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1. 发明公开

EP3364874A1 MULTI-VECTOR SENSING IN CARDIAC DEVICES WITH SIGNAL COMBINATIONS 审中-公开
公开(公告)号：EP3364874A1
公开(公告)日：2018-08-29
申请号：EP16794787.8
申请日：2016-10-20
申请人： Cardiac Pacemakers, Inc.
发明人： BRISBEN, Amy Jean , ALLAVATAM, Venugopal , SIEJKO, Krzysztof Z. , MAHAJAN, Deepa , WIKA, Kevin G. , HERRMANN, Keith L. , HAHN, Stephen J.
IPC分类号： A61B5/0402 , A61B5/00 , A61B5/0456 , A61B5/0468 , A61N1/39 , A61B5/04 , A61B5/042 , A61N1/362 , A61B5/024 , A61B5/0245 , A61B5/0472 , A61B5/0452
CPC分类号： A61N1/36514 , A61B5/02416 , A61B5/0245 , A61B5/04011 , A61B5/04012 , A61B5/04017 , A61B5/0402 , A61B5/04028 , A61B5/042 , A61B5/0422 , A61B5/0452 , A61B5/04525 , A61B5/0456 , A61B5/0468 , A61B5/0472 , A61B5/686 , A61B5/6869 , A61B5/72 , A61B5/7203 , A61B5/7221 , A61N1/046 , A61N1/05 , A61N1/0563 , A61N1/3622 , A61N1/3625 , A61N1/3704 , A61N1/3925 , A61N1/3956 , A61N1/3987
摘要： New and alternative approaches to the monitoring of cardiac signal quality for external and/or implantable cardiac devices. In one example, signal quality is monitored continuously or in response to a triggering event or condition and, upon identification of a reduction in signal quality, a device may reconfigure its sensing state. In another example, one or more trends of signal quality are monitored by a device, either continuously or in response to a triggering event or condition, and sensing reconfiguration may be performed in response to identified trends and events. In yet another example, a device may use a looping data capture mode to track sensing data in multiple vectors while primarily relying on less than all sensing vectors to make decisions and, in response to a triggering event or condition, the looped data can be analyzed automatically, without waiting for additional data capture to reconfigure sensing upon identification of the triggering event or condition. In another example a device calculates a composite cardiac cycle by overlaying signal morphology for a number of cardiac cycles and analyzes the composite cardiac cycle to calculate signal quality metrics.

2. 发明公开

EP3312765A1 ANOMALY DETECTION BY SELF-LEARNING OF SENSOR SIGNALS 有权
标题翻译：通过传感器信号的自学习来进行异常检测
公开(公告)号：EP3312765A1
公开(公告)日：2018-04-25
申请号：EP17160491.1
申请日：2017-03-13
申请人： Tata Consultancy Services Limited
发明人： Bandyopadhyay, Soma , UKIL, Arijit , Singh, Rituraj , Puri, Chetanya , Pal, Arpan , Murthy, C A
IPC分类号： G06K9/00 , G06F17/18 , A61B5/0468
CPC分类号： A61B5/7267 , A61B5/021 , A61B5/0468 , A61B5/14551 , G06F17/18 , G06K9/0053 , G06N99/005
摘要： Accurate detection of anomaly in sensor signals is critical and can have an immense impact in the health care domain. Accordingly, identifying outliers or anomalies with reduced error and reduced resource usage is a challenge addressed by the present disclosure. Self-learning of normal signature of an input sensor signal is used to derive primary features based on valley and peak points of the sensor signals. A pattern is recognized by using discrete nature and strictly rising and falling edges of the input sensor signal. One or more defining features are identified from the derived features based on statistical properties and time and frequency domain properties of the input sensor signal. Based on the values of the defining features, clusters of varying density are identified for the input sensor signal and based on the density of the clusters, anomalous and non-anomalous portions of the input sensor signals are classified.
摘要翻译：准确检测传感器信号中的异常非常重要，并且可能会对医疗保健领域产生巨大影响。因此，识别具有减少的错误和减少的资源使用的异常值或异常是本公开所解决的挑战。输入传感器信号的正常特征的自学习被用于基于传感器信号的谷点和峰值点导出主要特征。通过使用输入传感器信号的离散特性和严格的上升和下降沿来识别模式。基于输入传感器信号的统计特性以及时间和频率域属性，从派生特征中识别一个或多个定义特征。基于定义特征的值，针对输入传感器信号识别变密度的簇，并且基于簇的密度，对输入传感器信号的异常和非异常部分进行分类。

