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1. 发明授权

EP2334370B1 TET SYSTEM FOR IMPLANTED MEDICAL DEVICE 有权
公开(公告)号：EP2334370B1
公开(公告)日：2018-12-12
申请号：EP09813371.3
申请日：2009-09-10
申请人： Heartware, Inc.
发明人： YOMTOV, Barry , BATTY, John Robert
IPC分类号： A61N1/00
CPC分类号： A61M1/127 , A61M1/10 , A61M1/101 , A61M1/1086 , A61M1/122 , A61M2205/8243
摘要： A TET system is operable to vary an amount of power transmitted from an external power supply to an implantable power unit in accordance with a monitored condition of the implantable power unit. The amount of power supplied to the implantable power unit for operating a pump, for example, can be varied in accordance with a cardiac cycle, so as to maintain the monitored condition in the power circuit within a desired range throughout the cardiac cycle.

2. 发明公开

EP3196470A4 CENTRIFUGAL PUMP 有权
公开(公告)号：EP3196470A4
公开(公告)日：2018-04-11
申请号：EP15842515
申请日：2015-08-21
申请人： TERUMO CORP
发明人： ITAMOCHI YOSUKE
IPC分类号： F04D13/02 , A61M1/10 , F04D7/04 , F04D29/046 , F04D29/42
CPC分类号： F04D29/4293 , A61M1/10 , A61M1/101 , A61M1/1013 , A61M1/122 , F04D7/04 , F04D13/06 , F04D29/046 , F04D29/0467 , F04D29/22 , F04D29/4273
摘要： [Problem] Provided is a centrifugal pump in which a thrombus can be effectively prevented or restrained from being formed inside a blood inlet port. [Solution] A centrifugal pump 1 includes a housing 2 that is provided with a housing main body 20, a blood inlet port 25, and a blood outlet port 26; a rotary body 3 that is rotatably accommodated inside the housing main body 20; and a support mechanism 4 that supports the rotary body 3. The support mechanism 4 is provided with a rod-like shaft member 5, and a first bearing 6 and a second bearing 7 which respectively and rotatably support end portions of the shaft member 5. In addition, a lower surface 62 of the first bearing 6 is positioned at the same distance as an inner peripheral surface 255 of the blood inlet port 25 from a central axis O of the blood inlet port 25 or is positioned so as to be closer to the central axis O side of the blood inlet port 25 than the inner peripheral surface 255 of the blood inlet port 25.

3. 发明公开

EP3300484A1 INFLOW CANNULA TUNNELING TOOL ALLOWING QUICK EXCHANGE WITH DILATING PLUG 有权
标题翻译： INFLOW CANNULA TUNNELING TOOL允许使用DILATING PLUG快速更换
公开(公告)号：EP3300484A1
公开(公告)日：2018-04-04
申请号：EP16789763.6
申请日：2016-04-27
申请人： CircuLite, Inc.
发明人： FARNAN, Robert, C. , AURILIA, Brad , GOMEZ, Cesar
IPC分类号： A61M39/20 , A61M1/12 , A61M1/10 , A61B17/34
CPC分类号： A61B17/3415 , A61B2017/00243 , A61B2017/320056 , A61M1/10 , A61M1/1008 , A61M1/101 , A61M1/122 , A61M39/20
摘要： A system for facilitating fluid connection between cannulae and a blood pump. The system includes a cannula (52) having a distal end (66) adapted to be in fluid communication with the circulatory system and a proximal end (68) configured to couple to an inlet (82) of the blood pump (54). Further included is a tunneling device (84) configured to be inserted into a body of a patient to direct the proximal end (56) of a cannula (50) adjacent to the inlet (82) and including a connecting structure (90). Further included is a plug (224) which has a first plug part (230) and a second plug part (232). The first plug part (230) includes a connecting structure (92), the connecting structures (90, 92) being selectively engageable. The second plug part (232) is configured to be inserted in the proximal end of the cannula (50). The first and second plug parts (230, 232) are selectively disengageable to allow in situ disconnection between the cannula (50) and tunneling device (84).

