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1. 发明公开

EP3408679A1 SYSTEM AND METHOD FOR OPTIMIZED DIFFUSION--WEIGHTED IMAGING 审中-公开
公开(公告)号：EP3408679A1
公开(公告)日：2018-12-05
申请号：EP17744789.3
申请日：2017-01-25
申请人： The Regents of the University of California
发明人： ENNIS, Daniel B. , ALIOTTA, Eric , WU, Holden H.
IPC分类号： G01R33/56
CPC分类号： G01R33/56341 , G01R33/5614 , G01R33/5616
摘要： A system and method for optimized diffusion-weighted imaging is provided. In one aspect, the method includes providing a plurality of constraints for imaging a target at a selected diffusion weighting, and applying an optimization framework to generate an optimized diffusion encoding gradient waveform satisfying the plurality of constraints. The method also includes performing, using the MRI system, a pulse sequence comprising the optimized diffusion encoding gradient waveform to generate diffusion-weighted data, and generating at least one image of the target using the diffusion-weighted data.

2. 发明公开

EP3385742A1 METHOD AND APPARATUS FOR IDENTIFYING AT LEAST ONE MATERIAL COMPRISED IN A VOXEL 审中-公开
公开(公告)号：EP3385742A1
公开(公告)日：2018-10-10
申请号：EP17165079.9
申请日：2017-04-05
申请人： Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. , Julius-Maximilians-Universität Würzburg
发明人： Blaimer, Martin , Jakob, Peter
IPC分类号： G01R33/50 , G01R33/561
CPC分类号： G01R33/5614 , G01R33/50
摘要： The present invention discloses a method (500) for identifying at least one material (115) comprised in a voxel (120). The disclosed MR data acquisition method uses the transient phase of balanced steady-state free precession (bSSFP), which allows to simultaneously acquire quantitative information about longitudinal and transversal relaxation times T1 and T2 and relative proton density in multi-component systems. In one embodiment , these values are derived by combining signals from multiple acquisitions each of whom being realized by radio-frequency excitation pulses with different flip angles.The method is thus suitable for quantitative MRI T1 and T2 mapping. The method comprises a step of Reading in (510) at least a first (S 1 ) and a second (S 2 ) signal train, the first (S 1 ) and second (S 2 ) signal train each representing magnetization values being determined after the material (115) in the voxel (120) was exposed to predefined radio-frequency pulses (P 1 , P 2 ), wherein the predefined radio-frequency pulses (P 1 ) exposed to the material (115) in the voxel (120) before or during measuring the first signal train (S 1 ) differs in at least one parameter (α) from the radio-frequency pulses (P 2 ) exposed to the material (115) in the voxel (120) before or during measuring the second signal train (S 2 ). Furthermore, the method comprises a step of Performing (520) at least a time-domain-frequency-domain transformation, such as e.g. inverse Laplace transformation, in order to obtain a first (F 1 ) and a second (F 0 ) transformation value, the first transformation value (F 1 ) representing a frequency domain signal resulting from the time-domain-frequency-domain transformation on the basis of at least the first signal train (S 1 ) and the second transformation value (F 0 ) representing a frequency domain signal resulting from the time-domain-frequency-domain transformation on the basis of at least the second signal train (S 2 ). Finally the method comprises a step of Specifying (530) the material (115) using the first (F 1 ) and second (F 0 ) transformation values or values derived from the first (F 1 ) and/or second (F 0 ) transformation value, in order to identify the material (115).

3. 发明公开

EP3324199A1 BSSFP-MR-ANGIOGRAPHIE MIT VERWENDUNG EINES HF-PULSES MIT RAMPENFÖRMIGEN ANREGUNGSPROFIL 有权转让
公开(公告)号：EP3324199A1
公开(公告)日：2018-05-23
申请号：EP17181239.9
申请日：2017-07-13
申请人： Siemens Healthcare GmbH
发明人： Schmitt, Peter , Speier, Peter
IPC分类号： G01R33/561 , G01R33/563
CPC分类号： G01R33/5635 , G01R33/5614
摘要： Verfahren zur Aufnahme von Magnetresonanzdaten aus einem aufzunehmenden Bildgebungsvolumen (1) eines Patienten, in dem Flüssigkeit, insbesondere Blut, bewegt ist, mittels einer bSSFP-Magnetresonanzsequenz, bei der innerhalb des Bildgebungsvolumens (1) befindliche Spins mittels eines Hochfrequenzpulses zyklisch angeregt werden, mit einer Magnetresonanzeinrichtung (17), wobei als Hochfrequenzpuls ein einen räumlich innerhalb des Bildgebungsvolumens (1) veränderlichen Flipwinkel der Spins einstellender Rampenpuls verwendet wird, wobei der Flipwinkel auf einer Seite (4), von der die Flüssigkeit in das Bildgebungsvolumen (1) einströmt, niedriger gewählt wird als auf der Seite (5), auf der die Flüssigkeit ausströmt, und monoton ansteigt.

