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    • 6. 发明公开
    • Tomographic phase microscope
    • Tomographisches Phasenmikroskop
    • EP2998776A1
    • 2016-03-23
    • EP14185718.5
    • 2014-09-22
    • Nanolive SA
    • Cotte, YannCotte, Pierre-AlainEquis, SebastienKern, Andreas
    • G02B21/14G02B21/36G01N21/45G03H1/08
    • G01B9/02047G01B9/02068G01N21/453G02B21/14G02B21/367G02B26/0816G02B26/108G03H1/0443G03H1/0866G03H1/265G03H1/268G03H2001/0038G03H2001/005G03H2001/0456
    • Microscope (2) comprising a coherent light source (4) producing a coherent light beam (7), a light beam guide system (6) comprising a beam splitter (14) configured to split the coherent light beam (7) into a reference beam (7a) and a sample illumination beam (7b), a sample holder (18) configured to hold a sample (1) to be observed, a sample illumination device (28) configured to direct the sample illumination beam (7b) through the sample and into a microscope objective (37), a beam reuniter (16) configured to reunite the reference beam and sample illumination beam after passage of the sample illumination beam through the sample to be observed, and a light sensing system (8) configured to capture at least phase and intensity values of the coherent light beam downstream of the beam reuniter. The microscope further comprises a control system configured to generate a mirror angle control signal to control an angle of a pivotally actionable mirror, the mirror angle control signal being based at least partially on a signal received from the light sensing system and generated by the light beam.
    • 包括产生相干光束(7)的相干光源(4)的显微镜(2),包括分束器(14)的光束引导系统(6),其被配置为将相干光束(7)分成参考光束 (7a)和样品照明光束(7b),被配置为保持待观察的样品(1)的样品保持器(18),被配置为将样品照射光束(7b)引导通过样品的样品照射装置(28) 并且进入显微镜物镜(37),束重构器(16),其被配置为在通过待观察的样本之后使参考光束和样本照明光束重聚;以及光感测系统(8),被配置为捕获 至少相干光束的相位和强度值在光束复原器的下游。 显微镜还包括配置成产生镜角控制信号以控制可转动的镜子的角度的控制系统,镜角控制信号至少部分地基于从光感测系统接收并由光束产生的信号 。