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1. 发明授权

EP1344539B1 Protector for percutaneous entries 有权
标题翻译：帽穿刺点
公开(公告)号：EP1344539B1
公开(公告)日：2007-08-29
申请号：EP03005686.5
申请日：2003-03-13
申请人： SUN MEDICAL TECHNOLOGY RESEARCH CORPORATION
发明人： Yamazaki, Kenji , Aizawa, Nobuaki
IPC分类号： A61M1/00 , A61M25/02 , A61M1/12 , A61M35/00
CPC分类号： A61M39/0247 , A61M1/1006 , A61M1/1008 , A61M1/101 , A61M1/12 , A61M1/122 , A61M1/127 , A61M1/14 , A61M1/28 , A61M25/02 , A61M2025/0246 , A61M2025/0266 , A61M2025/0273 , A61M2039/0288 , A61M2205/7518

2. 发明公开

EP1525892A2 Artificial blood vessel system, connecting assist tool and blood pump system 审中-公开
标题翻译： KünstlichesBlutgefä，Anschlusswerkzeug und Blutpumpsystem
公开(公告)号：EP1525892A2
公开(公告)日：2005-04-27
申请号：EP04025182.9
申请日：2004-10-22
申请人： SUN MEDICAL TECHNOLOGY RESEARCH CORPORATION
发明人： Yamazaki, Kenji , Kitano, Tomoya , Nakayama, Takeshi
IPC分类号： A61M1/10
CPC分类号： A61M39/12 , A61M1/1008 , A61M1/101 , A61M1/12 , A61M1/122 , A61M1/3653 , A61M1/3659 , A61M2205/04 , F16L33/225
摘要： The present invention provides an artificial blood vessel system which can suppress the occurrence of the stagnation of a blood flow and, eventually, the occurrence of the thrombus, can enhance the reliability of the connection, and can prolong the lifetime of the artificial blood connecting structure. In the artificial blood vessel system which includes an artificial blood vessel, a tubular connecting member which is connected with the artificial blood vessel, and connecting assist means for strengthening the connection between the artificial blood vessel and the tubular connecting member, the connecting assist means is configured to be capable of bringing the artificial blood vessel into pressure contact with the tubular connecting member not only along the radial direction of the tubular connecting member but also at an artificial-blood-vessel-side distal end of the tubular connecting member.
摘要翻译：本发明提供一种能够抑制血流停滞的发生，最终发生血栓的人造血管系统，能够提高连接的可靠性，能够延长人造血液连接结构的寿命。在包括人造血管（120）的人造血管系统中，与人工血管（120）连接的管状连接部件（110A，110B）以及连接辅助装置（130A，130B，230A，230A 2，230B 1，230B 2，330A，330B，430），用于加强人造血管（120）和管状连接构件（110A，110B）之间的连接，连接辅助装置（130A，130B，230A 1，230A 2，230B 1，230B 2，330A，330B，430）构造成能够使人造血管（120）不仅沿着管状的径向方向与管状连接构件（110A，110B）压力接触连接构件，而且在管状连接构件的人造血管侧远端。

3. 发明公开

EP1285671A2 Blood pump and ventricular assist device 审中-公开
标题翻译： Blutpumpe und Herzkammer-unterstützungsgerät
公开(公告)号：EP1285671A2
公开(公告)日：2003-02-26
申请号：EP02017795.2
申请日：2002-08-12
申请人： SUN MEDICAL TECHNOLOGY RESEARCH CORPORATION
发明人： Yamazaki, Kenji
IPC分类号： A61M1/10 , A61L17/04 , A61L17/10 , A61L27/06 , A61L31/02 , A61L33/08 , A61L33/12 , A61L33/18
CPC分类号： A61L31/022 , A61L33/022 , A61M1/1008 , A61M1/101 , A61M1/122 , A61M1/3673 , Y10S415/90
摘要： The blood pump (10) according to the present invention comprises a casing (20) having a blood inlet (16) and a blood outlet (18), and an impeller (22) for circulating blood by rotating inside the casing (20), wherein both the casing's and the impeller's surfaces in contact with blood are formed of a biocompatible metal, and onto the surfaces in contact with blood a coating film of a hemocompatible material comprising a phospholipid polymer is formed. According to the present invention, the blood pump (10) effectively suppresses the development of thrombi without activating blood coagulation factors such as thrombocites (blood platelets) in the blood, thanks to a coating film of a hemocompatible material made of a phospholipid polymer being formed onto the surfaces in contact with blood of the casing (20) and the impeller (22) composing the main part of the blood pump.
摘要翻译：根据本发明的血泵（10）包括具有血液入口（16）和血液出口（18）的壳体（20）和用于通过在壳体（20）内旋转来使血液循环的叶轮（22）其中壳体和与血液接触的叶轮表面均由生物相容性金属形成，并且在与血液接触的表面上形成包含磷脂聚合物的血液相容性材料的涂膜。根据本发明，由于形成了由磷脂聚合物形成的血液相容性材料的涂膜，血泵（10）能够有效地抑制血液的发生，而不会引起血液中血栓形成（血小板）等凝血因子在与壳体（20）的血液和构成血液泵的主要部分的叶轮（22）接触的表面上。

