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    • 7. 发明公开
    • Prevention of crystal formation in liquid solutions during storage by adding a betaine
    • 通过添加甜菜碱的防止储存期间在液体溶液晶体的形成
    • EP2390646A1
    • 2011-11-30
    • EP10164129.8
    • 2010-05-27
    • Biocartis SA
    • Offermans, Paulus H. G.Pierik, AnkeMeijering, Bernadet D. M.Bakker, Frederikus
    • G01N1/30C12Q1/68
    • C09K15/28C09K15/20C12Q1/6806C12Q1/686Y10T428/13C12Q2527/125
    • The present invention relates to the field of improving and stabilizing concentrated solutions and in particular to improving and stabilizing concentrated solutions for the extraction of nucleic acids from sample material. Thus, the present invention, further, relates to the field of molecular biology. The present invention describes the use of betaines for stabilizing organic salts or chaotropic agents in solution which is particularly useful in cases where organic salts or chaotropic agents are present at high concentration such as for example chaotropic agents in buffers for the extraction of nucleic acids from sample material. The present invention describes the corresponding buffers and further relates to processes for the extraction of nucleic acids from sample material as well as processes for the analysis of sample material. Moreover, the present invention relates to kits and cartridges comprising at least one container with the corresponding buffer.
    • 本发明涉及改善和稳定浓溶液的领域,并且尤其涉及改进和用于核酸从样品材料提取稳定浓溶液。 因此,本发明中,进一步,上涉及分子生物学领域。 本发明描述了使用β结晶的用于稳定在溶液中的有机盐或离液剂所有这些是在有机盐或离液剂存在于高浓度的情况下特别有用:如对于实施例的离液剂中缓冲剂用于从样本提取核酸 材料。 本发明描述了对应的缓冲器并且还涉及到用于核酸从样品材料以及处理该萃取样品材料的分析处理。 更过地,本发明涉及试剂盒和磁带盒包括与所述相应的缓冲器中的至少一个容器。