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1. 发明公开

EP2835092A1 FLUORESCENT OBSERVATION DEVICE AND METHOD FOR OPERATING FLUORESCENT OBSERVATION DEVICE 审中-公开
标题翻译：荧光观测装置及其操作方法荧光观察装置
公开(公告)号：EP2835092A1
公开(公告)日：2015-02-11
申请号：EP13772945.5
申请日：2013-03-28
申请人： Olympus Corporation , Olympus Medical Systems Corp.
发明人： KUBO, Kei , ISHIHARA, Yasushige , SHIDA, Hiromi , TAKEKOSHI, Satoshi
IPC分类号： A61B1/00 , A61B1/04
CPC分类号： G01N21/6456 , A61B1/00009 , A61B1/0005 , A61B1/00055 , A61B1/043 , A61B1/045 , F04C2270/041 , G01N2201/124 , G06K9/4604 , G06T7/0012 , G06T2207/30004
摘要： The invention provides a fluoroscopy apparatus including an image-capturing device (19) that acquires a fluorescence image of a subject (A); a sensitivity adjusting portion (23) that sets a sensitivity of the image-capturing device (19) to fluorescence on the basis of a gradation value of the fluorescence image; a notifying portion (25) that extracts a lesion part from the fluorescence image acquired by the image-capturing device (19) with the sensitivity set by the sensitivity adjusting portion (23) and presents it to an operator; and a display switching portion (24) that displays the fluorescence image on a display unit (7) when the sensitivity in the image-capturing device (19) is equal to or less than a predetermined threshold and that presents information showing the existence of the lesion part on the notifying portion (25) when the sensitivity is greater than the predetermined threshold.
摘要翻译：本发明提供了包含（19）做了一个图像拍摄装置取得被检体（A）的荧光图像的荧光观察装置; 灵敏度调整部（23）做了将图像拍摄装置（19）的荧光的荧光图像的灰度值的基础上的灵敏度; 通知部（25）做了提取病变部从与由灵敏度调节部（23）中设定的灵敏度的摄像装置（19）取得的荧光图像，并且将其呈现给操作者处; 以及显示切换部（24）做了显示器的显示单元（7）当在图像捕获装置（19）的灵敏度是大于预定阈值等于或小于上的荧光图像和没有给出了显示的该存在信息病变的部分通知部（25）当灵敏度大于所述预定阈值。

2. 发明公开

EP2596739A1 MEDICAL APPARATUS 无效转让
标题翻译：医疗设备
公开(公告)号：EP2596739A1
公开(公告)日：2013-05-29
申请号：EP11849714.8
申请日：2011-11-08
申请人： OLYMPUS MEDICAL SYSTEMS CORP.
发明人： KUBO, Kei , DOGUCHI, Nobuyuki
IPC分类号： A61B1/00 , A61B1/06
CPC分类号： A61B1/043 , A61B1/00006 , A61B1/041 , A61B1/0661 , G06F19/00
摘要： A medical apparatus of the present invention comprises: a storing section in which information concerning a drug kinetics in a living body is stored in advance for each of plural kinds of fluorescent drugs; an arithmetic processing section that acquires diagnosis start time corresponding to a desired fluorescent drug based on information stored in the storing section, information concerning a target region of an object to be examined to which the desired fluorescent drug is administered, information concerning a method of administering the desired fluorescent drug to the target region, and information concerning administration start time of the desired fluorescent drug; and a light source control section that performs control to stop radiation of excitation light for exciting the desired fluorescent drug in at least a time period from the administration start time until the diagnosis start time is reached and performs control to radiate the excitation light based on the diagnosis start time.
摘要翻译：本发明的医疗设备包括：存储部分，其中预先存储关于多种荧光药物中的每一种的关于活体中的药物动力学的信息; 算术处理部分，其基于存储在存储部分中的信息获取与期望的荧光药物相对应的诊断开始时间;关于被施用了期望的荧光药物的待检查对象的目标区域的信息;关于施用方法的信息所需的荧光药物到目标区域，以及关于所需荧光药物的给药开始时间的信息; 以及光源控制部，其在从管理开始时刻起至到达诊断开始时刻为止的期间内，至少停止激励期望的荧光药剂的激发光的照射，并进行控制以基于诊断开始时间。

