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1. 发明公开

EP3386376A1 SYSTEMS AND METHODS FOR NON-INVASIVE BLOOD PRESSURE MEASUREMENT 有权
公开(公告)号：EP3386376A1
公开(公告)日：2018-10-17
申请号：EP16871674.4
申请日：2016-12-02
申请人： Spry Health, Inc.
发明人： FERBER, Elad , COBUT, Pierre-Jean , NARAYANAN, Ramkrishnan , GUNGOR, Derya Gol
IPC分类号： A61B5/00
CPC分类号： A61B5/7221 , A61B5/0002 , A61B5/0008 , A61B5/0022 , A61B5/0064 , A61B5/0205 , A61B5/021 , A61B5/02125 , A61B5/02141 , A61B5/024 , A61B5/02416 , A61B5/0806 , A61B5/117 , A61B5/14532 , A61B5/14535 , A61B5/14539 , A61B5/14546 , A61B5/1455 , A61B5/14551 , A61B5/4872 , A61B5/6802 , A61B5/6816 , A61B5/6823 , A61B5/6824 , A61B5/6829 , A61B5/721 , A61B5/7264 , A61B5/7275 , A61B5/7435 , G06F19/00
摘要： Systems and methods for non-invasive respiratory rate measurement are disclosed. In some embodiments, a system comprises a wearable member including an energy transmitter configured to project energy into tissue of a user. An energy receiver generates a multichannel signal based on a first received portion of the energy, the received portion of energy being received through the tissue of the user. A respiratory rate calculation system includes a pre-processing module for filter noise from the signal. A spectrum module determines a spectrum of the signal. A respiratory rate processing module determines a first respiratory rate from the spectrum of the signal. A noise reference and one or more second respiratory rates are obtained. A third respiratory rate is determined based on the first respiratory rate, the noise reference, and the one or more second respiratory rates. A communication module provides a message based on the third respiratory rate.

2. 发明公开

EP3340859A1 DISPOSITIF ET PROCÉDÉ DE MESURE NON-INVASIVE DU DÉBIT AORTIQUE SOUS-DIAPHRAGMATIQUE CHEZ UN PETIT MAMMIFERE DE LABORATOIRE 有权转让
公开(公告)号：EP3340859A1
公开(公告)日：2018-07-04
申请号：EP16770059.0
申请日：2016-08-26
申请人： Université Grenoble Alpes
发明人： BACONNIER, Pierre , BOUCHER, François , GUMERY, Pierre-Yves
IPC分类号： A61B5/00 , A61B5/0295 , A61B5/05 , A61B5/0408 , A61B5/08 , A61B5/113
CPC分类号： A61B5/0295 , A61B5/0205 , A61B5/0265 , A61B5/0402 , A61B5/04085 , A61B5/05 , A61B5/0806 , A61B5/1135 , A61B5/6804 , A61B5/6823 , A61B5/7225 , A61B5/725 , A61B5/7278 , A61B7/04 , A61B2503/40 , A61B2503/42 , A61B2562/0219
摘要： The invention relates to a device for non-invasive measurement of aortic flow in the subdiaphragmatic region in a small laboratory mammal, characterised in that it comprises: - a device for plethysmography of the thorax by inductance measurement, comprising two electrically conducting, extendible coils (2, 3) rigidly attached to an elastic garment (1) that is adjustable to the torso of said mammal (A), - a device (4) for acquiring the signal from variation in the cross-section of each coil, - a processor (6) configured to calculate the instantaneous subdiaphragmatic aortic flow of said mammal from said signals from the variation in cross-section of each coil and from a functional model of the cardiorespiratory system, according to which the exchanges of blood between the thorax and the rest of the body of said mammal consist of an output of blood via the abdominal aorta in the subdiaphragmatic region and an input of blood via the inferior vena cava.

