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1. 发明授权

EP3087919B1 RECEIVING FLUIDS 有权转让
公开(公告)号：EP3087919B1
公开(公告)日：2018-09-26
申请号：EP16162360.8
申请日：2012-04-26
申请人： Seventh Sense Biosystems, Inc.
发明人： Gonzalez-Zugasti, Javier , Boccuti, A. David , Chickering III, Donald., E. , Michelman, Mark , Haghgooie, Ramin , Davis, Shawn , James, Scott , Dadgar, Maisam , Fisher, Greg , Miller, Richard, L. , Morse, Christopher, J.
IPC分类号： G16H10/40 , A61B5/00 , A61B10/00 , A61B5/145 , A61B5/1459 , A61B5/1486 , A61B5/15 , A61B5/151 , A61M37/00
CPC分类号： A61B5/150374 , A61B5/1411 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/1459 , A61B5/14865 , A61B5/150022 , A61B5/150099 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150755 , A61B5/150969 , A61B5/150977 , A61B5/150984 , A61B5/151 , A61B5/15113 , A61B5/15117 , A61B5/15144 , A61B5/154 , A61B5/411 , A61B5/685 , A61B10/0045 , A61B10/0051 , A61B10/007 , A61B2010/008 , A61M37/0015 , G06F19/00 , G16H10/40
摘要： The present application generally relates to receiving bodily fluid through a device opening (130).The device includes a flow activator (90) arranged to cause fluid to be released from a subject. A deployment actuator (60) actuates the flow activator in a deployment direction, which in turn causes fluid release from a subject. The flow activator is also moved in a retraction direction by a retraction actuator (40).

2. 发明公开

EP3257442A2 RELATIVELY SMALL DEVICES APPLIED TO THE SKIN, MODULAR SYSTEMS, AND METHODS OF USE THEREOF 审中-公开
公开(公告)号：EP3257442A2
公开(公告)日：2017-12-20
申请号：EP17180578.1
申请日：2010-10-29
申请人： Seventh Sense Biosystems, Inc.
发明人： Bernstein, Howard , Chickering, Donald E., III , Levinson, Douglas A. , Walt, David R. , Davis, Shawn , Haghgooie, Ramin
IPC分类号： A61B5/151
CPC分类号： A61B5/14514 , A61B5/150022 , A61B5/150099 , A61B5/150221 , A61B5/150229 , A61B5/150297 , A61B5/150305 , A61B5/150389 , A61B5/150412 , A61B5/150503 , A61B5/150755 , A61B5/150969 , A61B5/150977 , A61B5/150984 , A61B5/15105 , A61B5/15109 , A61B5/15113 , A61B5/15117 , A61B5/15125 , A61B5/15144 , A61B5/15186 , A61B5/157 , A61B5/685 , A61B2560/0412 , A61B2560/0443 , A61M5/425 , A61M35/00 , A61M37/0015 , A61M2037/0023 , A61M2037/003 , A61M2037/0046 , A61M2037/0061 , A61M2205/581 , A61M2205/582 , A61M2205/583 , A61M2205/588
摘要： The present invention generally relates, in certain aspects, to relatively small devices applied to the skin, modular systems, and methods of use thereof. In some aspects, the device is constructed and arranged to have more than one module. For instance, the device may have a module for delivering to and/or withdrawing fluid from the skin and/or beneath the skin of a subject and a module for transmitting a signal indicative of the fluid delivered to and/or withdrawn from the skin and/or beneath the skin of the subject, a module for analyzing a fluid withdrawn from the skin and/or beneath the skin of the subject, or the like. In some embodiments, the modules are connectable and/or detachable from each other, and in some cases, the connections and/or detachments may be performed while the device is in contact with the subject, e.g., while affixed to the subject. In some embodiments, the device may be repeatedly applicable to the skin of the subject to deliver to and/or withdraw fluid from the skin and/or beneath the skin of a subject, e.g., at the same location, or at different locations on the skin of the subject. In some aspects, the devices may be self-contained and/or have a relatively small size, and in some cases, the device may be sized such that it is wearable and/or able to be carried by a subject. For example, the device may have a mass and/or dimensions that allow the device to be carried or worn by a subject for various periods of time, e.g., at least about an hour, at least about a day, at least about a week, etc., or no more than about an hour, no more than about 10 min, etc.