3. 发明公开

EP2599428A1 MEDICAL DEVICE 失效转让
标题翻译：医疗装置
公开(公告)号：EP2599428A1
公开(公告)日：2013-06-05
申请号：EP11861073.2
申请日：2011-12-15
申请人： OLYMPUS MEDICAL SYSTEMS CORP.
发明人： KUBO, Kei , KUGIMIYA, Hideyuki
IPC分类号： A61B1/00 , A61B1/06 , G01N21/27 , G01N21/64
CPC分类号： A61B1/043 , A61B1/00006 , A61B1/041 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61M5/168 , G06F19/00
摘要： A medical apparatus includes a storing section in which information concerning a drug movement in a living body is stored in advance for each of types of a plurality of fluorescent drugs, an arithmetic processing section that acquires, based on the information stored in the storing section, a target region to which a first fluorescent drug is administered, a method of administering the first fluorescent drug to the target region, and administration time, diagnosis start time and diagnosis end time corresponding to the first fluorescent drug and sets, based on the diagnosis end time corresponding to the first fluorescent drug, administration start time of a second fluorescent drug, and a control section that performs control for starting administration of the second fluorescent drug when a current time reaches the administration start time of the second fluorescent drug and, when the current time exceeds the diagnosis end time corresponding to the first fluorescent drug, performs control for lowering an irradiating light amount of excitation light for exciting the first fluorescent drug.
摘要翻译：医疗设备包括：存储部分，其中针对多种荧光药物的每种类型预先存储关于活体中的药物移动的信息;运算处理部分，其基于存储在存储部分中的信息，向第一荧光药剂施用的目标区域，向目标区域施用第一荧光药物的方法以及与第一荧光药剂对应的施用时间，诊断开始时间和诊断结束时间，并且基于诊断结束与第一荧光药剂相对应的时间，第二荧光药剂的给药开始时间，以及当当前时间达到第二荧光药剂的给药开始时间时执行用于开始第二荧光药剂的给药的控制的控制部件，并且当当前时间超过第一荧光药对应的诊断结束时间，进行对照 l用于降低用于激发第一荧光药物的激发光的照射光量。

4. 发明授权

EP2322075B1 FLUORESCENCE OBSERVATION DEVICE 有权转让
标题翻译： FLUORESZENZBEOBACHTUNGSGERÄT
公开(公告)号：EP2322075B1
公开(公告)日：2012-12-05
申请号：EP09843058.0
申请日：2009-10-09
申请人： Olympus Medical Systems Corp.
发明人： KUBO, Kei , TAKEI, Shunji
IPC分类号： A61B1/05 , A61B1/06 , A61B5/00 , G01N21/64 , A61B1/045
CPC分类号： A61B1/05 , A61B1/00009 , A61B1/00186 , A61B1/043 , A61B1/045 , A61B1/0638 , A61B1/0646 , A61B5/0071 , A61B5/0084 , G01N21/6428 , G01N21/6456 , G01N2021/6419 , G01N2021/6421 , G01N2021/6441 , G01N2021/6493
摘要： A fluorescence observation apparatus according to the present invention includes a light source section that emits excitation light for exciting a first fluorescent substance and a second fluorescent substance, a fluorescence detection section that detects first fluorescent light emitted when the first fluorescent substance is excited and second fluorescent light emitted when the second fluorescent substance is excited, a correction value calculation section that calculates a correction value for canceling a color mixture between the first fluorescent light and the second fluorescent light based on feature values corresponding to characteristics of the first fluorescent substance and the second fluorescent substance, a detected image generation section that generates a first detected image corresponding to a detection result of the first fluorescent light and a second detected image corresponding to a detection result of the second fluorescent light, and an image correction section that corrects a luminance value of the first detected image to a luminance value corresponding to intensity of the first fluorescent light and corrects a luminance value of the second detected image to a luminance value corresponding to intensity of the second fluorescent light.