3. 发明公开

EP3148426A2 METHOD, SYSTEM AND SOFTWARE FOR ASSESSING EXTUBATION FAILURE 有权
标题翻译： VERFAHREN，系统软件ZURSCHÄTZUNGEINES EXTUBATIONSVERSAGENS
公开(公告)号：EP3148426A2
公开(公告)日：2017-04-05
申请号：EP15799200.9
申请日：2015-05-28
申请人： Children's Hospital Los Angeles
发明人： KHEMANI, Robinder , FLINK, Rutger , NEWTH, Christopher JL
IPC分类号： A61B5/0402 , A61B5/091 , A61B5/1455
CPC分类号： A61B5/0816 , A61B5/0205 , A61B5/037 , A61B5/0806 , A61B5/085 , A61B5/091 , A61B5/4233 , G06F19/00 , G06F19/3481 , Y02A90/26
摘要： A method, system and software for monitoring a signal from a living subject to measure a function of the living subject. Specifically, a computer method, computer system and software for accurately calibrating respiratory inductance plethysmography and esophageal manometry signals to measure effort of breathing before and after extubation of a patient to provide an automated real-time interpretation for a clinician of whether or not the patient has upper airway obstruction, and severity of the same. The method, system and software can be adapted specifically for a child or infant.
摘要翻译：一种用于监测来自活体的信号的方法，系统和软件，以测量活体的功能。具体地说，一种计算机方法，计算机系统和用于精确地校准呼吸电感体积描记法和食管压力测量信号的软件，以测量患者拔管之前和之后的呼吸努力，以便为临床医生提供是否患者具有的自动化实时解释上呼吸道阻塞，严重程度相同。该方法，系统和软件可以专门适用于儿童或婴儿。

4. 发明公开

EP2946730A1 VERFAHREN ZUR VERMESSUNG DES ATEMVORGANGS EINES PATIENTEN WÄHREND EINER MAGNETRESONANZUNTERSUCHUNG, MESSANORDNUNG UND MAGNETRESONANZEINRICHTUNG 审中-公开
标题翻译：方法用于测量患者的呼吸过程期间，磁力探伤，测量装置和磁器件
公开(公告)号：EP2946730A1
公开(公告)日：2015-11-25
申请号：EP15164593.4
申请日：2015-04-22
申请人： Siemens Aktiengesellschaft
发明人： Biber, Stephan , Fackelmeier, Andreas , Rehner, Robert
IPC分类号： A61B5/055
CPC分类号： A61B5/0806 , A61B5/0535 , A61B5/055 , A61B5/0555 , A61B5/0809 , A61B5/0816 , A61B5/6892 , A61B5/721 , A61B5/7285 , G01R33/28 , G01R33/3621 , G01R33/56509 , G01R33/5673
摘要： Verfahren zur Vermessung des Atemvorgangs eines Patienten (5) während einer Magnetresonanzuntersuchung mit einer Magnetresonanzeinrichtung (1), dadurch gekennzeichnet, dass die Reflektionseigenschaften wenigstens eines unterhalb des Patienten (5) angeordneten Spulenelements (6) vermessen und zur Ermittlung von den Atemzustand zu verschiedenen Zeitpunkten beschreibenden Atmungsdaten ausgewertet werden.
摘要翻译：一种用于磁共振检查与磁共振装置中测量患者（5）的呼吸过程的方法（1），其特征在于，（6）测得的，和用于确定在描述不同时间的呼吸状态的至少一个的所述患者（5）下方的反射特性布置线圈元件呼吸数据进行评估。

5. 发明公开

EP2667934A4 APPARATUS AND METHODS FOR ASSISTING BREATHING 有权
标题翻译：用于呼吸支持的装置和方法
公开(公告)号：EP2667934A4
公开(公告)日：2014-09-17
申请号：EP12739018
申请日：2012-01-25
申请人： APELLIS HOLDINGS LLC
发明人： FRANCOIS CEDRIC , MCLACHLAN ANGUS
IPC分类号： A61N1/36 , A61B5/00 , A61B5/08 , A61B5/113 , A61H9/00 , A61H11/00 , A61H31/00 , A61M16/00
CPC分类号： A61H9/0078 , A61B5/0806 , A61B5/1135 , A61B5/6804 , A61B5/7264 , A61H31/00 , A61H2011/005 , A61H2201/10 , A61H2201/1619 , A61H2201/165 , A61H2201/5007 , A61H2201/5015 , A61H2201/5035 , A61H2201/5046 , A61H2201/5061 , A61H2201/5082 , A61H2201/5084 , A61H2205/083 , A61H2230/065 , A61H2230/208 , A61H2230/305 , A61H2230/405 , A61H2230/505 , A61H2230/605 , A61H2230/625 , A61N1/3601 , A61N1/36014 , A61N2/002
摘要： The present invention provides, among other things, apparatus and methods of use for treating a subject in need of assistance with breathing. In some embodiments the subject suffers from airflow obstruction. In some embodiments, the subject suffers from chronic obstructive pulmonary disease.

