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101. 发明专利

JP4846246B2 Cladribine local vascular delivery of in combination with rapamycin to prevent restenosis following vascular injury 有权
公开(公告)号：JP4846246B2
公开(公告)日：2011-12-28
申请号：JP2005040910
申请日：2005-02-17
申请人：コーディス・コーポレイションCordis Corporation
发明人：ジョナソン・ゼット・ザオ , トム・ジェイ・パリー , ロバート・ファロティコ
IPC分类号： A61B17/00 , A61L31/00 , A61B17/11 , A61B17/12 , A61F2/06 , A61F2/82 , A61F2/84 , A61K31/436 , A61K31/7076 , A61L17/00 , A61L31/10 , A61L31/16 , A61L33/00 , A61L33/10 , A61P7/02 , A61P9/10
CPC分类号： A61L31/16 , A61L31/10 , A61L2300/416 , A61L2300/45 , A61L2420/08 , C08L33/02 , C08L27/12
摘要： Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.

102. 发明专利

JP2011240046A Tissue fixing implement and fixing system 审中-公开
标题翻译：组织固定和固定系统
公开(公告)号：JP2011240046A
公开(公告)日：2011-12-01
申请号：JP2010116636
申请日：2010-05-20
申请人： Olympus Corp , オリンパス株式会社
发明人： FUJISAKI TAKESHI
IPC分类号： A61B17/08 , A61B17/11
摘要： PROBLEM TO BE SOLVED: To provide a tissue fixing implement which has both the puncturing function and the fixing function and can join and fix tissue by simple measures.SOLUTION: The tissue fixing implement is constituted as follows. That is, the tissue fixing implement includes a needle member 13 which is equipped with a puncture element 13a for puncturing the tissue and a fixing element 13b which penetrates into the tissue through a hole formed in the tissue by puncture and then comes into pressure contact with the tissue, and a deformation restricting member 17, maintained in a first form, wherein a projected area of the needle member 13 on a tissue surface becomes minimum at the time of puncture, the projected area of the needle member 13 being enlarged gradually, linked to the depth of its penetration into the tissue, maintained in a second form wherein the projected area of the needle member 13 becomes maximum, and is brought into the pressure contact with the tissue on the occasion when the penetration into the tissue is completed.
摘要翻译：要解决的问题：提供一种具有穿刺功能和定影功能的组织固定工具，并且可以通过简单的措施来接合和固定组织。解决方案：组织固定工具如下构成。也就是说，组织固定工具包括：针构件13，其配备有用于刺穿组织的穿刺元件13a;以及固定元件13b，其通过穿刺形成在组织中的孔穿入组织，然后与组织和变形限制构件17保持在第一形式，其中组织表面上的针构件13的突出面积在穿刺时变得最小，针构件13的投影面积逐渐扩大，连接保持其穿入组织的深度，保持为第二形式，其中针构件13的投影面积变得最大，并且在渗透到组织中的情况下与组织进行压力接触。版权所有（C）2012，JPO＆INPIT

103. 发明专利

JP4827838B2 Monofilament, hernia surgery mesh, and a method of manufacturing the same that this flexibility and biocompatibility using was improved 有权
公开(公告)号：JP4827838B2
公开(公告)日：2011-11-30
申请号：JP2007514933
申请日：2005-12-22
申请人：サムヤンコーポレーション
发明人：キム，ジュン−ベ , ヨ，グー−ドン , リー，ジェ−ホン
IPC分类号： D01F8/04 , A61B17/11 , A61L17/00 , A61L31/00 , D03D1/00 , D03D9/00 , D03D15/00 , D03D15/02
CPC分类号： A61F2/0063 , A61F2002/0068 , A61F2250/0031 , A61L31/041 , A61L31/148 , B29C47/0014 , B29C47/0057 , B29C47/30 , B29C47/92 , B29C2947/92695 , B29K2023/12 , B29K2067/04 , B29K2995/0037 , B29L2028/00 , B29L2031/7546 , D01D5/08 , D01D5/088 , D01D5/0885 , D01D5/12 , D01D5/16 , D01D5/30 , D01D5/32 , D01D10/00 , D01D10/02 , D02G3/448 , D02J1/22 , D02J1/228 , D02J1/229 , D03D7/00 , D04B1/22 , D04B21/12 , C08L67/04
摘要： The present invention relates to a monofilament with a segmented pie structure formed by conjugated spinning of degradable polymers and non-degradable polymers, a hernia mesh having improved flexibility and biocompatibility, and a preparation method thereof. More specifically, the hernia mesh of the present invention having improved flexibility and biocompatibility is prepared using the monofilament obtained by conjugated spinning of degradable polymers and non-degradable polymers into a segmented pie form, to control it to be gradually degraded in the body, whereby the stiffness of the early stage is removed, and thereby the foreign body sensation is also removed.

