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1. 发明授权

EP2085779B1 METER 有权
公开(公告)号：EP2085779B1
公开(公告)日：2017-11-01
申请号：EP09005912.2
申请日：1998-12-21
申请人： Roche Diagnostics Operations, Inc.
发明人： Beaty, Terry , Burke, David W. , Kuhn, Lance Scott , Svetnik, Vladimir
IPC分类号： G01N33/487
CPC分类号： G01N27/3274

2. 发明授权

EP2270481B1 Glucose measuring instrument 有权
标题翻译：血糖仪
公开(公告)号：EP2270481B1
公开(公告)日：2014-05-07
申请号：EP10011398.4
申请日：1998-12-04
申请人： Roche Diagnostics Operations, Inc.
发明人： Batman, Carol Jane , Carpenter, Greg Paul , Davies, Robert Glenn , KASLE, Richard J.
IPC分类号： G01N27/00 , G01N33/487
CPC分类号： H01M2/1055 , G01N33/48785 , H01M2/1022 , H01M2/20 , H01M10/425 , H01R13/24

3. 发明授权

EP2160981B1 Apparatus for expressing body fluid from an incision 失效
标题翻译：一种用于体液的排出设备
公开(公告)号：EP2160981B1
公开(公告)日：2013-04-10
申请号：EP09176754.1
申请日：1997-05-16
申请人： Roche Diagnostics Operations, Inc.
发明人： Douglas, Joel S , Roe, Jeffrey N , Grage, Henry M
IPC分类号： A61B17/32 , A61B5/151
CPC分类号： A61B5/15194 , A61B5/14532 , A61B5/150022 , A61B5/150068 , A61B5/150076 , A61B5/150083 , A61B5/150114 , A61B5/150122 , A61B5/150137 , A61B5/150412 , A61B5/15109 , A61B5/15113 , A61B5/15117 , A61B5/15186 , A61B10/0045 , A61B2010/008 , A61B2017/00765 , A61B2562/0295

4. 发明公开

EP2329421A1 USER INTERFACE FOR MANIPULATING GROUPS OF DATA REPRESENTATIONS OF A GRAPHICAL DISPLAY 有权转让
标题翻译：用户界面操纵图形显示的数据表示组
公开(公告)号：EP2329421A1
公开(公告)日：2011-06-08
申请号：EP09782587.1
申请日：2009-09-04
申请人： Roche Diagnostics Operations, Inc. , Roche Diagnostics GmbH , F. Hoffmann-La Roche AG
发明人： BUCK, Schuyler , BUSH, Jason , GREENBURG,Alan , MARKISOHN, David, Bradley , ORGAN, Leon, R., III
IPC分类号： G06F19/00
CPC分类号： G06F19/3468 , A61M5/14244 , G16H15/00
摘要： A system is disclosed wherein a graphical representation of a profile may be adjusted to adjust one or more values of the profile. The profile may includes data values corresponding to respective time periods. The data values being represented by data representations in the graphical representation. A non-contiguous grouping of the data representations may be selected by an operator to adjust the data values of the profile corresponding to the non-contiguous grouping of data representations. A contiguous grouping of the data representations may be selected by an operator to adjust the data values of the profile corresponding to the non-contiguous grouping of data representations.

5. 发明公开

EP2290362A2 Synchronized analyte testing system 失效
标题翻译：同步分析系统
公开(公告)号：EP2290362A2
公开(公告)日：2011-03-02
申请号：EP10176792.9
申请日：1997-10-30
申请人： Roche Diagnostics Operations, Inc.
发明人： Douglas, Joel S. , Drexler, Karen R. , Roe, Jeffrey N.
IPC分类号： G01N33/52
CPC分类号： G01N33/528 , A61B5/14532 , A61B5/1455 , A61B5/1495 , A61B5/150022 , A61B5/150259 , A61B5/150305 , A61B5/150343 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/15186 , A61B5/157 , A61B5/415 , A61B2560/0431 , A61B2562/0295 , A61B2562/085 , C12Q1/54 , G01D3/022 , G01N21/8483 , G01N33/48757 , G01N33/48771 , G01N33/525 , G01N33/66 , G01N2035/00138 , Y10S435/808 , Y10S435/817
摘要： An analyte detection system is provided with calibration information uniquely specific to the set of test strips to which the sample is to be applied. The calibration information may be stored in permanent memory of the testing device, such that the device is discarded after use of all the test strips in a kit, or it may be stored in a calibration chip accompanying the set of test strips and distributed therewith, thereby enabling re-use of the testing device with a different set of test strips and associated calibration chip.
摘要翻译：分析物检测系统具有唯一专用于待应用样品的测试条的校准信息。校准信息可以存储在测试装置的永久存储器中，使得在使用试剂盒中的所有测试条之后丢弃该装置，或者可将其存储在伴随该组测试条的校准芯片中并与其一起分布，从而能够利用不同的测试条和相关联的校准芯片来重新使用测试装置。