6. 发明公开

EP2324760A3 Systems and methods for ambulatory monitoring of physiological signs 审中-公开
标题翻译：生理迹象流动监测的系统和方法
公开(公告)号：EP2324760A3
公开(公告)日：2014-06-18
申请号：EP10195599.5
申请日：2001-04-17
申请人： Adidas AG
发明人： Sackner, Marvin A. , Inman, D. Michael
IPC分类号： A61B5/0205 , A61B5/113
CPC分类号： A61B5/0806 , A61B5/002 , A61B5/0022 , A61B5/0205 , A61B5/0402 , A61B5/04085 , A61B5/0428 , A61B5/0432 , A61B5/0535 , A61B5/0809 , A61B5/1073 , A61B5/1116 , A61B5/113 , A61B5/1135 , A61B5/6804 , A61B5/6805 , A61B5/6822 , A61B5/6824 , A61B5/7232 , A61B5/7239 , A61B7/003 , A61B2560/0271 , A61B2562/0219
摘要： The present invention relates to the field of ambulatory and non-invasive monitoring of a plurality of physiological parameters of a monitored individual. The invention includes a physiological monitoring apparatus with an improved monitoring apparel worn by a monitored individual, the apparel having attached sensors for monitoring parameters reflecting pulmonary function, or parameters reflecting cardiac function, or parameters reflecting the function of other organ systems, and the apparel being designed and tailored to be comfortable during the individual's normal daily activities. The apparel is preferably also suitable for athletic activities. The sensors preferably include one or more ECG leads and one of more inductive plethysmographic sensors with conductive loops positioned closely to the individual to preferably monitor at least basic cardiac parameters, basic pulmonary parameters, or both. The monitoring apparatus also includes a unit for receiving data from the sensors, and for storing the data in a computer-readable medium. The invention also includes systems comprising a central data repository for receiving, storing, and processing data generated by a plurality of physiological monitored apparatus, and for making stored data available to the individual and to the health care providers.
摘要翻译：本发明涉及监测个体的多个生理参数的流动和非侵入式监测领域。本发明包括具有由监测个体佩戴的改进的监测服装的生理监测装置，所述服装具有用于监测反映肺功能的参数的传感器或反映心脏功能的参数或反映其他器官系统的功能的参数，并且所述服装是设计并量身定制，在个人正常的日常活动中保持舒适。该服装最好也适用于运动。传感器优选地包括一个或多个ECG导联以及多个感应体积描记传感器中的一个，其具有与个体紧密定位的导电环，以优选监测至少基本心脏参数，基本肺参数或两者。监视装置还包括用于从传感器接收数据并将数据存储在计算机可读介质中的单元。本发明还包括包括中央数据仓库的系统，用于接收，存储和处理由多个生理监测装置产生的数据，并且使存储的数据对个人和健康护理提供者可用。

7. 发明公开

EP2589335A2 Systems and methods for respiratory event dedection 审中-公开
标题翻译： Systeme und Verfahren zur Atmungsereigniserkennung
公开(公告)号：EP2589335A2
公开(公告)日：2013-05-08
申请号：EP13152334.2
申请日：2004-04-09
申请人： Adidas AG
发明人： Coyle, Michael , Keenan, Desmond B. , Derchak, Alexander P. , Sackner, Marvin A. , Wilhelm, Frank , Gilroy, Keith , Gummels, Emerance M. , Inman, Dana Michael , Kennedy, Paul , Mitchnik, Mark , Behar, Andrew
IPC分类号： A61B5/08 , A61B5/113
CPC分类号： A61B5/0806 , A61B5/0823 , A61B5/091 , A61B5/1135 , A61B5/4818 , A61B5/6805 , A61B5/721 , A61B5/725 , A61B5/7267 , A61B7/003 , A61B2562/0219 , G06F19/00
摘要： The present invention is directed to an improved method for determining respiratory parameters. The method is capable of discriminating particular respiratory from base respiratory events and comprises the steps: a.) receiving respiratory signals (21) from one or more monitored subjects such that the respiratory signals include one or more particular respiratory events (37-45) and one or more base respiratory events, b.) evaluating the capability of individual respiratory parameters and of combinations of respiratory parameters to statistically discriminate between the particular and the base respiratory events, and c.) selecting an individual respiratory parameter or a combination of respiratory parameters with adequate discriminatory capability.
摘要翻译：本发明涉及用于确定呼吸参数的改进方法。该方法能够区分特定的呼吸与基础呼吸事件，并且包括以下步骤：a）从一个或多个监测对象接收呼吸信号（21），使得呼吸信号包括一个或多个特定呼吸事件（37-45）和一个或多个基础呼吸事件，b）评估个体呼吸参数的能力和呼吸参数的组合以统计学地区分特定和基础呼吸事件，以及c）选择个体呼吸参数或呼吸参数的组合具有足够的歧视能力。