104. 发明专利

JP2011527607A Independent medical applicator and methods of use thereof for multi-component formulation 审中-公开
公开(公告)号：JP2011527607A
公开(公告)日：2011-11-04
申请号：JP2011517560
申请日：2009-07-08
申请人：ハイパーブランチメディカルテクノロジー, インコーポレイテッド
发明人：ロイアール．ビー．アットライド， , ジェフリージー．クラーク， , ロバートエム．コロナ， , キースアール．ダレッシオ， , ウェイガイチン， , トッドジェイ．テイラー， , トーマスマツサイティス， , クリストファーアール．ヤーンカー，
IPC分类号： A61B17/11 , A61B17/00 , A61L24/00 , A61L26/00 , A61L31/00
CPC分类号： A61M35/003 , A61B17/00491 , A61B2017/00398 , A61B2017/00495 , A61B2017/00544 , A61B2090/0807 , A61M31/00 , A61M37/00
摘要：本発明のいくつかの態様は、複数の成分処方を分離した材料受容器中に収容でき、次いで使用時に使用者が何も組み立てることなく容易に再構成することのできるアプリケータ、およびその使用方法に関する。本発明の装置は、制限なしに、硬膜、ヘルニア修復における腹部組織、脊椎近くの組織、肺組織、腸組織、および任意の内臓組織にハイドロゲル処方を適用するのに用いることができる。本発明の装置は、処置すべき表面に液体処方のスプレイまたは流れを適用するように構成することができる。本発明の装置は、内視鏡または腹腔鏡を通して処方を送達するように構成することができる。

105. 发明专利

JP4781681B2 Local vascular distribution of mycophenolic acid in combination with rapamycin to prevent restenosis following vascular injury 有权
公开(公告)号：JP4781681B2
公开(公告)日：2011-09-28
申请号：JP2005011779
申请日：2005-01-19
申请人：コーディス・コーポレイションCordis Corporation
发明人：ジョナサン・ゼット・ザオ , トム・ジェイ・パリー , ロバート・ファロティコ
IPC分类号： A61B17/00 , A61F2/84 , A61B17/11 , A61B17/115 , A61F2/06 , A61F2/82 , A61K31/343 , A61K31/436 , A61L31/00 , A61L31/10 , A61L31/16 , A61P7/02 , A61P9/10 , A61P9/14 , A61P41/00 , A61P43/00
CPC分类号： A61L31/10 , A61L31/16 , A61L2300/21 , A61L2300/416 , A61L2420/08 , C08L27/16 , C08L27/20
摘要： Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. Also, the devices may be modified to promote endothelialization. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned. In addition, the devices utilized to deliver the implantable medical devices may be modified to reduce the potential for damaging the implantable medical device during deployment. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.

106. 发明专利

JP2011183180A Compression anastomosis device and method 审中-公开
标题翻译：压缩分析装置和方法
公开(公告)号：JP2011183180A
公开(公告)日：2011-09-22
申请号：JP2011113736
申请日：2011-05-20
申请人： Tyco Healthcare Group Lp , タイコヘルスケアグループエルピー
发明人： VIOLA FRANK
IPC分类号： A61B17/11
CPC分类号： A61B17/11 , A61B17/1114 , A61B2017/1103 , A61B2017/1107 , A61B2017/1117 , A61B2017/1121 , A61B2017/1132
摘要： PROBLEM TO BE SOLVED: To provide an improved anastomotic device which is simple to use, which meets the requirements of anastomotic surgery, and which is safe, and relatively inexpensive. SOLUTION: The anastomotic device 100 for use in the joining of a first tubular structure 200 and a second tubular structure 300 is provided. The anastomotic device 100 includes a cylindrical sleeve 110 configured and dimensioned for placement at least partially within the first tubular structure 200, the cylindrical sleeve defining a bore 114 therethrough; an inverting member 120 configured and dimensioned for placement at least partially within the second tubular structure 300, the inverting member defining a bore 124 therethrough; and a constricting member 130 selectively positionable on the inverting member 120 and movable around the cylindrical sleeve 110 when the cylindrical sleeve 110 is at least partially positioned within the bore 124 of the inverting member 120. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供一种改进的吻合装置，其易于使用，其满足吻合手术的要求，并且是安全的并且相对便宜。解决方案：提供用于连接第一管状结构200和第二管状结构300的吻合装置100。吻合装置100包括圆柱形套筒110，其被构造和尺寸设计成用于至少部分地放置在第一管状结构200内，圆柱形套筒限定穿过其中的孔114; 构造和尺寸设计用于至少部分地放置在第二管状结构300内的翻转部件120，翻转部件限定穿过其中的孔124; 以及收缩构件130，其可选地定位在翻转构件120上并且当圆柱形套筒110至少部分地定位在翻转构件120的孔124内时可围绕圆筒形套筒110移动。版权所有：（C）2011，JPO和INPIT