4. 发明公开

EP0659443A1 Sealing system of an artificial internal organ 失效
标题翻译： Dichtungssystemfüreinkünstlichesinneres Organ。
公开(公告)号：EP0659443A1
公开(公告)日：1995-06-28
申请号：EP94120619.5
申请日：1994-12-23
申请人： SUN MEDICAL TECHNOLOGY RESEARCH CORPORATION
发明人： Yamazaki, Kenji , Mori, Toshio
IPC分类号： A61L33/00 , A61M1/10
CPC分类号： A61L33/0047 , A61L33/128 , A61M1/101 , A61M1/1013 , A61M1/1017 , A61M1/102 , A61M1/1025 , A61M1/1031 , A61M1/122 , A61M1/125
摘要： An artificial internal organ, such as an artificial heart, comprising a pump unit (4) through which blood circulates and a drive shaft (10) for driving the pump unit, the drive shaft having a shaft sealing system (22, 27) thereon. The shaft sealing system is supplied with a sealing solution from a sealing solution chamber (21) and a sealing solution bag (12). The sealing solution is formed mainly of a physiological saline, which is loaded with a protease or several kinds of aminopeptides. When blood gets into the shaft sealing system (22, 27), it is prevented from coagulating by these admixtures. Although blood in the shaft sealing system (22, 27) of this type coagulates in a unique mechanism different from a conventional one, the protease and the aminopeptides never lose their effects even in such a unique situation.
摘要翻译：诸如人造心脏的人造内脏器官，包括血液循环的泵单元（4）和用于驱动泵单元的驱动轴（10），所述驱动轴具有轴密封系统（22,27）。轴密封系统由密封溶液室（21）和密封溶液袋（12）提供密封溶液。密封溶液主要由生理盐水形成，其装载有蛋白酶或几种氨基肽。当血液进入轴封系统（22,27）时，可防止这些混合物凝结。虽然这种类型的轴封系统（22,27）中的血液以与常规的不同的独特机制凝结，但是即使在这种独特的情况下，蛋白酶和氨肽也不会失去效果。

5. 发明公开

EP0445782A1 Auxiliary artificial heart of the embedded-in-body type 失效
标题翻译： Könstliches，在Körper植入Hilfsherz。
公开(公告)号：EP0445782A1
公开(公告)日：1991-09-11
申请号：EP91103427.0
申请日：1991-03-06
申请人： SUN MEDICAL TECHNOLOGY RESEARCH CORPORATION , Yamazaki, Kenji
发明人： Yamazaki, Kenji
IPC分类号： A61M1/12
CPC分类号： A61M1/101 , A61F2250/0001 , A61M1/1008 , A61M1/1029 , A61M1/1086 , A61M1/1098 , A61M1/12 , A61M1/122 , A61M1/125 , A61M1/127 , A61M2205/15 , A61M2205/33 , A61M2205/3303 , A61M2205/8243 , A61M2230/06 , A61M2230/30 , A61M2230/50 , A61M2230/005
摘要： An auxiliary artificial heart embedded in the human body. The auxiliary artificial heart has an apex cordis area ring (2) and a body (3). The apex cordis area ring (2) is embedded in a cut-out apex cordis area (C) of the human heart. The body (3) includes an elongated pump section (4) and a drive section (5). The pump section (4) is inserted into one of the ventricles (B, J) of the human heart, passing through the apex cordis area ring (2). A front end nozzle (7) whose diameter is smaller than that of the pump section (4) is formed at the front end of the pump section (4), and it is inserted into the aorta or pulmonary artery (G or L), passing through the center of the aorta or pulmonary valve (F or K). The pump section (4) sucks blood in the ventricle through its base portion and feeds it into the aorta or pulmonary artery through the front end nozzle (7).
摘要翻译：辅助人造心脏嵌入人体内。辅助人造心脏具有顶点cordis区域环（2）和主体（3）。顶点cordis区域环（2）嵌入在人的心脏的切口顶点心带区域（C）中。主体（3）包括细长的泵部分（4）和驱动部分（5）。泵部（4）插入人心脏的心室（B，J）中的一个，穿过顶点心区域环（2）。直径小于泵部（4）的前端喷嘴（7）形成在泵部（4）的前端，并且被插入主动脉或肺动脉（G或L）中，通过主动脉或肺动脉瓣的中心（F或K）。泵部分（4）通过其基部吸入心室中的血液，并通过前端喷嘴（7）将其送入主动脉或肺动脉。

