专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明公开

EP2208734A1 FOOD MATERIAL FOR INHIBITING THE FORMATION OF OSTEOCLAST 有权转让
标题翻译：用于抑制骨关节炎形成的食物材料
公开(公告)号：EP2208734A1
公开(公告)日：2010-07-21
申请号：EP08844720.6
申请日：2008-10-28
申请人： Snow Brand Milk Products Co., Ltd.
发明人： SERIZAWA, Atsushi , MORITA, Yoshikazu , UETSUJI, Daisuke , ONO, Aiko , MATSUYAMA, Hiroaki , HIGURASHI, Satoshi
IPC分类号： C07K14/47 , A23K1/16 , A23L1/305 , A61K38/00 , A61P19/08 , C07K2/00
CPC分类号： C07K14/4703 , A21D2/263 , A21D13/80 , A23C19/082 , A23K20/147 , A23K50/40 , A23L2/02 , A23L2/52 , A23L33/19 , A23V2002/00 , A61K35/00 , A61K38/00 , A23V2250/032 , A23V2250/5424 , A23V2250/1578 , A23V2200/306 , A23V2250/5488 , A23V2250/5118 , A23V2250/70 , A23V2250/156 , A23V2250/5108 , A23V2250/54246 , A23V2250/0632 , A23V2250/628
摘要： Disclosed is an osteoclastogenesis inhibitory agent which comprises a milk protein fraction having the following properties (1) to (4) and the agent is excellent in an osteoclastogenesis inhibitory effect and useful for preventing or treating bone diseases:
(1) the milk protein fraction is derived from milk;
(2) the milk protein fraction is a fraction containing a protein having a molecular weight of 80,000 to 85,000 Daltons;
(3) the milk protein fraction has a basic amino acid content of 16 to 18 wt% in the constitutional amino acid composition, and the ratio of the amount of a basic amino acid(s) to the amount of an acidic amino acid(s) is 0.65 to 0.85; and
(4) the milk protein fraction has an osteoclastogenesis inhibitory effect .
摘要翻译：本发明公开了一种破骨细胞形成抑制剂，其包含具有以下性质（1）至（4）的乳蛋白质部分，并且该破骨细胞生成抑制效果优异并且可用于预防或治疗骨疾病：（1）乳蛋白质部分为来源于牛奶; （2）乳蛋白质级分是含有分子量为80,000至85,000道尔顿的蛋白质的级分; （3）构成氨基酸组合物中的乳蛋白质成分的碱性氨基酸含量为16〜18重量％，碱性氨基酸的量相对于酸性氨基酸的量的比例）为0.65至0.85; （4）乳蛋白质级分具有破骨细胞生成抑制作用。

2. 发明公开

EP1656948A1 OSTEOGENESIS PROMOTER 审中-公开
标题翻译：含有乳过氧化物酶用于预防或治疗骨质疏松症，骨折和腰痛中的组合物
公开(公告)号：EP1656948A1
公开(公告)日：2006-05-17
申请号：EP04771656.8
申请日：2004-08-13
申请人： SNOW BRAND MILK PRODUCTS, CO., LTD.
发明人： MOTOURI, Mutsumi , MATSUYAMA, Hiroaki , MORITA, Yoshikazu , SERIZAWA, Atsushi , KAWAKAMI, Hiroshi
IPC分类号： A61K38/44 , A61P19/08 , A23L1/30 , A23K1/165
CPC分类号： C12Y111/01007 , A23K20/189 , A23L33/19 , A23V2002/00 , A61K38/44 , A23V2250/5425 , A23V2200/306
摘要： It is intended to provide an osteogenesis promoter capable of promoting osteogenesis by promoting the differentiation of osteoblasts, and foods, drinks, drugs or feeds for promoting osteogenesis. Namely, an osteogenesis promoter capable of promoting osteogenesis by promoting the differentation of osteoblasts which comprises, as the active ingredient, lactoperoxidase and/or a digestion product obtained by digesting lactoperoxidase with a protease such as trypsin; and foods, drinks, drugs or feeds for promoting osteogenesis containing lactoperoxidase and/or its digestion product.
摘要翻译：它旨在通过宣传婷提供能够宣传片鼎成骨的骨形成促进成骨细胞，以及食品，饮料，药品的分化或促销廷成骨因子。即，在能够促销廷成骨通过促销婷成骨细胞的分化，其包含作为活性成分的乳过氧化物酶和/或消化乳过氧化物酶与蛋白酶获得的消化产物的骨形成促进剂：如胰蛋白酶; 而食品，饮料，药物或饲料的促销鼎成骨含有乳过氧化物酶和/或其消化产品。