4. 发明公开

EP3225262A1 COUNTERPULSATION DEVICE DRIVER APPARATUS, METHOD AND SYSTEM 有权
标题翻译：对流装置驱动装置，方法和系统
公开(公告)号：EP3225262A1
公开(公告)日：2017-10-04
申请号：EP17150905.2
申请日：2012-11-21
申请人： Abiomed, Inc.
发明人： SPENCE, Paul , DOWLING, Rob , KUNG, Bob , HASTIE, Caitlyn , SIESS, Thorsten , GRATZ, Eric , SPANIER, Gerd
IPC分类号： A61M1/10 , A61M1/12
CPC分类号： A61M1/1086 , A61B17/062 , A61B2017/1107 , A61B2017/1135 , A61M1/10 , A61M1/1008 , A61M1/1037 , A61M1/1044 , A61M1/106 , A61M1/1062 , A61M1/107 , A61M1/12 , A61M1/122 , A61M2205/3337 , A61M2205/502 , A61M2230/06
摘要： A method of operating a counterpulsation device (CPD) in a human or animal subject is disclosed, the method including: receiving a heart beat signal indicative of the heart beat of the subject; providing counterpulsation therapy by controlling the pressure supplied to a CPD drive line in pneumatic communication with the CPD to cause the CPD to alternately fill with blood and eject blood with a timing that is determined at least in part based on the heart beat signal; while providing counterpulsation therapy, receiving a CPD drive line pressure signal indicative of the pressure in the CPD drive line; and adjusting the pressure supplied to the drive line based at least in part on the drive line pressure signal.
摘要翻译：公开了一种操作人或动物对象中的反搏装置（CPD）的方法，所述方法包括：接收表示所述对象的心搏的心搏信号; 通过控制提供给在与CPD气动连通的CPD驱动线中的压力提供反搏治疗以使CPD交替充满血液，并使用至少在基于所述心脏的跳动信号部分确定的定时喷射血液; 同时提供反搏治疗，接收指示CPD驱动线中的压力的CPD驱动线压力信号; 以及至少部分地基于驱动管路压力信号来调节供应到驱动管路的压力。

5. 发明公开

EP3195887A1 CENTRIFUGAL PUMP 有权
标题翻译：离心泵
公开(公告)号：EP3195887A1
公开(公告)日：2017-07-26
申请号：EP15841663.6
申请日：2015-08-21
申请人： Terumo Kabushiki Kaisha
发明人： TANAKA, Shotaro , ITAMOCHI, Yosuke
IPC分类号： A61M1/10 , F04D7/04 , F04D13/02 , F04D29/42 , F04D29/60
CPC分类号： A61M1/1013 , A61M1/10 , A61M1/101 , A61M1/122 , A61M2206/20 , F04D7/04 , F04D13/06 , F04D29/043 , F04D29/046 , F04D29/0467 , F04D29/4273 , F04D29/669 , F04D29/688
摘要： [Problem] Provided is a centrifugal pump in which a thrombus can be effectively prevented or restrained from being formed inside a blood inlet port.
[Solution] A centrifugal pump 1 includes a housing 2 that is provided with a housing main body 20, a blood inlet port 25, and a blood outlet port 26; a rotary body 3 that is rotatably accommodated inside the housing main body 20; and a support mechanism 4 that supports the rotary body 3. The support mechanism 4 is provided with a rod-like shaft member 5, and a first bearing 6 and a second bearing 7 which respectively and rotatably support end portions of the shaft member 5. In addition, the first bearing 6 is provided with a protruding portion 62 which is formed so as to protrude in an eccentric manner with respect to a rotation center O when viewed from an upstream side of a blood flow.
摘要翻译：本发明的目的在于提供一种能够有效地防止或抑制在血液导入口内形成血栓的离心泵。离心泵1包括壳体2，壳体2设置有壳体主体20，血液入口25和血液出口26; 可旋转地容纳在壳体主体20内的旋转体3; 以及支撑旋转体3的支撑机构4.支撑机构4具备棒状的轴部件5，以及分别旋转自如地支撑轴部件5的端部的第一轴承6和第二轴承7。此外，第一轴承6设置有突出部62，该突出部62形成为当从血流的上游侧观察时相对于旋转中心O以偏心的方式突出。

