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1. 发明公开

EP3305086A1 LACTIC ACID BACTERIUM-CONTAINING FAT OR OIL COMPOSITION AND METHOD FOR MANUFACTURING SAME 审中-公开
标题翻译：含有乳酸菌的脂肪或油组合物及其制造方法
公开(公告)号：EP3305086A1
公开(公告)日：2018-04-11
申请号：EP16802806.6
申请日：2016-05-31
申请人： Lotte Co., Ltd. , Nitto Pharmaceutical Industries, Ltd.
发明人： ASHITANI, Hiroaki , KOYAMA, Toshiyuki , USAMIKRANK, Yoko , ISHIZUKA, Tomokazu , TADOKORO, Keiji , KABUKI, Yusuke , YONEJIMA, Yasunori , HISA, Keiko
IPC分类号： A23G1/00 , A23G1/30 , A23L33/10
CPC分类号： A23L33/135 , A23G1/305 , A23G1/40 , A23G1/423 , A23G2200/02 , A23L33/10 , A23V2002/00 , A23V2200/3204 , A23Y2220/03 , A23Y2220/13 , A23Y2220/37 , A23Y2240/33 , A23Y2260/35 , A23Y2300/55
摘要： By adding a viable lactic acid bacterium to a fat or oil composition, the present invention has succeeded in producing a lactic acid bacterium-containing fat or oil composition that has a high viability of the lactic acid bacterium and an excellent resistance to acids. By adding lactic acid bacteria powder or a chocolate with a high lactic acid bacterium concentration to a chocolate dough after tempering and before molding, moreover, the present invention has succeeded in producing a lactic acid bacterium-containing chocolate including a viable lactic acid bacterium by a simple producing method. Thus, provided is a lactic acid bacterium-containing chocolate with high palatability that contains a viable lactic acid bacterium.
摘要翻译：通过在油脂组合物中添加活性乳酸菌，本发明成功地制造了乳酸菌的活力高，耐酸性优异的含有乳酸菌的油脂组合物。另外，本发明通过在回火后且成型前向巧克力面团中添加乳酸菌粉末或乳酸菌浓度高的巧克力，从而成功地制造了包含活性乳酸菌的含有乳酸菌的巧克力，简单的生产方法。因此，提供了含有活乳酸菌的适口性高的含有乳酸菌的巧克力。

2. 发明授权

EP2415858B1 METHOD FOR PRODUCING FERMENTED MILK 有权
标题翻译：生产发酵乳的方法
公开(公告)号：EP2415858B1
公开(公告)日：2017-08-23
申请号：EP10758587.9
申请日：2010-03-26
申请人： Meiji Co., Ltd.
发明人： ISAWA, Kakuhei , KAMIJO, Masayuki
IPC分类号： C12N1/20 , A23C9/123 , A23L3/3463
CPC分类号： A23C9/1234 , A23L3/3463 , A23L3/34635 , A23Y2220/37 , C12N1/20 , C12N1/38

3. 发明公开

EP3011966A1 Compositions for the inhibition of Giardia Lamblia 审中-公开
标题翻译： Zusammensetzungen zur Hemmung von Giardia Lamblia
公开(公告)号：EP3011966A1
公开(公告)日：2016-04-27
申请号：EP14306265.1
申请日：2014-08-08
申请人： INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE , MUSEUM NATIONAL D'HISTOIRE NATURELLE
发明人： Bermudez-Hiumaran, Luis G. , Allain, Thibault , Florent, Isabelle , Langella, Philippe , Grellier, Philippe , Travers, Marie-Agnès
IPC分类号： A61K38/00 , A23L33/10 , A61K38/16 , A61K38/46 , A61K35/74 , A61P33/02 , C07K14/335 , C12N15/74
CPC分类号： A61K38/50 , A23L33/135 , A23V2002/00 , A23Y2220/03 , A23Y2220/37 , A23Y2220/43 , A61K35/741 , A61K35/744 , A61K38/00 , A61K38/164 , A61K38/46 , C12N9/80 , C12Y305/01024 , Y02A50/491
摘要： The present invention relates to a composition exhibiting a bile-salt hydrolase activity for its use for the treatment or the prevention of giardiasis, said composition comprising a bile-salt hydrolase (BSH) enzyme, a bacterium able to secrete a BSH, a recombinant host cell able to secrete a BSH, or a combination thereof. The present invention also relates to the use of a composition exhibiting a BSH activity for the treatment or the prevention of giardiasis, and to a pharmaceutical composition or a food composition comprising, as an active principle, a BSH, a lactic acid bacterium able to secrete a BSH, or a recombinant host cell able to secrete a BSH.
摘要翻译：本发明涉及一种显示出用于治疗或预防贾霸病的胆汁盐水解酶活性的组合物，所述组合物包含胆汁盐水解酶（BSH）酶，能够分泌BSH的细菌，重组宿主能够分泌BSH的细胞或其组合。本发明还涉及显示BSH活性的组合物用于治疗或预防贾霸病的用途，以及包含作为活性成分的BSH，能够分泌的乳酸菌的药物组合物或食品组合物的用途 BSH或能够分泌BSH的重组宿主细胞。