5. 发明公开

EP2599429A1 MEDICAL DEVICE 有权
标题翻译：医疗装置
公开(公告)号：EP2599429A1
公开(公告)日：2013-06-05
申请号：EP11861140.9
申请日：2011-12-15
申请人： OLYMPUS MEDICAL SYSTEMS CORP.
发明人： KUBO, Kei , KUGIMIYA, Hideyuki
IPC分类号： A61B1/00 , A61B1/06 , G01N21/27 , G01N21/64
CPC分类号： A61B1/041 , A61B1/00147 , A61B1/043 , A61B1/045 , A61B5/0059 , A61B5/0071 , A61B5/0084 , A61B5/0086 , A61B5/073 , G06F19/00
摘要： A medical apparatus includes a storing section in which information concerning a drug movement in a living body is stored in advance for each of types of a plurality of fluorescent drugs, an arithmetic processing section that acquires, based on the information stored in the storing section, information concerning a target region of a subject to which a desired fluorescent drug is administered, information concerning a method of administering the desired fluorescent drug to the target region, and information concerning start time of administration of the desired fluorescent drug, diagnosis start time corresponding to the desired fluorescent drug, an image pickup section that picks up an image of an object in the subject, a position information acquiring section that acquires position information of the image pickup section, and a light source control section that performs control, from the administration start time to the diagnosis start time, so as to stop irradiation of excitation light for exciting the desired fluorescent drug and to irradiate the excitation light based on the diagnosis start time and the position information.
摘要翻译：医疗设备包括：存储部分，其中针对多种荧光药物的每种类型预先存储关于活体中的药物移动的信息;运算处理部分，其基于存储在存储部分中的信息，关于施用了期望的荧光药物的对象的目标区域的信息，关于将期望的荧光药物施用至目标区域的方法的信息以及关于期望的荧光药物的施用开始时间的信息，期望的荧光药物，摄取被摄体中的被摄体的图像的摄像部，从摄影开始起取得摄影部的位置信息的位置信息取得部以及进行控制的光源控制部到诊断开始时间的时间，以停止激发光的照射 ht以激发期望的荧光药物并基于诊断开始时间和位置信息照射激发光。

6. 发明授权

EP2599429B1 MEDICAL APPARATUS 有权
公开(公告)号：EP2599429B1
公开(公告)日：2015-11-18
申请号：EP11861140.9
申请日：2011-12-15
申请人： Olympus Corporation
发明人： KUBO, Kei , KUGIMIYA, Hideyuki
IPC分类号： A61B1/00 , A61B1/06 , G01N21/27 , G01N21/64 , A61B5/07 , A61B1/04 , A61B1/045 , A61B5/00
CPC分类号： A61B1/041 , A61B1/00147 , A61B1/043 , A61B1/045 , A61B5/0059 , A61B5/0071 , A61B5/0084 , A61B5/0086 , A61B5/073 , G06F19/00
摘要： A medical apparatus includes a storing section in which information concerning a drug movement in a living body is stored in advance for each of types of a plurality of fluorescent drugs, an arithmetic processing section that acquires, based on the information stored in the storing section, information concerning a target region of a subject to which a desired fluorescent drug is administered, information concerning a method of administering the desired fluorescent drug to the target region, and information concerning start time of administration of the desired fluorescent drug, diagnosis start time corresponding to the desired fluorescent drug, an image pickup section that picks up an image of an object in the subject, a position information acquiring section that acquires position information of the image pickup section, and a light source control section that performs control, from the administration start time to the diagnosis start time, so as to stop irradiation of excitation light for exciting the desired fluorescent drug and to irradiate the excitation light based on the diagnosis start time and the position information.

