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1. 发明授权

EP0919197B1 Device for trans myocardial cryo revascularization 有权
标题翻译： Kryogenvorrichtung楚transmyokardialen Revaskularisation
公开(公告)号：EP0919197B1
公开(公告)日：2005-02-16
申请号：EP98204029.7
申请日：1998-11-30
申请人： Galil Medical Ltd
发明人： Ammar, Rony , Bliweis, Mordechai , Ofer, Glinka , Sturlesi, Gideon, Even
IPC分类号： A61B18/00
CPC分类号： A61B18/02 , A61B2017/00243 , A61B2017/00247 , A61B2018/00392 , A61B2018/0287 , F25B2309/021

2. 发明授权

EP0857464B1 Cryosurgical probe 失效
标题翻译：冷冻探针
公开(公告)号：EP0857464B1
公开(公告)日：2003-03-26
申请号：EP98201102.5
申请日：1994-11-09
申请人： SPEMBLY MEDICAL LIMITED
发明人： Varney, Kelvin John , Reeves, Simon Richard
IPC分类号： A61B18/00
CPC分类号： A61B18/02 , A61B2017/00092 , A61B2017/00123 , A61B2017/00243 , A61B2017/00292 , A61B2017/003 , A61B2018/00011 , A61B2018/0212 , A61B2018/0281 , A61B2018/0287

3. 发明公开

EP0932360A1 BIOCID AUSGERÜSTETES, FASERVERSTÄRKTES SCHWAMMTUCH 失效
标题翻译：杀菌剂的装备，纤维增强布海绵
公开(公告)号：EP0932360A1
公开(公告)日：1999-08-04
申请号：EP97944841.0
申请日：1997-09-06
申请人： Kalle Nalo GmbH & Co. KG
发明人： MANS, Leo , HAMMER, Klaus-Dieter
IPC分类号： A47L13 , A61K9 , C08J9 , C08K5 , C08L1 , A61B18
CPC分类号： C08L1/06 , A47L13/17 , A61B2018/0287 , C08K5/0058
摘要： The present invention relates to a regenerated cellulose based sponge material with an inner viscose fibre reinforcement having a staple fibre length of 5-50 mm and impregnated with a biocide agent. Also disclosed is a regenerated cellulose based sponge material with an inner cotton fibre reinforcement having a staple fibre length of 5-50 mm and impregnated with a biocide agent.

4. 发明公开

EP0608927A2 Fast changing heating-cooling device and method 失效
标题翻译：装置和方法用于快速交替加热和/或冷却。
公开(公告)号：EP0608927A2
公开(公告)日：1994-08-03
申请号：EP94200071.2
申请日：1994-01-13
申请人： State of Israel Ministry of Defence Raphael Armament Development Authority
发明人： Maytal, Ben-Zion
IPC分类号： F25B29/00 , F25B9/02 , A61B17/36
CPC分类号： F25B29/00 , A61B18/02 , A61B2017/00154 , A61B2018/00041 , A61B2018/0281 , A61B2018/0287 , A61F2007/0059 , F25B9/02
摘要： A method for creating a surface (13,20) having a fast changing temperature, comprises providing a heat exchanger (2) coupled to an orifice (3) opening into a jacket (4) which is in contact with the surface (13,20) to be heated and cooled, the said jacket (4) forming a reservoir capable of housing a fluid in contact with the surface (13,20) to be heated and cooled, and providing two gas sources, each gas source being independently connected to the said heat exchanger (2), one source providing a first gas, which liquefies when it expands through the said orifice (3), and the other gas source providing a second gas, having an inversion temperature lower than the temperature obtained by the liquefaction of the first gas, and causing the exhaust gas flowing out from the said jacket (4), to flow through the said heat-exchanger (2) to preheat or precool the inflowing gas, as the case may be, and further causing the said first and the said second gas alternately to flow through the said heat exchanger (2) and orifice (3), to cool or to heat the said surface (13,20); means (10,11) being provided for allowing and stopping the flow of each gas through the said orifice (3).
摘要翻译：一种用于创建表面具有几乎改变温度，方法包括提供在孔口开口联接到热交换器流入夹套的所有这是在与表面接触，以进行加热和冷却时，所述护套形成的贮存器能够容纳在流体中的与该表面接触，以进行加热和冷却，并提供两个气体源，每个燃气源是unabhängig连接到所述热交换器，一个源提供第一气体，该气体液化当其膨胀穿过所述孔，而另一个气体源提供一第二气体，具有转化温度比由所述第一气体的液化获得的温度下，以及使从所述护套流出，流过所述热交换器以预热或预冷流入的气体的排气，视情况而定，并且第一进一步使所述说和第二气体。所述可替换地通过热交换器和所述孔口流动，以冷却或加热。所述面传热 Ë; 装置被提供用于允许和通过孔口所述止动各气体的流动。

5. 发明授权

EP2593028B1 CRYOSURGICAL INSTRUMENT FOR TREATING LARGE VOLUME OF TISSUE 失效
标题翻译：治疗大体积组织的冷冻外科器械
公开(公告)号：EP2593028B1
公开(公告)日：2017-08-16
申请号：EP11754809.9
申请日：2011-09-01
申请人： Icecure Medical Ltd.
发明人： BERZAK, Nir , SHARON, Simon , HILLELI, Ron
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B5/7232 , A61B2018/0281 , A61B2018/0287 , A61B2018/0293