4. 发明公开

EP2415858A1 METHOD FOR CULTURING LACTIC ACID BACTERIUM AND METHOD FOR PRODUCING FERMENTED MILK 有权
标题翻译： VERFAHREN ZUR HERSTELLUNG FERMENTIERTER MILCH
公开(公告)号：EP2415858A1
公开(公告)日：2012-02-08
申请号：EP10758587.9
申请日：2010-03-26
申请人： Meiji Co., Ltd.
发明人： ISAWA, Kakuhei , KAMIJO, Masayuki
IPC分类号： C12N1/20 , A23C9/123
CPC分类号： A23C9/1234 , A23L3/3463 , A23L3/34635 , A23Y2220/37 , C12N1/20 , C12N1/38
摘要： Protein in an aqueous whey solution is degraded by adding a protease to the aqueous whey solution. After that, a whey degradation medium is prepared by adding yeast extract or the like to the aqueous whey solution. The whey degradation medium is inoculated with bacteriocin-producing lactic acid bacterium and the lactic acid bacterium is cultured while the whey degradation medium is maintained at pH of not lower than 5 and not higher than 6. After the completion of the culture, the whey degradation medium (culture solution) is centrifuged to thereby separate a concentrated cell suspension containing the lactic acid bacterium in a concentrated form. The concentrated cell suspension has extremely high antibacterial activity (several tens of thousands AU) and is usable as a food preservative. Further, yogurt is produced by fermenting a yogurt mix to which 0.01% to 0.1% by weight of the concentrated cell suspension is added. With this process, it is possible to suppress an increase in the acidity of the yogurt.
摘要翻译：乳清水溶液中的蛋白质通过向乳清水溶液中加入蛋白酶来降解。之后，通过向乳清水溶液中添加酵母提取物等来制备乳清分解培养基。用细菌素生产乳酸菌接种乳清分解培养基，培养乳酸菌，同时乳清分解培养基保持在不低于5且不高于6的pH。培养完成后，乳清降解将培养液（培养液）离心分离出浓缩形式的含有乳酸菌的浓缩细胞悬浮液。浓缩的细胞悬浮液具有极高的抗菌活性（几万AU），可用作食品防腐剂。此外，通过发酵添加浓缩的细胞悬浮液的0.01重量％至0.1重量％的酸奶混合物来生产酸奶。通过该方法，可以抑制酸奶的酸度的增加。

6. 发明公开

EP2046943A1 LACTIC ACID BACTERIA ISOLATED FROM MOTHER'S MILK WITH PROBIOTIC ACTIVITY AND INHIBITORY ACTIVITY AGAINST BODY WEIGHT AUGMENTATION 有权
标题翻译：从益生菌活性和抑制活性体重增加乳腺癌牛奶分离乳酸菌
公开(公告)号：EP2046943A1
公开(公告)日：2009-04-15
申请号：EP07746512.8
申请日：2007-05-14
申请人： Bioneer Corporation
发明人： KANG, Ji Hee , YOU, Byeung Il , YUN, Sung Il , PARK, Han Oh
IPC分类号： C12N1/20
CPC分类号： C12R1/225 , A23C9/1234 , A23L33/135 , A23L33/18 , A23Y2220/37 , A61K38/00 , C07K14/335 , C12N1/20
摘要： The present invention relates to a lactic acid bacterium isolated from human mother's milk, more precisely a Lactobacillus gasseri BNR17 strain that is isolated from Korean mother's milk and has excellent probiotic activity including acid resistance, bile acid resistance and antimicrobial activity and weight gaining inhibitory effect as well. Again, the Lactobacillus gasseri BNR17 of the present invention has excellent acid resistance, bile acid resistance, enteric absorption activity and antimicrobial activity against pathogenic microorganisms, in addition to the weight gaining inhibitory effect by synthesizing indigestible polysaccharides from monosaccharides included in food taken and releasing the synthesized polysaccharides out of the body. Therefore, the strain of the invention, owing to such beneficiary effects, can be effectively used not only for the production of fermented milk, other fermented food products and animal feeds but also for the production of live cell products and food additives for preventing weight gaining.

