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1. 发明专利

JP2001091518A AUTOANALYZER 失效
公开(公告)号：JP2001091518A
公开(公告)日：2001-04-06
申请号：JP26496599
申请日：1999-09-20
申请人： HITACHI LTD , HITACHI SCIENCE SYSTEMS LTD
发明人： USUI SHINOBU , SAITO KIYOTAKA , HAYASHI MASAMI , MIMURA TOMONORI
IPC分类号： G01N21/90 , G01N21/15 , G01N21/27 , G01N35/00
摘要： PROBLEM TO BE SOLVED: To provide the deterioration information of a reaction container to an operator with an alarm or the like by measuring the blank value of the reaction container to be made in an analysis for entire wavelength that can be utilized for each reaction container, storing the value along with the measurement data/time in accumulation, preparing a reference value for each reaction container without requiring any measurement of the blank value, and achieving the propriety of the usage of the reaction container, the confirmation of the change in the blank value, and the isolation of the factors of the change in the bland value. SOLUTION: The autoanalyzer is provided with a control part for collecting the blank absorbance (blank value) of a reaction container to be measured when washing the reaction container in an analysis for entire wavelength that can be used by the device, a storage part for accumulating and storing the blank value for each reaction container in time series, an operation part for calculating the amount of change of each reaction container from a plurality of blank values being accumulated and stored according to the regression expression of the blank value and measurement time, and a function for judging the deterioration of the reaction container by comparing the calculated amount of change with the most recent blank value.

2. 发明专利

JP2000105246A AUTOMATIC ANALYZER 失效
公开(公告)号：JP2000105246A
公开(公告)日：2000-04-11
申请号：JP27461198
申请日：1998-09-29
申请人： HITACHI LTD , HITACHI INSTRUMENTS ENG
发明人： HAYASHI MASAMI , HATTORI MITSUO , SAITO KIYOTAKA , MIMAKI HIROSHI
IPC分类号： B65G1/00 , B65G43/00 , G01N35/02 , G01N35/04
摘要： PROBLEM TO BE SOLVED: To quickly analyze a rack mounted with a sample having an analyzing priority by providing a buffer part capable of storing plural racks loop-likely on a conveying line in an automatic analyzer in which the racks mounted with the sample are conveyed on the conveying line to be analyzed. SOLUTION: When a rack buffer part 12 is formed into a circular form, such motion is repeated that a rack 1 is conveyed from an A-line 2 in order, and that it is stored in the order of an R11 part 19 of the buffer part 12 and its R21 part 20 through a B1 line 6. When a specific position R31 part 21 of the buffer part 12 is served as the rack exclusive to the rack having a priority, the R31 part 21 is rotated on an extended line of the B1 line 6 to be prior to the rack 1 conveyed already to the buffer part 12 in the case where the rack 1 having the priority for analysis is conveyed, and the rack 1 having the priority is stored to the buffer part 12. A rack feed switch is allowed to be provided in the vicinity of the buffer part 12 to feed directly the rack 1 having the priority.

3. 发明专利

JP2002296284A AUTOMATIC ANALYZER 失效
公开(公告)号：JP2002296284A
公开(公告)日：2002-10-09
申请号：JP2001102783
申请日：2001-04-02
申请人： HITACHI LTD , HITACHI SCIENCE SYSTEMS LTD
发明人： OTAKI TOMOMASA , SAITO KIYOTAKA , KIKUCHI TAKAHIRO , HAYASHI MASAMI , MIMURA TOMONORI
IPC分类号： G01N35/00
摘要： PROBLEM TO BE SOLVED: To reduce a part cost in a consumable part of an automatic analyzer, and a burden, onto an operator, of a working volume other than routine work, and to allow the operator to be devoted entirely to inspection work. SOLUTION: Replacing timing of the comsumable part and a part name are determined by combining accumulated values of electrified times in the analyzer and measuring times therein, a date and hour in the last replacement of the part having a life provided by an interactive mode with the operator on an image plane, and information by visual confirmation of an analyzer condition such as a residual amount of a high tergent liquid, and the presence of clogging or the like in an ion-exchanged water nozzle for cell blank.