6. 发明公开

EP1514571A2 Skin-penetrating medical object holder and blood pump system 有权
标题翻译： Halterfüreine Hautpenetrationsvorrichtung und Blutpumpenanordnung
公开(公告)号：EP1514571A2
公开(公告)日：2005-03-16
申请号：EP04021479.3
申请日：2004-09-09
申请人： SUN MEDICAL TECHNOLOGY RESEARCH CORPORATION
发明人： Yamazaki, Kenji , Oguchi, Kaori , Ushiyama, Hiroyuki
IPC分类号： A61M25/02
CPC分类号： A61M25/02 , A61B50/13 , A61B90/50 , A61M1/1001 , A61M1/101 , A61M1/122 , A61M1/127 , A61M1/28 , A61M1/3661 , A61M39/0247 , A61M2025/0206
摘要： A skin-penetrating medical object holder can effectively suppress detachment of a medical skin-penetrating object and living body tissue due to external forces, and therefore can prevent infections from occurring from the outset. The skin-penetrating medical object holder includes a belt-like holder main body that is wound around a living body and a penetrating object holding part that is disposed on the holder main body and holds a medical skin-penetrating object that passes through the skin of the living body. The penetrating object holding part is constructed so as to guide, in a state where the holder main body has been wound around the living body, the medical skin-penetrating object along a length direction of the holder main body.
摘要翻译：皮肤穿透性医疗用保持具可以有效地抑制由外力引起的医用皮肤穿透物和生物体组织的剥离，因此能够防止一开始就发生感染。皮肤穿透性医疗用保持具具有卷绕在生物体上的带状保持架主体和设置在保持器主体上的穿透物保持部，并且保持穿过皮肤的医用皮肤穿透物体活体。穿透物保持部被构造成在保持器主体围绕生物体缠绕的状态下沿着保持器主体的长度方向引导医用皮肤穿透物。

7. 发明授权

EP0808632B1 Purge solution circulating apparatus for artificial organ 失效
标题翻译：用于人造器官的清洗液循环装置
公开(公告)号：EP0808632B1
公开(公告)日：2003-08-06
申请号：EP97108152.6
申请日：1997-05-20
申请人： SUN MEDICAL TECHNOLOGY RESEARCH CORPORATION
发明人： Yamazaki, Kenji , Mori, Toshio , Hori, Masanori
IPC分类号： A61M1/10
CPC分类号： A61M1/10 , A61M1/101 , A61M1/1015 , A61M1/102 , A61M1/1025 , A61M1/1029 , A61M1/1036 , A61M1/122 , A61M1/125 , A61M1/127 , A61M1/3643 , A61M1/3644 , A61M2205/3606 , A61M2205/3673