8. 发明公开

EP2508124A2 System for processing data from ambulatory physiological monitoring 审中-公开
标题翻译：用于处理动态生理监测数据的系统
公开(公告)号：EP2508124A2
公开(公告)日：2012-10-10
申请号：EP11187663.7
申请日：2004-11-18
申请人： Adidas AG
发明人： Keenan, Desmond B. , Coyle, Michael
IPC分类号： A61B5/0205 , A61B5/0402 , A61B5/08 , A61B5/107
CPC分类号： A61B5/721 , A61B5/0002 , A61B5/01 , A61B5/0205 , A61B5/02055 , A61B5/029 , A61B5/0402 , A61B5/0456 , A61B5/0468 , A61B5/0476 , A61B5/0488 , A61B5/0806 , A61B5/085 , A61B5/1073 , A61B5/4803 , A61B5/6804 , A61B5/725 , A61B2560/0242 , A61B2562/0219 , G06F19/00
摘要： This invention provides a system for processing physiological sensor signal data comprising: a wearable construction comprising one or more sensors sensitive to physiological systems or processes comprising electrocardiographic (ECG) activity and respiratory activity; and computer memory comprising computer instructions toretrieve sensor signals from said wearable construction when worn by a monitored subject during periods comprising unconstrained activities, said retrieved sensor signals comprising ECG signals and respiratory signals; generate an RR interval signal from said ECG signal comprising data describing successive intervals between successive R-waves; and estimate respiratory components in said ECG signal by adaptively processing said ECG signals jointly with said respiratory signals in order to reduce an error signal, wherein a high frequency heart rate variability (HF HRV) signal comprises said estimated respiratory components, a low frequency heart rate variability (LF HRV) signal comprises said error signal.
摘要翻译：本发明提供了一种用于处理生理传感器信号数据的系统，包括：包括一个或多个传感器的可佩戴构造，所述传感器对包括心电图（ECG）活动和呼吸活动的生理系统或过程敏感; 以及包括计算机指令的计算机存储器，所述计算机指令用于在由包括ECG信号和呼吸信号的时间段期间由被监测对象佩戴时从所述可佩戴构造中检测传感器信号; 从所述ECG信号生成包括描述连续R波之间的连续间隔的数据的RR间隔信号; 并且通过与所述呼吸信号一起自适应地处理所述ECG信号来估计所述ECG信号中的呼吸成分，以便减少误差信号，其中高频心率变异性（HF HRV）信号包括所述估计的呼吸成分，低频心率可变性（LF HRV）信号包括所述误差信号。