4. 发明专利

JPH11271329A Automatic analyzing device 失效
标题翻译：自动分析装置
公开(公告)号：JPH11271329A
公开(公告)日：1999-10-08
申请号：JP7696998
申请日：1998-03-25
申请人： Hitachi Instr Eng Co Ltd , Hitachi Ltd , 日立計測エンジニアリング株式会社 , 株式会社日立製作所
发明人： KIKUCHI TAKAHIRO , HATTORI MITSUO , HAYASHI MASAMI , MIMURA TOMONORI
IPC分类号： B32B1/08 , G01N35/10
摘要： PROBLEM TO BE SOLVED: To prevent carry-over by using polytetrafluoroethylene (PTFE) for the inner side of a dispensing nozzle. SOLUTION: A nozzle formed of PTFE is constituted of four components of a PTFE tube 36, a nozzle tip 37 formed of conductive material at the tip of the tube 36, an outer cylinder 38 formed of conductive material for mechanically supporting the tube 36 and for transmitting an electric signal of liquid level direction, and a joint 39 for finally connecting to a channel. The conductive nozzle tip 37 at the nozzle tip is in close contact with and connected to the tube 36 and is fixed by the engagement between a male screw thread cut in the nozzle tip 37 and a female screw thread cut in the outer cylinder 38. The PTFE tube 36 is replaced by unfastening these screws.
摘要翻译：要解决的问题：为了防止在分配喷嘴的内侧使用聚四氟乙烯（PTFE）进行携带。解决方案：由PTFE制成的喷嘴由PTFE管36的四个部件构成，在管36的前端由导电材料形成的喷嘴尖端37，由用于机械地支撑管36的导电材料形成的外筒38，发送液位方向的电信号，以及最终连接到通道的接头39。喷嘴尖端处的导电喷嘴尖端37与管36紧密接触并连接到管36，并且通过在喷嘴尖端37中切割的外螺纹螺纹与外筒38中切割的内螺纹螺纹之间的接合来固定。通过松开这些螺钉代替PTFE管36。

5. 发明专利

JPH09211006A AUTOMATIC CHEMICAL ANALYZER 失效
公开(公告)号：JPH09211006A
公开(公告)日：1997-08-15
申请号：JP1636596
申请日：1996-02-01
申请人： HITACHI LTD
发明人： HAYASHI MASAMI , HATTORI MITSUO
IPC分类号： G01N35/02 , G01N35/10
摘要： PROBLEM TO BE SOLVED: To prevent erroneous measurement caused by the washing insufficiency of a reaction container by preventing the contamination of a reaction soln. discharge passage caused by the mutual interference of reaction solns. and the clogging of the passage by the formation of crystals by selecting a proper detergent to perform washing. SOLUTION: A reaction container washing mechanism 3 is constituted of a detergent distribution nozzle 3a for washing a reaction soln. discharge passage, a reaction soln. discharge and reaction container washing soln. distribution nozzle 3b, the washing nozzle 3c of a reaction container, a nozzle 3d draining water in the reaction container and a purified water distribution nozzle 3e for measuring the water plank of the reaction container and the washing of the reaction container 2 is performed. In this case, control is performed by a computer having a program selecting and adding a proper detergent automatically according to the kind of a sucked and discharged reaction soln. and a detergent 7 for washing a reaction soln. discharge passage is distributed to the reaction container 2 by a detergent distribution mechanism 8.

6. 发明专利

JPH09274040A METHOD AND APPARATUS FOR AUTOMATIC IMMUNITY ANALYSIS 失效
公开(公告)号：JPH09274040A
公开(公告)日：1997-10-21
申请号：JP8120496
申请日：1996-04-03
申请人： HITACHI LTD , HITACHI INSTRUMENTS ENG
发明人： SAITO KIYOTAKA , HAYASHI MASAMI , SHICHIJI MASARU
IPC分类号： G01N33/543 , G01N35/02
摘要： PROBLEM TO BE SOLVED: To enhance the reliability of a measured result by a method wherein, according to the compared result of areas in ranges which are designated arbitrarily on the basis of a reaction process absorbence, the existence of a reaction suppression phenomenon due to the excess of an antigen is judged. SOLUTION: A sampling disk 2 is turned, a sample container 1 into which a sample is put is moved to a sampling position, and a sample in a constant is put is sucked by a sampling mechanism 3 so as to be discharged into a reaction container 7. The reaction container 7 is moved to a reagent dispensing position in a next cycle so as to be stopped, and a reagent is added by a reagent disk 4a and a reagent pipetting mechanism 5a. Then, whenever a reaction disk 8 is turned, the reaction container 7 crosses an optical axis, and an absorbance is measured by a photometer 10, a wavelength selector 11 and the like. A CPU 15 compares areas in two ranges which are disignated arbitrarily on the basis of a reaction process absorbance (i.e., computes an area ratio), and the existence of a reaction suppression phenomenon due to the excess of an antigen is judged accordingly. The measured absorbance is contorted into a concentration so as to be output.