6. 发明公开

EP3188771A2 SYSTEM AND METHOD FOR EXTRACORPOREAL TEMPERATURE CONTROL 失效转让
标题翻译：用于体外温度控制的系统和方法
公开(公告)号：EP3188771A2
公开(公告)日：2017-07-12
申请号：EP15832049.9
申请日：2015-08-05
申请人： Medivance Incorporated
发明人： VOORHEES, Marc E. , PARK, Christopher , PRIVITERA, Salvatore
IPC分类号： A61M1/36 , A61B18/02 , A61F7/00
CPC分类号： A61M1/369 , A61F7/0085 , A61F7/12 , A61F2007/0056 , A61F2007/0086 , A61F2007/0096 , A61F2007/126 , A61M1/10 , A61M5/007 , A61M5/14 , A61M19/00 , A61M25/0026 , A61M2205/3355 , A61M2205/3368
摘要： Improved systems and methods for extracorporeal blood temperature control and patient temperature control, e.g., for induced hypothermia and optional normothermia, may include or otherwise employ a heat exchanger for cooling/warming of a fluid, a thermal exchange module having fluidly isolated first and second volumes, and a fluid pump for circulating the fluid through the heat exchanger and the first volume of the thermal exchange module. A blood pump may be provided for the flow of blood through the second volume of the thermal exchange module, and a first controller may be provided for providing output signals for use in operation of the heat exchanger to selectively control thermal exchange between the fluid circulated through the first volume of the thermal exchange module and the blood flowed through the second volume of the thermal exchange module, thereby providing for selective cooling/warming of the blood. A multi lumen catheter may be utilized for the flow of blood from a patient vascular system to the second volume of the thermal exchange module, and for flow of blood from the second volume of the thermal exchange module back to the patient vascular system. The circulated fluid may be optionally circulated through a patient contact pad(s) for contact cooling/warming, wherein patient cooling/warming may be provided in a first mode via blood cooling/warming in the thermal exchange module, and patient cooling/warming may be provided in a second mode via thermal exchange by the contact pad(s).
摘要翻译：用于体外血液温度控制和患者温度控制的改进的系统和方法，例如用于诱导的体温过低和任选的体温过低的系统和方法可以包括或另外采用用于流体冷却/加热的热交换器，具有流体隔离的第一和第二体积以及用于使流体循环通过热交换器和热交换模块的第一容积的流体泵。血液泵可以被提供用于血液流动通过热交换模块的第二容积，并且可以提供第一控制器用于提供用于热交换器的操作的输出信号，以选择性地控制通过循环的流体第一体积的热交换模块和血液流过第二体积的热交换模块，由此提供血液的选择性冷却/加热。多腔导管可用于从患者血管系统到第二体积的热交换模块的血液流动，以及用于从第二体积的热交换模块返回到患者血管系统的血液流动。循环流体可以任选地循环通过患者接触垫以接触冷却/加热，其中患者冷却/加热可以通过热交换模块中的血液冷却/加热以第一模式提供，并且患者冷却/加热可以通过接触垫的热交换以第二模式提供。

7. 发明授权

EP2648803B1 IMPLANTABLE WIRELESS POWER SYSTEM 有权转让
标题翻译：可植入的无线电力系统
公开(公告)号：EP2648803B1
公开(公告)日：2017-04-26
申请号：EP11847692.8
申请日：2011-09-23
申请人： Everheart Systems, Inc.
发明人： ARMSTRONG, Randolph, K. , ABER, Greg, S.
IPC分类号： A61M1/10 , A61M1/12 , H02J5/00 , H02J7/02
CPC分类号： A61M1/1086 , A61M1/10 , A61M1/101 , A61M1/12 , A61M1/122 , A61M1/127 , A61M2205/8243 , H01F38/14 , H02J5/005 , H02J7/025 , H02J50/12
摘要： The present invention refers to an apparatus for use in wireless energy transfer to power an electronic device. The apparatus comprises a transmitting assembly configured to transmit electromagnetic energy, whereby the transmitting assembly comprises a transmitting resonant coil providing a first conductor and a first electrical insulating medium between coil turns of said first conductor. The apparatus further comprises a receiving assembly magnetic resonance coupled to the transmitting assembly, whereby the receiving assembly comprises a receiving resonant coil providing a second conductor and a second electrical insulating medium between coil turns of said second conductor. A first capacitor is electrically connected to the first conductor and a second capacitor is electrically connected to the second conductor. The first and/or second insulating medium comprises one or more dielectric materials that is solid with a polygonal cross section. Further the first and/or second insulating medium provides a dielectric dissipation factor of 0.01 or less. The first and/or second conductor has a thickness T of less than 0.0508 cm [0.020 inches] and a width W of 1.27 cm [0.5 inches] or less, wherein the transmitting and/or receiving resonant coil has a diameter of 7.62 cm [3 inches] or less.
摘要翻译：无线电力系统能够通过皮肤传输电力，而不需要经皮电线，距离范围从几英寸到几英尺，包括外部发射线圈组件和接收线圈组件。发送线圈组件包括彼此电感耦合的激励线圈和发送谐振线圈。接收线圈组件包括也相互感应耦合的接收谐振线圈和功率拾取线圈。诸如射频（RF）之类的高频AC功率输入以感应方式提供给励磁线圈，导致发射谐振线圈谐振，导致局部时变磁场。发射和接收谐振线圈被构造为具有紧密匹配或相同的谐振频率，使得由发射谐振线圈产生的磁场也能够使接收谐振线圈也强烈地谐振，即使当两个谐振线圈大大超过任一线圈的最大尺寸。接收谐振线圈然后产生其自身的局部时变磁场，其在感应拾取线圈中感应产生电压以向有源可植入医疗装置或可植入可再充电电池提供电力。

