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1. 发明授权

EP3250580B1 SUGAR-DIPEPTIDE CONJUGATES AS FLAVOR MOLECULES 有权转让
公开(公告)号：EP3250580B1
公开(公告)日：2018-10-24
申请号：EP16702371.2
申请日：2016-01-26
申请人： Nestec S.A.
发明人： SMARRITO-MENOZZI, Candice Marie , VITON, Florian , HOFMANN, Thomas , KRANZ, Maximilian
IPC分类号： C07H7/02 , C07K9/00 , A23L2/56
CPC分类号： C07K5/06026 , A23L23/10 , A23L27/2052 , A23L27/21 , A23L27/215 , A23L27/88 , A23V2002/00 , C07H7/02
摘要： The present invention relates to compounds and compositions for use in enhancing flavor and umami taste of food products. Particularly, the present invention relates to compounds of the general formula (I) and compositions comprising them.

2. 发明授权

EP2650289B1 Glycomimetics as pseudomonas Aeruginosa lectin inhibitors 有权转让
标题翻译： Glycomimetie als Pseudomonas aeruginosa-Hemmer
公开(公告)号：EP2650289B1
公开(公告)日：2016-07-27
申请号：EP12002531.7
申请日：2012-04-10
申请人： Universität Konstanz
发明人： Titz, Alexander, Dr.
IPC分类号： C07D309/10 , A61K31/351 , A61P31/04
CPC分类号： C07H15/04 , A61K31/351 , A61K31/7028 , A61K45/06 , C07D309/02 , C07D309/10 , C07D407/12 , C07H7/02 , C07H7/04 , C07H7/06

3. 发明授权

EP2797945B1 2-((2S,3S,4R,5R)-5-((S)-3-AMINO-2-HYDROXYPROP-1-YL)-4-METHOXY-3-(PHENYLSULFONYLMETHYL)TETRAHYDROFURAN-2-YL)ACETALDEHYDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION 失效
标题翻译：（（2S，3S，4R，5R）-5 - （（S）-3-氨基-2-羟基丙-1-基）-4-甲氧基-3-（苯磺酰基甲基）四氢呋喃-2-基）乙醛衍生物和他们的准备过程
公开(公告)号：EP2797945B1
公开(公告)日：2016-03-16
申请号：EP12863099.3
申请日：2012-12-24
申请人： Alphora Research Inc.
发明人： SOUZA, Fabio E.S. , RUDOLPH, Alena , PAN, Ming , GORIN, Boris , ALBERICO, Dino
IPC分类号： C07H9/02 , C07D307/20 , C07D413/06 , C07D493/04 , C07D493/22 , C07H7/02 , C07D405/06
CPC分类号： C07D307/20 , A61K31/366 , C07D405/06 , C07D413/06 , C07D493/04 , C07D493/22 , C07H7/02 , C07H9/02

4. 发明授权

EP2655353B9 DERIVATIVES OF GLYCO-CF2-SERINE AND GLYCO-CF2-THREONINE 有权
标题翻译： GLYCO-CF2-SERINDERIVATE UND GLYCO-CF2-THREONINDERIVATE
公开(公告)号：EP2655353B9
公开(公告)日：2015-08-05
申请号：EP11805036.8
申请日：2011-12-22
申请人： Tfchem
发明人： DELIENCOURT-GODEFROY, Géraldine , FILLON, Hyacinthe , MARTIN, Thibaut
IPC分类号： C07D309/10 , C07K9/00 , A61K38/14
CPC分类号： C07K9/001 , A01N1/0226 , A61K8/64 , A61Q19/08 , C07D309/10 , C07H7/02 , C07H7/04 , C07H15/18 , C07K1/063 , C07K5/0606 , C07K5/06191 , C07K5/081 , C07K5/0827 , C07K9/00

5. 发明公开

EP2797945A4 2-((2S,3S,4R,5R)-5-((S)-3-AMINO-2-HYDROXYPROP-1-YL)-4-METHOXY-3-(PHENYLSULFONYLMETHYL)TETRAHYDROFURAN-2-YL)ACETALDEHYDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION 失效
标题翻译： 2 - （（2S，3S，4R，5R）-5 - （（S）-3-氨基-2-羟基丙-1-基）-4-甲氧基-3-（PHENYLSULFONYLMETHYL-）四氢呋喃-2-基）乙醛衍生物及其制备方法
公开(公告)号：EP2797945A4
公开(公告)日：2015-06-03
申请号：EP12863099
申请日：2012-12-24
申请人： ALPHORA RES INC
发明人： SOUZA FABIO E S , RUDOLPH ALENA , PAN MING , GORIN BORIS , ALBERICO DINO
IPC分类号： C07H9/02 , C07D307/20 , C07D405/06 , C07D413/06 , C07D493/04 , C07D493/22 , C07H7/02
CPC分类号： C07D307/20 , A61K31/366 , C07D405/06 , C07D413/06 , C07D493/04 , C07D493/22 , C07H7/02 , C07H9/02