7. 发明专利

JP2001228158A AUTOMATIC ANALYZER AND AUTOMATIC ANALYZING METHOD 失效
公开(公告)号：JP2001228158A
公开(公告)日：2001-08-24
申请号：JP2000046776
申请日：2000-02-18
申请人： HITACHI LTD , HITACHI SCIENCE SYSTEMS LTD
发明人： KIKUCHI TAKAHIRO , MIMURA TOMONORI , HATTORI MITSUO , HAYASHI MASAMI , USUI SHINOBU , OTAKI TOMOMASA , SAITO NAOKO
IPC分类号： G01N35/02
摘要： PROBLEM TO BE SOLVED: To provide an automatic analyzer of a type in which a carrying rack having a sample placed thereon is carried and measurement is advaced, and which enables the repeated measurement of the same item from the same sample vessel to be performed many times. SOLUTION: In this device, a new function of evaluation mode is added, so that a sample rack number 303 and a position number 304 can be added to the input information of measurement request in addition to a sample number 302, and the same sample rack number and the same position number can be also inputted to perform the repeated measurement of the same item from the same sample vessel. The same sample ID number 401 can be inputted to the input information of measurement request, so that the repeated measurement of the same item from the same sample vessel can be performed. In the input of measurement request, a plurality of requests for the same measurement item can be requested to one sample. A basic performance measurement such as simultaneous reproducibility or the like is instructed on a screen for displaying a basic performance measurement item.

8. 发明专利

JP2000266761A AUTOMATIC ANALYZER 失效
公开(公告)号：JP2000266761A
公开(公告)日：2000-09-29
申请号：JP7232799
申请日：1999-03-17
申请人： HITACHI LTD , HITACHI SCIENCE SYSTEMS LTD
发明人： KIKUCHI TAKAHIRO , SAITO KIYOTAKA , HAYASHI MASAMI , HATTORI MITSUO , MIMURA TOMONORI
IPC分类号： G01N35/04
摘要： PROBLEM TO BE SOLVED: To improve efficiency of an extraction work of a test body sample. SOLUTION: A rack L where a sample vessel is set is conveyed from a rack makeup part 10 to a rack storing part 40 by a conveyance line 50, and the rack L is returned around back to the rack makeup part 10 side by a circulation line 54. A makeup side rack number reading part 60 reads a rack number of the rack L conveyed by the conveyance line 50, and the read order of the rack L is memorized in a memory 72. A storage side rack number reading part 62 is arranged on the storage side, and reads a rack number of the conveyed rack L. If the rack L has a number to be stored, a control part 70 stores the rack L in the rack storing part 40, or otherwise, the control part 70 returns the rack L around back to the rack makeup side through the circulation line 54.

9. 发明专利

JPS61258172A REAGENT FOR IMMUNOLOGICAL ANALYSIS AND IMMUNOLOGICAL ANALYSIS USING SAID REAGENT 失效
公开(公告)号：JPS61258172A
公开(公告)日：1986-11-15
申请号：JP9898685
申请日：1985-05-10
申请人： HITACHI LTD , HITACHI INSTRUMENTS ENG
发明人： HAYASHI MASAMI , MAKIGUCHI KYOKO , NOMURA YASUSHI
IPC分类号： G01N33/53 , A61K39/00 , G01N33/544
摘要： PURPOSE:To make possible the quantitative determination of the antigen or antibody which is the intended trace component in a sample with high sensitivity in a short analyzing period by incorporating a compd. which emits the time- divided fluorescence as an index into a microcapsule conjugated with the antigen or antibody. CONSTITUTION:An animal membrane, for example, the red blood cells of goat are used as the microcapsule which can conjugate the antigen or antibody. The red blood cells of other animals or animal cells in addition to the red blood cells or even liposome which are the artificial membrane are used by conjugating the antibody or antigen to the membrane. Any material can be used as the microcapsule if the microcapsule can contain the compd. emitting the time-divided fluorescence as the index. The method for conjugating the antigen or antibody to the membrane permits the conjugation of an antigen or antibody by adsorption therewith if the membrane is the animal membrane and permits the conjugation of the antigen or antibody with the membrane by forming, for example, a carboxyl group to the membrane if the membrane is the artificial membrane.

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