7. 发明公开

EP1112692A4 DRINKS AND FOODS CAPABLE OF ELIMINATING HELICOBACTER PYLORI 有权
标题翻译：饮料和食物适于消除我幽门螺杆菌
公开(公告)号：EP1112692A4
公开(公告)日：2002-02-27
申请号：EP00900868
申请日：2000-01-21
申请人： MEIJI MILK PRODUCTS COMPANY LT , WAKAMOTO PHARMA CO LTD
发明人： KIMURA KATSUNORI , HIRATA HARUHISA , KOGA YASUHIRO
IPC分类号： A23C9/12 , A23C9/123 , A23L1/03 , A23L1/28 , A23L1/30 , A23L2/38 , A61K31/00 , A61K35/74 , A61P1/00 , A61P1/02 , A61P31/00 , A61P31/04 , C12N1/20 , C12R1/225
CPC分类号： C12R1/225 , A23C9/1234 , A23L29/065 , A23L33/10 , A23V2002/00 , A23Y2220/37 , A61K35/747 , A23V2200/10 , A23V2250/206
摘要： Drinks and foods for eliminating Helicobacter pylori and/or preventing the infection therewith which contain as the active ingredient Lactobacillus gasseri OLL2716 (FERM BP-6999) having a potent ability to eliminate H. pylori. Drinks and foods (acid milk, etc.) prepared by using the above lactic acid bacterium can be appropriately taken over a long time as food products for eliminating H. pylori and/or preventing the infection therewith.

8. 发明授权

EP2338976B1 LACTIC ACID BACTERIUM HAVING HIGH OXALIC ACID DECOMPOSITION ABILITY 有权转让
标题翻译：具有高酸性分解能力的乳酸菌
公开(公告)号：EP2338976B1
公开(公告)日：2017-08-16
申请号：EP09817746.2
申请日：2009-09-29
申请人： Meiji Co., Ltd.
发明人： OCHI, Daisuke , TSUBOI, Hiroshi
IPC分类号： C12N1/20 , A61K35/74 , A61P3/00 , A61P7/06 , A61P13/04 , A61P13/12 , A61P19/10 , C12R1/225
CPC分类号： A61K35/74 , A23L33/135 , A23V2002/00 , A23Y2220/37 , C12R1/225 , A23V2200/306
摘要： The present invention provides lactic acid bacteria having oxalic acid-degrading activity several times higher than those of conventionally known lactic acid bacteria having an oxalic acid-degrading activity, and uses thereof. Lactic acid bacteria capable of degrading a large amount of oxalic acid were screened from 132 strains of Lactobacillus lactic acid bacteria that have been independently isolated from feces and gastric juices of human adults. As a result, lactic acid bacteria having an oxalic acid degradation rate of 50% or more when cultured at 37°C for 72 hours in a culture medium containing 10 mM oxalic acid at pH 6.5 at the start of culture were discovered.
摘要翻译：本发明提供具有比现有公知的具有草酸分解活性的乳酸菌高几倍的草酸分解活性的乳酸菌及其用途。从132株乳酸杆菌乳酸菌中筛选出能够降解大量草酸的乳酸菌，这些乳酸菌已经从成人的粪便和胃液中独立分离。结果，发现在培养开始时在含有10mM草酸，pH6.5的培养基中于37℃培养72小时时，草酸分解率为50％以上的乳酸菌。

