专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

EP3072954B1 HERICIUM ERINACEUM-DERIVED LECTIN SPECIFIC FOR SIALIC ACID LINKAGE 有权
标题翻译： Hericium ERINACEUM来源的特异性唾液酸连接的LECTIN
公开(公告)号：EP3072954B1
公开(公告)日：2017-12-20
申请号：EP14862325.9
申请日：2014-11-14
申请人： Korea Research Institute of Bioscience and Biotechnology
发明人： KIM, Seonghun
IPC分类号： C12N1/14 , C07K14/37 , C07K14/42
CPC分类号： C07K14/375 , C07K14/37 , G01N33/582 , G01N33/6848 , G01N2333/42
摘要： The present invention concerns lectins isolated from the fruiting body of a novel Hericium erinaceum (deposit number: KCTC 12499BP) NEU-1 L strain which bind specifically to sialic acid. The invention further pertains to uses of such lectinsn abd to processes for their preparation thereby. The lectin of the present invention can be useful as an active ingredient of a composition or a kit for measuring or detecting glycoproteins, glycopeptides, glycolipids, sugar precursors or oligosaccharides containing sialic acid moieties, or further for measuring or detecting cell lines, bacteria and viruses containing sialoglycoconjugates.

2. 发明公开

EP3072954A4 HERICIUM ERINACEUM-DERIVED LECTIN SPECIFIC FOR SIALIC ACID LINKAGE 有权
标题翻译： FÜRSIALINSÄUREBINDUNGSPEZIFISCHES LECTIN AUS HERICIUM ERINACEUM
公开(公告)号：EP3072954A4
公开(公告)日：2016-10-19
申请号：EP14862325
申请日：2014-11-14
申请人： KOREA RES INST OF BIOSCIENCE
发明人： KIM SEONGHUN
IPC分类号： C12N1/14 , C07K14/37 , C07K14/42
CPC分类号： C07K14/375 , C07K14/37 , G01N33/582 , G01N33/6848 , G01N2333/42
摘要： The present invention concerns lectins isolated from the fruiting body of a novel Hericium erinaceum (deposit number: KCTC 12499BP) NEU-1 L strain which bind specifically to sialic acid. The invention further pertains to uses of such lectinsn abd to processes for their preparation thereby. The lectin of the present invention can be useful as an active ingredient of a composition or a kit for measuring or detecting glycoproteins, glycopeptides, glycolipids, sugar precursors or oligosaccharides containing sialic acid moieties, or further for measuring or detecting cell lines, bacteria and viruses containing sialoglycoconjugates.
摘要翻译：本发明涉及从与唾液酸特异性结合的新型赫氏酵母（保藏号：KCTC 12499BP）NEU-1L菌株的子实体分离的凝集素。本发明进一步涉及这种凝集素abd的用途，因此其制备方法。本发明的凝集素可用作用于测量或检测糖蛋白，糖肽，糖脂，糖前体或含有唾液酸部分的寡糖或进一步用于测量或检测细胞系，细菌和病毒的组合物或试剂盒的活性成分含有sialoglycoconjugates。

3. 发明公开

EP2718459A4 COMPETITION-BASED DETECTION ASSAYS 有权转让
标题翻译： DETEKTIONSARRAYS AUF WETTBEWERBSBASIS
公开(公告)号：EP2718459A4
公开(公告)日：2015-12-16
申请号：EP12797229
申请日：2012-06-08
申请人： SHIRE HUMAN GENETIC THERAPIES
发明人： ROSEMAN DANIEL S
IPC分类号： C12Q1/37
CPC分类号： G01N33/573 , G01N2333/42 , G01N2333/914 , G01N2333/916 , G01N2400/10
摘要： Disclosed herein are methods and kits which are useful for detecting presence of an enzyme and the relative amount of glycan associated with the enzyme in a test sample based upon the enzyme's ability to competitively inhibit the binding of a ligand in such test sample. The present invention provides the ability to evaluate cell culture conditions and optimize the desired glycoform content of recombinantly prepared enzymes.
摘要翻译：本文公开了可用于检测酶的存在和测试样品中与酶相关的聚糖的相对量的方法和试剂盒，其基于酶在竞争性抑制配体在该测试样品中结合的能力。本发明提供了评估细胞培养条件并优化重组制备的酶的所需糖型含量的能力。