3. 发明公开

EP2210507A1 BONE-STRENGTHENING FOOD MATERIAL 有权转让
标题翻译： ZUSAMMENSETZUNGEN ZURKNOCHENSTÄRKUNG
公开(公告)号：EP2210507A1
公开(公告)日：2010-07-28
申请号：EP08845996.1
申请日：2008-10-28
申请人： Snow Brand Milk Products Co., Ltd.
发明人： SERIZAWA, Atsushi , MORITA, Yoshikazu , UETSUJI, Daisuke , ONO, Aiko , MATSUYAMA, Hiroaki , HIGURASHI, Satoshi
IPC分类号： A23L1/305 , A23J1/20 , A23K1/16 , A61K38/00 , A61P19/08
CPC分类号： A61K35/20 , A21D2/263 , A23C19/082 , A23C19/0917 , A23J1/20 , A23L2/66 , A23L33/19 , A23V2002/00 , A23V2300/30 , A23V2200/306 , A23V2250/5424
摘要： Disclosed is a bone-reinforcing agent which comprises a milk protein fraction having the following properties (1) to (4): (1) the milk protein fraction is derived from milk; (2) the milk protein fraction is a fraction containing a protein component having a molecular weight of 6,000 to 150,000 Daltons; (3) the milk protein fraction has a basic amino acid content of 12 to 14 wt% in the constitutional amino acid composition, and the ratio of the amount of a basic amino acid(s) to the amount of an acidic amino acid(s) is 0.5 to 0.7; and (4) the milk protein fraction has an activity of accelerating the calcification in an osteoblast.
摘要翻译：公开了一种骨增强剂，其包含具有以下性质（1）至（4）的乳蛋白质级分：（1）乳蛋白质级分来自牛奶; （2）乳蛋白质级分是含有分子量为6,000至150,000道尔顿的蛋白质组分的级分; （3）在构成氨基酸组成中，乳蛋白质级分的碱性氨基酸含量为12〜14重量％，碱性氨基酸与酸性氨基酸量的比（s ）为0.5〜0.7; 和（4）乳蛋白级分具有加速成骨细胞钙化的活性。

4. 发明公开

EP2011500A1 FAT ACCUMULATION INHIBITOR 无效
标题翻译：化学发光二极管代谢综合征
公开(公告)号：EP2011500A1
公开(公告)日：2009-01-07
申请号：EP07741227.8
申请日：2007-04-06
申请人： Snow Brand Milk Products Co., Ltd.
发明人： TANAKA, Reo , ISOGAI, Tomoyuki , HARUTA, Yuko , MIURA, Susumu , KATO, Ken , YOSHIOKA, Toshimitsu , KAWAKAMI, Hiroshi , HIGURASHI, Satoshi , MATSUYAMA, Hiroaki
IPC分类号： A61K31/661 , A23L1/30 , A23L2/00 , A61K35/20 , A61P3/04
CPC分类号： A61K35/20 , A23L2/52 , A23L33/19 , A23V2002/00 , A61K31/661 , A23V2200/332 , A23V2250/1844
摘要： To provede a fat accumulation inhibitor and a food or drink for inhibiting fat accumulation, a visceral fat accumulation inhibitor and a food or drink for inhibiting visceral fat accumulation, or an agent for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood and a food or drink for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood.
A fat accumulation inhibitor for a fat cell, which comrises a milk-derived phospholipid as an active ingredient, and a food or drink for inhibiting fat accumulation in a fat cell, which comprises a milk-derived phospholipid. A visceral fat accumulation inhibitor comprising a sphingosine-containing phospholipid or a derivative thereof as an active ingredient, and a food or drink for inhibiting visceral fat accumulation. An agent for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood , which comprises a sphingosine-containing phospholipid or a derivative thereof as an active ingredient, and a food or drink for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood.
摘要翻译：证明脂肪蓄积抑制剂和用于抑制脂肪蓄积的食物或饮料，内脏脂肪蓄积抑制剂和用于抑制内脏脂肪蓄积的食品或饮料，或用于加速和/或抑制血液中脂联素浓度降低的试剂，以及用于加速和/或抑制血液中脂联素浓度降低的食物或饮料。一种脂肪蓄积抑制剂，其含有来自乳的磷脂作为活性成分的脂肪细胞，以及用于抑制脂肪细胞中的脂肪蓄积的食品或饮料，其包含乳源性磷脂。一种含有含鞘氨醇的磷脂或其衍生物作为活性成分的内脏脂肪蓄积抑制剂和抑制内脏脂肪蓄积的食品或饮料。用于促进增加和/或抑制血液中脂联素浓度降低的试剂，其包含含鞘氨醇的磷脂或其衍生物作为活性成分，以及用于加速和/或抑制脂联素浓度降低的食品或饮料在血液中

