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1. 发明公开

EP2127540A1 SKIN-BEAUTIFYING AGENT 审中-公开
标题翻译：皮肤美白剂
公开(公告)号：EP2127540A1
公开(公告)日：2009-12-02
申请号：EP08704064.8
申请日：2008-01-29
申请人： Snow Brand Milk Products Co., Ltd.
发明人： KATO, Ken , HARUTA, Yuko , WATANABE, Tatsuya , UENO, Hiroshi , UEDA, Noriko , YOSHIOKA, Toshimitsu
IPC分类号： A23L1/30 , A23K1/16 , A61K35/20 , A61K38/00 , A61P17/00
CPC分类号： A61K31/661 , A23K20/158 , A23K50/40 , A23L33/10 , A23L33/12 , A23V2002/00 , A23V2200/318 , A23V2250/18
摘要： The present invention aims to provide a skin-beautifying agent, food, beverage, or feed for skin-beautification which has cosmetic effects such as moisturizing and beautifying the skin as well as preventing skin roughness and wrinkles by oral intake. The present invention further aims to provide a skin-beautifying agent containing a milk-derived phospholipid as an effective ingredient, and to provide food, beverage, or feed for skin-beautification containing the skin-beautifying agent. The milk-derived phospholipid is preferably a composition prepared from milk or milk material containing 40 to 70% by weight of lipid in a total solid content and containing 30% or more by weight of milk-derived phospholipid.
摘要翻译：本发明的目的在于提供一种具有保湿，美化皮肤等美容效果并且通过口服摄取来防止皮肤粗糙和皱纹的皮肤美化剂，食品，饮料或美容用饲料。本发明的目的还在于提供一种含有乳来源的磷脂作为有效成分的美肤剂，并且提供含有该美肤剂的用于美肤的食品，饮料或饲料。乳来源的磷脂优选为由乳或乳原料制备的组合物，其含有总固体含量为40至70重量％的脂质，并且含有30重量％或更多的源自乳源的磷脂。

2. 发明公开

EP1938824A1 MEDICINE, FOOD AND DRINK OR FEED CONTAINING SPHINGOMYELIN 有权
标题翻译： SPHINGOMYELIN ENTHALTENDE MEDIZIN，NAHRUNGSMITTEL UNDGETRÄNK
公开(公告)号：EP1938824A1
公开(公告)日：2008-07-02
申请号：EP06810466.0
申请日：2006-09-22
申请人： SNOW BRAND MILK PRODUCTS CO., LTD.
发明人： KATO, Ken , MIURA, Susumu , TANAKA, Leo , UENO, Hiroshi , UEDA, Noriko , HARUTA, Yuko , YOSHIOKA, Toshimitsu
IPC分类号： A61K31/688 , A23K1/16 , A23L1/30 , A61K8/68 , A61K35/20 , A61P1/00 , A61P17/00 , A61P17/14 , A61P21/00 , A61P25/28 , A61P29/00 , A61P31/00 , A61P37/08 , A61P39/06 , A61Q7/00 , A61Q19/02
CPC分类号： A61K31/688 , A23K20/158 , A23K50/40 , A23K50/48 , A23L2/52 , A23L33/10 , A23L33/12 , A23V2002/00 , A61K8/68 , A61Q7/00 , A61Q19/02 , C07F9/10 , A23V2250/21 , A23V2200/304 , A23V2200/32
摘要： It is intended to find novel pharmaceutical use of sphingomyelin and to provide preventive or therapeutic agents for various diseases as well as a food and drink product and feed comprising any of these agents. The present invention provides a pharmaceutical agent which contains sphingomyelin as an active ingredient and is any of the following agents: 1) a sialomucin secretion promoter, 2) an agent for preventing drunken sickness (hangover), 3) an antiallergic agent, 4) an antioxidant, 5) an agent for defending against infection, 6) a hair growth agent, 7) a therapeutic agent for demyelinating disease, 8) an anti-pigmentation agent, 9) an anti-inflammatory agent, and 10) an agent for improving learning ability. The present invention also provides a food and drink product or feed, characterized by comprising the agent. It is preferred that the sphingomyelin should be derived from milk.
摘要翻译：旨在找到鞘磷脂的新药用途，并提供各种疾病的预防或治疗剂，以及包含任何这些药剂的食品和饮料产品和饲料。本发明提供含有鞘磷脂作为活性成分的药剂，其为以下药剂：1）唾液酸粘蛋白分泌促进剂，2）防止酒醉（宿醉）的药剂，3）抗过敏剂，4）抗氧化剂，5）防止感染的药剂，6）毛发生长剂，7）脱髓鞘疾病的治疗剂，8）抗色素沉着剂，9）抗炎剂，和10）改善剂学习能力本发明还提供一种食品和饮料产品或饲料，其特征在于包含该试剂。鞘磷脂优选来源于牛奶。

