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1. 发明专利

JP2012000093A New lactobacillus, and new lactobacillus-containing composition 有权
标题翻译：新的乳酸杆菌和新的含有乳酸杆菌的组合物
公开(公告)号：JP2012000093A
公开(公告)日：2012-01-05
申请号：JP2010141049
申请日：2010-06-21
申请人： Rakuno Gakuen , 学校法人酪農学園
发明人： HAGIWARA KATSURO , ISHII TOMOMI , IWANO HIDETOMO , MORI YUUKO
IPC分类号： C12N1/20 , A23K1/16 , A23L1/30 , A61K35/74 , A61P31/04 , A61P37/06
摘要： PROBLEM TO BE SOLVED: To provide a new lactobacillus in spite of being inexpensive and capable of being proliferated easily, exhibiting physiological activities equal to or higher than those of useful lactobacilluses strains known conventionally, and newly provide medicines, foods and feeds, containing the viable cells of the same.SOLUTION: The medicines, feeds and foods exhibiting immunity disease-improving effects are provided by using the viable cells of a new lactobacillus, Lactobacillus plantarum RGU-Lp1 strain separated from fermented milk as an active ingredient. Also the medicines, feeds and foods exhibiting infectious disease-preventing and treating effects which are different effects from those in the case of using the viable cells as the active ingredient are provided by using the filtrate of a culture supernatant of the above as the active ingredient.
摘要翻译：要解决的问题：为了提供新的乳杆菌，尽管价格便宜并且能够容易地增殖，表现出等于或高于常规已知的有用的乳酸杆菌菌株的生理活性，并且新提供药物，食品和饲料，含有相同的活细胞。解决方案：通过使用从发酵乳中分离的新型乳杆菌，植物乳杆菌RGU-Lp1菌株的活细胞作为活性成分，提供具有免疫疾病改善效果的药物，饲料和食品。通过使用上述培养上清液的滤液作为活性成分，提供与使用活细胞作为活性成分的情况不同的效果的具有感染性疾病预防和治疗效果的药物，饲料和食品。版权所有（C）2012，JPO＆INPIT

2. 发明专利

JP2011050363A Method for producing neokestose 有权
标题翻译：生产骨菌的方法
公开(公告)号：JP2011050363A
公开(公告)日：2011-03-17
申请号：JP2009205081
申请日：2009-09-04
申请人： Nippon Beet Sugar Mfg Co Ltd , Rakuno Gakuen , 学校法人酪農学園 , 日本甜菜製糖株式会社
发明人： UENO TAKASHI , ONODERA SHUICHI , SHIOMI TOKUO , ABE MASAMI , NAKAGAWA AYANO , KIKUCHI HIROTO
IPC分类号： C12P19/14 , C12N15/09
摘要： PROBLEM TO BE SOLVED: To provide a method for efficiently isolate neokestose and produce high-purity neokestose by using a fructan-containing composition (a composition containing neofructooligosaccharide and fructooligosaccharide in a mixed state) as a raw material.
SOLUTION: Neokestose having high purity is produced in high efficiency by treating a fructan-containing composition with a fructan hydrolase having a specific activity (1-FEH (fructan 1-exohydrolase), etc.) to selectively decompose fructan other than neokestose while leaving only glucose, fructose, sucrose and neokestose, and subjecting the enzyme-treated liquid to chromatographic separation.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供一种通过使用含有果聚糖的组合物（以混合状态含有低聚果寡糖和低聚果糖的组合物）作为原料，有效地分离出来的新闻组合物并产生高纯度组合物的方法。解决方案：通过用具有比活性的果聚糖水解酶（1-FEH（果聚糖1-脱水水解酶）等）处理含有果聚糖的组合物，以高效的方式产生高纯度的Neokestose，以选择性地分解除了重氮化物之外的果聚糖同时只留下葡萄糖，果糖，蔗糖和烟草，并对酶处理液进行色谱分离。版权所有（C）2011，JPO＆INPIT

