发明公开
EP0912890A4 DETECTION OF CANCER BY ASSAYING FOR CANCER-SPECIFIC ANTIGENS HAVING LINKED OLIGOSACCHARIDES WHICH ARE AT LEAST TRIANTENNARY
失效
基本信息:
- 专利标题： DETECTION OF CANCER BY ASSAYING FOR CANCER-SPECIFIC ANTIGENS HAVING LINKED OLIGOSACCHARIDES WHICH ARE AT LEAST TRIANTENNARY
- 专利标题（中）：KREBSERKENNUNG DURCH BESTIMMUNG VON ANTIGENEN DIE TRIANTENNARE OLIGOSACCHARIDE TRAGEN
- 申请号：EP97928986 申请日：1997-06-13
- 公开(公告)号：EP0912890A4 公开(公告)日：2002-01-02
- 发明人： ROBBINS PHILLIPS W , PRAKASH SADHANA
- 申请人： MILLENNIUM PHARM INC
- 专利权人： MILLENNIUM PHARM INC
- 当前专利权人： MILLENNIUM PHARM INC
- 优先权： US2110996 1996-07-03
- 主分类号： G01N33/48
- IPC分类号： G01N33/48 ; G01N33/53 ; G01N33/567 ; G01N33/574
摘要：
A process for assaying for cancer of the prostate, comprising assaying a sample derived from a human for prostate specific antigen having a linked oligosaccharide which is at least triantennary. The assay may employ a binding molecule which binds to oligosaccharides that are at least triantennary, but does not bind to oligosaccharides that are monoantennary or diantennary. Such binding molecule may be a lectin such as PHA-L or an antibody to an oligosaccharide that is at least triantennary.
摘要（中）：
一种用于测定前列腺癌的方法，包括测定来源于人的具有至少三临界连接的寡糖的前列腺特异性抗原的样品。 该测定可以使用结合分子，所述结合分子与至少三天生的寡糖结合，但不结合寡糖，其是单末端或双螺旋的。 这样的结合分子可以是凝血素如PHA-L或至少是三进制的寡糖的抗体。