3. 发明授权

EP3021743B1 SYSTEM FOR GENERATING ELECTROPHYSIOLOGY MAPS 失效
公开(公告)号：EP3021743B1
公开(公告)日：2018-01-31
申请号：EP14792650.5
申请日：2014-10-03
申请人： St. Jude Medical, Cardiology Division, Inc.
发明人： DENO, D. Curtis
IPC分类号： A61B5/00 , A61B5/042
CPC分类号： A61B5/04012 , A61B5/021 , A61B5/042 , A61B5/0422 , A61B5/0464 , A61B5/0468 , A61B5/743 , A61B5/7435
摘要： A method of generating a cardiac electrophysiology map includes receiving a reference biological signal and an electrical signal indicative of electrical activity at a location on a patient's heart. Using a graphical user interface, a practitioner designates at least two trigger point icons, one upward-pointing and one downward-pointing, on a graphical representation of the reference biological signal (e.g., a waveform). By pairing one upward-pointing icon with one downward-pointing icon, a plurality of triggering criteria are defined. Electrophysiology data points are captured and/or added to the electrophysiology map when the triggering criteria are satisfied.

4. 发明公开

EP3251594A1 METHOD FOR THE DETECTING ELECTROCARDIOGRAM ANOMALIES AND CORRESPONDING SYSTEM 有权
标题翻译：检测心电图异常的方法和相应的系统
公开(公告)号：EP3251594A1
公开(公告)日：2017-12-06
申请号：EP17150350.1
申请日：2017-01-05
申请人： STMicroelectronics S.r.l.
发明人： ROSSI, Beatrice , FRAGNETO, Pasqualina , ZAMBON, Daniele , CARRERA, Diego , BORACCHI, Giacomo
IPC分类号： A61B5/0472 , A61B5/0468 , A61B5/0452 , A61B5/00 , A61B5/11 , A61B5/04 , A61B5/0456
CPC分类号： A61B5/7267 , A61B5/0022 , A61B5/02438 , A61B5/0245 , A61B5/04012 , A61B5/04017 , A61B5/0402 , A61B5/04525 , A61B5/0456 , A61B5/0468 , A61B5/0472 , A61B5/1118 , A61B5/7207 , A61B5/7221 , A61B5/7232 , A61B5/7253 , A61B5/7278 , A61B2505/07 , A61B2562/0219
摘要： A heartrate monitor detects (1604) heartbeats in a test signal. A local heartrate and an energy of acceleration are associated (1606, 1608, 1610) with the detected heartbeats. Detected heartbeats are included or excluded (1612) from a test set of heartbeats based on the local heartrate and energy of acceleration associated with the respective heartbeats. Anomalous heartbeats in the test set of heartbeats are detected (1622) using a sparse approximation model (1620). The heartrate monitor may detect heartbeats in a training heartbeat signal. A reference heart rate and an energy of acceleration are associated with detected beats of the training heartbeat signal and selectively included in a set of training data based on the heart rate and energy of acceleration associated with the detected beat in the training heartbeat signal. A dictionary of the sparse representation model may be generated using the set of training data.
摘要翻译：心率监视器检测（1604）测试信号中的心跳。一个本地心脏和一个加速能量与检测到的心跳相关联（1606,1608,1610）。基于局部心率和与相应心跳相关联的加速能量，从心跳测试组中包括或排除检测到的心跳（1612）。使用稀疏近似模型（1620）检测心脏检测集合中的异常心跳（1622）。心率监测器可以检测训练心跳信号中的心跳。基准心率和加速能量与训练心跳信号的检测到的节拍相关联，并基于与训练心跳信号中与检测到的节拍相关联的加速度的心率和能量选择性地包括在一组训练数据中。可以使用该组训练数据来生成稀疏表示模型的字典。

5. 发明公开

EP3119276A4 SYSTEM AND METHODS FOR USING BODY SURFACE CARDIAC ELECTROGRAM INFORMATION COMBINED WITH INTERNAL INFORMATION TO DELIVER THERAPY 有权
公开(公告)号：EP3119276A4
公开(公告)日：2017-11-22
申请号：EP15765634
申请日：2015-03-19
申请人： CARDIONXT INC
发明人： EDWARDS JEROME RANJEEV , KESSMAN PAUL , NGUYEN BAO
IPC分类号： A61B5/0402 , A61B5/06 , A61B90/00
CPC分类号： A61B19/5244 , A61B5/0037 , A61B5/0044 , A61B5/04085 , A61B5/0468 , A61B5/055 , A61B5/062 , A61B5/064 , A61B5/065 , A61B5/066 , A61B5/6805 , A61B5/684 , A61B5/6852 , A61B5/6869 , A61B5/7289 , A61B5/743 , A61B6/503 , A61B6/5288 , A61B8/12 , A61B8/4254 , A61B8/4263 , A61B8/5261 , A61B18/00 , A61B34/20 , A61B90/00 , A61B2034/107 , A61B2034/2051 , A61B2034/301 , A61B2090/363 , A61B2090/3782 , A61B2090/3954 , A61B2090/3966 , A61B2090/3983 , A61B2576/023 , A61N1/37211 , A61N1/37264
摘要： A system and method for co-registering body surface cardiac electrogram information to internal information is described. One embodiment comprises a rigid plate configured to be placed on a patient that includes imaging fiducials arranged in a unique orientation with respect to each other; a position sensor configured to provide position information of the rigid plate; multiple body surface electrodes coupled to the rigid plate for measuring cardiac electrical activity of the patient; and a control unit configured to receive an image scan of the patient, receive the cardiac electrical activity information from the body surface electrodes, receive position information of the rigid plate, and transform the cardiac electrical activity information from its coordinate system into the coordinate system of the position information of the rigid plate.