3. 发明专利

JP2007024612A Comet assay analysis method, comet assay image analyzer, comet assay analyzer 有权
标题翻译：彗星测试分析方法，彗星测试分析仪，彗星测试分析仪
公开(公告)号：JP2007024612A
公开(公告)日：2007-02-01
申请号：JP2005205181
申请日：2005-07-14
申请人： Hokkaido , Matsushita Ecology Systems Co Ltd , Rakuno Gakuen , 北海道 , 学校法人酪農学園 , 松下エコシステムズ株式会社
发明人： TASHIRO YOSHIKAZU , SHIMAKITA HIROTO , ENDO DAIJI , TAKAHASHI HIROYUKI , HONMA TOSHINORI
IPC分类号： G01N27/447 , C12M1/00 , C12Q1/68
摘要： PROBLEM TO BE SOLVED: To provide a method for performing more accurate comet assay evaluation, by automatically and rapidly calculating respective evaluation indices on a comet assay from a photograph image of a sample, as to a comet assay analysis method. SOLUTION: A comet image 1 comprises a head image 2 and a tail image 3. In this method, a circumscribing rectangle 4 that circumscribes the comet image 1 is found. If the ratio between the area of the comet image 1 and the area of the circumscribing rectangle 4 falls within a prescribed range, the comet image 1 is determined as being of one cell. A comet image, in which a plurality of cells overlap with each other and a comet image other than that of one cell due to fluorescence noise can be excluded, and determination can be made simply and automatically, by using commercially available software, and rapid comet assay evaluation can be made. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：为了提供一种用于进行更准确的彗星测定评价的方法，通过从彗星测定分析方法自动且快速地计算来自样品的照片图像的彗星测定的各个评价指标。解决方案：彗星图像1包括头部图像2和尾部图像3.在该方法中，找到外接彗星图像1的外接矩形4。如果彗星图像1的面积与外接矩形4的面积之间的比率落在规定范围内，则将彗星图像1确定为一个单元。可以排除其中多个单元彼此重叠的彗星图像和由于荧光噪声导致的一个单元的彗星图像，并且可以通过使用市售软件和快速彗星进行简单和自动的确定可以进行测定评估。版权所有（C）2007，JPO＆INPIT

4. 发明专利

JP2014082953A Cancer detection method, cancer detection kit, method for screening for therapeutic agent for cancer, and therapeutic agent for cancer 审中-公开
标题翻译：癌症检测方法，癌症检测套件，用于癌症治疗剂的筛选方法和癌症治疗剂
公开(公告)号：JP2014082953A
公开(公告)日：2014-05-12
申请号：JP2012232014
申请日：2012-10-19
申请人： Rakuno Gakuen , 学校法人酪農学園 , Nihon Dobutsu Tokushu Shindan Ltd , 日本動物特殊診断株式会社
发明人： IWANO HIDETOMO , UCHIDE TAKESHI , KADOSAWA TSUYOSHI
IPC分类号： C12N15/09 , A61K31/7105 , A61K31/713 , A61K48/00 , A61P35/00 , A61P43/00 , C12N15/113 , C12Q1/02 , C12Q1/04 , C12Q1/68
摘要： PROBLEM TO BE SOLVED: To provide a highly accurate cancer detection method, a highly accurate cancer detection kit, an efficient method for screening for a therapeutic agent for cancer, and an effective therapeutic agent for cancer.SOLUTION: A biomarker for cancer uses a miRNA expression level as an index. A diagnostic marker for hemangiosarcoma uses a miRNA expression level as an index. A cancer detection method detects a cancer of a mammal using, as an index, increases in the expression level of one or more miRNAs selected from the group consisting of miRNAs having a specific base sequence in a sample.
摘要翻译：要解决的问题：提供高精度的癌症检测方法，高精度的癌症检测试剂盒，用于癌症治疗剂的筛选的有效方法和癌症的有效治疗剂。解决方案：癌症的生物标志物使用miRNA 表达级别作为索引。血管肉瘤诊断标志物以miRNA表达水平为指标。作为指标，使用选自由样品中具有特定碱基序列的miRNA组成的组中的一种或多种miRNA的表达水平增加，癌症检测方法检测哺乳动物的癌症。