8. 发明授权

EP3060270B1 VERFAHREN ZUM BETRIEB EINER PUMPENEINRICHTUNG SOWIE PUMPENEINRICHTUNG 有权
公开(公告)号：EP3060270B1
公开(公告)日：2017-04-19
申请号：EP14786920.0
申请日：2014-10-21
申请人： Berlin Heart GmbH
发明人： WIESENER, Constantin , KARCH, Dominik
IPC分类号： A61M1/10
CPC分类号： A61M1/1086 , A61M1/0023 , A61M1/10 , A61M1/101 , A61M1/1015 , A61M1/1017 , A61M1/1029 , A61M1/1031 , A61M1/1087 , A61M1/1096 , A61M1/1098 , A61M1/122 , A61M2230/005 , A61M2230/63

9. 发明公开

EP3096748A1 MATERIALS, METHODS AND DEVICES FOR ALTERING CELL REACTIVITY 审中-公开
标题翻译： MATERIALIEN，VERFAHREN UND VORRICHTUNGEN ZURVERÄNDERUNGDERZELLREAKTIVITÄT
公开(公告)号：EP3096748A1
公开(公告)日：2016-11-30
申请号：EP15704426.4
申请日：2015-01-26
申请人： The Arizona Board of Regents on behalf of the University of Arizona
发明人： SLEPIAN, Marvin J.
IPC分类号： A61K31/10 , C12N5/078 , A61K31/165 , A61K31/202
CPC分类号： A61K31/10 , A61K31/165 , A61K31/202 , A61K31/337 , A61K31/407 , A61K31/575 , A61K31/685 , A61K35/19 , A61M1/10 , C12N5/0006 , C12N5/0644 , C12N2500/36 , C12N2500/62
摘要： Methods, compositions, and devices to limit, modulate, insulate, and/or otherwise alter the effects of exogenous physical stimuli on cells are described herein. The cells may be removed from the body, preferably isolated, and treated ex vivo with the composition to limit the effects of physical stimuli on the cells and then returned to the patient. Alternatively, the cells may be treated in vivo. The compositions can be administered a variety of manners, such as systemically, locally or regionally.
摘要翻译：本文描述了限制，调节，绝缘和/或以其它方式改变外源物理刺激对细胞的作用的方法，组合物和装置。细胞可以从体内移除，优选分离，并且用组合物离体处理以限制物理刺激对细胞的影响，然后返回到患者体内。或者，可以在体内处理细胞。组合物可以以各种方式施用，例如全身，局部或区域。

10. 发明公开

EP3086823A1 BLOOD OXYGENATOR 有权
标题翻译： BLUTOXYGENATOR
公开(公告)号：EP3086823A1
公开(公告)日：2016-11-02
申请号：EP14874043.4
申请日：2014-12-23
申请人： University of Maryland, Baltimore
发明人： WU, Zhongjun , GRIFFITH, Bartley P.
IPC分类号： A61M1/14 , A61M1/18 , A61M1/34
CPC分类号： A61M1/1698 , A61M1/10 , A61M1/1006 , A61M1/1086 , A61M2202/0208 , A61M2205/3334 , A61M2205/3368 , A61M2205/366 , A61M2206/10 , A61M2206/16 , A61M2209/088
摘要： A blood oxygenator is disclosed comprising a housing, a blood inlet, a blood outlet, a spiral volute, a gas inlet, an oxygenator fiber bundle, and a gas outlet. The housing encloses the fiber bundle and provides the structure for the blood flow path and connectors. The fiber bundle comprises gas-exchange membranes which transfer oxygen to the blood and remove carbon dioxide when the blood flows across the membranes. The spiral volute guides the blood to flow through the fiber bundle. A gas flow chamber receives sweep gas containing oxygen and distributes the sweep gas into the fiber membranes, which gas is then exchanged with the blood being oxygenated.
摘要翻译：公开了一种血液充氧器，其包括壳体，血液入口，血液出口，螺旋形蜗壳，气体入口，氧合器纤维束和气体出口。外壳包围纤维束，并提供血流路径和连接器的结构。纤维束包括气体交换膜，当血液流过膜时，氧气转移到血液中并去除二氧化碳。螺旋蜗壳引导血液流过纤维束。气流室接收含有氧气的吹扫气体并将吹扫气体分配到纤维膜中，然后将这些气体与被氧化的血液交换。

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