6. 发明授权

EP1082453B1 LIQUID REAGENT SET FOR L-LACTATE DETERMINATION 有权
标题翻译：液体试剂组L-LACTAT的测定
公开(公告)号：EP1082453B1
公开(公告)日：2008-12-24
申请号：EP99953363.1
申请日：1999-05-28
申请人： Roche Diagnostics Operations, Inc.
发明人： DORN, Allan, R. , HURT, Catherine, J. , MOUNTAIN, Larry, D. , SIEDEL, Joachim
IPC分类号： C12Q1/26 , C12Q1/28
CPC分类号： C12Q1/28 , C12Q1/26 , C12Q2326/00 , G01N2333/904 , G06F2207/7219 , Y10S435/962 , Y10S435/963 , Y10S435/975
摘要： The invention provides sets of liquid reagents that afford calibration stability in an enzyme based spectrophotometric assay for the measurement of lactate in patient samples. The reagent sets include a lactate oxidase, a peroxidase, a hydrogen donor, an agent that substantially prevents ascorbic acid interference, and agent that substantially prevents bilirubin interference, a coupling agent, a buffer and, optionally, a preservative. The invention further provides methods for using the liquid reagent sets.

7. 发明授权

EP1218532B1 Method for monitoring an analyte using an electrochemical Biosensor which can be turned off by applying an electrical potential 有权
标题翻译：使用电化学生物传感器，可以通过施加电势被切断测量分析物的方法
公开(公告)号：EP1218532B1
公开(公告)日：2007-12-26
申请号：EP00965134.0
申请日：2000-09-19
申请人： Roche Diagnostics Operations, Inc. , Roche Diagnostics GmbH
发明人： BUCK, Harvey, B. , ESSENPREIS, Matthias
IPC分类号： C12Q1/00
CPC分类号： C12Q1/006 , C12Q1/004
摘要： Sensors (10, 110, 210, 310, 410) and a method for detecting an analyte are described. Sensors (10, 110, 210, 310, 410) each have a volume of a hydrophilic medium (24) that retains an amount of analyte proportionate to the concentration of analyte in a biological fluid, electrodes (12) and a redox enzyme in contact with medium (24), and an electron transfer mediator. The fluid contacts sensors (10, 110, 210, 310, 410) and at initially predetermined intervals intermittently applies a potential to electrode (12) sufficient to oxidize the mediator and sensing current through electrode (12) as a function of the duration of the applied potential. The applied mediator oxidizing applied potential is maintained for a period of time sufficient to determine the rate of change of current with time through electrode (12). The current flow is correlated with the current flow for known concentrations of the analyte in medium (24).

8. 发明公开

EP1862116A2 Disposable element for use in a body fluid sampling device 失效
标题翻译：一种用于在装置中使用的一次性元件，用于采集体液样品
公开(公告)号：EP1862116A2
公开(公告)日：2007-12-05
申请号：EP07113978.6
申请日：1997-05-16
申请人： Roche Diagnostics Operations, Inc.
发明人： Douglas, Joel S. , Roe, Jeffrey N. , Radwanski, Ryszard , Duchon, Brent G. , Sanchez, Michael J. , Grage, Henry M.
IPC分类号： A61B5/145 , A61B10/00 , A61B17/32
CPC分类号： B82Y30/00 , A61B5/14532 , A61B5/150022 , A61B5/150068 , A61B5/150343 , A61B5/150419 , A61B5/150427 , A61B5/150519 , A61B5/150824 , A61B5/150977 , A61B5/15111 , A61B5/15117 , A61B5/15194 , A61B10/0045 , A61B2010/008 , A61B2017/00765 , A61B2562/0295
摘要： A disposable lancing element (12) is adapted for use in a lancing device (10) for making an incision through a user's skin. The lancing element (12) includes a body (16) which defines a longitudinal axis, and has a skin lancing member projecting from a front end thereof. A capillary tube (18) is mounted in the body in laterally spaced relationship to the skin lancing member, and is slidable longitudinally relative to the body (16) so as to be extended forwardly past the skin lancing member. The body (16) includes a plurality of circumferentially spaced, radially outwardly projecting bosses (31) formed thereon for guiding the disposable element installation in a carrier element. The kin lancing member may comprise a plurality of needles (14) or barbs arranged in parallel side by side relationship. In lieu of a skin lancing member, the disposable element (12) may possess a longitudinal through hole for conducting a skin piercing laser light beam or pressurized fluid. A capillary tube (18) may have an outwardly flared lower (inlet) end. A capillary tube (18) may possess a sensor for sensing a level of fluid rising therein.
摘要翻译：甲一次性采血元件（12）是angepasst用于在穿刺装置（10），用于通过使用者的皮肤使在切口的使用。穿刺元件（12）包括主体（16），其限定了纵向轴线，且具有皮肤刺血构件从其前端伸出。甲毛细管（18）被安装在主体中尾盘反弹间隔关系到皮肤刺血构件和可滑动沿纵向相对于所述主体（16），以便被过去的皮肤刺血构件向前延伸。所述主体（16）包括用于在载体元件引导一次性元件安装在其上形成沿周向隔开，径向向外突出的凸台（31）的复数。的亲属刺血构件可包括由并列关系在平行并排布置的针（14）或倒钩的复数。代替皮肤穿刺体的，一次性元件（12）可以通过用于进行皮肤穿刺激光光线或加压流体孔纵向具有一个。甲毛细管（18）可以具有在向外张开的下部（入口）端。甲毛细管（18）可以具有一个传感器，用于感测流体在其中上升的电平。