4. 发明公开

EP3116390A4 SYSTEM AND METHOD FOR FREE RADICAL IMAGING 审中-公开
公开(公告)号：EP3116390A4
公开(公告)日：2017-11-29
申请号：EP15762153
申请日：2015-03-13
申请人： MASSACHUSETTS GEN HOSPITAL
发明人： ROSEN MATTHEW S , SARRACANIE MATHIEU , ARMSTRONG BRANDON
IPC分类号： G01R33/60 , A61B5/055 , G01N24/10 , G01R33/28 , G01R33/34 , G01R33/381 , G01R33/44 , G01R33/56 , G01R33/561 , G01R33/62
CPC分类号： G01R33/445 , G01N24/10 , G01R33/288 , G01R33/34053 , G01R33/381 , G01R33/56 , G01R33/5601 , G01R33/5611 , G01R33/5614 , G01R33/60 , G01R33/62
摘要： A system and method for performing a medical imaging process includes arranging a subject to be imaged in a magnetic resonance imaging (MRI) system and performing, using the MRI system, a magnetic resonance (MR) imaging pulse sequence. While performing the MR pulse sequence, electron paramagnetic resonance (EPR) pulses are performed at least during the application of the phase encoding gradients or only during the MR pulse sequence. Data is acquired that corresponds to signals from the subject excited by the MR pulse sequence and the EPR pulses. At least one image of the subject is reconstructed from the data.

5. 发明公开

EP3093677A1 TIME-DOMAIN MRI 审中-公开
标题翻译： EINERZEITDOMÄNE的MAGNETRESONANZTOMOGRAFIE
公开(公告)号：EP3093677A1
公开(公告)日：2016-11-16
申请号：EP15171708.9
申请日：2015-06-11
申请人： UMC Utrecht Holding B.V.
发明人： Sbrizzi, Alessandro , van den Berg, Cornelis Antonius Theodorus , van der Toorn, Annette
IPC分类号： G01R33/24 , G01R33/50 , G01R33/561
CPC分类号： G01R33/50 , G01R33/243 , G01R33/246 , G01R33/561 , G01R33/5613 , G01R33/5614
摘要： A system for performing time-domain magnetic resonance imaging comprises an excitation device for transiently exciting a sample thereby causing the sample to emit an emitting signal. A receiving coil receives the emitting signal. A simulated signal of the receiving coil is generated in a time domain, based on a plurality of spatial parameter distributions, wherein the spatial parameter distributions include a spatial distribution of a magnetization, wherein the spatial parameter distributions further include at least one of a spatial distribution of a material property of a material of the sample and a spatial distribution of an electromagnetic field. An objective function is based on a difference between the received emitting signal and the simulated signal in the time domain. The plurality of spatial parameter distributions are fitted based on the objective function.
摘要翻译：用于执行时域磁共振成像的系统包括用于瞬态激励样品从而使样品发射发射信号的激励装置。接收线圈接收发射信号。基于多个空间参数分布，在时域中产生接收线圈的模拟信号，其中空间参数分布包括磁化的空间分布，其中空间参数分布进一步包括空间分布中的至少一个的样品的材料的材料性质和电磁场的空间分布。目标函数是基于接收到的发射信号和时域中的模拟信号之间的差异。基于目标函数拟合多个空间参数分布。

6. 发明授权

EP2063282B1 MR imaging of flowing matter using steady state free precession 有权
标题翻译：流动介质在平衡时自由进动的MR成像
公开(公告)号：EP2063282B1
公开(公告)日：2013-01-16
申请号：EP08020187.4
申请日：2008-11-19
申请人： Kabushiki Kaisha Toshiba , Toshiba Medical Systems Corporation
发明人： Yui, Masao
IPC分类号： G01R33/561 , G01R33/563
CPC分类号： G01R33/5635 , G01R33/5614 , G01R33/56316 , G01R33/56509 , G01R33/5673

7. 发明授权

EP1825808B1 MAGNETIC RESONANCE IMAGING SYSTEM 有权
标题翻译：磁共振系统
公开(公告)号：EP1825808B1
公开(公告)日：2012-09-19
申请号：EP05727413.6
申请日：2005-03-30
申请人： Keio University
发明人： OSHIO, Koichi
IPC分类号： A61B5/055 , G01R33/567 , G01R33/563 , G01R33/565
CPC分类号： G01R33/5676 , G01R33/4822 , G01R33/4824 , G01R33/4835 , G01R33/5614 , G01R33/5635 , G01R33/56509 , G01R33/5673