6. 发明公开

EP3155964A1 A METHOD AND A MONITORING DEVICE FOR ANALYZING ECG DATA BY COMPARING CONSECUTIVE TIME INTERVALS 有权
标题翻译：方法和分析的心电数据，通过比较连续的时间间隔一个ÜBERWACHUNGSGEÄT
公开(公告)号：EP3155964A1
公开(公告)日：2017-04-19
申请号：EP16188684.1
申请日：2016-09-14
申请人： BIOTRONIK SE & Co. KG
发明人： Bellock, Steven , Whittington, R. Hollis , Garner, Garth
IPC分类号： A61B5/0468
CPC分类号： A61B5/0468 , A61B5/04012 , A61B5/0422 , A61B5/0432
摘要： The disclosure describes a method for analyzing ECG data (200), comprising the steps of:
- detecting points in the ECG data which represent ventricular activity (101),
- measuring time intervals (210, 220, 211, 221, 212, 222) between each two consecutive points in the ECG data which represent ventricular activity,
- evaluating the time intervals within a set of time intervals by
- computing at least one comparative dimension for at least one time interval subset, wherein the time interval subset comprises at least two time intervals, wherein the comparative dimension represents a difference of the interval length between the time intervals of the time interval subset, wherein a fixed number N of time intervals lies between each two time intervals of the time interval subset and wherein N ≥ 1.
摘要翻译：本公开描述了用于分析ECG数据包括以下步骤的方法（200）： - 在ECG数据中检测点代表心室活动（101） - 测量时间间隔（210，220，211，221，212，222）计算用于至少一个时间间隔的子集的至少一个比较尺寸，worin的时间间隔的子集包括至少两个 - 通过评估一组时间间隔内的时间间隔 - 在ECG数据中的每个的两个连续点，这代表心室活动，之间的时间间隔，worin比较尺寸darstellt的时间间隔子集的时间间隔之间的时间间隔长度的差，worin时间间隔的固定数目N的时间间隔的子集和worinñ‰¥的每两个时间间隔之间位于第一

7. 发明公开

EP2967400A4 MULTI-CHANNEL CARDIAC MEASUREMENTS 审中-公开
标题翻译： MEHRKANALIGE HERZMESSUNGEN
公开(公告)号：EP2967400A4
公开(公告)日：2016-11-23
申请号：EP14770328
申请日：2014-03-11
申请人： APN HEALTH LLC
发明人： BRODNICK DONALD , SRA JASBIR
IPC分类号： A61B5/0452 , A61B5/00 , A61B5/024 , A61B5/0245 , A61B5/04 , A61B5/042 , A61B5/0456 , A61B5/0468
CPC分类号： A61B5/04017 , A61B5/02405 , A61B5/0245 , A61B5/04012 , A61B5/0422 , A61B5/0456 , A61B5/0468 , A61B5/7221 , A61B5/7239 , A61B5/7246 , A61B2505/05
摘要： An automatic method of determining local activation time (LAT) in multi-channel cardiac electrogram signals including a plurality of cardiac channels, the method comprising: (a) storing the cardiac channel signals; (b) selecting a mapping channel, a ventricular channel, and a reference channel from among the plurality of cardiac channels; (c) using the selected channels to compute first LAT values at a plurality of mapping-channel locations; (d) monitoring the quality of at least one selected channel; (e) if the quality of a monitored cardiac channel falls below a standard, replacing the sub-standard channel with another channel of the plurality of channels having an above-standard quality; and (f) computing second LAT values based on the replacement cardiac channel.
摘要翻译：一种在包括多个心脏通道的多通道心电图信号中确定局部激活时间（LAT）的自动方法，所述方法包括：（a）存储心脏通道信号; （b）从所述多个心脏通道中选择映射信道，心室信道和参考信道; （c）使用所选择的信道来计算多个映射信道位置处的第一LAT值; （d）监测至少一个所选频道的质量; （e）如果所监视的心脏通道的质量低于标准，则用具有高于标准质量的多个通道中的另一个通道代替子标准通道; 和（f）基于替换心脏通道计算第二LAT值。