9. 发明公开

EP3177306A1 COMPOSITIONS FOR THE INHIBITION OF GIARDIA LAMBLIA 有权转让
标题翻译：抑制小菜蛾的组合物
公开(公告)号：EP3177306A1
公开(公告)日：2017-06-14
申请号：EP15750388.9
申请日：2015-08-10
申请人： Institut National de la Recherche Agronomique (INRA) , MUSEUM NATIONAL D'HISTOIRE NATURELLE , Ecole Nationale Vétérinaire D'Alfort
发明人： BERMUDEZ-HUMARAN, Luis G. , ALLAIN, Thibault , FLORENT, Isabelle , LANGELLA, Philippe , GRELLIER, Philippe , TRAVERS, Marie-Agnès , POLACK, Bruno
IPC分类号： A61K38/00 , A61K38/16 , A61K38/46 , A61K35/74 , A61P33/02 , C07K14/335 , C12N15/74 , A61K35/741 , A61K35/744
CPC分类号： A61K38/50 , A23L33/135 , A23V2002/00 , A23Y2220/03 , A23Y2220/37 , A23Y2220/43 , A61K35/741 , A61K35/744 , A61K38/00 , A61K38/164 , A61K38/46 , C12N9/80 , C12Y305/01024 , Y02A50/491
摘要： The present invention relates to a composition exhibiting a bile-salt hydrolase activity for its use for the treatment or the prevention of giardiasis, said composition comprising a bile-salt hydrolase (BSH) enzyme, a bacterium able to secrete a BSH, a recombinant host cell able to secrete a BSH, or a combination thereof. The present invention also relates to the use of a composition exhibiting a BSH activity for the treatment or the prevention of giardiasis, and to a pharmaceutical composition or a food composition comprising, as an active principle, a BSH, a lactic acid bacterium able to secrete a BSH, or a recombinant host cell able to secrete a BSH.
摘要翻译：本发明涉及显示胆盐水解酶活性的组合物用于治疗或预防贾第虫病，所述组合物包含胆盐水解酶（BSH）酶，能够分泌BSH的细菌，重组宿主细胞能够分泌BSH或其组合。本发明还涉及显示BSH活性的组合物用于治疗或预防贾第虫病的用途，并且涉及包含作为活性成分的BSH，能够分泌乳酸菌的药物组合物或食物组合物 BSH或能够分泌BSH的重组宿主细胞。

10. 发明公开

EP2923704A1 STRESS-INDUCED BOWEL DISORDER-RELIEVING AGENT COMPRISING SPECIFIC LACTOBACILLUS GASSERI STRAIN OR TREATMENT PRODUCT THEREOF 有权转让
标题翻译：手段与压力有关的疾病与特定的乳酸菌肠半月部落或任何处理产物RELIEF
公开(公告)号：EP2923704A1
公开(公告)日：2015-09-30
申请号：EP13854909.2
申请日：2013-11-15
申请人： Calpis Co., Ltd.
发明人： SAWADA Daisuke , FUJIWARA Shigeru
IPC分类号： A61K35/74 , A23K1/16 , A23L1/30 , A61P1/04 , A61P1/12 , A61P25/02 , C12N1/20 , C12R1/245
CPC分类号： A61K35/747 , A23K10/16 , A23K10/18 , A23L2/52 , A23L33/135 , A23V2002/00 , A23Y2220/37 , A61K9/0056 , A61K2035/115 , C12N1/20 , C12R1/225 , A23V2200/32
摘要： The present application provides Lactobacillus gasseri CP2305 strain (FERM BP-11331), Lactobacillus gasseri CP2305s strain (NITE BP-1405), or, a derivative strain (for example, a cold-tolerant derivative strain) derived from Lactobacillus gasseri CP2305 strain (FERM BP-11331) or the CP2305s strain, a method for producing the same, a stress-induced bowel disorder-alleviating agent comprising the derivative strain, a treated product thereof, or a mixture thereof as an active ingredient, and food additives, animal additives, animal feeds, and pharmaceutical compositions containing the agent.
摘要翻译：本申请提供了加氏乳杆菌CP2305株（FERM BP-11331），格氏乳杆菌CP2305s株（NITE BP-1405），或，衍生菌株（例如，冷耐受性衍生物株）从加氏乳杆菌CP2305株（FERM BP-11331）或CP2305s应变，其制造方法，应力诱发的肠功能障碍减轻剂，其包含的衍生菌株，其处理的产物，或它们的混合物作为活性成分的，和食品添加剂，动物添加剂，动物饲料，以及含有该药剂的药物组合物。

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