3. 发明公开

EP3045112A1 BODILY FLUID COLLECTION DEVICE AND TESTING DEVICE 有权
标题翻译：试验台上的KÖRPERFLÜSSIGKEITSENTNAHMEVORRICHTUNG
公开(公告)号：EP3045112A1
公开(公告)日：2016-07-20
申请号：EP14843377.4
申请日：2014-09-05
申请人： Sosaikouseikai Clinical Foundation Matsunami Research Park
发明人： MATSUNAMI, Hidetoshi , SAITO, Kuniaki , MATUO, Yush , TAKEMURA, Masao
IPC分类号： A61B5/151 , A61B5/00
CPC分类号： A61B5/150732 , A61B5/150022 , A61B5/150099 , A61B5/150389 , A61B5/150572 , A61B5/150748 , A61B5/150969 , A61B5/150977 , A61B5/15105 , A61B5/15142 , A61B5/157
摘要： A testing device according to the present invention includes a housing including a skin surface sheet and an upper surface cover. A hollow needle configured to interlock with the upper surface cover and testing means are accommodated in the housing. Through deformation of the upper surface cover by application of an external force, the hollow needle perforates the skin. A body fluid flows in the space inside of the housing and is brought into contact with the testing means to acquire information on the body fluid. Through recovery of the upper surface cover to an original shape by elimination of the external force, the hollow needle again becomes accommodated in the housing.
摘要翻译：根据本发明的测试装置包括壳体，其包括皮肤表面片和上表面盖。构造成与上表面盖和测试装置互锁的中空针容纳在壳体中。通过施加外力使上表面罩变形，中空针穿透皮肤。体液在壳体内的空间中流动并与测试装置接触以获取关于体液的信息。通过消除外力，通过将上表面盖恢复成原始形状，中空针再次容纳在壳体中。

4. 发明公开

EP2523706A2 RAPID DELIVERY AND/OR WITHDRAWAL OF FLUIDS 有权转让
标题翻译： SCHNELLE AUSGABE UND / ODER ENTNAHME VONFLÜSSIGKEITEN
公开(公告)号：EP2523706A2
公开(公告)日：2012-11-21
申请号：EP11700881.3
申请日：2011-01-13
申请人： Seventh Sense Biosystems, Inc.
发明人： CHICKERING, Donald, E. ,III , DAVIS, Shawn , HAGHGOOIE, Ramin , BERNSTEIN, Howard , LEVINSON, Douglas, A. , MICHELMAN, Mark
IPC分类号： A61M5/178 , A61B5/151 , A61B5/145
CPC分类号： A61B5/6849 , A61B5/14532 , A61B5/150022 , A61B5/150099 , A61B5/150221 , A61B5/150229 , A61B5/150297 , A61B5/150389 , A61B5/150412 , A61B5/150503 , A61B5/150755 , A61B5/150969 , A61B5/150977 , A61B5/150984 , A61B5/15105 , A61B5/15113 , A61B5/15117 , A61B5/15125 , A61B5/15144 , A61B5/15186 , A61B5/157 , A61B5/685
摘要： The present invention generally relates to systems and methods for delivering and/or withdrawing a substance or substances such as blood or interstitial fluid, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for withdrawing or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to withdraw blood from the subject. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. For example, blood may be withdrawn from the device, and/or the device may contain sensors or agents able to determine the blood and/or an analyte suspected of being contained in the blood. Other aspects of the present invention are directed at other devices for withdrawing blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like.
摘要翻译：本发明总体上涉及用于递送和/或从皮肤和/或皮肤下面的受试者递送和/或取出物质或诸如血液或间质液的物质的方法。在一个方面，本发明一般涉及使用包含流体转运器（例如，一个或多个微针）的装置从皮肤和/或从皮肤下方抽取或提取血液的装置和方法）和在接收血液之前具有小于大气压的内部压力的储存室。在一些情况下，该装置可以是独立的，并且在某些情况下，可以将该装置应用于皮肤并被激活以从受试者中抽出血液。然后可以处理装置或其一部分，以单独或与外部装置一起确定血液和/或血液中的分析物。例如，血液可以从装置中取出，和/或装置可以包含能够确定血液和/或怀疑包含在血液中的分析物的传感器或试剂。本发明的其它方面涉及用于抽出血液（或其它体液，例如间质液）的其他装置，涉及这种装置的试剂盒，制造这种装置的方法，使用这种装置的方法等。

5. 发明公开

EP2182849A4 LANCET SYSTEM 有权
标题翻译：柳叶刀系统
公开(公告)号：EP2182849A4
公开(公告)日：2010-09-15
申请号：EP08782146
申请日：2008-07-21
申请人： KIM STANLEY
发明人： KIM STANLEY
IPC分类号： A61B5/15 , A61B5/151 , A61B17/34
CPC分类号： A61B5/150969 , A61B5/1411 , A61B5/150022 , A61B5/150152 , A61B5/150198 , A61B5/150396 , A61B5/150412 , A61B5/150427 , A61B5/150519 , A61B5/150549 , A61B5/150587 , A61B5/150603 , A61B5/150618 , A61B5/150717 , A61B5/150916 , A61B5/150938 , A61B5/150977 , A61B5/15113 , A61B5/15117 , A61B5/15142 , A61B5/1519 , A61B5/15194