6. 发明公开

EP2862581A2 Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid 有权
标题翻译：递送3-氨基-1-丙磺酸的方法，化合物，组合物和媒介物
公开(公告)号：EP2862581A2
公开(公告)日：2015-04-22
申请号：EP14200552.9
申请日：2007-10-12
申请人： BHI Limited Partnership
发明人： The designation of the inventor has not yet been filed
IPC分类号： A61K47/48 , C07K5/06 , C07K5/08 , C07C309/15 , C07D207/16 , C07D209/20 , C07D217/24 , C07D233/64 , C07D291/02 , C07D333/24 , C12P11/00 , A61K38/07 , A61K38/08 , A61P25/28
CPC分类号： A61K31/145 , A61K47/54 , A61K47/542 , A61K47/545 , A61K47/549 , A61K47/554 , A61K47/64 , C07C309/15 , C07C309/18 , C07C309/19 , C07C309/24 , C07D207/16 , C07D209/20 , C07D217/24 , C07D233/64 , C07D285/36 , C07D285/38 , C07D291/02 , C07D323/02 , C07D333/24 , C07H7/02 , C07H15/12 , C07J9/005 , C07K5/06026 , C07K5/06052 , C07K5/0606 , C07K5/06069 , C07K5/06086 , C07K5/0806 , C07K5/081 , C12P11/00 , C12P13/001 , Y02P20/55
摘要： The invention relates to methods, compounds, compositions and vehicles for delivering 3-amino-1 -propanesulfonic acid (3APS) in a subject, preferably a human subject. The invention encompasses compounds that will yield or generate 3APS, either in vitro or in vivo. Preferred compounds include amino acid prodrugs of 3APS for use, including but not limited to, the prevention and treatment of Alzheimer's disease.
摘要翻译：本发明涉及用于在受试者，优选人受试者中递送3-氨基-1-丙磺酸（3APS）的方法，化合物，组合物和载体。本发明包括在体外或体内产生或产生3APS的化合物。优选的化合物包括使用3APS的氨基酸前药，包括但不限于预防和治疗阿尔茨海默病。

7. 发明授权

EP2089417B1 METHODS, COMPOUNDS, COMPOSITIONS AND VEHICLES FOR DELIVERING 3-AMINO-1-PROPANESULFONIC ACID 有权转让
标题翻译：方法，化合物，组合物及车辆的给药3-氨基-1-丙烷磺酸
公开(公告)号：EP2089417B1
公开(公告)日：2014-12-31
申请号：EP07875176.5
申请日：2007-10-12
申请人： BHI Limited Partnership
发明人： KONG, Xianqi , ATFANI, Mohamed , BACHAND, Benoit , BOUZIDE, Abderrahim , CIBLAT, Stephane , LEVESQUE, Sophie , MIGNEAULT, David , VALADE, Isabelle , WU, Xinfu , DELORME, Daniel
IPC分类号： C07K5/062 , C07K5/06 , C07K5/08 , C07C309/15 , C07D207/16 , C07D209/20 , C07D217/24 , C07D233/64 , C07D291/02 , C07D333/24 , C12P11/00 , A61K38/07 , A61K38/08 , A61P25/28 , C07K5/083 , C07K5/068
CPC分类号： A61K31/145 , A61K47/54 , A61K47/542 , A61K47/545 , A61K47/549 , A61K47/554 , A61K47/64 , C07C309/15 , C07C309/18 , C07C309/19 , C07C309/24 , C07D207/16 , C07D209/20 , C07D217/24 , C07D233/64 , C07D285/36 , C07D285/38 , C07D291/02 , C07D323/02 , C07D333/24 , C07H7/02 , C07H15/12 , C07J9/005 , C07K5/06026 , C07K5/06052 , C07K5/0606 , C07K5/06069 , C07K5/06086 , C07K5/0806 , C07K5/081 , C12P11/00 , C12P13/001 , Y02P20/55
摘要： The invention relates to methods, compounds, compositions and vehicles for delivering 3-amino-1 -propanesulfonic acid (3APS) in a subject, preferably a human subject. The invention encompasses compounds that will yield or generate 3APS, either in vitro or in vivo. Preferred compounds include amino acid prodrugs of 3APS for use, including but not limited to, the prevention and treatment of Alzheimer's disease.