3. 发明公开

EP2221057A1 SENSE-IMPROVING AGENT 审中-公开
标题翻译：生产资料改善感官
公开(公告)号：EP2221057A1
公开(公告)日：2010-08-25
申请号：EP08851416.1
申请日：2008-11-19
申请人： Snow Brand Milk Products Co., Ltd.
发明人： WATANABE, Tatsuya , HARUTA, Yuko , KATO, Ken , YOSHIOKA, Toshimitsu
IPC分类号： A61K31/688 , A23L1/30 , A61K8/55 , A61P25/02 , A61Q19/00
CPC分类号： A61Q19/00 , A23K20/158 , A23K20/26 , A23K50/40 , A23L2/52 , A23L33/115 , A61K8/0212 , A61K8/553 , A61K8/68 , A61K31/688
摘要： Disclosed are: sense-improving agent which comprises, as an active ingredient, a phospholipid or a sphingosine-containing phospholipid and/or a derivative thereof, particularly a sphingomyelin, and which has an effect of improving the dulling of senses at a periphery when ingested orally or directly applied to the skin; and a sense-improving food, beverage, feed or cosmetic comprising the sense-improving agent. The phospholipid to be used may be a chemically synthesized phospholipid or a naturally occurring phospholipid, preferably a phospholipid derived from an edible material such as soybean and egg yolk, particularly preferably a phospholipid derived from milk.

4. 发明授权

EP1938824B1 MEDICINE, FOOD AND DRINK OR FEED CONTAINING SPHINGOMYELIN 有权
标题翻译：鞘磷脂含药物，食品和饮料
公开(公告)号：EP1938824B1
公开(公告)日：2011-11-30
申请号：EP06810466.0
申请日：2006-09-22
申请人： SNOW BRAND MILK PRODUCTS CO., LTD.
发明人： KATO, Ken , MIURA, Susumu , TANAKA, Leo , UENO, Hiroshi , UEDA, Noriko , HARUTA, Yuko , YOSHIOKA, Toshimitsu
IPC分类号： A61K31/688 , A23K1/16 , A23L1/30 , A61K8/68 , A61K35/20 , A61P1/00 , A61P17/00 , A61P17/14 , A61P21/00 , A61P25/28 , A61P29/00 , A61P31/00 , A61P37/08 , A61P39/06 , A61Q7/00 , A61Q19/02
CPC分类号： A61K31/688 , A23K20/158 , A23K50/40 , A23K50/48 , A23L2/52 , A23L33/10 , A23L33/12 , A23V2002/00 , A61K8/68 , A61Q7/00 , A61Q19/02 , C07F9/10 , A23V2250/21 , A23V2200/304 , A23V2200/32
摘要： It is intended to find a novel medicinal application of sphingomyelin and to provide a preventive agent or a therapeutic agent for various diseases and a food and drink and feed containing the agent. A medicine which contains sphingomyelin as an active ingredient and is any of the following agents: 1) a sialomucin secretion promoter, 2) an agent for preventing getting sick from drinking, 3) an antiallergic agent, 4) an antioxidant, 5) an agent for preventing infection, 6) a hair growth agent, 7) a therapeutic agent for a demyelinating disease, 8) an anti-pigmentation agent, 9) an antiinflammatory agent or 10) an agent for improving learning ability. The food and drink or the feed is characterized by comprising the agent. The sphingomyelin is preferably derived from milk.

5. 发明公开

EP2156820A1 SKIN WHITENING AGENT 有权
标题翻译： HAUTBLEICHUNGSMITTEL
公开(公告)号：EP2156820A1
公开(公告)日：2010-02-24
申请号：EP08764523.0
申请日：2008-05-22
申请人： Snow Brand Milk Products Co., Ltd.
发明人： WATANABE, Tatsuya , KATO, Ken , UENO, Hiroshi , HARUTA, Yuko , UEDA, Noriko , YOSHIOKA, Toshimitsu
IPC分类号： A61K8/64 , A23K1/16 , A23K1/175 , A23L1/30 , A23L1/305 , A23L2/52 , A61K8/19 , A61K8/26 , A61K8/27 , A61K9/08 , A61K33/06 , A61K33/10 , A61K33/24 , A61K33/26 , A61K33/30 , A61K33/32 , A61K33/34 , A61K38/16 , A61P17/00 , A61Q19/02
CPC分类号： A61K33/34 , A23K20/105 , A23K20/147 , A23K20/20 , A23K50/40 , A23L33/10 , A23L33/19 , A61K8/19 , A61K8/64 , A61K9/0014 , A61K31/19 , A61K33/06 , A61K33/10 , A61K33/24 , A61K33/26 , A61K33/30 , A61K33/32 , A61K38/16 , A61K38/40 , A61K45/06 , A61Q19/02 , A61K2300/00
摘要： Disclosed are: a skin whitening agent comprising, as an active ingredient, a complex of carbonic acid and/or bicarbonic acid, a metal and an LF, a decomposition product of the complex, or a complex of carbonic acid and/or bicarbonic acid, a metal and a decomposition product of an LF; and a food, beverage, feed or cosmetic comprising the skin whitening agent. The skin whitening agent can be ingested safely on a daily basis, and exhibits an excellent skin whitening effect.
摘要翻译：公开了一种皮肤增白剂，其包含作为活性成分的碳酸和/或碳酸氢盐，金属和LF的络合物，络合物的分解产物或碳酸和/或碳酸氢盐的络合物， LF的金属和分解产物; 和包含皮肤增白剂的食品，饮料，饲料或化妆品。皮肤美白剂可以每天安全摄取，并具有优异的皮肤美白效果。