107. 发明专利

JP2011183035A Surgical instrument 审中-公开
标题翻译：手术器械
公开(公告)号：JP2011183035A
公开(公告)日：2011-09-22
申请号：JP2010052999
申请日：2010-03-10
申请人： Jms Co Ltd , 株式会社ジェイ・エム・エス
发明人： UENO TOMIO , SUZUKI KOJI , MIYAHARA HIDEYASU
IPC分类号： A61B17/04 , A61B17/11 , A61B17/30
摘要： PROBLEM TO BE SOLVED: To provide a variety of improvements for conventional surgical instruments assisting anastomosis. SOLUTION: The surgical instrument includes a pair of leg portions 112 and 114 connected at the base end side 110, and elastically deformable in the direction of approaching each other and the direction of separating from each other, a pair of tilting portions 116 and 118 tilting from the tips of the pair of the leg portions 112 and 114 and extending forward, a pair of tip portions 120 and 122 extending from the tips of the pair of the tilting portions 116 and 118 practically in parallel with the longitudinal directions of the pair of the leg portions 112 and 114, and flexible members 124 interconnecting the pair of the tip portions 120 and 122 with each other. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：为辅助吻合术的常规手术器械提供各种改进。解决方案：手术器械包括一对腿部112和114，其连接在基端侧110处，并且可以在彼此靠近的方向和彼此分离的方向上弹性变形，一对倾斜部116 并且118从一对腿部112和114的尖端倾斜并向前延伸，一对尖端部分120和122从一对倾斜部分116和118的顶端延伸实际上与纵向方向平行一对腿部112和114以及将一对尖端部分120和122彼此互连的柔性构件124。版权所有（C）2011，JPO＆INPIT

108. 发明专利

JP4767292B2 Devices for use in closing the septal defect 有权
公开(公告)号：JP4767292B2
公开(公告)日：2011-09-07
申请号：JP2008178318
申请日：2008-07-08
申请人：セントジュードメディカルエーティージー, インコーポレイテッド
发明人：ジャーメイン，ジョンピーエスティー． , トッドエイ．バーグ， , アレックスエイ．ピーターソン， , マークディー．ワールバーグ，
IPC分类号： A61F2/02 , A61B17/00 , A61B17/064 , A61B17/08 , A61B17/11 , A61B17/12 , A61B17/34 , A61F2/06
CPC分类号： A61B17/3468 , A61B17/0057 , A61B17/064 , A61B17/0643 , A61B17/08 , A61B17/11 , A61B17/3415 , A61B2017/00575 , A61B2017/00659 , A61B2017/0641 , A61F2/064
摘要： A medical graft connector or plug is made, for example, by cutting end portions of a tube of highly elastic material axially at numerous locations spaced circumferentially around the tube to produce a plurality of fingers which extend axially from each end of an uncut medial portion of the tube. The fingers are deflected radially outwardly from the medial portion and set in that condition. For a graft connector, the medial portion is coaxially connected to an end portion of a tubular graft. The connector is then installed through an aperture in the side wall of a patient's tubular body conduit, for example, by using a delivery tube in which the fingers are elastically deflected back to approximately their initial positions. When the delivery conduit is withdrawn from the connector, the fingers spring out to engage the inner and outer surfaces of the body conduit wall. For a plug, the medial portion is occluded and then the structure is installed through the aperture to be plugged in a manner similar to installation of the connector.