9. 发明授权

EP0702789B8 BIOSENSING METER WHICH DETECTS PROPER ELECTRODE ENGAGEMENT AND DISTINGUISHES SAMPLE AND CHECK STRIPS 失效
标题翻译：电化学测量仪，用于检测适当的电极啮合和分析样品并检查样品条
公开(公告)号：EP0702789B8
公开(公告)日：2006-06-14
申请号：EP94919131.6
申请日：1994-05-13
申请人： Roche Diagnostics Operations, Inc.
发明人： WHITE, Bradley, E. , PARKS, Robert, A. , RITCHIE, Paul, G.
IPC分类号： G01N27/26 , G01N33/487
CPC分类号： G01N27/3273
摘要： A biosensing meter (50) receives a biomedical sample strip (10) which includes electrically isolated excitation (14) and sense (12) electrodes or, alternatively, a check strip. The biosensing meter includes first and second contacts (C, D) that are connected by a sense electrode upon insertion of a sample strip. An operational amplifier circuit has first and second inputs respectively connected to the first contact and a reference potential, the first input manifesting the reference potential as a result of a feedback within the operational amplifier. A processor (60) is coupled to the second contact and determines the presence of the reference potential at the second contact when an inserted sense electrode connects the first and second contacts. The processor also distinguishes between sample and check strips and tests for a proper impedance between the sense and excitation electrodes of a sample strip, thus enabling operation of the biosensing meter upon sample strip dosing.
摘要翻译：生物传感计量器（50）接收包括电隔离的激励（14）和感测（12）电极或替代地检查条的生物医学样品条（10）。生物传感计包括在插入样品条时通过传感电极连接的第一和第二触点（C，D）。运算放大器电路具有分别连接到第一触点和参考电位的第一和第二输入端，由于运算放大器内的反馈，第一输入端表现出参考电位。处理器（60）耦合到第二触点并且当插入的感测电极连接第一触点和第二触点时确定在第二触点处存在参考电位。处理器还区分样品条带和检测条带，并测试样品条带的感测电极和激励电极之间的适当阻抗，从而使样品条带定量给药时生物传感计量器能够运行。

10. 发明授权

EP0716738B1 MAGNETIC SYSTEM FOR MEDICAL INSTRUMENT 失效
标题翻译：磁系统医疗器械
公开(公告)号：EP0716738B1
公开(公告)日：2005-11-02
申请号：EP94925970.9
申请日：1994-08-18
申请人： Roche Diagnostics Operations, Inc.
发明人： PARKER, James, R. , MURPHY, William, J. , THOMECZEK, Charles, L., Jr. , KENNEDY, Daniel, L. , NEEL, Gary, T. , STORVICK, David, E.
IPC分类号： G01N11/10 , G01N33/49 , G01N11/16
CPC分类号： G01N33/4905 , G01N11/16
摘要： An instrument (100) monitors the coagulation of coagulable fluid blood, blood fraction or a control (514) by combining (101) the coagulable fluid (514) with particles which are affected by a magnetic field so that the particles become suspended relatively freely in the fluid. A time-varying magnetic field (2 Hz) causes the particles to be reoriented as the magnetic field varies. The reorientation changes as the fluid (514) coagulates owing to the fluid's (514's) changing viscosity. An electromagnet (140) creates the time-varying magnetic field. The electromagnet (140) includes a core (150) comprising a first leg (148), an electrically conductive coil (144) for creating a time-varying magnetic flux in the core (150), and a return (152) for the time-varying magnetic flux. The first leg (148) and the flux return (152) together comprise a generally E-shaped core (150) of ferromagnetic material. A bobbin (146) is provided on the first leg (148) and the electrically conductive coil (144) is wound on the bobbin (146).

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