5. 发明专利

JP2011120556A COMPREHENSIVE METHOD FOR DETECTING FIVE KINDS OF VIRUSES OF HIV, HCV, HBV, PvB19 AND WNV HAVING PLURALITY OF GENOTYPES, PRIMER SET FOR VIRUS DETECTION, MICROARRAY AND KIT FOR VIRUS DETECTION 审中-公开
标题翻译：用于检测HIV，HCV，HBV，PvB19和WNV的病毒的多种病毒的综合方法，用于病毒检测的初步设置，用于病毒检测的微阵列和试剂盒
公开(公告)号：JP2011120556A
公开(公告)日：2011-06-23
申请号：JP2009283366
申请日：2009-12-14
申请人： National Institute Of Infectious Diseases , Nippon Paakaaraijingu Hiroshima Kojo:Kk , Rakuno Gakuen , 国立感染症研究所長 , 学校法人酪農学園 , 株式会社日本パーカーライジング広島工場
发明人： NAKAJIMA TATSUO , HAMAGUCHI ISAO , TAKIZAWA KAZUYA , MIZUTANI TETSUYA , ENDO DAIJI
IPC分类号： C12N15/09 , C12M1/00 , C12Q1/68
CPC分类号： C12Q1/701 , C12Q1/6837 , G01N2333/015 , G01N2333/02 , G01N2333/16 , G01N2333/183 , G01N2333/186
摘要： PROBLEM TO BE SOLVED: To provide a comprehensive method for detecting kinds of viruses of HIV, HCV, HBV, PvB19 and WNV having a plurality of genotypes in high specificity and sensitivity, a primer set for virus detection, a microarray and a kit for virus detection. SOLUTION: HIV, HCV, HBV, PvB19 and WNV genes having a plurality of genotypes are amplified using a type-specific primer by PCR and a PCR amplified product is hybridized with a DNA microarray and detected. Five kinds of viruses of HIV, HCV, HBV, PvB19 and WNV having a plurality of genotypes are quickly and simply detected in high specificity and sensitivity by using a primer set for viruses detection and a probe set. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：为了提供具有高特异性和灵敏度的多种基因型的HIV，HCV，HBV，PvB19和WNV的病毒种类的综合方法，用于病毒检测的引物组，微阵列和病毒检测工具包解决方案：使用特异性引物通过PCR扩增具有多个基因型的HIV，HCV，HBV，PvB19和WNV基因，并将PCR扩增产物与DNA微阵列杂交并检测。通过使用用于病毒检测的引物组和探针组，以高特异性和灵敏度快速且简单地检测出具有多种基因型的HIV，HCV，HBV，PvB19和WNV的五种病毒。版权所有（C）2011，JPO＆INPIT

6. 发明专利

JP2009044961A Quality improvement of fish paste product, using odor suppressing bacterium 审中-公开
标题翻译：使用气味抑制细菌的鱼油产品的质量改进
公开(公告)号：JP2009044961A
公开(公告)日：2009-03-05
申请号：JP2007210821
申请日：2007-08-13
申请人： Rakuno Gakuen , Univ Of Tokyo , 国立大学法人東京大学 , 学校法人酪農学園
发明人： WATABE SHIYUUGO , YAMAMOTO TSUNEJI , FUKAMI KATSUYA , FUNATSU YASUJI
IPC分类号： A23L17/00
摘要： PROBLEM TO BE SOLVED: To provide a fish paste product having deodorized fish odor, and to provide a new method for producing the fish paste product. SOLUTION: This method for producing the fish paste product includes adding to a fish meat mince, Staphylococcus bacteria which have an ability of decreasing fish odor when producing the fish paste product from a fish meat mince. COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供具有除臭鱼油气味的鱼浆制品，并提供生产鱼酱产品的新方法。解决方案：用于生产鱼酱产品的方法包括向鱼肉碎片中加入当从鱼肉碎片生产鱼酱产品时具有降低鱼类气味的能力的葡萄球菌。版权所有（C）2009，JPO＆INPIT

