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    • 2. 发明公开
    • SAMPLING DEVICE INTERFACES
    • 采样设备接口
    • EP3243435A1
    • 2017-11-15
    • EP17168976.3
    • 2011-01-13
    • Seventh Sense Biosystems, Inc.
    • Chickering, Donald, E.Davis, ShawnHaghgooie, RaminBernstein, HowardLevinson, Douglas, A.
    • A61B5/151
    • A61B5/14532A61B5/150022A61B5/150099A61B5/150221A61B5/150229A61B5/150236A61B5/150244A61B5/150297A61B5/150389A61B5/150412A61B5/150503A61B5/150755A61B5/150969A61B5/150977A61B5/150984A61B5/15105A61B5/15113A61B5/15117A61B5/15125A61B5/15144A61B5/15186A61B5/157A61B5/685
    • The present invention generally relates to systems and methods for delivering and/or withdrawing a substance or substances such as blood or interstitial fluid, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for withdrawing or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to withdraw blood from the subject. The device, in some cases, may be interfaced with external equipment to determine an analyte contained within a fluid contained within or collected by the device. For example, the device may be mounted or engaged on an external holder, the device may include a port for transporting fluid out of the device, the device may include a window for interrogating a fluid contained within the device, or the like. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. For example, blood may be withdrawn from the device, and/or the device may contain sensors or agents able to determine the blood and/or an analyte suspected of being contained in the blood. Other aspects of the present invention are directed at other devices for withdrawing blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like.
    • 本发明总体上涉及用于从受试者(例如从皮肤和/或从皮肤下方)输送和/或排出一种或多种物质(例如血液或间质液)的系统和方法。 在一个方面,本发明总体上涉及用于使用含有液体转运体的装置(例如,一个或多个微针)从受试者(例如从皮肤和/或皮肤下面)抽取或抽取血液的装置和方法 )以及在接收血液之前具有小于大气压的内部压力的储存室。 在一些情况下,该装置可以是独立的,并且在某些情况下,该装置可以被施加到皮肤上,并被激活以从受试者中抽取血液。 该装置在某些情况下可以与外部设备连接以确定装置内包含的或被装置收集的流体内包含的分析物。 例如,该装置可以被安装或接合在外部保持器上,该装置可以包括用于将流体输送出装置的端口,该装置可以包括用于询问容纳在装置内的流体的窗口等。 然后可以处理装置或其一部分,以单独地或利用外部装置来确定血液和/或血液内的分析物。 例如,血液可以从装置中取出,和/或装置可以包含能够确定血液和/或怀疑包含在血液中的分析物的传感器或试剂。 本发明的其它方面针对用于抽取血液(或其他体液,例如间质液)的其他装置,涉及这种装置的套件,制造这种装置的方法,使用这些装置的方法等。