5. 发明公开

EP2133090A1 GROWTH HORMONE SECRETION STIMULATOR 审中-公开
标题翻译：生长激素分泌刺激因子
公开(公告)号：EP2133090A1
公开(公告)日：2009-12-16
申请号：EP08721754.3
申请日：2008-03-11
申请人： Snow Brand Milk Products Co., Ltd.
发明人： ONO, Aiko , MATSUYAMA, Hiroaki , MORITA, Yoshikazu , SERIZAWA, Atsushi , HIGURASHI, Satoshi
IPC分类号： A61K38/00 , A61P5/06
CPC分类号： A61K38/018 , A23L2/52 , A23L2/66 , A23L33/19
摘要： Provided are: an agent for promoting growth hormone-secretion, containing a milk-derived basic protein fraction as an active ingredient, with the promotion of growth hormone-secretion being mediated by the promotion of secretion of ghrelin having an effect for promoting growth hormone-secretion; and a method of promoting the secretion of ghrelin by using a milk-derived basic protein fraction. The agent for promoting growth hormone-secretion may be ingested on a daily basis and is highly safe even with its ingestion for a long period.
摘要翻译：本发明提供一种生长激素分泌促进剂，其含有源自乳源的碱性蛋白质级分作为有效成分，促进生长激素分泌，其通过促进具有促进生长激素分泌作用的生长素释放肽的分泌来介导，分泌; 以及使用乳来源的碱性蛋白质级分来促进生长素释放肽的分泌的方法。促进生长激素分泌的药剂可以每天摄取，并且即使长时间摄取也是高度安全的。

6. 发明公开

EP1669084A1 AGENT FOR PROMOTING OSTEOGENESIS AND/OR INHIBITING BONE RESORPTION 审中-公开
标题翻译： MITTEL ZURFÖRDERUNGDER OSTEOGENESE UND / ODER ZUR HEMMUNG DER KNOCHENRESORPTION
公开(公告)号：EP1669084A1
公开(公告)日：2006-06-14
申请号：EP04773639.2
申请日：2004-09-30
申请人： SNOW BRAND MILK PRODUCTS CO., LTD.
发明人： MORITA, Yoshikazu , SERIZAWA, Atsushi , MATSUYAMA, Hiroaki , MOTOURI, Mutsumi , KAWAKAMI, Hiroshi
IPC分类号： A61K38/16 , A61K38/36 , A61K38/01 , A61P19/08 , A61P19/10 , A23L1/305 , A23K1/16
CPC分类号： A61K38/1729 , A23K20/147 , A23K20/189 , A23L33/17 , A61K38/1725
摘要： Provided is a novel agent for promoting osteogenesis and/or inhibiting bone resorption, which: can be directly taken from daily meals by mouth for long periods without any trouble in taste; directly impart a promoting effect on osteogenesis and an inhibiting effect on bone resorption to the bone; and can be expected to have therapeutic effects for preventing or ameliorating/treating various bone diseases. The above agent includes, as an active ingredient, any one or more of β 2 -microglobulin, histone, complement component 3, monocyte chemotactic protein1, lysozyme, ribonuclease, prothrombin, cytochrome P-450, plasminogen, transferrin, thrombin, plasmin, complement component 4, and β defensin, and enzymatic digestion products thereof. Those substances have a remarkable inhibiting effect on bone resorption by osteoclasts and/or a promoting effect on osteogenesis via promotion of the proliferation and differentiation of osteoblasts.
摘要翻译：提供促进骨吸收和/或抑制骨吸收的新型药剂，其可以直接从日常饮食中口服长时间，没有任何麻烦的味道; 直接对骨骼发生促进作用，对骨吸收骨骼具有抑制作用; 并且可以预期具有预防或改善/治疗各种骨疾病的治疗效果。上述药剂包括作为活性成分的任何一种或多种的2-微球蛋白，组蛋白，补体成分3，单核细胞趋化蛋白1，溶菌酶，核糖核酸酶，凝血酶原，细胞色素P-450，纤溶酶原，转铁蛋白，凝血酶，纤溶酶，补体组分4和²防御素及其酶消化产物。这些物质通过促进成骨细胞的增殖和分化对破骨细胞的骨吸收和/或对成骨的促进作用具有显着的抑制作用。

