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1. 发明授权

EP2357168B1 METHOD FOR PRODUCING FLUOROSULFURIC ACID ESTER 有权
标题翻译：用于生产FLUOR硫酸酯的盐
公开(公告)号：EP2357168B1
公开(公告)日：2013-07-17
申请号：EP09821963.7
申请日：2009-10-15
申请人： Central Glass Company, Limited
发明人： Akihiro ISHII , Manabu YASUMOTO
IPC分类号： C07C303/28 , C07C305/26 , C07D207/416 , C07B53/00 , C07C303/24 , C07D207/16
CPC分类号： C07D207/16 , C07B53/00 , C07C303/24 , C07C305/26

2. 发明公开

EP2238123A1 ADDITION REACTION TO FLUOROALLYLFLUOROSULFATE 有权
标题翻译：添加反应为氟代氟硅酸盐
公开(公告)号：EP2238123A1
公开(公告)日：2010-10-13
申请号：EP08866458.6
申请日：2008-12-17
申请人： Solvay Solexis S.p.A.
发明人： MARCHIONNI, Giuseppe , TORTELLI, Vito
IPC分类号： C07D317/42 , C07C43/17 , C07C303/30 , C07C305/26 , C08F261/06 , C08F214/18
CPC分类号： C07D317/42 , C07C41/24 , C07C51/58 , C07C303/24 , C08F214/18 , C08F259/08 , C07C59/135 , C07C305/26 , C07C43/126
摘要： The invention pertains to a process for preparing compounds of formula (I-A) or (I-B) here below: by reaction of perfluoroallylfluorosulfate (FAFS) of formula (II): with at least one hypofluorite of formula (II-A) or (II-B): wherein: RF in formulae (I-A) and (II-A) is a monovalent fluorocarbon C1-C20 group, optionally comprising oxygen catenary atoms, optionally comprising functional groups comprising heteroatoms (e.g. -SO2F groups); R'F in formulae (I-B) and (II-B) is a divalent fluorocarbon C-1-C6 group, preferably a group of formula (III): wherein X1 and X2, equal to or different from each other, are independently a fluorine atom or a C1-C3 fluorocarbon group. The FAFS-hypofluohte adducts of formulae (I-A) and (I-B) can be produced with high selectivity so as to access useful intermediates which can further be reacted taking advantage of the un-modified fluorosulfate group chemistry.
摘要翻译：本发明涉及制备下式（IA）或（IB）化合物的方法：通过式（II）的全氟烯基氟代硫酸盐（FAFS）与至少一种式（II-A）或（II- B）：其中：式（IA）和（II-A）中的RF是任选地包含氧链原子的单价碳氟化合物C1-C20基团，任选地包含包含杂原子（例如-SO 2 F基团）的官能团; 式（IB）和（II-B）中的R'F是二价碳氟C 1 -C 6基团，优选式（III）的基团：其中X 1和X 2彼此相同或不同，独立地为氟原子或C1-C3氟碳基团。式（I-A）和（I-B）的FAFS-次氟酸加合物可以以高选择性生产以获得有用的中间体，其可以利用未改性的氟代硫酸盐基团化学物质进一步反应。

3. 发明公开

EP0880518A4 A PROCESS OF MAKING 3-PHENYL-1-METHYLENEDIOXYPHENYL-INDANE-2-CARBOXYLIC ACID DERIVATIVES 失效
标题翻译：制备3-苯基-1-甲二氧苯基 - 茚满-2-羧酸衍生物的方法
公开(公告)号：EP0880518A4
公开(公告)日：1999-07-28
申请号：EP96940864
申请日：1996-11-08
申请人： SMITHKLINE BEECHAM CORP
发明人： ANDEMICHAEL YEMANE WOLDESELASS , BAINE NEIL HOWARD , CLARK WILLIAM MORROW , KOWALSKI CONRAD JOHN , MCGUIRE MICHAEL ANTHONY , MILLS ROBERT JOHN
IPC分类号： C07D317/54 , A61K31/435 , C07B53/00 , C07C45/46 , C07C45/71 , C07C65/03 , C07C65/21 , C07C65/24 , C07C305/26 , C07C309/65 , C07D233/38 , C07D317/60 , C07D405/04 , C07D405/08 , C07D213/26 , C07D213/30 , C07D213/54 , C07D317/50 , C07D317/52
CPC分类号： C07D405/08 , C07C45/46 , C07C45/71 , C07C65/03 , C07C65/21 , C07C65/24 , C07C305/26 , C07C309/65 , C07D233/38 , C07D317/60 , C07C49/84

4. 发明授权

EP4043433B1 BISSULFONATE COMPOUND, PREPARATION METHOD THEREFOR, ELECTROLYTE SOLUTION AND ENERGY STORAGE DEVICE 有权
公开(公告)号：EP4043433B1
公开(公告)日：2024-03-20
申请号：EP20867884.7
申请日：2020-09-17
发明人： CAO, Gejin , FAN, Weizhen , FAN, Chaojun , XU, Lei , XIN, Yong , ZHAO, Jingwei
IPC分类号： C07C303/28 , C07C309/65 , H01M10/0567 , C07C303/22 , C07C305/26