7. 发明授权

EP2599428B1 MEDICAL APPARATUS 失效转让
标题翻译：医疗设备
公开(公告)号：EP2599428B1
公开(公告)日：2017-09-06
申请号：EP11861073.2
申请日：2011-12-15
申请人： Olympus Corporation
发明人： KUBO, Kei , KUGIMIYA, Hideyuki
IPC分类号： A61B1/00 , A61B1/06 , G01N21/27 , G01N21/64 , A61B1/04 , A61M5/168
CPC分类号： A61B1/043 , A61B1/00006 , A61B1/041 , A61B1/0638 , A61B1/0646 , A61B1/0669 , A61M5/168 , G06F19/00
摘要： A medical apparatus includes a storing section in which information concerning a drug movement in a living body is stored in advance for each of types of a plurality of fluorescent drugs, an arithmetic processing section that acquires, based on the information stored in the storing section, a target region to which a first fluorescent drug is administered, a method of administering the first fluorescent drug to the target region, and administration time, diagnosis start time and diagnosis end time corresponding to the first fluorescent drug and sets, based on the diagnosis end time corresponding to the first fluorescent drug, administration start time of a second fluorescent drug, and a control section that performs control for starting administration of the second fluorescent drug when a current time reaches the administration start time of the second fluorescent drug and, when the current time exceeds the diagnosis end time corresponding to the first fluorescent drug, performs control for lowering an irradiating light amount of excitation light for exciting the first fluorescent drug.
摘要翻译：医疗设备包括：存储部分，其中针对多种荧光药物的每种类型预先存储关于活体中的药物移动的信息;运算处理部分，其基于存储在存储部分中的信息，向第一荧光药剂施用的目标区域，向目标区域施用第一荧光药物的方法以及与第一荧光药剂对应的施用时间，诊断开始时间和诊断结束时间，并且基于诊断结束与第一荧光药剂相对应的时间，第二荧光药剂的给药开始时间，以及当当前时间达到第二荧光药剂的给药开始时间时执行用于开始第二荧光药剂的给药的控制的控制部件，并且当当前时间超过第一荧光药对应的诊断结束时间，进行对照 l用于降低用于激发第一荧光药物的激发光的照射光量。

8. 发明授权

EP2384689B1 FLUORESCENCE OBSERVATION DEVICE 有权转让
标题翻译：荧光观察装置
公开(公告)号：EP2384689B1
公开(公告)日：2016-12-07
申请号：EP10824738.8
申请日：2010-09-14
申请人： Olympus Corporation
发明人： KUBO, Kei , DOGUCHI, Nobuyuki , IMAIZUMI, Katsuichi , TAKEI, Shunji
IPC分类号： A61B1/04 , A61B1/00
CPC分类号： A61B1/045 , A61B1/00009 , A61B1/00186 , A61B1/043 , A61B1/0638 , A61B1/0646 , A61B1/0653 , A61B1/0669 , A61B5/0071 , A61B5/0084