6. 发明授权

EP2696785B1 COILED HEAT EXCHANGER FOR CRYOSURGICAL INSTRUMENT 有权
标题翻译：盘管换热换取冷冻头器械
公开(公告)号：EP2696785B1
公开(公告)日：2016-11-02
申请号：EP11760933.9
申请日：2011-09-14
申请人： Icecure Medical Ltd.
发明人： BERZAK, Nir , HILLELI, Ron
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B18/0218 , A61B2018/0212 , A61B2018/0281 , A61B2018/0287 , A61B2018/0293
摘要： A cryosurgical instrument including: a shaft having a closed distal end defining an expansion chamber and an open proximal end adapted and configured to receive an inflow of cryogen and to exhaust a flow of expanded cryogen; and a heat exchanger. The heat exchanger includes: a plurality of cryogen delivery tubes that spiral around a longitudinal axis thereof; and a diffuser having a plurality of branches, each of the branches supplying received cryogen to a respective one of the delivery tubes. The cryogen delivery tubes, where they spiral, are spaced from each other and in fluid tight contact with the inner surface of the shaft so as to form spiraling cryogen exhaust pathways that extend along a portion of a length of the cryosurgical instrument from the distal end of the shaft.

7. 发明授权

EP1608281B1 APPARATUS FOR ACCURATELY DELIMITED CRYOABLATION 有权
标题翻译：设备进行准确有限公司冷冻消融
公开(公告)号：EP1608281B1
公开(公告)日：2016-07-13
申请号：EP04725137.6
申请日：2004-04-01
申请人： Galil Medical Ltd.
发明人： ZVULONI, Roni , AMIR, Uri
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B90/11 , A61B2018/00041 , A61B2018/0262 , A61B2018/0287 , A61B2018/0293

8. 发明公开

EP0919197A1 Device for trans myocardial cryo revascularization 有权
标题翻译：心肌血运重建低温
公开(公告)号：EP0919197A1
公开(公告)日：1999-06-02
申请号：EP98204029.7
申请日：1998-11-30
申请人： Galil Medical Ltd
发明人： Ammar, Rony , Bliweis, Mordechai , Ofer, Glinka , Sturlesi, Gideon, Even
IPC分类号： A61B17/36
CPC分类号： A61B18/02 , A61B2017/00243 , A61B2017/00247 , A61B2018/00392 , A61B2018/0287 , F25B2309/021
摘要： Cryosurgery method and device for performing trans myocardial revascularization are provided. The method includes: forming trans myocardial channels by cryoablating selected portions of the myocardial tissue. The cryosurgery device includes:(a) an operating member having an operating surface and a hollow; and a housing member connected thereto; (b) a first passageway extending along the device for providing high pressure gas to the operating member, the first passageway including a primary Joule Thomson heat exchanger in the form of a primary orifice located on the first passageway for enabling expansion of gas within the hollow of the operating member, thereby providing a desired temperature to the surface of the operating member; (c) a second passageway extending through the length of the housing member for evacuating gas from the operating tip to atmosphere; (d) a third passageway extending along a portion of the device and including a secondary Joule Thomson heat exchanger for providing a desired temperature to gas flowing through the first passageway. Method and device according to the present invention enable to form durable transmyocardial channels without causing considerable trauma to the myocardial tissue.

9. 发明公开

EP3302325A2 CRYOABLATION CATHETER HAVING AN ELLIPTICAL-SHAPED TREATMENT SECTION 审中-公开
标题翻译：具有椭圆形处理部分的冷冻导管
公开(公告)号：EP3302325A2
公开(公告)日：2018-04-11
申请号：EP16803999.8
申请日：2016-05-23
申请人： Adagio Medical, Inc.
发明人： YU, Xiaoyu , KOVALCHECK, Steven , CHIEN, Thomas , BABKIN, Alexei , KING, Nicolei
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2018/00041 , A61B2018/00214 , A61B2018/00351 , A61B2018/00357 , A61B2018/00404 , A61B2018/00577 , A61B2018/00642 , A61B2018/0212 , A61B2018/0262 , A61B2018/0268 , A61B2018/0287
摘要： A cryoablation catheter for creating at least one lesion in tissue, the catheter having an elongate shaft with an intermediate section and a distal tip movable relative to the intermediate section. The catheter also includes at least one elongate control member extending along the intermediate section and secured to the distal tip where the elongate control member is movable relative to the intermediate section for causing movement of the distal tip relative to the intermediate section and at least one energy delivery member extending along the intermediate section to the distal tip where the at least one energy delivery member includes a linear first configuration and an elliptical second configuration. Manipulation of the control member adjusts the shape of the at least one energy delivery member.

10. 发明公开

EP2967709A1 THERAPEUTIC CRYOABLATION SYSTEM 有权
标题翻译：治疗性冷冻系统
公开(公告)号：EP2967709A1
公开(公告)日：2016-01-20
申请号：EP14765232.5
申请日：2014-02-28
申请人： Cryofocus Medtech (Shanghai) Co., Ltd.
发明人： DUONG, Thach Buu , ZENG, Min Frank , LIU, Peng , XIN, Chaohua
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/00323 , A61B2018/00101 , A61B2018/0022 , A61B2018/00285 , A61B2018/00577 , A61B2018/0212 , A61B2018/0287
摘要： A cryoablation system has a gas source which provides a working nitrogen gas at room temperature and at a constant set pressure, a liquid generator which is coupled to the gas source to receive the working gas, and which then generates a working cryogen fluid, and a catheter coupled to the liquid generator for receiving the working cryogen, the catheter having a distal section having a freezing element which delivers the working cryogen to a treatment location, the catheter also having a balloon positioned adjacent the distal section.
摘要翻译：冷冻消融系统具有在室温和恒定设定压力下提供工作氮气的气体源，与气体源连接以接收工作气体并随后产生工作制冷剂流体的液体发生器，以及连接到液体发生器以接收工作冷冻剂的导管，导管具有远端部分，该远端部分具有将工作冷冻剂输送到治疗位置的冷冻元件，该导管还具有邻近远端部分定位的球囊。

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