5. 发明公开

EP2727905A1 PROCESS FOR PRODUCING FLUOROSULFURIC ACID AROMATIC-RING ESTERS 审中-公开
标题翻译： VERFAHREN ZUR HERSTELLUNG AROMATISCHER RINGESTER AUSFLUORSCHWEFELSÄURE
公开(公告)号：EP2727905A1
公开(公告)日：2014-05-07
申请号：EP12804675.2
申请日：2012-06-15
申请人： CENTRAL GLASS COMPANY, LIMITED
发明人： ISHII, Akihiro , ISHIMARU, Takehisa , YAMAZAKI, Takako , YASUMOTO, Manabu
IPC分类号： C07C303/24 , C07C305/26
CPC分类号： C07C303/24 , C07C305/26
摘要： A production process of a fluorosulfuric acid aromatic-ring ester according to the present invention includes reaction of an aromatic-ring hydroxyl compound with sulfuryl fluoride (SO 2 F 2 ) in the presence of a tertiary amine except pyridine and methylpyridine. The sulfuryl fluoride, used as the reactant in the production process according to the present invention, is widely adapted as a fumigant and is easily available on a large scale. Further, the target compound can be obtained rapidly with a high yield under moderate reaction conditions in the production process according to the present invention. In this way, all of the prior art problems can be solved in the production process according to the present invention. The production process according to the present invention is thus particularly useful for industrial production of the fluorosulfuric acid aromatic-ring ester.
摘要翻译：根据本发明的氟代硫酸芳环酯的制备方法包括在除了吡啶和甲基吡啶之外的叔胺存在下，芳环羟基化合物与硫酰氟（SO 2 F 2）的反应。在根据本发明的生产方法中用作反应物的硫酰氟被广泛地用作熏蒸剂，并且容易获得大量。此外，在本发明的制备方法中，在中等反应条件下，可以快速获得目标化合物。以这种方式，可以在根据本发明的制造方法中解决所有现有技术问题。因此，根据本发明的制备方法对于工业生产氟代硫酸芳环酯特别有用。

6. 发明授权

EP1716096B1 SYNTHESIS OF STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS 有权
标题翻译： SECONDARY的合成受阻氨基醚醇
公开(公告)号：EP1716096B1
公开(公告)日：2012-05-02
申请号：EP05712481.0
申请日：2005-02-01
申请人： ExxonMobil Research and Engineering Company
发明人： SISKIN, Michael , KATRITZKY, Alan, Roy , KIRICHENKO, Kostyantyn, Mykolayevich
IPC分类号： C07C303/26 , C07C303/24 , C07C213/02 , C07C213/08 , C07C217/08 , C07C305/10 , C07C305/26
CPC分类号： C07C303/24 , C07C213/02 , C07C213/08 , C07C305/10 , C07C305/26 , C07C217/08
摘要： Severely sterically hindered secondary aminoether alcohols are prepared by reacting an organic carboxylic acid or alkali metal salt of an organic carboxylic acid with a sulfonyl halide, a sulfuryl halide, a mixed sulfuryl ester halide or a mixed sulfuryl amide halide to yield a sulfonic-carboxylic anhydride compound which is then reacted with a dioxane to cleave the ring of the dioxane, yielding a cleavage product which cleavage product is then aminated with an alkylamine and hydrolyzed with base to yield the severely sterically hindered secondary aminoether alcohol.

7. 发明公开

EP2357168A1 METHOD FOR PRODUCING FLUOROSULFURIC ACID ESTER 有权
标题翻译： VERFAHREN ZUR HERSTELLUNG VONFLUORSCHWEFELSÄUREESTER
公开(公告)号：EP2357168A1
公开(公告)日：2011-08-17
申请号：EP09821963.7
申请日：2009-10-15
申请人： Central Glass Company, Limited
发明人： Akihiro ISHII , Manabu YASUMOTO
IPC分类号： C07C303/28 , C07C305/26 , C07D207/416 , C07B53/00
CPC分类号： C07D207/16 , C07B53/00 , C07C303/24 , C07C305/26
摘要： Fluorosulfuric acid esters can be produced by reacting alcohols with sulfuryl fluoride (SO 2 F 2 ) in the presence of a base and water. As a substrate thereof, optically active secondary alcohols are preferable, and optically active α-hydroxyesters and optically active 4-hydroxyprolines are particularly preferable. By performing the reaction in a two-phase system in the presence of a reaction solvent immiscible with water, a desired reaction proceeds particularly well. The present invention is a production method solving all the problems involved in conventional techniques while being industrially practicable.
摘要翻译：氟硫酸酯可以通过在碱和水的存在下使醇与硫酰氟（SO 2 F 2）反应来制备。作为其基材，优选光学活性仲醇，特别优选光学活性的±羟基酯和光学活性的4-羟基脯氨酸。通过在与水不混溶的反应溶剂的存在下在两相体系中进行反应，期望的反应进行得很好。本发明是在工业上可行的情况下解决常规技术中涉及的所有问题的生产方法。

