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1. 发明公开

EP3129359A1 DIAMINOTRIAZINE DERIVATIVES AS HERBICIDES 有权
标题翻译：作为除草剂的二氨基三嗪衍生物
公开(公告)号：EP3129359A1
公开(公告)日：2017-02-15
申请号：EP15716017.7
申请日：2015-04-09
申请人： BASF SE
发明人： MAJOR, Julia , VOGT, Florian , CALO, Frederick , SEITZ, Thomas , SCHACHTSCHABEL, Doreen , NEWTON, Trevor William , HANZLIK, Kristin , HUTZLER, Johannes , KREUZ, Klaus , TRESCH, Stefan
IPC分类号： C07D251/48 , A01N43/68 , A01P13/00
CPC分类号： C07D251/18 , A01N43/68 , C07D251/48
摘要： The present invention relates to diaminotriazine compounds of the formula (I) and to their use as herbicides. The present invention also relates to agrochemical compositions for crop protection and to a method for controlling unwanted vegetation.
摘要翻译：本发明涉及式（I）的二氨基三嗪化合物及其作为除草剂的用途。本发明还涉及用于保护作物的农业化学组合物和控制不想要的植物的方法。

2. 发明授权

EP2595965B1 INSECTICIDAL TRIAZINES AND PYRIMIDINES 失效
标题翻译：三嗪和嘧啶，其杀虫剂
公开(公告)号：EP2595965B1
公开(公告)日：2016-06-22
申请号：EP11743699.8
申请日：2011-07-20
申请人： Vestaron Corporation
发明人： KENNEDY, Robert, M. , STEINBAUGH, Bruce, A.
IPC分类号： C07D403/12 , A01N43/54 , A01N43/68 , A01N43/84 , C07D405/12 , C07D239/49 , C07D409/12 , C07D239/48 , C07D401/12 , C07D413/12 , C07D251/48
CPC分类号： C07D239/49 , A01N43/54 , A01N43/68 , A01N43/84 , C07D239/48 , C07D251/48 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12

3. 发明公开

EP3031803A1 BENZOGUANAMINE COMPOUND HAVING AMINOMETHYL GROUP OR SALT THEREOF, AND METHOD FOR MANUFACTURING SAME 有权
标题翻译：与氨或其盐和方法及其生产苯代三聚氰胺
公开(公告)号：EP3031803A1
公开(公告)日：2016-06-15
申请号：EP14834522.6
申请日：2014-07-08
申请人： Mitsubishi Gas Chemical Company, Inc.
发明人： KANBARA, Yutaka , TSUJIMOTO, Tomoo
IPC分类号： C07D251/18 , C07B61/00
CPC分类号： C07D251/48 , C07D251/18
摘要： A benzoguanamine compound having an amino methyl group is represented by the following Formula (1), or a salt thereof:

wherein R represents a substituent selected from the group consisting of hydrogen, an alkyl group having 1 to 10 carbon atoms, an alkoxy group having 1 to 10 carbon atoms, an aryl group having 6 to 10 carbon atoms, an aryloxy group having 6 to 10 carbon atoms, a hydroxyl group, an amide group, and a halogen atom, and n is an integer of 1 to 2.
摘要翻译：具有氨基甲基苯并胍胺化合物是由以下通式（1），或它们的盐表示：氢worinřdarstellt选自对具有1至10个碳原子烷基的取代基，以烷氧基具有具有6至10个碳原子的芳基具有1-10个碳原子，芳氧基，以具有6至10个碳原子，羟基基团为酰胺基团，和卤原子基团，并且n为1到第二整数

4. 发明公开

EP2533782A1 PIPERAZINE DERIVATIVES FOR BLOCKING Cav2.2 CALCIUM CHANNELS 有权
标题翻译：哌嗪用于锁定Cav2.2钙通道
公开(公告)号：EP2533782A1
公开(公告)日：2012-12-19
申请号：EP11700576.9
申请日：2011-01-14
申请人： Convergence Pharmaceuticals Limited
发明人： HEER, Jag Paul , CRIDLAND, Andrew Peter , NORTON, David
IPC分类号： A61K31/496 , C07D217/26 , C07D251/48 , C07D401/06 , A61P25/02 , A61P29/00
CPC分类号： C07D401/06 , A61K31/496 , C07D215/48 , C07D217/26 , C07D251/48
摘要： The present invention relates to novel piperazine compounds; to pharmaceutical compositions containing the compounds; and to the use of the compounds in therapy to treat diseases for which blocking the Ca
v 2.2 calcium channels is beneficial and to treat diseases for which blocking the Ca
v 2.2 and Ca
v 3.2 calcium channels is beneficial, e.g. to treat pain.

