus
    • 离子移动分析仪和离子移动分离器/质谱复合装置
    • JP2008282542A
    • 2008-11-20
    • JP2007122956
    • 2007-05-08
    • Hitachi Ltd株式会社日立製作所
    • HASHIMOTO YUICHIROHASEGAWA HIDEKISUGIYAMA MASUYUKITAKADA YASUAKI
    • H01J49/40G01N27/62
    • G01N27/622
    • PROBLEM TO BE SOLVED: To provide an ionic mobility separation filter of low cost and high ion transmissivity, capable of allowing ions in a specific ionic mobility range to pass at atmospheric pressure. SOLUTION: The apparatus comprises an ion source, a first drift region in which the direction of a direct current electric field is opposite to the gas low direction, a second drift region in which the direction of applying a direct current electric field is opposite to a gas flow direction different from the gas flow direction in the first drift region, an intermediate region having an electric field to proceed ions between the first and second drift regions, and a detector to detect ions passing through the first and second regions. COPYRIGHT: (C)2009,JPO&INPIT
    • 要解决的问题:提供低成本和高离子透射率的离子迁移率分离过滤器,其能够使特定离子迁移率范围内的离子在大气压下通过。 解决方案:该装置包括离子源,直流电场的方向与气体低方向相反的第一漂移区域,施加直流电场的方向的第二漂移区域为 与不同于第一漂移区域中的气体流动方向的气体流动方向相反的中间区域,具有用于在第一和第二漂移区域之间进行离子的电场的中间区域以及检测通过第一和第二区域的离子的检测器。 版权所有(C)2009,JPO&INPIT
    • 10. 发明专利
    • ION SOURCE
    • JP2000057991A
    • 2000-02-25
    • JP22343099
    • 1999-08-06
    • HITACHI LTD
    • HIRABAYASHI TSUDOIHIRABAYASHI YUKIKOSAKAIRI MINORUTAKADA YASUAKINABESHIMA TAKAYUKIKOIZUMI HIDEAKI
    • H01J49/10G01N27/447G01N27/62G01N30/72H01J49/04
    • PROBLEM TO BE SOLVED: To produce positive or negative ions with high efficiency, by installing an electrode near a spray capillary and by applying an electric field on liquid and by spraying the liquid, in a sonic spray ionization method. SOLUTION: This ion source is equipped with a capillary 2 for spraying liquid into the atmospheric air, and an orifice 3 installed by inserting a part near the head of the capillary 2 and formed so that gas will flow up to the head of the capillary 2 along the circumferential wall surface of the capillary 2. A gas flow velocity near the head of the capillary 2 is about a sound velocity, and a voltage is applied between the liquid in the capillary 2 and the orifice 3 or an electrode installed near the capillary 2. Hereby, the electric potential of the liquid can be set equally to the earth potential, and combination of a solution separation means with a liquid introduction part is easily realized. Also, the polarity of produced ions can be controlled according to the polarity of the voltage applied on the electrode. Besides, multi-charged ions of material having a large mass, such as a protein or the like, or the like can be produced with high efficiency and excellent repeatability.