7. 发明专利

JP2007193705A Database construction system using probe car data 审中-公开
标题翻译：使用探测车数据的数据库结构系统
公开(公告)号：JP2007193705A
公开(公告)日：2007-08-02
申请号：JP2006013152
申请日：2006-01-20
申请人： Civil Engineering Research Institute Of Hokkaido , Rakuno Gakuen , Union Data System Kk , ユニオンデーターシステム株式会社 , 学校法人酪農学園 , 独立行政法人北海道開発土木研究所
发明人： ASANO MOTOKI , TAKAHASHI NAOHITO , MUNEHIRO KAZUNORI , MITANI MITSUTERU , KINOSHITA DAIZO , NOTO MICHIO , SAKUMA YASUTAKA
IPC分类号： G08G1/01
摘要： PROBLEM TO BE SOLVED: To provide a system for constructing a basic database, which can be used immediately for various analyses by linking positional data, based on probe car data to a road section.
SOLUTION: The database construction system comprises a positional data acquisition means; a storage means for previously storing the road point coordinate data, indicating the position of a road point set on a road and road section identification data for inherently identifying a road section set between two road points; a processing means for deciding which road section includes the positional data, by comparing the positional data with the road point coordinate data and then linking the road section to corresponding road section identification data; and a means for registering the road section in a database, together with the linked road section identification data.
COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于构建基本数据库的系统，其可以基于探测车辆数据到路段将位置数据链接到各种分析中。解决方案：数据库构造系统包括位置数据获取装置; 用于预先存储道路点坐标数据的存储装置，用于指示设置在道路上的道路点的位置和用于固有地识别在两个道路点之间设置的道路段的道路区段识别数据; 一种处理装置，用于通过将位置数据与路点坐标数据进行比较，然后将道路部分与相应的路段识别数据相连，来决定哪个路段包括位置数据; 以及用于将数据库中的路段注册到连接的路段识别数据的装置。版权所有（C）2007，JPO＆INPIT

8. 发明专利

JP2007174926A Feed additive for eliminating mycotoxin 有权
标题翻译：用于消除MYCOTOXIN的饲料添加剂
公开(公告)号：JP2007174926A
公开(公告)日：2007-07-12
申请号：JP2005374675
申请日：2005-12-27
申请人： Coral International Kk , Rakuno Gakuen , コーラルインターナショナル株式会社 , 学校法人酪農学園
发明人： KOIWA MASATERU , YAMAKAWA CHIYOUGEN , OSHIRO AYAKO
IPC分类号： A23K1/175 , A23K1/18
摘要： PROBLEM TO BE SOLVED: To provide a feed additive for eliminating mycotoxin effective for elimination of mycotoxin; to provide a method for reducing an amount of the mycotoxin falling in milk taken from milk cows through using the additive; and to provide a method for producing milk comprising using the additive or using the method. SOLUTION: The feed additive for eliminating mycotoxin consists mainly of fossil coral. The fossil coral is obtained by heating reef-building coral, and pulverizing the heated reef-building coral to activate the coral. The method for producing milk comprises supplying the additive to milk cows. The method for reducing an amount of mycotoxin falling in milk taken from milk cows comprises giving the milk cows the feed to which the fossil coral obtained by heating reef-building coral and pulverizing the heated coral to activate the coral is added. The method for producing milk comprises the method for reducing an amount of mycotoxin. COPYRIGHT: (C)2007,JPO&INPIT
摘要翻译：要解决的问题：提供一种用于消除有效去除真菌毒素的真菌毒素的饲料添加剂; 提供通过使用添加剂减少从奶牛中吸取的乳中的霉菌毒素的量减少的方法; 并提供使用该添加剂或使用该方法的生产牛奶的方法。
解决方案：用于消除霉菌毒素的饲料添加剂主要由化石珊瑚组成。化石珊瑚是通过加热珊瑚礁珊瑚，并加热珊瑚礁来激活珊瑚礁而得到的。生产牛奶的方法包括向奶牛提供添加剂。用于减少从奶牛中取出的牛奶中的霉菌毒素的量的方法包括给奶牛喂食通过加热珊瑚礁珊瑚获得的化石珊瑚并粉碎加热的珊瑚以激活珊瑚的饲料。生产牛奶的方法包括减少真菌毒素的量的方法。版权所有（C）2007，JPO＆INPIT