8. 发明授权

EP2238123B1 ADDITION REACTION TO FLUOROALLYLFLUOROSULFATE 有权
标题翻译：加成反应FLUOROALLYLFLUOROSULFAT
公开(公告)号：EP2238123B1
公开(公告)日：2011-07-13
申请号：EP08866458.6
申请日：2008-12-17
申请人： Solvay Solexis S.p.A.
发明人： MARCHIONNI, Giuseppe , TORTELLI, Vito
IPC分类号： C07D317/42 , C07C43/17 , C07C303/30 , C07C305/26 , C08F261/06 , C08F214/18
CPC分类号： C07D317/42 , C07C41/24 , C07C51/58 , C07C303/24 , C08F214/18 , C08F259/08 , C07C59/135 , C07C305/26 , C07C43/126
摘要： The invention pertains to a process for preparing compounds of formula (I-A) or (I-B) here below: by reaction of perfluoroallylfluorosulfate (FAFS) of formula (II): with at least one hypofluorite of formula (II-A) or (II-B): wherein: RF in formulae (I-A) and (II-A) is a monovalent fluorocarbon C1-C20 group, optionally comprising oxygen catenary atoms, optionally comprising functional groups comprising heteroatoms (e.g. -SO2F groups); R'F in formulae (I-B) and (II-B) is a divalent fluorocarbon C-1-C6 group, preferably a group of formula (III): wherein X1 and X2, equal to or different from each other, are independently a fluorine atom or a C1-C3 fluorocarbon group. The FAFS-hypofluohte adducts of formulae (I-A) and (I-B) can be produced with high selectivity so as to access useful intermediates which can further be reacted taking advantage of the un-modified fluorosulfate group chemistry.

9. 发明公开

EP1716096A4 SYNTHESIS OF STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS 有权
标题翻译： SECONDARY的合成受阻氨基醚醇
公开(公告)号：EP1716096A4
公开(公告)日：2008-06-25
申请号：EP05712481
申请日：2005-02-01
申请人： EXXONMOBIL RES & ENG CO
发明人： SISKIN MICHAEL , KATRITZKY ALAN ROY , KIRICHENKO KOSTYANTYN MYKOLAYE
IPC分类号： C07C213/00 , C07C213/02 , C07C213/08 , C07C303/24 , C07C305/10 , C07C305/26
CPC分类号： C07C303/24 , C07C213/02 , C07C213/08 , C07C305/10 , C07C305/26 , C07C217/08
摘要： Severely sterically hindered secondary aminoether alcohols are prepared by reacting an organic carboxylic acid or alkali metal salt of an organic carboxylic acid with a sulfonyl halide, a sulfuryl halide, a mixed sulfuryl ester halide or a mixed sulfuryl amide halide to yield a sulfonic-carboxylic anhydride compound which is then reacted with a dioxane to cleave the ring of the dioxane, yielding a cleavage product which cleavage product is then aminated with an alkylamine and hydrolyzed with base to yield the severely sterically hindered secondary aminoether alcohol.

10. 发明授权

EP0880518B1 A PROCESS OF MAKING 3-PHENYL-1-METHYLENEDIOXYPHENYL-INDANE-2-CARBOXYLIC ACID DERIVATIVES 失效
标题翻译：制备3-苯基-1-甲二氧苯基 - 茚满-2-羧酸衍生物的方法
公开(公告)号：EP0880518B1
公开(公告)日：2003-04-02
申请号：EP96940864.0
申请日：1996-11-08
申请人： SMITHKLINE BEECHAM CORPORATION
发明人： ANDEMICHAEL, Yemane, Woldeselassie , BAINE, Neil, Howard , CLARK, William, Morrow , KOWALSKI, Conrad, John , McGUIRE, Michael, Anthony , MILLS, Robert, John
IPC分类号： C07D405/08 , C07D317/60 , C07D317/52 , C07D317/50 , C07D233/38 , C07D213/54 , C07D213/30 , C07D213/26 , C07C309/65 , C07C45/46 , C07C45/71 , C07C65/03 , C07C65/21 , C07C65/24 , C07C305/26
CPC分类号： C07D405/08 , C07C45/46 , C07C45/71 , C07C65/03 , C07C65/21 , C07C65/24 , C07C305/26 , C07C309/65 , C07D233/38 , C07D317/60 , C07C49/84
摘要： Invented is an improved process for preparing aromatic ring-fused cyclopentane derivatives. Preferred compounds prepared by this invention are indane carboxylates and cyclopentano[b]pyridine derivatives. The most preferred compounds prepared by this invention are (+)(1S, 2R, 3S)-3-[2-(2-hydroxyeth-1-yloxy)-4-methoxyphenyl]-1-(3,4-methylenedioxyphenyl)-5-(prop-1-yloxy)indane-2-carboxylic acid and pharmaceutically acceptable salts thereof and (+)(1S, 2R, 3S)-3-(2-carboxymethoxy-4-methoxyphenyl)-1-(3,4-methylenedioxyphenyl)-5-(prop-1-yloxy)indane-2-carboxylic acid and pharmaceutically acceptable salts thereof. Also invented are novel intermediates useful in preparing these compounds.

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