109. 发明专利

JP2011156377A Vessel coupling device 有权
标题翻译：船舶联轴器
公开(公告)号：JP2011156377A
公开(公告)日：2011-08-18
申请号：JP2011085115
申请日：2011-04-07
申请人： Cordis Corp , コーディス・コーポレイションCordis Corporation
发明人： BONSIGNORE CRAIG
IPC分类号： A61B17/00 , A61B17/11 , A61F2/06 , A61M25/01
CPC分类号： A61F2/064
摘要： PROBLEM TO BE SOLVED: To provide a device for coupling two vessels seamlessly. SOLUTION: The device includes: a main vessel 10; a bypass vessel 80; a coupling graft 70 disposed within the main vessel end and the bypass vessel end; a main vessel internal stent-anchor 116 and a bypass vessel internal stent-anchor 115 configured to exert an outward force to seal each vessel with the coupling graft; and an external anchor 142 to seal the main vessel end and the bypass vessel end around the coupling graft. The main vessel and the bypass vessel are held in fluid communication via the coupling graft. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供一种无缝连接两个容器的装置。解决方案：该装置包括：主容器10; 旁路容器80; 设置在主容器端和旁路容器端内的联接移植物70; 主容器内部支架锚定件116和旁路容器内部支架锚定件115，其构造成施加向外的力以用联接移植物密封每个容器; 以及外部锚固件142，以密封联接移植物周围的主容器端部和旁路容器端部。主容器和旁路容器通过联接移植物保持流体连通。版权所有（C）2011，JPO＆INPIT

110. 发明专利

JP2011136180A Medical device and method 审中-公开
标题翻译：医疗器械及方法
公开(公告)号：JP2011136180A
公开(公告)日：2011-07-14
申请号：JP2011018823
申请日：2011-01-31
申请人： Genesis Technologies Llc , ジェネシス・テクノロジーズ・エルエルシー
发明人： DUBRUL WILLIAM R , SEYBOLD BRENT D , MATHIS MARK L , LEOPOLD PHILLIP M
IPC分类号： A61M25/00 , A61B17/11 , A61B17/22 , A61F2/82 , A61M25/01 , A61M25/10 , A61M29/00 , A61M29/02
CPC分类号： A61B17/22 , A61B17/11 , A61B17/22031 , A61B17/221 , A61B2017/1107 , A61B2017/2212 , A61M25/0119 , A61M25/09 , A61M25/1006 , A61M29/02 , A61M2025/0006 , A61M2025/09125 , A61M2025/09183 , A61M2025/109
摘要： PROBLEM TO BE SOLVED: To provide a medical device that can reduce cost, is simple to use, entails a procedure with which the medical profession is familiar so that the skills that have been learned from previous experience will continue to have applicability, removes blockages, and achieves a high degree of safety. SOLUTION: A catheter assembly includes a catheter having a proximal catheter end, a distal catheter end, a lumen, and an outer catheter surface. The catheter assembly also includes a material-directing element, movable between radially expanded and radially collapsed states, secured to and extending past the distal catheter end. The material-directing element has an axial length when in the radially collapsed state. A dilator includes a hollow shaft within the lumen of the catheter. The hollow shaft has an outer shaft surface, a proximal shaft end, a distal shaft end and a recessed region in the outer shaft surface at the distal shaft end. The recessed region and the material-directing element are generally aligned with one another. A compression element covers the material-directing element to temporarily retain the material-directing element in a radially collapsed state. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供可以降低成本，使用简单的医疗设备需要医学界熟悉的程序，以便从以前的经验中学到的技能将继续适用，消除堵塞，达到高安全性。解决方案：导管组件包括具有近端导管端，远侧导管端，内腔和外导管表面的导管。导管组件还包括材料引导元件，其可在径向膨胀和径向塌缩状态之间移动，固定到远端导管末端并延伸穿过远端导管末端。材料引导元件在处于径向塌缩状态时具有轴向长度。扩张器包括在导管内腔内的中空轴。空心轴在远端轴端的外轴面具有外轴面，近端轴端，远端轴端部和凹部区域。凹陷区域和材料引导元件通常彼此对准。压缩元件覆盖材料引导元件以暂时保持材料引导元件处于径向折叠状态。版权所有（C）2011，JPO＆INPIT

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