9. 发明专利

JP2013027359A Method for purifying raffinose 有权
标题翻译：净化方法
公开(公告)号：JP2013027359A
公开(公告)日：2013-02-07
申请号：JP2011166064
申请日：2011-07-28
申请人： Rakuno Gakuen , 学校法人酪農学園 , Nippon Beet Sugar Mfg Co Ltd , 日本甜菜製糖株式会社
发明人： OMORI TOSHIMA , UENO TAKASHI , KIKUCHI MASANORI , ONODERA SHUICHI , SHIOMI TOKUO , HORIUCHI KENICHI , KIKUCHI HIROTO
IPC分类号： C12P19/00 , C12N1/20 , C12N9/26 , C12N15/09 , C13K13/00
CPC分类号： Y02P20/52
摘要： PROBLEM TO BE SOLVED: To provide a method for separating and purifying raffinose of tri-saccharide by selectively removing kestoses of the tri-saccharide from a raffinose-containing liquid, such as sugar a beet production process liquid, in which the raffinose and the kestoses are mixed.SOLUTION: Enzyme treatment is performed by using β-fructofuranosidase derived from Bifidobacterium to selectively decompose the kestoses in the raffinose-containing liquid in which the raffinose and the kestoses being the tri-saccharide are mixed. Thus, the raffinose is simply and efficiently purified.

10. 发明专利

JP2011178653A Method for producing phosphate fertilizer, phosphate fertilizer, carbide of dead livestock 审中-公开
标题翻译：生产磷酸盐肥料，磷酸盐肥料，死亡胆固醇的方法
公开(公告)号：JP2011178653A
公开(公告)日：2011-09-15
申请号：JP2011011954
申请日：2011-01-24
申请人： Rakuno Gakuen , Ss Kenkyusho:Kk , 学校法人酪農学園 , 株式会社S・S研究所
发明人： SHIMIZU TAKAYASU , MATSUNAKA TERUO
IPC分类号： C05F1/00 , B09B3/00
CPC分类号： C05B17/00 , C05D9/00 , C05F1/00 , Y02A40/201 , Y02P20/145
摘要： PROBLEM TO BE SOLVED: To provide a new application of dead livestock carbide which has heretofore had no special use and hence has had to be simply disposed of. SOLUTION: It has been found that a dead livestock carbide exhibits an excellent manuring effect as a phosphate fertilizer. The production of a phosphate fertilizer comprises the step of carbonizing dead livestock. In the production of a phosphate fertilizer, it is desirable that the treatment atmosphere is adjusted to an oxygen-free atmosphere before the carbonization of dead livestock. Further, in the production of a phosphate fertilizer, is desirable that the treatment atmosphere is adjusted to a nitrogen atmosphere before the carbonization of livestock. Thus, it becomes possible to effectively utilize dead livestock as a phosphate fertilizer when it is converted into a carbide. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供迄今为止没有特殊用途的死畜用碳化物的新应用，因此不得不简单地处理。解决方案：已经发现，死亡的家畜碳酸钙作为磷肥表现出优异的施肥效果。磷肥的生产包括将死亡牲畜碳化的步骤。在磷肥的生产中，希望在死亡的家畜碳化之前将处理气氛调节至无氧气氛。此外，在磷酸肥料的制造中，希望在家畜碳化之前将处理气氛调节至氮气氛围。因此，当转化为碳化物时，可以有效地利用死畜作为磷肥。版权所有（C）2011，JPO＆INPIT

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