8. 发明公开

EP0768091A1 Artificial heart 失效
标题翻译： Kunstherz
公开(公告)号：EP0768091A1
公开(公告)日：1997-04-16
申请号：EP95116289.0
申请日：1995-10-16
申请人： SUN MEDICAL TECHNOLOGY RESEARCH CORPORATION , SEIKO EPSON CORPORATION
发明人： Yamazaki, Kenji , Mori, Toshio , Higuchi, Kouji
IPC分类号： A61M1/10
CPC分类号： F04D29/669 , A61M1/101 , A61M1/1013 , A61M1/102 , A61M1/1031 , A61M1/122 , A61M1/125 , A61M1/127 , A61M2205/8243 , F04D3/005 , F04D29/128
摘要： An artificial heart has a driving section (105) and a pump section (104), and a sealing section (132) forming a seal for a driving shaft extending from the driving section (105) for driving the pump section (104). A sealing liquid chamber (137) filled with a sealing liquid is formed around the driving shaft (130) between the sealing mechanism (132) and the driving section (105). The sealing liquid in the sealing liquid chamber (137) maintains the sealing mechanism (132) in a liquid-tight state and lubricates the sealing mechanism (132), whereby blood is prevented from entering the driving section (105). The sealing mechanism contains a mechanical seal (132), which is provided with a seat ring (133), a follow ring (134) and devices (145, 146) for pressing the follow ring against the seat ring.
摘要翻译：人造心脏具有驱动部分（105）和泵部分（104），以及密封部分（132），形成用于驱动泵部分（104）的驱动部分（105）延伸的驱动轴的密封件。在密封机构（132）和驱动部（105）之间的驱动轴（130）周围形成有填充有密封液体的密封液室（137）。密封液室137中的密封液将密封机构（132）保持在液密状态，润滑密封机构（132），防止血液进入驱动部（105）。密封机构包括机械密封件（132），其设有座圈（133），跟随环（134）和用于将跟随环压靠在座圈上的装置（145,146）。

9. 发明公开

EP1344539A2 Protector and blood pump system 有权
标题翻译： SchutzkappefürPunktionsstellen
公开(公告)号：EP1344539A2
公开(公告)日：2003-09-17
申请号：EP03005686.5
申请日：2003-03-13
申请人： SUN MEDICAL TECHNOLOGY RESEARCH CORPORATION
发明人： Yamazaki, Kenji , Aizawa, Nobuaki
IPC分类号： A61M1/00 , A61M25/02 , A61M1/12 , A61M35/00
CPC分类号： A61M39/0247 , A61M1/1006 , A61M1/1008 , A61M1/101 , A61M1/12 , A61M1/122 , A61M1/127 , A61M1/14 , A61M1/28 , A61M25/02 , A61M2025/0246 , A61M2025/0266 , A61M2025/0273 , A61M2039/0288 , A61M2205/7518
摘要： A protector effectively suppresses infections. The protector (10) protects a tube entry part, where a tube (90) passes through the skin of a living body, from infections, and includes a sticking part (20) that is stuck onto the skin of the living body in a periphery of the tube entry part, and a covering (40) that covers the tube entry part, forms an internal space (P2) that surrounds the tube entry part, and has a passage (P1) through which the tube passes. The covering is provided with an opening (P3) that can be freely opened and closed with a cap (80) or the like.
摘要翻译：保护者有效地抑制感染。保护器（10）保护管（90）穿过生物体的皮肤免受感染的管入口部分，并且包括在外周附着在生物体的皮肤上的粘贴部分（20）和覆盖管入口部分的覆盖物（40）形成围绕管入口部分的内部空间（P2），并且具有管通过的通道（P1）。盖子设置有能够用盖（80）等自由地打开和关闭的开口（P3）。保护者有效地抑制感染。保护器（10）保护管（90）穿过生物体的皮肤免受感染的管入口部分，并且包括在外周附着在生物体的皮肤上的粘贴部分（20）和覆盖管入口部分的覆盖物（40）形成围绕管入口部分的内部空间（P2），并且具有管通过的通道（P1）。盖子设置有能够用盖（80）等自由地打开和关闭的开口（P3）。

10. 发明公开

EP0864333A3 Skin button 失效
标题翻译： Hautknopf
公开(公告)号：EP0864333A3
公开(公告)日：1999-03-03
申请号：EP98104315.1
申请日：1998-03-10
申请人： SUN MEDICAL TECHNOLOGY RESEARCH CORPORATION
发明人： Kojima, Akira , Yamazaki, Kenji , Mori, Toshio , Kobayashi, Sakashi , Tagusari, Osamu
IPC分类号： A61M1/00
CPC分类号： A61M39/0247 , A61M2039/0276 , A61M2039/0279 , A61M2039/0282
摘要： A skin button comprising a cylindrical core component (2) secured in the subcutaneous tissue (7, 8, 9, 10) of the living body as passing through the tissue, the core component has thorough holes which pass through the subcutaneous tissue and let skin penetrating components be inserted which pass into and out of the subcutaneous tissue, the core component (2) has a tubular component (3) made of fiber base material consisting of biocompatible fibers on the rim of the part of the core component which contacts the living tissue. The living tissue grows into the space among fibers of basic fiber materials of the tubular component (3) to securely hold the skin button (1) in the subcutaneous tissue as well as to ensure prevention of bacterial infection.

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