7. 发明公开

EP1885486A1 AFFINITY ADSORBENTS FOR FACTOR VIII AND VON WILLEBRAND'S FACTOR 有权转让
标题翻译：亲和吸附剂因子VIII和血管性血友病因子
公开(公告)号：EP1885486A1
公开(公告)日：2008-02-13
申请号：EP06727055.3
申请日：2006-05-09
申请人： Prometic Biosciences Ltd
发明人： BETLEY, Jason, Richard , BAINES, Baldev, Singh ProMetic BioSciences Ltd.
IPC分类号： B01J20/32 , G01N30/00 , G01N33/86 , C07D251/48 , C07D251/50 , C07D251/70
CPC分类号： B01J20/286 , B01J20/289 , B01J20/3212 , B01J20/3219 , B01J20/3242 , B01J20/3244 , B01J20/3251 , B01J20/3253 , B01J20/3255 , B01J2220/54 , B01J2220/58 , C07D251/48 , C07D251/50 , C07D251/70 , C07D403/12 , C07K14/755 , G01N33/86 , G01N2333/755 , Y10T436/25375 , Y10T436/255
摘要： For the separation, removal, isolation, purification, characterization, identification or quantification of Factor VIII, von Willebrand's Factor or a protein that is a analogue of either, an affinity adsorbent is used that is a compound of formula (II) wherein one X is N and the other is N, C—Cl or C—CN; A is a support matrix, optionally linked to the triazine ring by a spacer; Y is O, S or NR2; Z is O, S or N—R3; R2 and R3 are each H, C1-6 alkyl, C1-6 hydroxyalkyl, benzyl or &bgr;-phenylethyl; B and W are each an optionally substituted hydrocarbon linkage containing from 1 to 10 carbon atoms; D is H, OH or a primary amino, secondary amino, tertiary amino, quaternary ammonium, imidazole, guanidino or amidino group; or B-D is —CHCOOH—(CH2)3-4—NH2; and R7 is a group bearing a positive charge at neutral pH.

8. 发明公开

EP1436266A4 METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS 审中-公开
标题翻译：方法和组合物新三嗪
公开(公告)号：EP1436266A4
公开(公告)日：2004-12-22
申请号：EP02799019
申请日：2002-09-23
申请人： REDDY US THERAPEUTICS INC
发明人： TIMMER RICHARD T , ALEXANDER CHRISTOPHER W , PILLARISETTI SIVARAM , SAXENA UDAY , CAMPBELL KAREN A
IPC分类号： A61K31/35 , A61K31/53 , A61K31/5377 , A61P19/02 , A61P29/00 , A61P35/00 , A61P43/00 , C07D251/44 , C07D251/46 , C07D251/48 , C07D251/50 , C07D251/52 , C07D251/70 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D403/14 , C07D405/12 , C07D405/14 , C07D409/14 , C07D453/02 , C07D471/08 , A61P17/06
CPC分类号： C07D401/12 , C07D251/44 , C07D251/46 , C07D251/48 , C07D251/50 , C07D251/52 , C07D251/70 , C07D403/04 , C07D403/12 , C07D403/14 , C07D453/02
摘要： The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.