7. 发明公开

EP2039365A1 VISCERAL FAT ACCUMULATION INHIBITOR, AND AGENT FOR PROMOTING THE INCREASE IN AND/OR INHIBITING THE DECREASE IN BLOOD ADIPONECTIN LEVEL 无效
标题翻译：内脏脂肪收集的抑制剂，推广手段的兴起和/或减少异径脂联素镜的血
公开(公告)号：EP2039365A1
公开(公告)日：2009-03-25
申请号：EP07737233.2
申请日：2007-05-30
申请人： Snow Brand Milk Products Co., Ltd.
发明人： KAWAKAMI, Hiroshi , HIGURASHI, Satoshi , MATSUYAMA, Hiroaki
IPC分类号： A61K35/20 , A23C17/00 , A23L1/30 , A61P3/00 , A61P3/04
CPC分类号： A61K35/35 , A23C2240/05 , A23L2/02 , A23L33/10 , A23L33/20
摘要： Disclosed is: a visceral fat accumulation inhibitor or a food or drink for inhibiting the accumulation of a visceral fat, which composes a fat globule membrane component as an active ingredient; or a agent or food or drink for promoting the increase in the blood adiponection level and/or inhibiting the decrease in the blood adiponection level, which composes a fat globule membrane component as an active ingredient. A fat globule membrane component can inhibit the accumulation of a visceral fat, and/or can promote the increase in or inhibit the decrease in the blood adiponection level.

8. 发明公开

EP2208735A1 FOOD MATERIAL FOR PROMOTING THE DIFFERENTIATION OF OSTEOBLAST AND INHIBITING THE DIFFERENTIATION OF OSTEOCLAST 有权
标题翻译：食物以促进成骨细胞分化和破骨细胞的分化INHIBITING
公开(公告)号：EP2208735A1
公开(公告)日：2010-07-21
申请号：EP08846202.3
申请日：2008-10-28
申请人： Snow Brand Milk Products Co., Ltd.
发明人： SERIZAWA, Atsushi , MORITA, Yoshikazu , UETSUJI, Daisuke , ONO, Aiko , MATSUYAMA, Hiroaki , HIGURASHI, Satoshi
IPC分类号： C07K14/47 , A23K1/16 , A23L1/305 , A61K38/00 , A61P19/08 , C07K2/00
CPC分类号： A23K50/40 , A21D2/263 , A23C19/082 , A23J1/20 , A23J3/08 , A23K20/147 , A23L2/66 , A23L33/19 , A23V2002/00 , A61K35/20 , A61K38/018 , C07K14/47 , A23V2200/306 , A23V2250/5424
摘要： Disclosed is an osteoblast differentiation promoting and osteoclast differentiation inhibiting agent which comprises a milk protein fraction having the following characteristics (1) to (4): (1) the milk protein fraction is derived from milk; (2) the milk protein fraction is a fraction containing a protein component having a molecular weight of 75,000 to 85,000 Daltons; (3) the milk protein fraction has a basic amino acid content of 13 to 15 wt% in the constitutional amino acid composition, and has a basic amino acid/acidic amino acid of 0.5 to 0.7; and (4) the milk protein fraction has an osteoblast differentiation promoting effect and an osteoclast differentiation inhibiting.
摘要翻译：公开的是，其包括具有以下特性的乳蛋白质级分的成骨细胞分化的促销廷和破骨细胞分化抑制剂（1）至（4）：（1）乳蛋白质级分为乳来源; （2）乳蛋白质级分是包含具有75,000〜85,000道尔顿的分子量的蛋白质成分的级分; （3）的乳蛋白质级分具有在构成氨基酸组成的13的碱性氨基酸含量至15重量％，并且具有0.5至0.7的碱性氨基酸/酸性氨基酸; 和（4）的乳蛋白质级分具有上成骨细胞分化的促销效果廷和破骨细胞分化抑制。