9. 发明公开

EP3037030A1 FLUORESCENCE OBSERVATION APPARATUS 审中-公开
标题翻译： FLUORESZENZBEOBACHTUNGSVORRICHTUNG
公开(公告)号：EP3037030A1
公开(公告)日：2016-06-29
申请号：EP14838502.4
申请日：2014-07-14
申请人： Olympus Corporation
发明人： KUBO, Kei , ISHIHARA, Yasushige
IPC分类号： A61B1/00 , A61B1/04
CPC分类号： A61B5/0071 , A61B1/00009 , A61B1/0005 , A61B1/043 , A61B1/045 , A61B1/0638 , A61B1/0646 , G06T5/008 , G06T5/50 , G06T19/006 , G06T19/20 , G06T2207/10064 , G06T2207/10068 , G06T2207/20212
摘要： Provided is a fluorescence observation apparatus (100) including a light source (3) that radiates illumination light and excitation light onto a subject; a return-light-image generating portion (61) and a fluorescence-image generating portion (62) that generate a return-light image (G1) and a fluorescence image (G2) of the subject, respectively; a fluorescence detecting portion (63) that detects a fluorescence region in the fluorescence image (G2); a return-light-image adjusting portion (65) that adjusts gradation values of the return-light image (G1); a superimposed-image generating portion (66) that generates a superimposed image (G3) by using the return-light image (G1'), in which the gradation values have been adjusted, and the fluorescence image (G2); and a coefficient setting portion (64) that sets, in the case in which the fluorescence region is detected by the fluorescence detecting portion (63), a degree-of-adjustment, by which the gradation values of the return-light image (G1) are adjusted by the return-light-image adjusting portion (65), so that the gradation values of the return-light image (G1) are decreased as compared with the case in which the fluorescence region is not detected by the fluorescence detecting portion (63).
摘要翻译：本发明提供一种荧光观察装置（100），其包括将照明光和激发光照射到被检体上的光源（3）分别产生被摄体的返回光图像（G1）和荧光图像（G2）的返回光图像生成部（61）和荧光图像生成部（62）检测荧光图像（G2）中的荧光区域的荧光检测部（63）。调整返回光图像（G1）的灰度值的返回光图像调整部（65）。通过使用调整了灰度值的返回光图像（G1'）和荧光图像（G2）来生成叠加图像（G3）的叠加图像生成部（66）。以及系数设定部（64），其在通过荧光检测部（63）检测出荧光区域的情况下设定调整度，通过该调节度，返回光图像（G1 ）通过返回光图像调整部（65）进行调整，使得与未被荧光检测部检测出荧光区域的情况相比，返回光图像（G1）的灰度值降低（63）。

10. 发明公开

EP2926713A1 OBSERVATION DEVICE 无效转让
标题翻译： BEOBACHTUNGSVORRICHTUNG
公开(公告)号：EP2926713A1
公开(公告)日：2015-10-07
申请号：EP13859294.4
申请日：2013-11-22
申请人： Olympus Corporation
发明人： KUBO, Kei , ISHIHARA, Yasushige , SHIDA, Hiromi
IPC分类号： A61B1/00 , A61B1/04 , G01N21/64 , G02B23/24 , G02B23/26
CPC分类号： A61B1/0638 , A61B1/00009 , A61B1/00186 , A61B1/043 , G02B23/2484 , G02B23/26 , H04N2005/2255
摘要： Provided is an observation apparatus (100) comprising a light source (3) that irradiates a subject (X) with illumination light and special light that acts on a specific region of the subject (X); a return-light-image generating portion (61) that generates a return-light image (G1) by capturing return light coming from the subject (X) due to irradiation with the illumination light; a special-light-image generating portion (62) that generates a special-light image (G2) by capturing signal light coming from the subject (X) due to irradiation with the special light; an extraction portion (63) that extracts the specific region from the special-light image (G2); and an enhancement processing portion (64) that performs enhancement processing, which is based on return-light image information, on the return-light image (G1), in a region corresponding to the extracted specific region.
摘要翻译：本发明提供一种观察装置（100），其具备照射被检体（X）的光源（3），该照明光和作用于被检体（X）的特定区域的特殊光; 返回光图像生成部（61），其通过从照明光照射而捕获来自被摄体（X）的返回光，生成返回光图像（G1）特殊光图像生成部（62），其特征在于：通过利用所述特殊光照射来捕捉来自所述被摄体（X）的信号光，生成特殊光图像（G2）提取部（63），从所述特殊光图像（G2）提取所述特定区域; 以及增强处理部分，在对应于所提取的特定区域的区域中，对返回光图像（G1）执行基于返回光图像信息的增强处理。

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