6. 发明公开

EP2138159A1 WHITENING AGENT 审中-公开
标题翻译：美白剂
公开(公告)号：EP2138159A1
公开(公告)日：2009-12-30
申请号：EP08721729.5
申请日：2008-03-10
申请人： Snow Brand Milk Products Co., Ltd.
发明人： WATANABE, Tatsuya , KATO, Ken , UENO, Hiroshi , HARUTA, Yuko , UEDA, Noriko , YOSHIOKA, Toshimitsu
IPC分类号： A61K8/64 , A23C21/00 , A23L1/305 , A23L2/52 , A61K35/20 , A61K38/00 , A61P17/00 , A61Q19/02
CPC分类号： A61K35/20 , A23C9/1526 , A23K20/147 , A23K50/40 , A23L2/52 , A23L33/18 , A23L33/19 , A61K8/64 , A61K38/00 , A61K38/018 , A61K2800/92 , A61Q19/02
摘要： A skin-whitening agent offering an excellent whitening effect and being effective in preventing and treating age spots, freckles, etc., where such skin-whitening agent contains as its effective ingredient a whey protein hydrolyzate characterized by a molecular weight distribution of 10 kDa or less, main peak of 200 Da to 3 kDa, APL (average peptide-chain length) of 2 to 8, free amino acid content of 20% or less, and antigenicity of one-ten thousandth of β-lactoglobulin or less, as well as a cosmetic, drink or food, feed, pharmaceutical preparation or other skin-whitening product containing such skin-whitening agent.
摘要翻译：本发明提供美白效果优异，能够有效预防和治疗老年斑，雀斑等的美白剂，其中，该美白剂含有以分子量分布10kDa为特征的乳清蛋白水解物作为有效成分，或 200Da〜3kDa的主峰，2〜8的APL（平均肽链长度），20％以下的游离氨基酸含量，以及β-乳球蛋白的千分之一以下的抗原性作为含有这种美白剂的化妆品，饮料或食品，饲料，药物制剂或其他美白产品。

7. 发明公开

EP2011500A1 FAT ACCUMULATION INHIBITOR 无效
标题翻译：化学发光二极管代谢综合征
公开(公告)号：EP2011500A1
公开(公告)日：2009-01-07
申请号：EP07741227.8
申请日：2007-04-06
申请人： Snow Brand Milk Products Co., Ltd.
发明人： TANAKA, Reo , ISOGAI, Tomoyuki , HARUTA, Yuko , MIURA, Susumu , KATO, Ken , YOSHIOKA, Toshimitsu , KAWAKAMI, Hiroshi , HIGURASHI, Satoshi , MATSUYAMA, Hiroaki
IPC分类号： A61K31/661 , A23L1/30 , A23L2/00 , A61K35/20 , A61P3/04
CPC分类号： A61K35/20 , A23L2/52 , A23L33/19 , A23V2002/00 , A61K31/661 , A23V2200/332 , A23V2250/1844
摘要： To provede a fat accumulation inhibitor and a food or drink for inhibiting fat accumulation, a visceral fat accumulation inhibitor and a food or drink for inhibiting visceral fat accumulation, or an agent for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood and a food or drink for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood.
A fat accumulation inhibitor for a fat cell, which comrises a milk-derived phospholipid as an active ingredient, and a food or drink for inhibiting fat accumulation in a fat cell, which comprises a milk-derived phospholipid. A visceral fat accumulation inhibitor comprising a sphingosine-containing phospholipid or a derivative thereof as an active ingredient, and a food or drink for inhibiting visceral fat accumulation. An agent for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood , which comprises a sphingosine-containing phospholipid or a derivative thereof as an active ingredient, and a food or drink for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood.
摘要翻译：证明脂肪蓄积抑制剂和用于抑制脂肪蓄积的食物或饮料，内脏脂肪蓄积抑制剂和用于抑制内脏脂肪蓄积的食品或饮料，或用于加速和/或抑制血液中脂联素浓度降低的试剂，以及用于加速和/或抑制血液中脂联素浓度降低的食物或饮料。一种脂肪蓄积抑制剂，其含有来自乳的磷脂作为活性成分的脂肪细胞，以及用于抑制脂肪细胞中的脂肪蓄积的食品或饮料，其包含乳源性磷脂。一种含有含鞘氨醇的磷脂或其衍生物作为活性成分的内脏脂肪蓄积抑制剂和抑制内脏脂肪蓄积的食品或饮料。用于促进增加和/或抑制血液中脂联素浓度降低的试剂，其包含含鞘氨醇的磷脂或其衍生物作为活性成分，以及用于加速和/或抑制脂联素浓度降低的食品或饮料在血液中

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