9. 发明公开

EP2208733A1 FOOD MATERIAL FOR INHIBITING BONE RESORPTION 审中-公开
标题翻译： NAHRUNGSMITTEL ZUR INHIBIERUNG VON KNOCHENRESORPTION
公开(公告)号：EP2208733A1
公开(公告)日：2010-07-21
申请号：EP08843536.7
申请日：2008-10-28
申请人： Snow Brand Milk Products Co., Ltd.
发明人： SERIZAWA, Atsushi , MORITA, Yoshikazu , UETSUJI, Daisuke , ONO, Aiko , MATSUYAMA, Hiroaki , HIGURASHI, Satoshi
IPC分类号： C07K14/47 , A23K1/16 , A23L1/305 , A61K38/00 , A61P19/08 , C07K2/00
CPC分类号： A23K50/40 , A21D2/263 , A23C19/082 , A23J1/20 , A23J3/343 , A23K20/147 , A23L2/395 , A23L2/66 , A23L33/19 , A23V2002/00 , A61K35/20 , C07K14/4703 , A23V2250/5424 , A23V2200/306
摘要： A milk protein fraction having following properties (1) to (4) is excellent in bone resorption inhibitory effect, and is useful for preventing or treating bone diseases:
(1) the milk protein fraction is derived from milk;
(2) the milk protein fraction is a fraction containing a protein having a molecular weight of 12,000 to 16,000 Daltons;
(3) the milk protein fraction has a basic amino acid content of 18 to 20 wt% in the constitutional amino acid composition, and the ratio of the amount of a basic amino acid(s) to the amount of an acidic amino acid(s) is 0.7 to 0.9; and
(4) the milk protein fraction has a bone resorption inhibitory effect.
摘要翻译：具有以下特性（1）〜（4）的乳蛋白质级分骨吸收抑制效果优异，可用于预防或治疗骨病：（1）乳蛋白质分数来自牛奶; （2）乳蛋白质级分是含有分子量为12,000至16,000道尔顿的蛋白质的级分; （3）在构成氨基酸组成中，乳蛋白质级分的碱性氨基酸含量为18〜20重量％，碱性氨基酸的量与酸性氨基酸的量（s ）为0.7〜0.9; 和（4）乳蛋白质分数具有骨吸收抑制作用。

10. 发明公开

EP2062587A1 AGENT FOR ACCELERATING THE INCREASE IN AND/OR PREVENTING THE DECREASE IN BLOOD ADIPONECTIN LEVEL, AND VISCERAL FAT ACCUMULATION INHIBITOR 审中-公开
标题翻译：代理加速度的突显和/或防止脂联素血与镜内脏脂肪蓄积抑制剂的沉没
公开(公告)号：EP2062587A1
公开(公告)日：2009-05-27
申请号：EP07805787.4
申请日：2007-08-30
申请人： Snow Brand Milk Products Co., Ltd.
发明人： KAWAKAMI, Hiroshi , HIGURASHI, Satoshi , MATSUYAMA, Hiroaki
IPC分类号： A61K35/74 , A23K1/16 , A23L1/30 , A61P3/06
CPC分类号： A23C9/1234 , A23C19/0323 , A23K10/16 , A23K10/18 , A23K50/40 , A23L2/52 , A23L33/135 , A23V2002/00 , A23Y2220/37 , A23Y2220/39 , A61K35/747 , A23V2250/064 , A23V2200/332
摘要： Disclosed is an agent for accelerating the increase in and/or preventing the decrease in the blood adiponectin level, or a food, beverage or animal feed for accelerating the increase in and/or preventing the decrease in the blood adiponectin level, which comprises a culture or cell of a lactic acid bacterium belonging to the genus Lactobacillus, particularly Lactobacillus gasseri or Lactobacillus helveticus as an active ingredient. Also disclosed is a visceral fat accumulation inhibitor or a food or beverage for inhibiting the accumulation of a visceral fat, which comprises a culture or cell of Lactobacillus helveticus as an active ingredient.
摘要翻译：公开了一种用于加速的增加和/或预防血液中脂连蛋白浓度的降低，或用于加速增加和/或预防血液中脂连蛋白浓度的降低，该方法包括培养物的食品，饮料或饲料的试剂还是属于乳杆菌属，特别是加氏乳杆菌或瑞士乳杆菌作为活性成分的乳酸菌的细胞。游离缺失所以盘是内脏脂肪蓄积抑制剂或用于抑制内脏脂肪的蓄积，其包括瑞士乳杆菌的培养物或细胞作为活性成分的食品或饮料。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式