9. 发明公开

EP2508123A1 Method and system for processing data from ambulatory physiological monitoring 有权
标题翻译：系统zur Verarbeitung von Daten aus ambulanter生理学家Überwachung
公开(公告)号：EP2508123A1
公开(公告)日：2012-10-10
申请号：EP11187662.9
申请日：2004-11-18
申请人： Adidas AG
发明人： Keenan, Desmond B. , Coyle, Michael
IPC分类号： A61B5/0205 , A61B5/0402 , A61B5/08 , A61B5/0476 , A61B5/103
CPC分类号： A61B5/721 , A61B5/0002 , A61B5/01 , A61B5/0205 , A61B5/02055 , A61B5/029 , A61B5/0402 , A61B5/0456 , A61B5/0468 , A61B5/0476 , A61B5/0488 , A61B5/0806 , A61B5/085 , A61B5/1073 , A61B5/4803 , A61B5/6804 , A61B5/725 , A61B2560/0242 , A61B2562/0219 , G06F19/00
摘要： A system for processing physiological sensor signal data comprising:a wearable construction comprising one or more sensors sensitive to physiological systems or processes comprising electroencephalographic (EEG) activity and respiratory activity; and computer memory comprising computer instructions to retrieve sensor signals from said wearable construction when worn by a monitored subject during periods comprising unconstrained activities, said retrieved sensor signals comprising EEG signals and respiratory signals; estimate respiratory components in said EEG signal by adaptively processing said EEG signals jointly with said respiratory signals in order to reduce an error signal; and enhance desired EEG components relative to undesired respiratory components in said EEG signals in dependence on said estimated respiratory components.
摘要翻译：一种用于处理生理传感器信号数据的系统，包括：可佩戴结构，包括对生理系统敏感的一个或多个传感器或包括脑电图（EEG）活动和呼吸活动的过程; 以及计算机存储器，包括计算机指令，用于在由包含无约束活动的周期期间由受监控对象佩戴时从所述可佩戴结构中检索传感器信号，所述检索的传感器信号包括脑电信号和呼吸信号; 通过与所述呼吸信号联合自适应地处理所述EEG信号来估计所述EEG信号中的呼吸成分，以便减少误差信号; 并且根据所述估计的呼吸成分，在所述EEG信号中增强相对于不希望的呼吸成分的期望的EEG成分。

10. 发明公开

EP2324761A2 Systems and methods for ambulatory monitoring of physiological signals 审中-公开
标题翻译：用于生理信号的动态监测的系统和方法
公开(公告)号：EP2324761A2
公开(公告)日：2011-05-25
申请号：EP10195425.3
申请日：2001-04-17
申请人： Adidas AG
发明人： Sackner, Marvin A. , Inman, D. Michael
IPC分类号： A61B5/0205 , A61B5/113 , A61B5/0432
CPC分类号： A61B5/0806 , A61B5/002 , A61B5/0022 , A61B5/0205 , A61B5/0402 , A61B5/04085 , A61B5/0428 , A61B5/0432 , A61B5/0535 , A61B5/0809 , A61B5/1073 , A61B5/1116 , A61B5/113 , A61B5/1135 , A61B5/6804 , A61B5/6805 , A61B5/6822 , A61B5/6824 , A61B5/7232 , A61B5/7239 , A61B7/003 , A61B2560/0271 , A61B2562/0219 , G06F19/00
摘要： The present invention relates to the field of ambulatory and non-invasive monitoring of a plurality of physiological parameters of a monitored individual. The invention includes a physiological monitoring apparatus with an improved monitoring apparel worn by a monitored individual, the apparel having attached sensors for monitoring parameters reflecting pulmonary function, or parameters reflecting cardiac function, or parameters reflecting the function of other organ systems, and the apparel being designed and tailored to be comfortable during the individual's normal daily activities. The apparel is preferably also suitable for athletic activities. The sensors preferably include one or more ECG leads and one of more inductive plethysmographic sensors with conductive loops positioned closely to the individual to preferably monitor at least basic cardiac parameters, basic pulmonary parameters, or both. The monitoring apparatus also includes a unit for receiving data from the sensors, and for storing the data in a computer-readable medium. The invention also includes systems comprising a central data repository for receiving, storing, and processing data generated by a plurality of physiological monitored apparatus, and for making stored data available to the individual and to the health care providers.
摘要翻译：本发明涉及监测个体的多个生理参数的流动和非侵入式监测领域。本发明包括具有由监测个体佩戴的改进的监测服装的生理监测装置，所述服装具有用于监测反映肺功能的参数的传感器或反映心脏功能的参数或反映其他器官系统的功能的参数，并且所述服装是设计并量身定制，在个人正常的日常活动中保持舒适。该服装最好也适用于运动。传感器优选地包括一个或多个ECG导联以及多个感应体积描记传感器中的一个，其具有与个体紧密定位的导电环，以优选监测至少基本心脏参数，基本肺参数或两者。监视装置还包括用于从传感器接收数据并将数据存储在计算机可读介质中的单元。本发明还包括包括中央数据仓库的系统，用于接收，存储和处理由多个生理监测装置产生的数据，并且使存储的数据对个人和健康护理提供者可用。

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