4. 发明公开

EP1916525A1 Method for detection of yeast cell wall 审中-公开
标题翻译： Verfahren zum nachweis der zellwand von hefen
公开(公告)号：EP1916525A1
公开(公告)日：2008-04-30
申请号：EP07250240.4
申请日：2007-01-22
申请人： Alltech, Inc.
发明人： Horgan, Karina
IPC分类号： G01N33/566 , G01N33/569
CPC分类号： G01N33/56961 , G01N2333/39 , G01N2333/42 , G01N2400/14
摘要： Methods are provided for detecting the presence of a yeast cell wall in a food or animal feed suspected of containing the yeast cell wall. The method includes the steps of solubilizing the yeast cell wall, adding a lectin which preferentially binds to a mannose component of the solubilized yeast cell wall, detecting the presence of the lectin. In one embodiment, the lectin preferentially binds to an α-linked mannose component of the yeast cell wall. The α-linked mannose component may be an α-(1,3)-linked mannose or an α-(1,6)-linked mannose, and the yeast cell wall may be derived from Saccharomyces cerevisiae. Kits for accomplishing the method are described, which include a labeled lectin which preferentially binds to a mannose component of the solubilized yeast cell wall and reagents for detecting the labeled lectin.
摘要翻译：提供了用于检测怀疑含有酵母细胞壁的食物或动物饲料中酵母细胞壁的存在的方法。该方法包括增溶酵母细胞壁，加入优先结合溶解酵母细胞壁的甘露糖组分的凝集素，检测凝集素的存在的步骤。在一个实施方案中，凝集素优先结合酵母细胞壁的±连接的甘露糖组分。 ±连接的甘露糖组分可以是± - （1,3）连接的甘露糖或± - （1,6）连接的甘露糖，并且酵母细胞壁可以衍生自酿酒酵母（Saccharomyces cerevisiae）。描述了用于实现该方法的试剂盒，其包括优先结合溶解的酵母细胞壁的甘露糖组分的标记的凝集素和用于检测标记的凝集素的试剂。

5. 发明授权

EP1456663B1 VERFAHREN ZUR BESTIMMUNG DER RESPONSIVITÄT EINES INDIVIDUUMS FÜR MISTELLEKTIN 有权
标题翻译：方法用于确定个体的响应到槲寄生凝集素
公开(公告)号：EP1456663B1
公开(公告)日：2007-05-09
申请号：EP02795260.5
申请日：2002-12-20
申请人： Viscum AG
发明人： MÜTHING, Johannes , PETER-KATALINIC, Jasna , LANGER, Martin , MÖCKEL, Babette , ECK, Jürgen
IPC分类号： G01N33/566 , C07K16/28 , G01N33/66 , C12Q1/48
CPC分类号： C12Q1/48 , C07K16/18 , G01N33/566 , G01N33/66 , G01N2333/42 , G01N2400/00 , G01N2800/52
摘要： A method for determination of the responsiveness of an individual to mistletoe lectin or to (an) individual mistletoe lectin chain is disclosed, whereby the expression of a membrane-bound receptor for mistletoe lectin is characteristic for a corresponding responsiveness. The receptor is characterised by a terminal N-acetylneuraminic acid (Neu5Ac) bonded to a galactose by means of a glycosidic alpha-2,6 bond. Another method for the determination of the responsiveness to mistletoe lectin is also disclosed based on the detection of a sialyl transferase.

6. 发明公开

EP1632777A3 Polysaccharide structure and sequence determination 审中-公开
标题翻译：确定多糖的结构和序列
公开(公告)号：EP1632777A3
公开(公告)日：2006-06-14
申请号：EP05023256.0
申请日：2000-05-04
申请人： Procognia (Israel) Ltd.
发明人： Markman, Ofer
IPC分类号： G01N33/53 , C12Q1/34
CPC分类号： G01N33/66 , C12Q1/34 , G01N33/5308 , G01N2333/42 , G01N2333/924 , G01N2400/00 , G01N2400/02 , G01N2400/10 , Y10T436/143333
摘要： A method for the structural analysis of a saccharide is disclosed, comprising: a) providing on a surface a plurality of essentially sequence- and/or site-specific binding agents; b) contacting said surface with a saccharide to be analyzed, or with a mixture comprising a plurality of fragments of said saccharide; c) washing or otherwise removing unbound saccharide or saccharide fragments; d) adding to the surface obtained in step c) an essentially sequence- and/or site-specific marker, or a mixture of essentially sequence- and/or site-specific markers; e) acquiring one or more images of the markers that are bound to said surface; and f) deriving information related to the identity of the saccharide being analyzed from said image. The invention further provides a solid support comprising in a pre-defined order a plurality of visual or otherwise detectable markers representative of a saccharide or saccharide sequence or fragment, as well as methods and software for choosing a set of essentially sequence-specific markers for use in the method of the invention, methods for obtaining structure-related data of saccharides, and methods and apparatus for analyzing the structure of a saccharide by sequential digestion using a glycosidase or an equivalent thereof.