6. 发明公开

EP1862116A2 Disposable element for use in a body fluid sampling device 失效
标题翻译：一种用于在装置中使用的一次性元件，用于采集体液样品
公开(公告)号：EP1862116A2
公开(公告)日：2007-12-05
申请号：EP07113978.6
申请日：1997-05-16
申请人： Roche Diagnostics Operations, Inc.
发明人： Douglas, Joel S. , Roe, Jeffrey N. , Radwanski, Ryszard , Duchon, Brent G. , Sanchez, Michael J. , Grage, Henry M.
IPC分类号： A61B5/145 , A61B10/00 , A61B17/32
CPC分类号： B82Y30/00 , A61B5/14532 , A61B5/150022 , A61B5/150068 , A61B5/150343 , A61B5/150419 , A61B5/150427 , A61B5/150519 , A61B5/150824 , A61B5/150977 , A61B5/15111 , A61B5/15117 , A61B5/15194 , A61B10/0045 , A61B2010/008 , A61B2017/00765 , A61B2562/0295
摘要： A disposable lancing element (12) is adapted for use in a lancing device (10) for making an incision through a user's skin. The lancing element (12) includes a body (16) which defines a longitudinal axis, and has a skin lancing member projecting from a front end thereof. A capillary tube (18) is mounted in the body in laterally spaced relationship to the skin lancing member, and is slidable longitudinally relative to the body (16) so as to be extended forwardly past the skin lancing member. The body (16) includes a plurality of circumferentially spaced, radially outwardly projecting bosses (31) formed thereon for guiding the disposable element installation in a carrier element. The kin lancing member may comprise a plurality of needles (14) or barbs arranged in parallel side by side relationship. In lieu of a skin lancing member, the disposable element (12) may possess a longitudinal through hole for conducting a skin piercing laser light beam or pressurized fluid. A capillary tube (18) may have an outwardly flared lower (inlet) end. A capillary tube (18) may possess a sensor for sensing a level of fluid rising therein.
摘要翻译：甲一次性采血元件（12）是angepasst用于在穿刺装置（10），用于通过使用者的皮肤使在切口的使用。穿刺元件（12）包括主体（16），其限定了纵向轴线，且具有皮肤刺血构件从其前端伸出。甲毛细管（18）被安装在主体中尾盘反弹间隔关系到皮肤刺血构件和可滑动沿纵向相对于所述主体（16），以便被过去的皮肤刺血构件向前延伸。所述主体（16）包括用于在载体元件引导一次性元件安装在其上形成沿周向隔开，径向向外突出的凸台（31）的复数。的亲属刺血构件可包括由并列关系在平行并排布置的针（14）或倒钩的复数。代替皮肤穿刺体的，一次性元件（12）可以通过用于进行皮肤穿刺激光光线或加压流体孔纵向具有一个。甲毛细管（18）可以具有在向外张开的下部（入口）端。甲毛细管（18）可以具有一个传感器，用于感测流体在其中上升的电平。

7. 发明公开

EP0797951A4 BLOOD SPECIMEN COLLECTOR 失效
标题翻译：设备验收血样
公开(公告)号：EP0797951A4
公开(公告)日：1999-11-17
申请号：EP96914398
申请日：1996-05-22
申请人： ADVANCE KK
发明人： SESEKURA TETSUYA
IPC分类号： A61B5/154 , A61B5/145 , A61B5/15 , A61B5/14
CPC分类号： A61B5/150977 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150114 , A61B5/150412 , A61B5/150519 , A61B5/15113 , A61B5/15125 , A61B5/15194
摘要： A blood specimen collector provided with means for sucking the skin by depressurization, puncturing means for abutting a puncturing member (2) against the skin thus sucked, and releasing means (13) for pulling out the abutted member (2) from the skin; and another blood specimen collector provided with puncturing means having a multi-needle structure.