8. 发明公开

EP3021744A1 SYSTEM AND METHOD FOR GENERATING ELECTROPHYSIOLOGY MAPS 有权
标题翻译：用于产生电生理学图谱的系统和方法
公开(公告)号：EP3021744A1
公开(公告)日：2016-05-25
申请号：EP14792651.3
申请日：2014-10-03
申请人： St. Jude Medical, Cardiology Division, Inc.
发明人： DENO, D. Curtis
IPC分类号： A61B5/042 , A61B18/14 , A61B5/0464 , A61B5/00
CPC分类号： A61B5/0468 , A61B5/042 , A61B5/0422 , A61B5/0464 , A61B5/743 , A61B18/1492 , A61B2018/00577 , G16H50/50
摘要： A method of mapping cardiac electrical activity includes the acquisition of electrophysiological signals and using signal processing hardware to process such signals to identify lateness attributes thereof. If the lateness attribute exceeds a lateness threshold, then the corresponding point on the patient's heart can be designated as a therapy (e.g., ablation) target. It is also contemplated to use an upper bound on the lateness threshold, such that the corresponding point on the patient's heart is only designated as a therapy target if the lateness attribute both exceeds the lateness threshold and does not exceed the lateness bound. Both late activation (“Late-A”) and late potential (“Late-P”) attributes are contemplated.
摘要翻译：映射心脏电活动的方法包括采集电生理信号并使用信号处理硬件来处理这些信号以识别其迟后属性。如果迟后属性超过迟后阈值，则可以将患者心脏上的对应点指定为治疗（例如，消融）目标。还考虑使用迟后阈值的上限，使得如果迟后属性都超过迟后阈值并且不超过迟后界限，则仅将病人心脏上的对应点指定为治疗目标。预期晚期激活（“晚期-A”）和晚期潜在（“晚期-P”）属性。

9. 发明公开

EP2441015A4 SYSTEMS AND METHODS FOR VIEWING PATIENT DATA 有权
标题翻译：系统和方法查阅病人资料
公开(公告)号：EP2441015A4
公开(公告)日：2016-05-18
申请号：EP10786670
申请日：2010-06-08
申请人： AIRSTRIP IP HOLDINGS LLC
发明人： POWELL WILLIAM CAMERON , MOORE STEPHEN TREY
IPC分类号： G06F17/00 , A61B5/0452 , G06F19/00
CPC分类号： G06F19/3487 , A61B5/0006 , A61B5/0022 , A61B5/0452 , A61B5/0468 , A61B5/74 , A61B5/7415 , A61B5/7435 , A61B5/7455 , A61B5/748 , G06F19/34 , G06F19/3418 , G16H15/00 , G16H50/20
摘要： Methods of measuring features of a digitally generated waveform include communicating patient data to a device that is remote from a source of the patient data, generating the waveform on a touch-screen display of the device, and measuring along an axis of the waveform. The measuring includes generating a first point corresponding to the waveform based on contact with the touch-screen display, generating a second point corresponding to the waveform based on contact with the touch-screen display, automatically measuring a distance between the first point and the second point along the axis upon generation of the second point, and displaying a value corresponding to the distance on the touch-screen display.

10. 发明公开

EP2890293A4 METHOD AND APPARATUS FOR IDENTIFYING HYPERGLYCAEMIA 审中-公开
标题翻译：方法和设备用于识别高血糖
公开(公告)号：EP2890293A4
公开(公告)日：2016-04-20
申请号：EP13832488
申请日：2013-08-29
申请人： UNIV SYDNEY TECH
发明人： NGUYEN HUNG
IPC分类号： A61B5/0468 , A61B5/00 , A61B5/024 , A61B5/0245 , A61B5/04 , A61B5/0456 , A61B5/145 , G06F19/00
CPC分类号： A61B5/04012 , A61B5/02405 , A61B5/0245 , A61B5/0456 , A61B5/0468 , A61B5/14532 , A61B5/7267 , A61B5/7282 , A61B5/7405 , A61B5/742 , A61B5/746 , G16H50/20
摘要： A method and apparatus for determining hyperglycaemia. The apparatus includes a sensor and a processor, to determine a QT interval of a patient and any rate of change of the QT interval (dQT/dt), and, output means, to provide an output signal indicative of hyperglycaemia using an algorithm based on the combination of the QT interval and the rate of change of the QT interval. The apparatus may further include further sensor means, to determine a TpTec parameter and the SDNN parameter of a patient, whereby the processor further determines any rate of change of the TpTec parameter (dTpTec/dt) and the SDNN parameter to provide an output signal based on any one or combination of the QT interval, the TpTec parameter, the SDNN parameter and the rate of change of these parameters.

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