7. 发明授权

EP1179177B1 POLYSACCHARIDE STRUCTURE AND SEQUENCE DETERMINATION 有权
标题翻译：多糖的结构和序列测定
公开(公告)号：EP1179177B1
公开(公告)日：2005-10-26
申请号：EP00922830.5
申请日：2000-05-04
申请人： Procognia (Israel) Ltd.
发明人： MARKMAN, Ofer
IPC分类号： G01N33/53 , C12Q1/34
CPC分类号： G01N33/66 , C12Q1/34 , G01N33/5308 , G01N2333/42 , G01N2333/924 , G01N2400/00 , G01N2400/02 , G01N2400/10 , Y10T436/143333
摘要： The invention provides a method for the structural analysis of a saccharide, comprising: a) providing on a surface a plurality of essentially sequence- and/or site-specific binding agents; b) contacting said surface with a saccharide to be analyzed, or with a mixture comprising a plurality of fragments of said saccharide; c) washing or otherwise removing unbound saccharide or saccharide fragments; d) adding to the surface obtained in step c) an essentially sequence- and/or site-specific marker, or a mixture of essentially sequence- and/or site-specific markers; e) acquiring one or more images of the markers that are bound to said surface; and f) deriving information related to the identity of the saccharide being analyzed from said image.

8. 发明公开

EP1342067A1 FLOW-THROUGH MEMBRANE ASSAYS FOR CARBOHYDRATES USING LABELED LECTINS 审中-公开
标题翻译：膜流动测定法使用标记的凝集素的碳水化合物
公开(公告)号：EP1342067A1
公开(公告)日：2003-09-10
申请号：EP01992159.2
申请日：2001-12-17
申请人： EY Laboratories Inc.
发明人： CHU, Albert, E.
IPC分类号： G01N21/00
CPC分类号： G01N33/54306 , G01N33/54366 , G01N33/66 , G01N2333/42 , G01N2400/00
摘要： The present invention comprises a method for rapid detection of at least a first carbohydrate in a carbohydrate-containing sample molecule comprising the steps of: retaining the sample molecule on a region of one liquid permeable reaction membrane (14); flowing a solution of first lectin, capable of binding the first carbohhydrate, through the one reaction membrane (14) to bind the firstlectin to the retained first carbohydrate, the lectin being directly conjugated to a label prior to binding to the carbohydrate or being bound to a labeled separate molecule only after the first lectin has been bound to the carbohydrate, and; thereafter, detecting the label bound on the one reaction membrane (14), indicating the presence of the first carbohydrate.

9. 发明公开

EP1206700A1 METHODS FOR ANALYZING PROTEIN BINDING EVENTS 审中-公开
标题翻译：对于分析方法蛋白结合活动
公开(公告)号：EP1206700A1
公开(公告)日：2002-05-22
申请号：EP00950759.1
申请日：2000-07-27
申请人： Signature Bioscience inc.
发明人： HEFTI, John
IPC分类号： G01N33/543
CPC分类号： B82Y10/00 , B82Y30/00 , C12Q1/001 , G01N33/54373 , G01N33/5438 , G01N2333/42 , G01N2333/4712 , G01N2333/723 , G01N2333/924 , G01N2333/96486 , G01N2333/98 , H01J49/04
摘要： The present invention provides a variety of methods of analyzing protein binding events using a system capable of directly detecting protein/ligand complexes based upon the dielectric properties of the complex. The system can be used in a variety of analyses involving protein binding events, such as screening ligand libraries, characterizing protein binding interactions, and identifying ligands. The system can also be utilized in diverse analytical and diagnostic applications.

10. 发明公开

EP0912890A4 DETECTION OF CANCER BY ASSAYING FOR CANCER-SPECIFIC ANTIGENS HAVING LINKED OLIGOSACCHARIDES WHICH ARE AT LEAST TRIANTENNARY 失效
标题翻译： KREBSERKENNUNG DURCH BESTIMMUNG VON ANTIGENEN DIE TRIANTENNARE OLIGOSACCHARIDE TRAGEN
公开(公告)号：EP0912890A4
公开(公告)日：2002-01-02
申请号：EP97928986
申请日：1997-06-13
申请人： MILLENNIUM PHARM INC
发明人： ROBBINS PHILLIPS W , PRAKASH SADHANA
IPC分类号： G01N33/48 , G01N33/53 , G01N33/567 , G01N33/574
CPC分类号： G01N33/57488 , G01N33/57434 , G01N2333/42 , G01N2333/4724 , G01N2333/96455
摘要： A process for assaying for cancer of the prostate, comprising assaying a sample derived from a human for prostate specific antigen having a linked oligosaccharide which is at least triantennary. The assay may employ a binding molecule which binds to oligosaccharides that are at least triantennary, but does not bind to oligosaccharides that are monoantennary or diantennary. Such binding molecule may be a lectin such as PHA-L or an antibody to an oligosaccharide that is at least triantennary.
摘要翻译：一种用于测定前列腺癌的方法，包括测定来源于人的具有至少三临界连接的寡糖的前列腺特异性抗原的样品。该测定可以使用结合分子，所述结合分子与至少三天生的寡糖结合，但不结合寡糖，其是单末端或双螺旋的。这样的结合分子可以是凝血素如PHA-L或至少是三进制的寡糖的抗体。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式