8. 发明公开

EP2650289A1 Glycomimetics as pseudomonas Aeruginosa lectin inhibitors 有权转让
标题翻译： Glycomimetie als Pseudomonas aeruginosa-Hemmer
公开(公告)号：EP2650289A1
公开(公告)日：2013-10-16
申请号：EP12002531.7
申请日：2012-04-10
申请人： Universität Konstanz
发明人： Titz, Alexander, Dr.
IPC分类号： C07D309/10 , A61K31/351 , A61P31/04
CPC分类号： C07H15/04 , A61K31/351 , A61K31/7028 , A61K45/06 , C07D309/02 , C07D309/10 , C07D407/12 , C07H7/02 , C07H7/04 , C07H7/06
摘要： The present invention relates to fucose- and mannose-derived glycomimetics and their general use in prophylaxis or treatment of Pseudomonas aeruginosa infections including respiratory tract infections, urinary tract infections, nosocomial infections and chronic wound infections in a patient encompassing a patient suffering already from cystic fibrosis. Said glycomimetics are inhibitors of Pseudomonas aeruginosa lectin LecB.
摘要翻译：本发明涉及岩藻糖和甘露糖衍生的糖模拟物及其在包括患有囊性纤维化的患者的患者中预防或治疗铜绿假单胞菌感染的一般用途，包括呼吸道感染，尿路感染，医院感染和慢性伤口感染。所述糖模拟物是铜绿假单胞菌凝集素LecB的抑制剂。

9. 发明公开

EP2351763A1 METHOD FOR EXTRACTION OF COMPOUND CONTAINING SIALIC ACID FROM PLANT 审中-公开
标题翻译： VERFAHREN ZUR EXTRAKTION EINERSIALSÄUREHALTIGENVERBINDUNG AUS PFLANZEN
公开(公告)号：EP2351763A1
公开(公告)日：2011-08-03
申请号：EP10763575.7
申请日：2010-06-14
申请人： Incorporated Administrative Agency National Agriculture and Food Research Organization
发明人： Kawase, Shin-ichiro
IPC分类号： C07H7/027 , C07H1/08
CPC分类号： C07H1/08 , C07H7/02
摘要： An obj ect of the present invention is to provide an inexpensive and simple extraction method for a sialic acid-containing compound from a raw material which is easily available and has no risk of contamination with pathogens affecting animals (raw material which has high safety) without requiring the use of a reagent harmful to the human body and environment. The present invention is also aimed at providing an extraction method for a sialic acid-containing compound, the method comprising: crudely extracting a soluble component from a plant body (in particular, seeds of cereal and/or seeds of bean) or a processed product of the plant body with water, an alcohol, or an aqueous alcohol; and separating and recovering the sialic acid-containing compound from the resultant crude extract solution by dialysis, salt precipitation, or column chromatography.
摘要翻译：本发明的目的在于提供一种从容易获得的唾液酸化合物的廉价且简单的提取方法，并且不会有影响动物的病原体（具有高安全性的原料）没有污染的风险而没有要求使用对人体和环境有害的试剂。本发明的目的还在于提供含唾液酸化合物的提取方法，该方法包括：从植物体（特别是豆的谷类和/或种子的种子）或加工品中粗提取可溶性成分的植物体用水，酒精或含水酒精; 并通过透析，盐析或柱色谱从所得粗提液中分离回收唾液酸化合物。

10. 发明授权

EP2084172B1 NEUE MIT BENZYLRESTEN SUBSTITUIERTE 1,4-BENZOTHIEPIN-1,1-DIOXIDDERIVATE, VERFAHREN ZU DEREN HERSTELLUNG, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL UND DEREN VERWENDUNG 有权
标题翻译： NEW用苄基取代的1,4-苯并硫-1,1-二氧化物的衍生物，用于生产药物含有它们及其用途
公开(公告)号：EP2084172B1
公开(公告)日：2010-12-22
申请号：EP07819434.7
申请日：2007-10-30
申请人： Sanofi-Aventis Deutschland GmbH
发明人： FRICK, Wendelin , GLOMBIK, Heiner , THEIS, Stefan , HEUER, Hubert , SCHAEFER, Hans-Ludwig , KRAMER, Werner
IPC分类号： C07H5/06 , A61K31/7028
CPC分类号： C07H5/06 , A61K31/38 , A61K31/7028 , A61K45/06 , C07D409/12 , C07H5/04 , C07H7/02 , C07H7/027 , C07H13/12 , C07H15/26 , A61K2300/00
摘要： The invention relates to the compounds of formula (I) and to the physiologically acceptable salts thereof. These compounds are suitable, for example, as hypolipidemics.

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