8. 发明授权

EP3045112B1 BODILY FLUID COLLECTION DEVICE AND TESTING DEVICE 有权
标题翻译：液体收集装置和测试装置
公开(公告)号：EP3045112B1
公开(公告)日：2018-01-17
申请号：EP14843377.4
申请日：2014-09-05
申请人： Sosaikouseikai Clinical Foundation Matsunami Research Park
发明人： MATSUNAMI, Hidetoshi , SAITO, Kuniaki , MATUO, Yushi , TAKEMURA, Masao
IPC分类号： A61B5/151 , A61B5/00 , A61B5/15 , A61B5/157
CPC分类号： A61B5/150732 , A61B5/150022 , A61B5/150099 , A61B5/150389 , A61B5/150572 , A61B5/150748 , A61B5/150969 , A61B5/150977 , A61B5/15105 , A61B5/15142 , A61B5/157
摘要： A testing device according to the present invention includes a housing including a skin surface sheet and an upper surface cover. A hollow needle configured to interlock with the upper surface cover and testing means are accommodated in the housing. Through deformation of the upper surface cover by application of an external force, the hollow needle perforates the skin. A body fluid flows in the space inside of the housing and is brought into contact with the testing means to acquire information on the body fluid. Through recovery of the upper surface cover to an original shape by elimination of the external force, the hollow needle again becomes accommodated in the housing.

9. 发明公开

EP3243435A1 SAMPLING DEVICE INTERFACES 审中-公开
标题翻译：采样设备接口
公开(公告)号：EP3243435A1
公开(公告)日：2017-11-15
申请号：EP17168976.3
申请日：2011-01-13
申请人： Seventh Sense Biosystems, Inc.
发明人： Chickering, Donald, E. , Davis, Shawn , Haghgooie, Ramin , Bernstein, Howard , Levinson, Douglas, A.
IPC分类号： A61B5/151
CPC分类号： A61B5/14532 , A61B5/150022 , A61B5/150099 , A61B5/150221 , A61B5/150229 , A61B5/150236 , A61B5/150244 , A61B5/150297 , A61B5/150389 , A61B5/150412 , A61B5/150503 , A61B5/150755 , A61B5/150969 , A61B5/150977 , A61B5/150984 , A61B5/15105 , A61B5/15113 , A61B5/15117 , A61B5/15125 , A61B5/15144 , A61B5/15186 , A61B5/157 , A61B5/685
摘要： The present invention generally relates to systems and methods for delivering and/or withdrawing a substance or substances such as blood or interstitial fluid, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for withdrawing or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to withdraw blood from the subject. The device, in some cases, may be interfaced with external equipment to determine an analyte contained within a fluid contained within or collected by the device. For example, the device may be mounted or engaged on an external holder, the device may include a port for transporting fluid out of the device, the device may include a window for interrogating a fluid contained within the device, or the like. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. For example, blood may be withdrawn from the device, and/or the device may contain sensors or agents able to determine the blood and/or an analyte suspected of being contained in the blood. Other aspects of the present invention are directed at other devices for withdrawing blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like.
摘要翻译：本发明总体上涉及用于从受试者（例如从皮肤和/或从皮肤下方）输送和/或排出一种或多种物质（例如血液或间质液）的系统和方法。在一个方面，本发明总体上涉及用于使用含有液体转运体的装置（例如，一个或多个微针）从受试者（例如从皮肤和/或皮肤下面）抽取或抽取血液的装置和方法）以及在接收血液之前具有小于大气压的内部压力的储存室。在一些情况下，该装置可以是独立的，并且在某些情况下，该装置可以被施加到皮肤上，并被激活以从受试者中抽取血液。该装置在某些情况下可以与外部设备连接以确定装置内包含的或被装置收集的流体内包含的分析物。例如，该装置可以被安装或接合在外部保持器上，该装置可以包括用于将流体输送出装置的端口，该装置可以包括用于询问容纳在装置内的流体的窗口等。然后可以处理装置或其一部分，以单独地或利用外部装置来确定血液和/或血液内的分析物。例如，血液可以从装置中取出，和/或装置可以包含能够确定血液和/或怀疑包含在血液中的分析物的传感器或试剂。本发明的其它方面针对用于抽取血液（或其他体液，例如间质液）的其他装置，涉及这种装置的套件，制造这种装置的方法，使用这些装置的方法等。

10. 发明授权

EP2182849B1 LANCET SYSTEM 有权
标题翻译：柳叶刀系统
公开(公告)号：EP2182849B1
公开(公告)日：2013-06-05
申请号：EP08782146.8
申请日：2008-07-21
申请人： Kim, Stanley
发明人： Kim, Stanley
IPC分类号： A61B5/15 , A61B17/34 , A61B5/151
CPC分类号： A61B5/150969 , A61B5/1411 , A61B5/150022 , A61B5/150152 , A61B5/150198 , A61B5/150396 , A61B5/150412 , A61B5/150427 , A61B5/150519 , A61B5/150549 , A61B5/150587 , A61B5/150603 , A61B5/150618 , A61B5/150717 , A61B5/150916 , A61B5/150938 , A61B5/150977 , A61B5/15113 , A61B5/15117 , A61B5/15142 , A61B5/1519 , A61B5/15194

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