9. 发明公开

EP1436266A2 METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS 审中-公开
标题翻译：新型三嗪化合物的方法和组合物
公开(公告)号：EP1436266A2
公开(公告)日：2004-07-14
申请号：EP02799019.1
申请日：2002-09-23
申请人： Reddy US Therapeutics, Inc.
发明人： TIMMER, Richard, T. , ALEXANDER, Christopher, W. , PILLARISETTI, Sivaram , SAXENA, Uday , CAMPBELL, Karen, A.
IPC分类号： C07D251/44
CPC分类号： C07D401/12 , C07D251/44 , C07D251/46 , C07D251/48 , C07D251/50 , C07D251/52 , C07D251/70 , C07D403/04 , C07D403/12 , C07D403/14 , C07D453/02
摘要： The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
摘要翻译：本发明涉及包含治疗由炎症反应引起的病理生理状况的化合物的方法和组合物。具体而言，本发明涉及抑制或阻断糖化蛋白质诱导内皮细胞中信号相关炎症反应的化合物。本发明涉及抑制平滑肌增殖的化合物。具体而言，本发明涉及通过调节HSPG例如Perlecan来抑制平滑肌细胞增殖的化合物。本发明进一步涉及化合物用于治疗以平滑肌增殖为特征的血管阻塞性病症如再狭窄和动脉粥样硬化的用途。

10. 发明公开

EP1293504A2 Triazinderivate als UV-Filter in kosmetischen Mitteln 失效
公开(公告)号：EP1293504A2
公开(公告)日：2003-03-19
申请号：EP02025811.7
申请日：1997-07-02
申请人： Ciba Specialty Chemicals Holding Inc.
发明人： Metzger, Georges , Reinehr, Dieter , Luther, Helmut
IPC分类号： C07D251/70 , A61K7/42
CPC分类号： C07D251/52 , A61K8/4966 , A61K8/4993 , A61Q17/04 , C07D251/48 , C07D251/50 , C07D251/70
摘要： Die vorliegende Erfindung betrifft die nichttherapeutische Verwendung von s-Triazinverbindungen der Formel
worin

R einen Rest der Formel (1a)

X 1 , X 2 und X 3 -SO 2 R 4 ;

R 4 verzweigtes oder geradkettiges C 1 -C 22 -Alkyl; C 5 -C 8 -Cycloalkyl; gegebenenfalls mit einem oder mehreren C 1 -C 4 -Alkyl substituiertes C 6 -C 12 -Aryl; gegebenenfalls mit einem oder mehreren C 1 -C 4 -Alkyl substituiertes C 7 -C 10 -Aralkyl; einen Rest der Formel (1b); oder

R 2 und R 3 unabhängig voneinander Wasserstoff; geradkettiges oder verzweigtes C 1 -C 22 -Alkyl; C 5 -C 8 -Cycloalkyl; gegebenenfalls mit einem oder mehreren C 1 -C 4 -Alkyl substituiertes C 6 -C 12 -Aryl; gegebenenfalls mit einem oder mehreren C 1 -C 4 -Alkyl substituiertes C 7 -C 10 -Aralkyl; einen Rest der Formel (1b)
worin
A 1 geradkettiges oder verzweigtes C 1 -C 8 -Alkyl; C 5 -C 8 -Cycloalkyl; gegebenenfalls mit einem oder mehreren C 1 -C 4 -Alkyl substituiertes C 6 -C 12 -Aryl; oder gegebenenfalls mit einem oder mehreren C 1 -C 4 -Alkyl substituiertes C 7 -C 10 -Aralkyl;
m 1 1 bis 10; und
X 4 , X 5 und X 6 Wasserstoff; oder Hxdroxy;
bedeuten, als UV-Filter in Sonnenschutzmitteln.
摘要翻译：化妆品制剂包含至少一种三嗪化合物和赋形剂或添加剂。化妆品制剂（I）包含至少一种式（1）的三嗪化合物和赋形剂或添加剂。 R =式（1a）; X1，X2，X3 = -SO2R4; R4 = 1-22C烷基，5-8C环烷基，6-12C芳基，任选被1-4C烷基取代，7-10C芳烷基，任选被1-4C烷基或-N（R2）（R3）取代; R2，R3 = 1-22C烷基，5-8C环烷基，任选被1-4C烷基取代的6-12C芳基，任选被1-4C烷基或 - （亚烷基-O-）m-A1取代的7-10C芳烷基 ; A1 = 1-8C烷基，5-8C环烷基，任选被1-4C烷基取代的6-12C芳基，任选被1-4C烷基取代的7-10C芳烷基; m = 1-10; X4，X5，X6 = H或羟基。

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