8. 发明公开

EP2138860A1 Spin tagged SSFP MRI 审中-公开
标题翻译： Spin-markierte SSFP MRI
公开(公告)号：EP2138860A1
公开(公告)日：2009-12-30
申请号：EP09163851.0
申请日：2009-06-26
申请人： ALLEGHENY-SINGER RESEARCH INSTITUTE
发明人： Doyle, Mark , Biederman, Robert
IPC分类号： G01R33/563
CPC分类号： G01R33/56333 , G01R33/5614 , G01R33/5616 , G01R33/56325
摘要： A magnetic resonance imager for forming images of a moving portion of a patient includes imaging coils. The imager includes a computer that causes the imaging coils to apply continuously steady-state free precession to k-space of a magnetic resonance image series of the patient and acquire the image series, and generates images from the image series. A method for forming images of a moving portion of a patient includes the steps of applying continuously steady-state free precession to k-space of a magnetic resonance image series of a patient. There is the step of acquiring the image series. There is the step of generating images from the image series. A method for forming images of a patient includes the steps of triggering a steady-state free precision imaging sequence to an ECG r wave of cardiac cycles of the patient. There is the step of performing the steady-state free precision imaging sequence with imaging coils of a magnetic resonance imaging scanner such that data for a series of k-space data sets associated with the imaging sequence are acquired in a manner that is time resolved through the cardiac cycle, with data acquired over a number of consecutive cardiac cycles. A computer program embodied on a computer readable medium to form an image of a patient with an MRI.
摘要翻译：用于形成患者的运动部分的图像的磁共振成像器包括成像线圈。成像器包括使得成像线圈对患者的磁共振图像系列的k空间进行连续稳态自由进动的计算机，并获取图像序列，并且从图像序列生成图像。用于形成患者的运动部分的图像的方法包括以下步骤：对患者的磁共振图像系列的k空间施加连续的稳态自由进动。获取图像系列的步骤。有从图像系列生成图像的步骤。用于形成患者图像的方法包括以下步骤：触发稳定状态的自由精确成像序列到患者心脏周期的ECG r波。执行具有磁共振成像扫描仪的成像线圈的稳态自由精确成像序列的步骤，使得以与时间分辨的方式获取与成像序列相关联的一系列k空间数据集的数据心脏周期，数据采集多个连续的心动周期。一种体现在计算机可读介质上以形成患有MRI的患者的图像的计算机程序。

9. 发明公开

EP1825808A4 MAGNETIC RESONANCE IMAGING SYSTEM 有权
标题翻译： MAGNETRESONANZTOMOGRAPHIESYSTEM
公开(公告)号：EP1825808A4
公开(公告)日：2009-11-11
申请号：EP05727413
申请日：2005-03-30
申请人： UNIV KEIO
发明人： OSHIO KOICHI
IPC分类号： A61B5/055 , G01R33/48 , G01R33/28 , G01R33/54 , G01R33/563 , G01R33/565 , G01R33/567
CPC分类号： G01R33/5676 , G01R33/4822 , G01R33/4824 , G01R33/4835 , G01R33/5614 , G01R33/5635 , G01R33/56509 , G01R33/5673

10. 发明公开

EP1825808A1 MAGNETIC RESONANCE IMAGING SYSTEM 有权
标题翻译： MAGNETRESONANZTOMOGRAPHIESYSTEM
公开(公告)号：EP1825808A1
公开(公告)日：2007-08-29
申请号：EP05727413.6
申请日：2005-03-30
申请人： Keio University
发明人： OSHIO, Koichi
IPC分类号： A61B5/055 , G01R33/567
CPC分类号： G01R33/5676 , G01R33/4822 , G01R33/4824 , G01R33/4835 , G01R33/5614 , G01R33/5635 , G01R33/56509 , G01R33/5673
摘要： A magnetic resonance imaging system includes a high-frequency magnetic field generating unit (8T) for generating and applying a high-frequency magnetic field to a subject placed in a static magnetic field, a gradient magnetic field generating unit (4) for generating a gradient magnetic field to be superimposed on the static magnetic field, and a sequencer (5) for controlling the high-frequency magnetic field generating unit and the gradient magnetic field generating unit to acquire, within a specified part of the heartbeat of the subject, MR data that pertains to a plane through which an axis substantially identical to the body axis of the subject in a k-space extends, and to cause the plane to rotate, at every heartbeat, about the axis substantially identical to the body axis.
摘要翻译：磁共振成像系统包括：高频磁场产生单元（8T），用于产生并施加高频磁场到放置在静态磁场中的被摄体;梯度磁场产生单元（4），用于产生梯度磁场叠加在静磁场上;以及定序器（5），用于控制高频磁场产生单元和倾斜磁场产生单元，以在对象的心跳的指定部分内获取MR数据涉及一个平面，通过该平面，在k空间中基本上与被检者的身体轴线基本相同的轴线延伸，并且使得平面在每个心跳处围绕基本上与身体轴线相同的轴线旋转。

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